Dr.med. ID: 33796
Kai Lehmberg
Group leader
Publications
- 2023
Development of a centralised triage centre for children with cancer and blood disorders in response to the humanitarian crisis in Ukraine
Salek, M., Mueller, A., Alanbousi, I., Cepowska, Z., Dutkiewicz, M., Earl, J., Evseev, D., Kizyma, R., Kliuchkivska, K., Kolodrubiec, J., Matczak, K., Nogovitsyna, Y., Oszer, A., Pogorelyy, M., Raciborska, A., Rasul, S., Sokolowski, I., Sopilnyak, A., Vinitsky, A., Wlodarski, M. W., Wobst, N., Yakimkova, T., Rodriguez-Galindo, C., Wise, P. H., Mlynarski, W., Agulnik, A. & SAFER Ukraine Collaborative, 12.2023, In: LANCET ONCOL. 24, 12, p. 1315-1318 4 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Prospective Newborn Screening for SCID in Germany: A First Analysis by the Pediatric Immunology Working Group (API)
Speckmann, C., Nennstiel, U., Hönig, M., Albert, M. H., Ghosh, S., Schuetz, C., Brockow, I., Hörster, F., Niehues, T., Ehl, S., Wahn, V., Borte, S., Lehmberg, K., Baumann, U., Beier, R., Krüger, R., Bakhtiar, S., Kuehl, J-S., Klemann, C., Kontny, U., Holzer, U., Meinhardt, A., Morbach, H., Naumann-Bartsch, N., Rothoeft, T., Kreins, A. Y., Davies, E. G., Schneider, D. T., Bernuth, H. V., Klingebiel, T., Hoffmann, G. F., Schulz, A. & Hauck, F., 07.2023, In: J CLIN IMMUNOL. 43, 5, p. 965-978 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MAP kinase activating death domain deficiency is a novel cause of impaired lymphocyte cytotoxicity
Schütze, K., Groß, M., Cornils, K., Wustrau, K., Schneppenheim, S., Lenhartz, H., Korenke, G-C., Janka, G., Ledig, S., Müller, I., Ehl, S. & Lehmberg, K., 25.04.2023, In: BLOOD ADV. 7, 8, p. 1531-1535 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism (FBP1, ACAD9) and vesicle trafficking (RAB27A)
Brauer, N., Maruta, Y., Lisci, M., Strege, K., Oschlies, I., Nakamura, H., Böhm, S., Lehmberg, K., Brandhoff, L., Ehl, S., Parvaneh, N., Klapper, W., Fukuda, M., Griffiths, G. M., Hennies, H. C., Niehues, T. & Ammann, S., 2023, In: FRONT IMMUNOL. 14, p. 1151166Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Essential medicines for childhood cancer in Europe: a pan-European, systematic analysis by SIOPE
Otth, M., Brack, E., Kearns, P. R., Kozhaeva, O., Ocokoljic, M., Schoot, R. A., Vassal, G. & Essential Medicines Group, 12.2022, In: LANCET ONCOL. 23, 12, p. 1537-1546 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Global effort to evacuate Ukrainian children with cancer and blood disorders who have been affected by war
Agulnik, A., Kizyma, R., Salek, M., Wlodarski, M. W., Pogorelyy, M., Oszer, A., Yakimkova, T., Nogovitsyna, Y., Dutkiewicz, M., Dalle, J-H., Dirksen, U., Eggert, A., Fernández-Teijeiro, A., Greiner, J., Kraal, K., Mueller, A., Sramkova, L., Zecca, M., Wise, P. H., Mlynarski, W. & SAFER Ukraine Collaborative, 09.2022, In: LANCET HAEMATOL. 9, 9, p. e645-e647Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults
Hines, M. R., von Bahr Greenwood, T., Beutel, G., Beutel, K., Hays, J. A., Horne, A., Janka, G., Jordan, M. B., van Laar, J. A. M., Lachmann, G., Lehmberg, K., Machowicz, R., Miettunen, P., La Rosée, P., Shakoory, B., Zinter, M. S. & Henter, J-I., 01.05.2022, In: CRIT CARE MED. 50, 5, p. 860-872 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Allogeneic hematopoietic stem cell transplantation for adult HLH: a retrospective study by the chronic malignancies and inborn errors working parties of EBMT
