Prof. Dr. ID: 65683

Boris Fehse

graph of relations

Publications

  1. 2016
  2. Digital PCR to assess gene-editing frequencies (GEF-dPCR) mediated by designer nucleases

    Mock, U., Hauber, I. & Fehse, B., 03.2016, In: NAT PROTOC. 11, 3, p. 598-615 18 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Investigation of the Mesenchymal Stem Cell Compartment by Means of a Lentiviral Barcode Library

    Bigildeev, A. E., Cornils, K., Aranyossy, T., Sats, N. V., Petinati, N. A., Shipounova, I. N., Surin, V. L., Pshenichnikova, O. S., Riecken, K., Fehse, B. & Drize, N. I., 04.2016, In: BIOCHEMISTRY-MOSCOW+. 81, 4, p. 373-81 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes

    Labenski, V., Suerth, J. D., Barczak, E., Heckl, D., Levy, C., Bernadin, O., Charpentier, E., Williams, D. A., Fehse, B., Verhoeyen, E. & Schambach, A., 26.04.2016, In: BIOMATERIALS. 97, p. 97-109 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Massive Clonal Selection and Transiently Contributing Clones During Expansion of Mesenchymal Stem Cell Cultures Revealed by Lentiviral RGB-Barcode Technology

    Selich, A., Daudert, J., Hass, R., Philipp, F., von Kaisenberg, C., Paul, G., Cornils, K., Fehse, B., Rittinghausen, S., Schambach, A. & Rothe, M., 05.2016, In: STEM CELL TRANSL MED. 5, 5, p. 591-601 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer

    Bierwolf, J., Volz, T., Lütgehetmann, M., Allweiss, L., Riecken, K., Warlich, M., Fehse, B., Kalff, J. C., Dandri-Petersen, M. & Pollok, J-M., 05.2016, In: TISSUE ENG PT A. 22, 9-10, p. 742-53 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Long-term in vivo single-cell tracking reveals the switch of migration patterns in adult-born juxtaglomerular cells of the mouse olfactory bulb

    Liang, Y., Li, K., Riecken, K., Maslyukov, A., Gomez-Nicola, D., Kovalchuk, Y., Fehse, B. & Garaschuk, O., 07.2016, In: CELL RES. 26, 7, p. 805-21 17 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Microglia regulate hippocampal neurogenesis during chronic neurodegeneration

    De Lucia, C., Rinchon, A., Olmos-Alonso, A., Riecken, K., Fehse, B., Boche, D., Perry, V. H. & Gomez-Nicola, D., 07.2016, In: BRAIN BEHAV IMMUN. 55, p. 179-190

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Mesenchymal Stromal/Stem Cells Do Not Ameliorate Experimental Autoimmune Encephalomyelitis and Are Not Detectable in the Central Nervous System of Transplanted Mice

    Abramowski, P., Krasemann, S., Ernst, T., Lange, C., Ittrich, H., Schweizer, M., Zander, A. R., Martin, R. & Fehse, B., 01.08.2016, In: STEM CELLS DEV. 25, 15, p. 1134-48

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Lentiviral HSV-Tk.007-mediated suicide gene therapy is not toxic for normal brain cells

    Hossain, J. A., Ystaas, L. R., Mrdalj, J., Välk, K., Riecken, K., Fehse, B., Bjerkvig, R., Grønli, J. & Miletic, H., 09.2016, In: J GENE MED. 18, 9, p. 234-43 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Similar outcome of calreticulin type I and calreticulin type II mutations following RIC allogeneic haematopoietic stem cell transplantation for myelofibrosis

    Christopeit, M., Badbaran, A., Zabelina, T., Zeck, G., Fehse, B., Ayuketang, F. A., Wolschke, C. & Kröger, N-M., 10.2016, In: BONE MARROW TRANSPL. 51, 10, p. 1391-1393 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Potent in vitro and in vivo effects of polyclonal anti-human-myeloma globulins

