Prof. Dr. ID: 65683

Boris Fehse

graph of relations

Publications

  1. 2020
  2. Obituary Rolf Neth 1926-2020

    Fehse, B., Kröger, N., Stocking, C. & Zander, A., 05.2020, In: Experimental hematology. 85, p. 1-2 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Transfer

  3. A High-Throughput HIV-1 Drug Screening Platform, Based on Lentiviral Vectors and Compatible with Biosafety Level-1

    Ellinger, B., Pohlmann, D., Woens, J., Jäkel, F. M., Reinshagen, J., Stocking, C., Prassolov, V. S., Fehse, B. & Riecken, K., 25.05.2020, In: VIRUSES-BASEL. 12, 5

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Excellent proliferation and persistence of allogeneic donor-derived 41-BB based CAR-T cells despite immunosuppression with cyclosporine A

    Ayuk, F., Fehse, B., Janson, D., Berger, C., Riecken, K. & Kröger, N., 06.2020, In: HAEMATOLOGICA. 105, 6, p. 322-324 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  5. Clonal Evolution after Allogeneic Hematopoietic Stem Cell Transplantation

    Christopeit, M., Badbaran, A., Alawi, M., Flach, J., Fehse, B. & Kröger, N., 07.2020, In: BIOL BLOOD MARROW TR. 26, 7, p. e167-e170

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Suicide gene therapy for the treatment of high-grade glioma: past lessons, present trends, and future prospects

    Hossain, J. A., Marchini, A., Fehse, B., Bjerkvig, R. & Miletic, H., 10.07.2020, In: NEURO-ONCOL ADV. 2, 1, p. vdaa013

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  7. Correction: Role of growth arrest-specific gene 6-mer axis in multiple myeloma

    Waizenegger, J. S., Ben-Batalla, I., Weinhold, N., Meissner, T., Wroblewski, M., Janning, M., Riecken, K., Binder, M., Atanackovic, D., Taipaleenmaeki, H., Schewe, D., Sawall, S., Gensch, V., Cubas-Cordova, M., Seckinger, A., Atanackovic, D., Hesse, E., Kröger, N., Fehse, B., Hose, D., Klein, B., Raab, M. S., Pantel, K., Bokemeyer, C. & Loges, S., 09.2020, In: LEUKEMIA. 34, 9, p. 2542

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  8. Development of CAR-T cell therapies for multiple myeloma

    Gagelmann, N., Riecken, K., Wolschke, C., Berger, C., Ayuk, F. A., Fehse, B. & Kröger, N., 09.2020, In: LEUKEMIA. 34, 9, p. 2317-2332 16 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  9. Intravitreal Co-Administration of GDNF and CNTF Confers Synergistic and Long-Lasting Protection against Injury-Induced Cell Death of Retinal Ganglion Cells in Mice

    Dulz, S., Bassal, M., Flachsbarth, K., Riecken, K., Fehse, B., Schlichting, S., Bartsch, S. & Bartsch, U., 11.09.2020, In: CELLS-BASEL. 9, 9

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Glioma escape signature and clonal development under immune pressure

    Maire, C. L., Mohme, M., Bockmayr, M., Fita, K. D., Riecken, K., Börnigen, D., Alawi, M., Failla, A. V., Kolbe, K., Zapf, S., Holz, M., Neumann, K., Dührsen, L., Lange, T., Fehse, B., Westphal, M. & Lamszus, K., 01.10.2020, In: J CLIN INVEST. 130, 10, p. 5257-5271 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Overcoming the delivery problem for therapeutic genome editing: Current status and perspective of non-viral methods

    Mashel, T. V., Tarakanchikova, Y. V., Muslimov, A. R., Zyuzin, M. V., Timin, A. S., Lepik, K. V. & Fehse, B., 11.2020, In: BIOMATERIALS. 258, p. 120282

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  12. 2021
  13. Einleitung: Gentechnologien in Deutschland im Fokus der IAG Gentechnologiebericht

    Fehse, B., Marx-Stölting, L., Schickl, H. & Khachatryan, A., 2021, Fünfter Gentechnologiebericht: Sachstand und Perspektiven für Forschung und Anwendung. Fehse, B., Hucho, F., Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Marx-Stölting, L., Mundlos, S., Osterheider, A., Pichl, A., Reich, J., Schickl, H., Schicktanz, S., Taupitz, J., Walter, J., Winkler, E. & Zenke, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 81-86 6 p. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 44).