Machowicz, R., Suarez, F., Wiktor-Jedrzejczak, W., Eikema, D-J., de Wreede, L. C., Blok, H-J., Isaksson, C., Einsele, H., Poiré, X., van Dorp, S., Nikolousis, E., Johansson, J-E., Kobbe, G., Zecca, M., Arnold, R., Gerbitz, A., Finke, J., Díez-Martín, J. L., Bonifazi, F., McQuaker, G., Lenhoff, S., Rohrlich, P-S., Theobald, M., Ljungman, P., Collin, M., Albert, M. H., Ehninger, G., Carlson, K., Halaburda, K., Lehmberg, K., Schönland, S., Yakoub-Agha, I., Gennery, A. R., Lankester, A. C. & Kröger, N., 05.2022, In: BONE MARROW TRANSPL. 57, 5, p. 817-823 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD
Arnold, D. E., Nofal, R., Wakefield, C., Lehmberg, K., Wustrau, K., Albert, M. H., Morris, E. C., Heimall, J. R., Bunin, N. J., Kumar, A., Jordan, M. B., Cole, T., Choo, S., Brettig, T., Speckmann, C., Ehl, S., Salamonowicz, M., Wahlstrom, J., Rao, K., Booth, C., Worth, A. & Marsh, R. A., 01.2022, In: J CLIN IMMUNOL. 42, 1, p. 36-45 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity
Groß, M., Speckmann, C., May, A., Gajardo-Carrasco, T., Wustrau, K., Maier, S. L., Panning, M., Huzly, D., Agaimy, A., Bryceson, Y. T., Choo, S., Chow, C. W., Dückers, G., Fasth, A., Fraitag, S., Gräwe, K., Haxelmans, S., Holzinger, D., Hudowenz, O., Hübschen, J. M., Khurana, C., Kienle, K., Klifa, R., Korn, K., Kutzner, H., Lämmermann, T., Ledig, S., Lipsker, D., Meeths, M., Naumann-Bartsch, N., Rascon, J., Schänzer, A., Seidl, M., Tesi, B., Vauloup-Fellous, C., Vollmer-Kary, B., Warnatz, K., Wehr, C., Neven, B., Vargas, P., Sepulveda, F. E., Lehmberg, K., Schmitt-Graeff, A. & Ehl, S., 01.2022, In: J ALLERGY CLIN IMMUN. 149, 1, p. 388-399.e4Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations
Thalhammer, J., Kindle, G., Nieters, A., Rusch, S., Seppänen, M. R. J., Fischer, A., Grimbacher, B., Edgar, D., Buckland, M., Mahlaoui, N., Ehl, S. & European Society for Immunodeficiencies Registry Working Party, 11.2021, In: J ALLERGY CLIN IMMUN. 148, 5, p. 1332-1341.e5 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia
Zielen, S., Duecker, R. P., Woelke, S., Donath, H., Bakhtiar, S., Buecker, A., Kreyenberg, H., Huenecke, S., Bader, P., Mahlaoui, N., Ehl, S., El-Helou, S. M., Pietrucha, B., Plebani, A., van der Flier, M., van Aerde, K., Kilic, S. S., Reda, S. M., Kostyuchenko, L., McDermott, E., Galal, N., Pignata, C., Pérez, J. L. S., Laws, H-J., Niehues, T., Kutukculer, N., Seidel, M. G., Marques, L., Ciznar, P., Edgar, J. D. M., Soler-Palacín, P., von Bernuth, H., Krueger, R., Meyts, I., Baumann, U., Kanariou, M., Grimbacher, B., Hauck, F., Graf, D., Granado, L. I. G., Prader, S., Reisli, I., Slatter, M., Rodríguez-Gallego, C., Arkwright, P. D., Bethune, C., Deripapa, E., Sharapova, S. O., Lehmberg, K., Davies, E. G., Schuetz, C., Kindle, G. & Schubert, R., 11.2021, In: J CLIN IMMUNOL. 41, 8, p. 1878-1892 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary haemophagocytic lymphohistiocytosis (Chédiak-Higashi Syndrome) triggered by acute SARS-CoV-2 infection in a six-week-old infant
Lange, M., Linden, T., Müller, H. L., Flasskuehler, M. A., Koester, H., Lehmberg, K., Ledig, S., Ehl, S., Heep, A. & Beske, F., 10.2021, In: BRIT J HAEMATOL. 195, 2, p. 198-200 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