    Schieferdecker, A., Shoshani, O., Westner, B., Zipori, D., Fehse, B., Kröger, N. & Ayuketang, F. A., 11.10.2016, In: ONCOTARGET. 7, 41, p. 67061-67070

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Генная терапия на основе трансплантации гемопоэтичеcких стволовых клеток с использованием сайт-специфического редактирования генома

    Lepik, K. V., Popova, M. O., Shakirova, A. I. S., Sergeev, V. S., Potter, A. Y., Barkhatov, I. M., Fehse, B. & Afanasyev, B. V., 11.2016, In: Genes & Cells (гены & клетки) . XI, 2, p. 21-31

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Достижения в разработке инструментов для редактирования генома.

    Fehse, B., 11.2016, АЛЬМАНАХ 2016: РЕДАКТИРОВАНИЕ ГЕНОМА И ВОЗМОЖНОСТИ ГЕННОЙ ТЕРАПИИ В ОНКОЛОГИИ. 1 ed. Moskau, 4 p. 1

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesTransfer

  15. 2017
  16. Mesenchymal stem cells engineering: microcapsules assisted gene transfection and magnetic cell separation.

    Muslimov, A. R., Timin, A. S., Petrova, AV., Epifanovskaya, O. S., Shakirova, A. I., Lepik, K. V., Gorshkov, A., Il’inskaja, EV., Vasin, A. V., Afanasyev, B. V., Fehse, B. & Sukhorukov, G. B., 2017, In: ACS BIOMATER SCI ENG. 3, 10, p. 2314-2324

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-KPolymorphism

    Braig, F., Kriegs, M., Voigtlaender, M., Habel, B., Grob, T., Biskup, K., Blanchard, V., Sack, M., Thalhammer, A., Ben Batalla, I., Braren, I., Laban, S., Danielczyk, A., Goletz, S., Jakubowicz, E., Märkl, B., Trepel, M., Knecht, R., Riecken, K., Fehse, B., Loges, S., Bokemeyer, C. & Binder, M., 01.03.2017, In: CANCER RES. 77, 5, p. 1188-1199 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Optical Barcoding for Single-Clone Tracking to Study Tumor Heterogeneity

    Mohme, M., Maire, C. L., Riecken, K., Zapf, S., Aranyossy, T., Westphal, M., Lamszus, K. & Fehse, B., 01.03.2017, In: MOL THER. 25, 3, p. 621-633

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Limitations and challenges of genetic barcode quantification

    Thielecke, L., Aranyossy, T., Dahl, A., Tiwari, R., Roeder, I., Geiger, H., Fehse, B., Glauche, I. & Cornils, K., 03.03.2017, In: SCI REP-UK. 7, p. 43249

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis

    Riedel, J-H., Becker, M., Kopp, K., Düster, M., Brix, S. R., Meyer-Schwesinger, C., Kluth, L. A., Gnirck, A-C., Attar, M., Krohn, S., Fehse, B., Stahl, R. A. K., Panzer, U. & Turner, J-E., 07.2017, In: J AM SOC NEPHROL. 28, 7, p. 2068-2080

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Impact of Molecular Genetics on Outcome in Myelofibrosis Patients after Allogeneic Stem Cell Transplantation

    Kröger, N., Panagiota, V., Badbaran, A., Zabelina, T., Triviai, I., Araujo Cruz, M. M., Shahswar, R., Ayuketang, F. A., Gehlhaar, M., Wolschke, C., Bollin, R., Walter, C., Dugas, M., Wiehlmann, L., Lehmann, U., Koenecke, C., Chaturvedi, A., Alchalby, H., Stadler, M., Eder, M., Christopeit, M., Göhring, G., Koenigsmann, M., Schlegelberger, B., Kreipe, H-H., Ganser, A., Stocking, C., Fehse, B., Thol, F. & Heuser, M., 07.2017, In: BIOL BLOOD MARROW TR. 23, 7, p. 1095-1101