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesTransfer

  14. Genome-Editing und Einzelzellanalyse: Neue Methoden und ihre Implikationen für Forschung, Anwendung und Gesellschaft

    Fehse, B., Walter, J., Reich, J., Marx-Stölting, L., Pichl, A. & Schickl, H., 2021, Fünfter Gentechnologiebericht: Sachstand und Perspektiven für Forschung und Anwendung. Fehse, B., Hucho, F., Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Marx-Stölting, L., Mundlos, S., Osterheider, A., Pichl, A., Reich, J., Schickl, H., Schicktanz, S., Taupitz, J., Walter, J., Winkler, E. & Zenke, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 219-250 32 p. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 44).

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesTransfer

  15. mRNA Transfection of T-Lymphocytes by Electroporation

    Schwarze, L-I. & Fehse, B., 2021, In: Methods Mol Biol. 2285, p. 217-226 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Neubewertung des Schutzes von In-vitro-Embryonen in Deutschland

    Bartram, C. R., Ellenberg, J., Fehse, B., Friedrich, B., Kentenich, H., Kumsta, R., Niehrs, C., Nöthen, M. M., Schöne-Seifert, B., Tanner, K., Taupitz, J., Thorn, P., Vogel, J., Wiesemann, C. & Winnacker, E-L., 2021

    Research output: Memorandum/expositionAcademic memorandum

  17. Themenbereich somatische Gentherapie: aus dem Labor über klinische Studien zum kommerziellen Einsatz

    Fehse, B., 2021, Fünfter Gentechnologiebericht: Sachstand und Perspektiven für Forschung und Anwendung. Fehse, B., Hucho, F., Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Marx-Stölting, L., Mundlos, S., Osterheider, A., Pichl, A., Reich, J., Schickl, H., Schicktanz, S., Taupitz, J., Walter, J., Winkler, E. & Zenke, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 156-183 28 p. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften).

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesTransfer

  18. Anwendung des Genome Editing in der somatischen Gentherapie: Eine Einführung

    Fehse, B. & Abramowski-Mock, U., 03.2021, Anwendung des Genome Editing in der somatischen Gentherapie. 1 ed. Wiesbaden: Springer, 48 p. (essentials).

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesTransfer

  19. SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2

    von Wenserski, L., Schultheiß, C., Bolz, S., Schliffke, S., Simnica, D., Willscher, E., Gerull, H., Wolters-Eisfeld, G., Riecken, K., Fehse, B., Altfeld, M., Nollau, P. & Binder, M., 04.2021, In: LEUKEMIA. 35, 4, p. 1073-1086 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Multiple genes surrounding Bcl-xL, a common retroviral insertion site, can influence hematopoiesis individually or in concert

    Ha, T-C., Stahlhut, M., Rothe, M., Paul, G., Dziadek, V., Morgan, M. A., Brugman, M., Fehse, B., Kustikova, O., Schambach, A. & Baum, C., 05.2021, In: HUM GENE THER. 32, 9-10, p. 458-472 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Axicabtagene ciloleucel in vivo expansion and treatment outcome in aggressive B-cell lymphoma in a real-world setting

    Ayuk, F. A., Berger, C., Badbaran, A., Zabelina, T., Sonntag, T., Riecken, K., Geffken, M., Wichmann, D., Frenzel, C., Thayssen, G., Zeschke, S., Kröger, N. & Fehse, B., 08.06.2021, In: BLOOD ADV. 5, 11, p. 2523-2527 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Efficient Pseudotyping of Different Retroviral Vectors Using a Novel, Codon-Optimized Gene for Chimeric GALV Envelope