HSCT is effective in patients with PSTPIP1-associated myeloid-related proteinemia inflammatory (PAMI) syndrome
Laberko, A., Burlakov, V., Maier, S., Abinun, M., Skinner, R., Kozlova, A., Suri, D., Lehmberg, K., Müller, I., Balashov, D., Novichkova, G., Holzinger, D., Gennery, A. R. & Shcherbina, A., 07.2021, In: J ALLERGY CLIN IMMUN. 148, 1, p. 250-255.e1Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Is neutralization of IFN-γ sufficient to control inflammation in HLH?
Ehl, S., von Bahr Greenwood, T., Bergsten, E., Fischer, A., Henter, J-I., Hines, M., Lehmberg, K., Janka, G., Moshous, D. & Nichols, K. E., 03.2021, In: PEDIATR BLOOD CANCER. 68, 3, p. e28886Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Case Report: Hemophagocytic Lymphohistiocytosis and Non-Tuberculous Mycobacteriosis Caused by a Novel GATA2 Variant
Mika, T., Vangala, D., Eckhardt, M., La Rosée, P., Lange, C., Lehmberg, K., Wohlschläger, C., Biskup, S., Fuchs, I., Mann, J., Ehl, S., Warnatz, K. & Schroers, R., 2021, In: FRONT IMMUNOL. 12, 682934.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chronisch-rezidivierende Gonarthritis und Autoimmunneutropenie
Fröhlich, A., Lehmberg, K., Pagel, J., Peldschus, K., Schoof, B., Schulze-Sturm, U. & Speth, F., 2021, In: arthritis + rheuma. 41, 6, p. 387-392 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Risk factors for mixed chimerism in children with hemophagocytic lymphohistiocytosis after reduced toxicity conditioning
Wustrau, K., Greil, J., Sykora, K-W., Albert, M. H., Burkhardt, B., Lang, P., Meisel, R., Wössmann, W., Beier, R., Schulz, A., Bader, P., Chada, M., Kühl, J-S., Schlegel, P-G., Speckmann, C., Gruhn, B., Seidel, M., Wawer, A., Ozga, A-K., Janka, G., Ehl, S., Müller, I. & Lehmberg, K., 09.2020, In: PEDIATR BLOOD CANCER. 67, 9, p. e28523Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stem cell transplantation for children with hemophagocytic lymphohistiocytosis: results from the HLH-2004 study
Bergsten, E., Horne, A., Hed Myrberg, I., Aricó, M., Astigarraga, I., Ishii, E., Janka, G., Ladisch, S., Lehmberg, K., McClain, K. L., Minkov, M., Nanduri, V., Rosso, D. A., Sieni, E., Winiarski, J. & Henter, J-I., 11.08.2020, In: BLOOD ADV. 4, 15, p. 3754-3766 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neuroinflammatory Disease as an Isolated Manifestation of Hemophagocytic Lymphohistiocytosis
Blincoe, A., Heeg, M., Campbell, P. K., Hines, M., Khojah, A., Klein-Gitelman, M., Talano, J-A., Speckmann, C., Touzot, F., Lankester, A., Legger, G. E., Rivière, J. G., Garcia-Prat, M., Alonso, L., Putti, M. C., Lehmberg, K., Maier, S., El Chazli, Y., Elmaksoud, M. A., Astigarraga, I., Kurjane, N., Bulina, I., Kenina, V., Bryceson, Y., Rascon, J., Lortie, A., Goldstein, G., Booth, C., Worth, A., Wassmer, E., Schmitt, E. G., Warren, J. T., Bednarski, J. J., Ali, S., Chiang, K-Y., Krueger, J., Henry, M. M., Holland, S. M., Marsh, R. A., Ehl, S. & Haddad, E., 08.2020, In: J CLIN IMMUNOL. 40, 6, p. 901-916 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Incidence of SCID in Germany from 2014 to 2015 an ESPED* Survey on Behalf of the API*** Erhebungseinheit für Seltene Pädiatrische Erkrankungen in Deutschland (German Paediatric Surveillance Unit) ** Arbeitsgemeinschaft Pädiatrische Immunologie