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion

    Cornils, K., Thielecke, L., Winkelmann, D., Aranyossy, T., Lesche, M., Dahl, A., Roeder, I., Fehse, B. & Glauche, I., 14.07.2017, In: MOL CANCER. 16, 1, p. 120

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Gene and Cell Therapy in Germany

    von Kalle, C., Fehse, B. & Büning, H., 10.2017, In: HUM GENE THER. 28, 10, p. 781

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  24. Genetic barcodes facilitate competitive clonal analyses in vivo

    Aranyossy, T., Thielecke, L., Glauche, I., Fehse, B. & Cornils, K., 10.2017, In: HUM GENE THER. 28, 10, p. 926-937

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Impact of molecular residual disease post allografting in myelofibrosis patients

    Wolschke, C., Badbaran, A., Zabelina, T., Christopeit, M., Ayuketang, F. A., Triviai, I., Zander, A., Alchalby, H., Bacher, U., Fehse, B. & Kröger, N-M., 11.2017, In: BONE MARROW TRANSPL. 52, 11, p. 1526-1529

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. SHIP1, but not an AML-derived SHIP1 mutant, suppresses myeloid leukemia growth in a xenotransplantation mouse model

    Täger, M., Horn, S., Latuske, E., Ehm, P., Schaks, M., Nalaskowski, M., Fehse, B., Fiedler, W., Stocking, C., Wellbrock, J. & Jücker, M., 11.2017, In: GENE THER. 24, 11, p. 749-753 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Multi-color RGB marking enables clonality assessment of liver tumors in a murine xenograft model

    Thomaschewski, M., Riecken, K., Unrau, L., Volz, T., Cornils, K., Ittrich, H., Heim, D., Wege, H., Akgün, E., Lütgehetmann, M., Dieckhoff, J., Köpke, M., Dandri, M., Benten, D. & Fehse, B., 29.12.2017, In: ONCOTARGET. 8, 70, p. 115582-115595 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. 2018
  29. Genomeditierung durch CRISPR und Co

    Fehse, B., 2018, Stammzellforschung: Aktuelle wissenschaftliche und gesellschaftliche Entwicklungen. Zenke, M., Marx-Stölting, L. & Schickl, H. (eds.). 1 ed. Baden-Baden: Nomos, p. 97-114 18 p. 4. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 39).

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesTransfer

  30. „Rote Gentechnologie“ – Nachhaltiges Comeback der Gentherapie?!

    Fehse, B., 2018, Vierter Gentechnologiebericht : Bilanzierung einer Hochtechnologie. Hucho, F., Diekämper, J., Fangerau, H., Fehse, B., Hampel, J., Köchy, K., Könninger, S., Marx-Stölting, L., Müller-Röber, B., Reich, J., Schickl, H., Taupitz, J., Walter, J., Zenke, M. & Korte, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 210-214 5 p. (Forschungsberichte der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 40).

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesTransfer

  31. Efficient gene editing via non-viral delivery of CRISPR-Cas9 system using polymeric and hybrid microcarriers

    Timin, A. S., Muslimov, A. R., Lepik, K. V., Epifanovskaya, O. S., Shakirova, A. I., Mock, U., Riecken, K., Okilova, M. V., Sergeev, V. S., Afanasyev, B. V., Fehse, B. & Sukhorukov, G. B., 01.2018, In: NANOMED-NANOTECHNOL. 14, 1, p. 97-108 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. High bone turnover in mice carrying a pathogenic Notch2-mutation causing Hajdu-Cheney syndrome

    Vollersen, N., Hermans-Borgmeyer, I., Cornils, K., Fehse, B., Rolvien, T., Triviai, I., Jeschke, A., Oheim, R., Amling, M., Schinke, T. & Yorgan, T. A., 01.2018, In: J BONE MINER RES. 33, 1, p. 70-83 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. The Time Is Ripe for Somatic Genome Editing: NIH Program to Strengthen Translation