    Mirow, M., Schwarze, L. I., Fehse, B. & Riecken, K., 27.07.2021, In: VIRUSES-BASEL. 13, 8, 1471.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Vertically transferred maternal immune cells promote neonatal immunity against early life infections

    Stelzer, I., Urbschat, C., Schepanski, S., Thiele, K., Triviai, I., Wieczorek, A., Alawi, M., Ohnezeit, D., Kottlau, J., Huang, J., Fischer, N., Mittrücker, H-W., Solano, M. E., Fehse, B., Diemert, A., Stahl, F. & Arck, P., 04.08.2021, In: NAT COMMUN. 12, 1, p. 4706

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Automated production of CCR5-negative CD4+-T cells in a GMP-compatible, clinical scale for treatment of HIV-positive patients

    Schwarze, L. I., Sonntag, T., Wild, S., Schmitz, S., Uhde, A. & Fehse, B., 09.2021, In: GENE THER. 28, 9, p. 572-587 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application

    Schwarze, L. I., Głów, D., Sonntag, T., Uhde, A. & Fehse, B., 09.2021, In: GENE THER. 28, 9, p. 588-601 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Retroviral gene therapy in Germany with a view on previous experience and future perspectives

    Morgan, M. A., Galla, M., Grez, M., Fehse, B. & Schambach, A., 09.2021, In: GENE THER. 28, 9, p. 494-512 19 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  27. Two cases of T cell lymphoma following Piggybac-mediated CAR T cell therapy

    Schambach, A., Morgan, M. & Fehse, B., 01.09.2021, In: MOL THER. 29, 9, p. 2631-2633 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  28. LATE-a novel sensitive cell-based assay for the study of CRISPR/Cas9-related long-term adverse treatment effects

    Głów, D., Meyer, S., García Roldán, I., Akingunsade, L. M., Riecken, K. & Fehse, B., 10.09.2021, In: MOL THER-METH CLIN D. 22, p. 249-262 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets

    Carlet, M., Völse, K., Vergalli, J., Becker, M., Herold, T., Arner, A., Senft, D., Jurinovic, V., Liu, W-H., Gao, Y., Dill, V., Fehse, B., Baldus, C. D., Bastian, L., Lenk, L., Schewe, D. M., Bagnoli, J. W., Vick, B., Schmid, J. P., Wilhelm, A., Marschalek, R., Jost, P. J., Miething, C., Riecken, K., Schmidt-Supprian, M., Binder, V. & Jeremias, I., 27.09.2021, In: NAT COMMUN. 12, 1, p. 5655

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Gene Therapy "Made in Germany": A Historical Perspective, Analysis of the Status Quo, and Recommendations for Action by the German Society for Gene Therapy

    Büning, H., Fehse, B., Ivics, Z., Kochanek, S., Koehl, U., Kupatt, C., Mussolino, C., Nettelbeck, D. M., Schambach, A., Uckert, W., Wagner, E. & Cathomen, T., 10.2021, In: HUM GENE THER. 32, 19-20, p. 987-996 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. How to package and SEND mRNA: a novel "humanized" vector system based on endogenous retroviruses

    Riecken, K., Glow, D. & Fehse, B., 05.11.2021, In: SIGNAL TRANSDUCT TAR. 6, 1, 384.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  32. Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia

    Greinacher, A., Selleng, K., Palankar, R., Wesche, J., Handtke, S., Wolff, M., Aurich, K., Lalk, M., Methling, K., Volker, U., Hentschker, C., Michalik, S., Steil, L., Reder, A., Schönborn, L., Beer, M., Franzke, K., Büttner, A., Fehse, B., Stavrou, E. X., Rangaswamy, C., Mailer, R. K., Englert, H., Frye, M., Thiele, T., Kochanek, S., Krutzke, L., Siegerist, F., Endlich, N., Warkentin, T. E. & Renné, T., 02.12.2021, In: BLOOD. 138, 22, p. 2256-2268 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Digital PCR to quantify ChAdOx1 nCoV-19 copies in blood and tissues