Shai, S., Perez-Becker, R., Andres, O., Bakhtiar, S., Bauman, U., von Bernuth, H., Classen, C-F., Dückers, G., El-Helou, S. M., Gangfuß, A., Ghosh, S., Grimbacher, B., Hauck, F., Hoenig, M., Husain, R. A., Kindle, G., Kipfmueller, F., Klemann, C., Krüger, R., Lainka, E., Lehmberg, K., Lohrmann, F., Morbach, H., Naumann-Bartsch, N., Oommen, P. T., Schulz, A., Seidemann, K., Speckmann, C., Sykora, K-W., von Kries, R. & Niehues, T., 07.2020, In: J CLIN IMMUNOL. 40, 5, p. 708-717 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeted busulfan-based reduced-intensity conditioning and HLA-matched HSCT cure hemophagocytic lymphohistiocytosis
Felber, M., Steward, C. G., Kentouche, K., Fasth, A., Wynn, R. F., Zeilhofer, U., Haunerdinger, V., Volkmer, B., Prader, S., Gruhn, B., Ehl, S., Lehmberg, K., Müller, D., Gennery, A. R., Albert, M. H., Hauck, F., Rao, K., Veys, P., Hassan, M., Lankester, A. C., Schmid, J. P., Hauri-Hohl, M. M. & Güngör, T., 12.05.2020, In: BLOOD ADV. 4, 9, p. 1998-2010 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hemophagocytic lymphohistiocytosis in adults: collaborative analysis of 137 cases of a nationwide German registry
Birndt, S., Schenk, T., Heinevetter, B., Brunkhorst, F. M., Maschmeyer, G., Rothmann, F., Weber, T., Müller, M., Panse, J., Penack, O., Schroers, R., Braess, J., Frickhofen, N., Ehl, S., Janka, G., Lehmberg, K., Pletz, M. W., Hochhaus, A., Ernst, T. & La Rosée, P., 04.2020, In: J CANCER RES CLIN. 146, 4, p. 1065-1077 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ulceration in Prolidase Deficiency: Successful Treatment with Anticoagulants
Süßmuth, K., Metze, D., Muresan, A-M., Lehmberg, K., Zur Stadt, U., Speckmann, C., Park, J. H., Marquardt, T., Oji, V. & Goerge, T., 07.01.2020, In: ACTA DERM-VENEREOL. 100, 1, p. adv00002Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distinct molecular response patterns of activating STAT3 mutations associate with penetrance of lymphoproliferation and autoimmunity
Jägle, S., Heeg, M., Grün, S., Rensing-Ehl, A., Maccari, M. E., Klemann, C., Jones, N., Lehmberg, K., Bettoni, C., Warnatz, K., Grimbacher, B., Biebl, A., Schauer, U., Hague, R., Neth, O., Mauracher, A., Pachlopnik Schmid, J., Fabre, A., Kostyuchenko, L., Führer, M., Lorenz, M. R., Schwarz, K., Rohr, J. & Ehl, S., 01.2020, In: CLIN IMMUNOL. 210, p. 108316Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional flow cytometry of monocytes for routine diagnosis of innate primary immunodeficiencies
Ammann, S., Fuchs, S., Martin-Martin, L., Castro, C. N., Spielberger, B., Klemann, C., Elling, R., Heeg, M., Speckmann, C., Hainmann, I., Kaiser-Labusch, P., Horneff, G., Thalhammer, J., Bredius, R. G., Stadt, U. Z., Lehmberg, K., Fuchs, I., von Spee-Mayer, C., Henneke, P. & Ehl, S., 01.2020, In: J ALLERGY CLIN IMMUN. 145, 1, p. 434-437.e4Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Cell Versus Cytokine - Directed Therapies for Hemophagocytic Lymphohistiocytosis (HLH) in Inborn Errors of Immunity
Wegehaupt, O., Wustrau, K., Lehmberg, K. & Ehl, S., 2020, In: FRONT IMMUNOL. 11, 808.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Tuberculosis-Associated HLH in an 8-Month-Old Infant: A Case Report and Review
Hauch, H., Skrzypek, S., Woessmann, W., Lehmberg, K., Ehl, S., Speckmann, C., Schneck, E., Koerholz, D., Jux, C. & Neuhäuser, C., 2020, In: FRONT PEDIATR. 8, 556155.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Zinkmangel als Ursache eines „Dekubitus“ beim Frühgeborenen?