    Fehse, B. & Abramowski-Mock, U., 07.03.2018, In: MOL THER. 26, 3, p. 671-674 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  34. Locally Ablative Radiation Therapy of a Primary Human Small Cell Lung Cancer Tumor Decreases the Number of Spontaneous Metastases in Two Xenograft Models

    Frenzel, T., Siekmann, J., Grohmann, C., Valentiner, U., Schmitz, R., Riecken, K., Fehse, B., Schumacher, U., Lange, T. & Krüll, A., 15.03.2018, In: INT J RADIAT ONCOL. 100, 4, p. 1044-1056 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. The phosphotyrosine phosphatase SHP2 promotes anergy in chronic lymphocytic leukemia

    Schliffke, S., Buhs, S., Bolz, S., Gerull, H., von Wenserski, L., Riecken, K., Fehse, B., Nollau, P. & Binder, M., 12.04.2018, In: BLOOD. 131, 15, p. 1755-1758 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks

    Brenière-Letuffe, D., Domke-Shibamiya, A., Hansen, A., Eschenhagen, T., Fehse, B., Riecken, K. & Stenzig, J., 18.06.2018, In: STEM CELL RES THER. 9, 1, p. 165

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma

    Roh, V., Abramowski, P., Hiou-Feige, A., Cornils, K., Rivals, J-P., Zougman, A., Aranyossy, T., Thielecke, L., Truan, Z., Mermod, M., Monnier, Y., Prassolov, V., Glauche, I., Nowrouzi, A., Abdollahi, A., Fehse, B., Simon, C. & Tolstonog, G. V., 20.11.2018, In: CELL REP. 25, 8, p. 2208-2222.e7

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China

    Büning, H., Griesenbach, U., Fehse, B., Ylä-Herttuala, S., Anagnou, N. P., van Beusechem, V., Raya, A. & Verhoeyen, E., 12.2018, In: HUM GENE THER. 29, 12, p. 1337–1338 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Transfer

  39. Transient Retrovirus-Based CRISPR/Cas9 All-in-One Particles for Efficient, Targeted Gene Knockout

    Knopp, Y., Geis, F. K., Heckl, D., Horn, S., Neumann, T., Kuehle, J., Meyer, J., Fehse, B., Baum, C., Morgan, M., Meyer, J., Schambach, A. & Galla, M., 07.12.2018, In: MOL THER-NUCL ACIDS. 13, p. 256-274 19 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. 2019
  41. Cancer Cells Expressing Oncogenic Rat Sarcoma Show Drug-Addiction Toward Epidermal Growth Factor Receptor Antibodies Mediated by Sustained MAPK Signaling

    Tintelnot, J., Metz, S., Trentmann, M., Oberle, A., von Wenserski, L., Schultheiß, C., Braig, F., Kriegs, M., Fehse, B., Riecken, K., Bokemeyer, C., Stein, A. & Binder, M., 2019, In: FRONT ONCOL. 9, p. 1559

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Cancer Suicide Gene Therapy with TK.007

    Hossain, J. A., Riecken, K., Miletic, H. & Fehse, B., 2019, In: Methods Mol Biol. 1895, p. 11-26 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Cellular Therapy with Engineered T Cells, Efficacy and Side Effects

    Bondanza, A., Bonini, C., Fehse, B. & Hudecek, M., 2019, The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies: The EBMT Handbook. Carreras, E., Dufour, C., Mohty, M. & Kröger, N. (eds.). 1 ed. Springer Nature Switzerland AG, p. 449-456 8 p.