    Badbaran, A., Mailer, R. K., Dahlke, C., Woens, J., Fathi, A., Mellinghoff, S. C., Renné, T., Addo, M. M., Riecken, K. & Fehse, B., 10.12.2021, In: MOL THER-METH CLIN D. 23, p. 418-423 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. CRISPR-to-Kill (C2K)–Employing the Bacterial Immune System to Kill Cancer Cells

    Glow, D., Maire, C., Schwarze, L-I., Lamszus, K. & Fehse, B., 15.12.2021, In: CANCERS. 13, 24, 6306.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. CAR-HEMATOTOX: A model for CAR T-cell related hematological toxicity in relapsed/refractory large B-cell lymphoma

    Rejeski, K., Perez Perez, A., Sesques, P., Hoster, E., Berger, C. S., Jentzsch, L., Mougiakakos, D., Frölich, L., Ackermann, J., Buecklein, V., Blumenberg, V., Schmidt, C., Jallades, L., Fehse, B., Faul, C., Karschnia, P., Weigert, O., Dreyling, M., Locke, F. L., von Bergwelt-Baildon, M., Mackensen, A., Bethge, W. A., Ayuk, F., Bachy, E., Salles, G. A., Jain, M. D. & Subklewe, M., 16.12.2021, In: BLOOD. 138, 24, p. 2499-2513 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. 2022
  37. Immune Monitoring

    Berger, S. C., Fehse, B. & Rubio, M-T., 2022, The EBMT/EHA CAR-T Cell Handbook. Kröger, N., Gribben, J., Chabannon, C., Yakoub-Agha, I. & Einsele, H. (eds.). 1 ed. Cham: Springer International Publishing, p. 177-182 6 p.

    Research output: SCORING: Contribution to book/anthologyChapterResearch

  38. Influence of Fetomaternal Microchimerism on Maternal NK Cell Reactivity against the Child's Leukemic Blasts

    Martin, L-M., Kruchen, A., Fehse, B. & Müller, I., 04.03.2022, In: BIOMEDICINES. 10, 3, 603.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. The Reconstitution Dynamics of Cultivated Hematopoietic Stem Cells and Progenitors Is Independent of Age

    Gotzhein, F., Aranyossy, T., Thielecke, L., Sonntag, T., Thaden, V., Fehse, B., Müller, I., Glauche, I. & Cornils, K., 15.03.2022, In: INT J MOL SCI. 23, 6, 3160.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Combined Targeting of AKT and mTOR Inhibits Tumor Formation of EpCAM+ and CD90+ Human Hepatocellular Carcinoma Cells in an Orthotopic Mouse Model

    Moustafa, M., Dähling, K-K., Günther, A., Riebandt, L., Smit, D. J., Riecken, K., Schröder, C., Zhuang, R., Krech, T., Kriegs, M., Fehse, B., Izbicki, J., Fischer, L., Nashan, B., Li, J. & Jücker, M., 08.04.2022, In: CANCERS. 14, 8, 1882.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Comparison of single copy gene‑based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19‑directed CAR T cells in treated patients

    Schubert, M-L., Berger, C., Kunz, A., Schmitt, A., Badbaran, A., Neuber, B., Zeschke, S., Wang, L., Riecken, K., Hückelhoven-Krauss, A., Müller, I., Müller-Tidow, C., Dreger, P., Kröger, N., Ayuk, F. A., Schmitt, M. & Fehse, B., 05.2022, In: INT J ONCOL. 60, 5, 48.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Population Pharmacokinetics of Busulfan and Its Metabolite Sulfolane in Patients with Myelofibrosis Undergoing Hematopoietic Stem Cell Transplantation