Asselborn, J. R., Thayssen, M., Lehmberg, K., Apostolidou, S. & Singer, D., 12.2019, In: Z GEBURTSH NEONATOL. 223, 6, p. 369-372 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A multicenter study of patients with multisystem Langerhans cell histiocytosis who develop secondary hemophagocytic lymphohistiocytosis
Chellapandian, D., Hines, M. R., Zhang, R., Jeng, M., van den Bos, C., Santa-María López, V., Lehmberg, K., Sieni, E., Wang, Y., Nakano, T., Williams, J. A., Fustino, N. J., Astigarraga, I., Dunkel, I. J., Abla, O., van Halteren, A. G. S., Pei, D., Cheng, C., Weitzman, S., Sung, L. & Nichols, K. E., 15.03.2019, In: CANCER-AM CANCER SOC. 125, 6, p. 963-971 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Haematopoietic Stem Cell Transplantation for Primary Haemophagocytic Lymphohistiocytosis
Lehmberg, K., Moshous, D. & Booth, C., 2019, In: FRONT PEDIATR. 7, p. 435Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Risikofaktoren für einen gemischten Chimerismus nach Stammzelltransplantation mit Treosulfan- oder Melphalanbasierter Konditionierung bei Kindern und Jugendlichen mit primärer Hämophagozytischer Lymphohistiozytose
Wustrau, K., Albert, M. H., Bader, P., Beier, R., Burkhardt, B., Chada, M., Greil, J., Gruhn, B., Kühl, J-S., Lang, P., Meisel, R., Schulz, A., Seidel, M., Speckmann, C., Sykora, K-W., Wawer, A., Wößmann, W., Ozga, A-K., Janka-Schaub, G., Ehl, S., Müller, I. & Lehmberg, K., 2019, Monatsschrift Kinderheilkunde > Ausgabe 7/2018 : Abstracts der 91. Wissenschaftlichen Halbjahrestagung der Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH). Vol. 01.07.2018 | Abstracts | Ausgabe 7/2018 . p. 646-647Research output: SCORING: Contribution to book/anthology › Conference contribution - Published abstract for conference with selection process › Research › peer-review
The German National Registry of Primary Immunodeficiencies (2012-2017)
El-Helou, S. M., Biegner, A-K., Bode, S., Ehl, S. R., Heeg, M., Maccari, M. E., Ritterbusch, H., Speckmann, C., Rusch, S., Scheible, R., Warnatz, K., Atschekzei, F., Beider, R., Ernst, D., Gerschmann, S., Jablonka, A., Mielke, G., Schmidt, R. E., Schürmann, G., Sogkas, G., Baumann, U. H., Klemann, C., Viemann, D., von Bernuth, H., Krüger, R., Hanitsch, L. G., Scheibenbogen, C. M., Wittke, K., Albert, M. H., Eichinger, A., Hauck, F., Klein, C., Rack-Hoch, A., Sollinger, F. M., Avila, A., Borte, M., Borte, S., Fasshauer, M., Hauenherm, A., Kellner, N., Müller, A. H., Ülzen, A., Bader, P., Bakhtiar, S., Lee, J-Y., Heß, U., Schubert, R., Wölke, S., Zielen, S., Ghosh, S., Laws, H-J., Neubert, J., Oommen, P. T., Hönig, M., Schulz, A., Steinmann, S., Schwarz, K., Dückers, G., Lamers, B., Langemeyer, V., Niehues, T., Shai, S., Graf, D., Müglich, C., Schmalzing, M. T., Schwaneck, E. C., Tony, H-P., Dirks, J., Haase, G., Liese, J. G., Morbach, H., Foell, D., Hellige, A., Wittkowski, H., Masjosthusmann, K., Geberzahn, L., Hedrich, C. M., Müller, C., Rösen-Wolff, A., Roesler, J., Zimmermann, A., Behrends, U., Rieber, N., Schauer, U., Handgretinger, R., Holzer, U., Henes, J., Kanz, L., Boesecke, C., Rockstroh, J. K., Schwarze-Zander, C., Wasmuth, J-C., Dilloo, D., Hülsmann, B., Schönberger, S., Schreiber, S., Zeuner, R., Ankermann, T., von