    Research output: SCORING: Contribution to book/anthologyChapterResearch

  44. Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours

    Ricklefs, F. L., Maire, C. L., Reimer, R., Dührsen, L., Kolbe, K., Holz, M., Schneider, E., Rissiek, A., Babayan, A., Hille, C., Pantel, K., Krasemann, S., Glatzel, M., Heiland, D. H., Flitsch, J., Martens, T., Schmidt, N. O., Peine, S., Breakefield, X. O., Lawler, S., Chiocca, E. A., Fehse, B., Giebel, B., Görgens, A., Westphal, M. & Lamszus, K., 2019, In: J EXTRACELL VESICLES. 8, 1, p. 1588555

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo

    Giersch, K., Bhadra, O. D., Volz, T., Allweiss, L., Riecken, K., Fehse, B., Lohse, A. W., Petersen, J., Sureau, C., Urban, S., Dandri, M. & Lütgehetmann, M., 01.2019, In: GUT. 68, 1, p. 150-157 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Nanobody-targeting of epidermal growth factor receptor (EGFR) ectodomain variants overcomes resistance to therapeutic EGFR antibodies

    Tintelnot, J., Baum, N., Schultheiss, C., Braig, F., Trentmann, M., Finter, J., Fumey, W., Bannas, P., Fehse, B., Riecken, K., Schütze, K., Bokemeyer, C., Rösner, T., Valerius, T., Peipp, M., Koch-Nolte, F. & Binder, M., 04.2019, In: MOL CANCER THER. 18, 4, p. 823-833 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma

    Hossain, J. A., Latif, M. A., Ystaas, L. A. R., Ninzima, S., Riecken, K., Muller, A., Azuaje, F., Joseph, J. V., Talasila, K. M., Ghimire, J., Fehse, B., Bjerkvig, R. & Miletic, H., 11.07.2019, In: NEURO-ONCOLOGY. 21, 7, p. 890-900 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Chancen und Risiken der CAR-T-Zell-Therapie

    Ayuk, F. A., Fehse, B., Berger, S. C., Riecken, K. & Kroger, N., 10.2019, In: Hamb Ärztebl. 73, 10, p. 30-32

    Research output: SCORING: Contribution to journalSCORING: Review articleEducation

  49. Is multiple sclerosis progression associated with the HLA-DR15 haplotype?

    Stürner, K. H., Siembab, I., Schön, G., Stellmann, J-P., Heidari, N., Fehse, B., Heesen, C., Eiermann, T. H., Martin, R. & Binder, T. M., 17.12.2019, In: Mult Scler J-Exp Transl Clin. 5, 4, p. 2055217319894615

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. 2020
  51. Nanobody-based CD38-specific heavy chain antibodies induce killing of multiple myeloma and other hematological malignancies

    Schriewer, L., Schütze, K., Petry, K., Hambach, J., Fumey, W., Koenigsdorf, J., Baum, N., Menzel, S., Rissiek, B., Riecken, K., Fehse, B., Röckendorf, J. L., Schmid, J., Albrecht, B., Pinnschmidt, H., Ayuk, F., Kröger, N., Binder, M., Schuch, G., Hansen, T., Haag, F., Adam, G., Koch-Nolte, F. & Bannas, P., 2020, In: THERANOSTICS. 10, 6, p. 2645-2658 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs)

    Hambach, J., Riecken, K., Cichutek, S., Schütze, K., Albrecht, B., Petry, K., Röckendorf, J. L., Baum, N., Kröger, N., Hansen, T., Schuch, G., Haag, F., Adam, G., Fehse, B., Bannas, P. & Koch-Nolte, F., 29.01.2020, In: CELLS-BASEL. 9, 2

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. Digital PCR Assays for Precise Quantification of CD19-CAR-T Cells after Treatment with Axicabtagene Ciloleucel

    Fehse, B., Badbaran, A., Berger, C., Sonntag, T., Riecken, K., Geffken, M., Kröger, N. & Ayuk, F. A., 13.03.2020, In: MOL THER-METH CLIN D. 16, p. 172-178 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review