    Dadkhah, A., Wicha, S. G., Kröger, N., Müller, A., Pfaffendorf, C., Riedner, M., Badbaran, A., Fehse, B. & Langebrake, C., 27.05.2022, In: PHARMACEUTICS. 14, 6, 1145.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. High-throughput drug screening allowed identification of entry inhibitors specifically targeting different routes of SARS-CoV-2 Delta and Omicron/BA.1

    Kuzikov, M., Woens, J., Zaliani, A., Hambach, J., Eden, T., Fehse, B., Ellinger, B. & Riecken, K., 07.2022, In: BIOMED PHARMACOTHER. 151, 113104.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Natural killer cell-mediated ADCC in SARS-CoV-2-infected individuals and vaccine recipients

    Hagemann, K., Riecken, K., Jung, J., Hildebrandt, H., Menzel, S., Bunders, M., Fehse, B., Koch-Nolte, F., Heinrich, F., Peine, S., Schulze Zur Wiesch, J., Brehm, T. T., Addo, M. M., Lütgehetmann, M. & Altfeld, M., 08.2022, In: EUR J IMMUNOL. 52, 8, p. 1297-1307 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. 2023
  46. Correction: Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application

    Schwarze, L. I., Głów, D., Sonntag, T., Uhde, A. & Fehse, B., 02.2023, In: GENE THER. 30, 1-2, p. 187

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  47. Molecular monitoring of T-cell kinetics and migration in severe neurotoxicity after real-world CD19-specific chimeric antigen receptor-T cell therapy

    Berger, S. C., Fehse, B., Akyüz, N., Geffken, M., Wolschke, C., Janson, D., Gagelmann, N., Luther, M., Wichmann, D., Frenzel, C., Thayssen, G., Alegiani, A., Badbaran, A., Zeschke, S., Dierlamm, J., Kröger, N. & Ayuk, F. A., 01.02.2023, In: HAEMATOLOGICA. 108, 2, p. 444-456 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Microglia colonize the developing brain by clonal expansion of highly proliferative progenitors, following allometric scaling

    Barry-Carroll, L., Greulich, P., Marshall, A. R., Riecken, K., Fehse, B., Askew, K. E., Li, K., Garaschuk, O., Menassa, D. A. & Gomez-Nicola, D., 30.05.2023, In: CELL REP. 42, 5, p. 112425

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Donor Lymphocyte Infusion and Molecular Monitoring for Relapsed Myelofibrosis After Hematopoietic Cell Transplantation

    Gagelmann, N., Wolschke, C., Badbaran, A., Janson, D., Berger, C., Klyuchnikov, E., Ayuk, F., Fehse, B. & Kröger, N., 07.2023, In: HEMASPHERE. 7, 7, p. e921

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Spleen volume and length determined by computed tomography impact outcome after allogeneic stem cell transplantation for myelofibrosis

    Luther, M., Henes, F. O., Zabelina, T., Massoud, R., Janson, D., Wolschke, C., Klyuchnikov, E., Gagelmann, N., Fehse, B., Adam, G., Kröger, N. & Ayuk, F., 07.2023, In: BONE MARROW TRANSPL. 58, 7, p. 755-761 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Deep Characterization and Comparison of Different Retrovirus-like Particles Preloaded with CRISPR/Cas9 RNPs

    Wichmann, M., Maire, C. L., Nuppenau, N., Habiballa, M., Uhde, A., Kolbe, K., Schröder, T., Lamszus, K., Fehse, B. & Głów, D., 13.07.2023, In: INT J MOL SCI. 24, 14, p. 11399

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal

    Grochowska, K. M., Sperveslage, M., Raman, R., Failla, A. V., Głów, D., Schulze, C., Laprell, L., Fehse, B. & Kreutz, M. R., 29.08.2023, In: CELL REP. 42, 8, p. 112998

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review