Bismarck, P., Huppertz, H-I., Kaiser-Labusch, P., Greil, J., Jakoby, D., Kulozik, A. E., Metzler, M., Naumann-Bartsch, N., Sobik, B., Graf, N., Heine, S., Kobbe, R., Lehmberg, K., Müller, I., Herrmann, F., Horneff, G., Klein, A., Peitz, J., Schmidt, N., Bielack, S., Groß-Wieltsch, U., Classen, C. F., Klasen, J., Deutz, P., Kamitz, D., Lassay, L., Tenbrock, K., Wagner, N., Bernbeck, B., Brummel, B., Lara-Villacanas, E., Münstermann, E., Schneider, D. T., Tietsch, N., Westkemper, M., Weiß, M., Kramm, C., Kühnle, I., Kullmann, S., Girschick, H., Specker, C., Vinnemeier-Laubenthal, E., Haenicke, H., Schweigerer, L., Müller, T. G., Stiefel, M., Belohradsky, B. H., Soetedjo, V., Kindle, G. & Grimbacher, B., 2019, In: FRONT IMMUNOL. 10, p. 1272Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface
Moghaddas, F., Zeng, P., Zhang, Y., Schützle, H., Brenner, S., Hofmann, S. R., Berner, R., Zhao, Y., Lu, B., Chen, X., Zhang, L., Cheng, S., Winkler, S., Lehmberg, K., Canna, S. W., Czabotar, P. E., Wicks, I. P., De Nardo, D., Hedrich, C. M., Zeng, H. & Masters, S. L., 12.2018, In: J ALLERGY CLIN IMMUN. 142, 6, p. 1956-1967.e6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis
Lucchini, G., Marsh, R., Gilmour, K., Worth, A., Nademi, Z., Rao, A., Booth, C., Amrolia, P., Silva, J., Chiesa, R., Wynn, R., Lehmberg, K., Astigarraga, I., Güngör, T., Stary, J., Moshous, D., Ifversen, M., Zinn, D., Jordan, M., Kumar, A., Yasumi, T., Veys, P. & Rao, K., 08.11.2018, In: BLOOD. 132, 19, p. 2088-2096 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neuroimaging findings in children with hereditary hemophagocytic lymphohistiocytosis – report from the German reference center
Löbel, U., Wustrau, K., Müller, I., Janka-Schaub, G., Fiehler, J. & Lehmberg, K., 03.10.2018, NeuroRAD 2018 - 53. Jahrestagung der Deutschen Gesellschaft für Neuroradiologe e.V..Research output: SCORING: Contribution to book/anthology › Conference contribution - Poster › Research
Risk factors for mixed chimerism after stem cell transplantation with treosulfan or melphalan based conditioning regimens in children and adolescents with primary hemophagocytic lymphohistocytosis
Wustrau, K., Albert, M. H., Bader, P., Beier, R., Burkhardt, B., Chada, M., Greil, J., Gruhn, B., Kühl, J-S., Lang, P., Meisel, R., Schulz, A., Seidel, M., Speckmann, C., Sykora, K-W., Wawer, A., Wößmann, W., Ozga, A-K., Ehl, S., Müller, I. & Lehmberg, K., 24.09.2018, Bone Marrow Transplantation (2018) Abstracts Collection: The 44th Annual Meeting of the European Society for Blood and Marrow Transplantation:Physicians Oral Session.Research output: SCORING: Contribution to book/anthology › Conference contribution - Published abstract for conference with selection process › Research › peer-review
Recommendations for the Use of Etoposide-Based Therapy and Bone Marrow Transplantation for the Treatment of HLH: Consensus Statements by the HLH Steering Committee of the Histiocyte Society
Ehl, S., Astigarraga, I., von Bahr Greenwood, T., Hines, M., Horne, A., Ishii, E., Janka, G., Jordan, M. B., La Rosée, P., Lehmberg, K., Machowicz, R., Nichols, K. E., Sieni, E., Wang, Z. & Henter, J-I., 12.09.2018, In: J ALLER CL IMM-PRACT. 6, 5, p. 1508-1517 10 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
T-cell gene therapy for perforin deficiency corrects cytotoxicity defects and prevents hemophagocytic lymphohistiocytosis manifestations
Ghosh, S., Carmo, M., Calero-Garcia, M., Ricciardelli, I., Bustamante Ogando, J. C., Blundell, M. P., Schambach, A., Ashton-Rickardt, P. G., Booth, C., Ehl, S., Lehmberg, K., Thrasher, A. J. & Gaspar, H. B., 09.2018, In: J ALLERGY CLIN IMMUN. 142, 3, p. 904-913Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Is an infectious trigger always required for primary hemophagocytic lymphohistiocytosis? Lessons from in utero and neonatal disease
Heeg, M., Ammann, S., Klemann, C., Panning, M., Falcone, V., Hengel, H., Lehmberg, K., Zur Stadt, U., Wustrau, K., Janka, G. & Ehl, S., 01.08.2018, In: PEDIATR BLOOD CANCER. 65, 11, p. e27344Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hämophagozytische Lymphohistiozytose
Lehmberg, K., 2018, Referenz Hämatologie. Kreuzer, K-A. (ed.). Georg Thieme Verlag KGResearch output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Histiozytäre Erkrankungen
Lehmberg, K., 2018, Pädiatrische Hämatologie und Onkologie. Niemeyer, C. & Eggert, A. (eds.). 2 ed. Springer, (Springer Reference Medizin).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2017
Confirmed efficacy of etoposide and dexamethasone in HLH Treatment: long-term results of the cooperative HLH-2004 study
Bergsten, E., Horne, A., Aricó, M., Astigarraga, I., Egeler, R. M., Filipovich, A. H., Ishii, E., Janka, G., Ladisch, S., Lehmberg, K., McClain, K. L., Minkov, M., Montgomery, S., Nanduri, V., Rosso, D. & Henter, J-I., 21.12.2017, In: BLOOD. 130, 25, p. 2728-2738 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hemophagocytic lymphohistiocytosis as presenting manifestation of profound combined immunodeficiency due to an ORAI1 mutation
Klemann, C., Ammann, S., Heizmann, M., Fuchs, S., Bode, S. F., Heeg, M., Fuchs, H., Lehmberg, K., Zur Stadt, U., Roll, C., Vraetz, T., Speckmann, C., Lorenz, M. R., Schwarz, K., Rohr, J., Feske, S. & Ehl, S., 12.2017, In: J ALLERGY CLIN IMMUN. 140, 6, p. 1721-1724 4 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Effective Immunological Guidance of Genetic Analyses Including Exome Sequencing in Patients Evaluated for Hemophagocytic Lymphohistiocytosis
Ammann, S., Lehmberg, K., Zur Stadt, U., Klemann, C., Bode, S. F. N., Speckmann, C., Janka, G., Wustrau, K., Rakhmanov, M., Fuchs, I., Hennies, H. C., Ehl, S. & HLH study of the GPOH, 11.2017, In: J CLIN IMMUNOL. 37, 8, p. 770-780 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Development and Initial Validation of the Macrophage Activation Syndrome/Primary Hemophagocytic Lymphohistiocytosis Score, a Diagnostic Tool that Differentiates Primary Hemophagocytic Lymphohistiocytosis from Macrophage Activation Syndrome
Minoia, F., Bovis, F., Davì, S., Insalaco, A., Lehmberg, K., Shenoi, S., Weitzman, S., Espada, G., Gao, Y-J., Anton, J., Kitoh, T., Kasapcopur, O., Sanner, H., Merino, R., Astigarraga, I., Alessio, M., Jeng, M., Chasnyk, V., Nichols, K. E., Huasong, Z., Li, C., Micalizzi, C., Ruperto, N., Martini, A., Cron, R. Q., Ravelli, A., Horne, A. & Pediatric Rheumatology International Trials Organization, the Childhood Arthritis and Rheumatology Research Alliance, the Pediatric Rheumatology Collaborative Study Group, and the Histiocyte Society, 10.2017, In: J PEDIATR-US. 189, p. 72-78.e3Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evolution of disease activity and biomarkers on and off rapamycin in 28 patients with autoimmune lymphoproliferative syndrome
Klemann, C., Esquivel, M., Magerus-Chatinet, A., Lorenz, M. R., Fuchs, I., Neveux, N., Castelle, M., Rohr, J., Bettoni da Cunha, C., Ebinger, M., Kobbe, R., Kremens, B., Kollert, F., Gambineri, E., Lehmberg, K., Seidel, M. G., Siepermann, K., Voelker, T., Schuster, V., Goldacker, S., Schwarz, K., Speckmann, C., Picard, C., Fischer, A., Rieux-Laucat, F., Ehl, S., Rensing-Ehl, A. & Neven, B., 02.2017, In: HAEMATOLOGICA. 102, 2, p. e52-e56Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Inherited Thrombotic Thrombocytopenic Purpura (Upshaw Schulman Syndrome) as Differential Diagnosis to Neonatal Septicaemia with Disseminated Intravascular Coagulation - a Case Series
Lehmberg, K., Hassenpflug, W. A., Klaassen, I., Hillebrand, G., Oyen, F., Budde, U., Singer, D. & Schneppenheim, R., 02.2017, In: Z GEBURTSH NEONATOL. 221, 1, p. 39-42Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutations in EXTL3 Cause Neuro-immuno-skeletal Dysplasia Syndrome
Oud, M. M., Tuijnenburg, P., Hempel, M., van Vlies, N., Ren, Z., Ferdinandusse, S., Jansen, M. H., Santer, R., Johannsen, J., Bacchelli, C., Alders, M., Li, R., Davies, R., Dupuis, L., Cale, C. M., Wanders, R. J. A., Pals, S. T., Ocaka, L., James, C., Müller, I., Lehmberg, K., Strom, T., Engels, H., Williams, H. J., Beales, P., Roepman, R., Dias, P., Brunner, H. G., Cobben, J-M., Hall, C., Hartley, T., Le Quesne Stabej, P., Mendoza-Londono, R., Davies, E. G., de Sousa, S. B., Lessel, D., Arts, H. H. & Kuijpers, T. W., 02.2017, In: AM J HUM GENET. 100, 2, p. 281-296Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary and secondary hemophagocytic lymphohistiocytosis have different patterns of T-cell activation, differentiation and repertoire
Ammann, S., Lehmberg, K., Zur Stadt, U., Janka-Schaub, G., Rensing-Ehl, A., Klemann, C., Heeg, M., Bode, S., Fuchs, I., Ehl, S. & HLH study of the GPOH, 02.2017, In: EUR J IMMUNOL. 47, 2, p. 364-373Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review