PD Dr. med. ID: 31648
Henning Wege
Publications
- 2024
Characteristics and outcomes of immunotherapy-related liver injury in patients with hepatocellular carcinoma versus other advanced solid tumours
Celsa, C., Cabibbo, G., Am Fulgenzi, C., Scheiner, B., Antonio d'Alessio, Manfredi, G. F., Nishida, N., Ang, C., Marron, T. U., Saeed, A., Wietharn, B., Pinter, M., Cheon, J., Huang, Y-H., Lee, P-C., Phen, S., Gampa, A., Pillai, A., Vivaldi, C., Salani, F., Masi, G., Roehlen, N., Thimme, R., Vogel, A., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Galle, P. R., Kudo, M., Rimassa, L., Singal, A. G., El Tomb, P., Ulahannan, S., Parisi, A., Chon, H. J., Hsu, W-F., Stefanini, B., Verzoni, E., Giusti, R., Veccia, A., Catino, A., Aprile, G., Guglielmini, P. F., Di Napoli, M., Ermacora, P., Antonuzzo, L., Rossi, E., Verderame, F., Zustovich, F., Ficorella, C., Di Pietro, F. R., Battelli, N., Negrini, G., Grossi, F., Bordonaro, R., Pipitone, S., Banzi, M., Ricciardi, S., Laera, L., Russo, A., De Giorgi, U., Cavanna, L., Sorarù, M., Montesarchio, V., Bordi, P., Brunetti, L., Pinto, C., Bersanelli, M., Cammà, C., Cortellini, A. & Pinato, D. J., 03.2024, In: J HEPATOL. 80, 3, p. 431-442 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A meta-analysis and real-world cohort study on the sex-related differences in efficacy and safety of immunotherapy for hepatocellular carcinoma
Balcar, L., Scheiner, B., Fulgenzi, C. A. M., D'Alessio, A., Pomej, K., Roig, M. B., Meyer, E. L., Che, J., Nishida, N., Lee, P-C., Wu, L., Ang, C., Krall, A., Saeed, A., Stefanini, B., Cammarota, A., Pressiani, T., Abugabal, Y. I., Chamseddine, S., Wietharn, B., Parisi, A., Huang, Y-H., Phen, S., Vivaldi, C., Salani, F., Masi, G., Bettinger, D., Vogel, A., von Felden, J., Schulze, K., Silletta, M., Trauner, M., Samson, A., Wege, H., Piscaglia, F., Galle, P. R., Stauber, R., Kudo, M., Singal, A. G., Itani, A., Ulahannan, S. V., Parikh, N. D., Cortellini, A., Kaseb, A., Rimassa, L., Chon, H. J., Pinato, D. J. & Pinter, M., 02.2024, In: JHEP REP. 6, 2, p. 100982Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
EpCAM-positive circulating tumor cells and serum AFP levels predict outcome after curative resection of hepatocellular carcinoma
Kocheise, L., Schoenlein, M., Behrends, B., Joerg, V., Casar, C., Fründt, T. W., Renné, T., Heumann, A., Li, J., Huber, S., Lohse, A. W., Pantel, K., Riethdorf, S., Wege, H., Schulze, K. & von Felden, J., 27.11.2023, In: SCI REP-UK. 13, 1, p. 20827Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficacy and safety of atezolizumab/bevacizumab in patients with HCC after prior systemic therapy: A global, observational study
Joerg, V., Scheiner, B., D Alessio, A., Fulgenzi, C. A. M., Schönlein, M., Kocheise, L., Lohse, A. W., Huber, S., Wege, H., Kaseb, A., Wang, Y., Mathew, A., Kuang, A., Muzaffar, M., Abugabal, Y. I., Chamseddine, S., Phen, S., Cheon, J., Lee, P-C., Balcar, L., Krall, A., Ang, C., Wu, L., Saeed, A., Huang, Y-H., Bengsch, B., Rimassa, L., Weinmann, A., Stauber, R., Korolewicz, J., Pinter, M., Singal, A. G., Chon, H. J., Pinato, D. J., Schulze, K. & von Felden, J., 01.11.2023, In: HEPATOL COMMUN. 7, 11, e0302.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of body mass index in patients receiving atezolizumab plus bevacizumab for hepatocellular carcinoma
Vithayathil, M., D'Alessio, A., Fulgenzi, C. A. M., Nishida, N., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Saeed, A., Wietharn, B., Hildebrand, H., Wu, L., Ang, C., Marron, T. U., Weinmann, A., Galle, P. R., Bettinger, D., Bengsch, B., Vogel, A., Balcar, L., Scheiner, B., Lee, P-C., Huang, Y-H., Amara, S., Muzaffar, M., Naqash, A. R., Cammarota, A., Zanuso, V., Pressiani, T., Pinter, M., Cortellini, A., Kudo, M., Rimassa, L., Pinato, D. J. & Sharma, R., 08.2023, In: HEPATOL INT. 17, 4, p. 904-914 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
S3-Leitlinie Diagnostik und Therapie biliärer Karzinome: Kurzversion
Bitzer, M., Groß, S., Albert, J., Boda-Heggemann, J., Brunner, T., Caspari, R., De Toni, E., Dombrowski, F., Evert, M., Geier, A., Gkika, E., Götz, M., Helmberger, T., Hoffmann, R-T., Huppert, P., Kautz, A., Krug, D., Fougère, C. L., Lang, H., Lenz, P., Lüdde, T., Mahnken, A., Nadalin, S., Nguyen, H. H. P., Ockenga, J., Oldhafer, K., Paprottka, P., Pereira, P., Persigehl, T., Plentz, R., Pohl, J., Recken, H., Reimer, P., Riemer, J., Ritterbusch, U., Roeb, E., Rüssel, J., Schellhaas, B., Schirmacher, P., Schlitt, H. J., Schmid, I., Schuler, A., Seehofer, D., Sinn, M., Stengel, A., Stoll, C., Tannapfel, A., Taubert, A., Tholen, R., Trojan, J., van Thiel, I., Vogel, A., Vogl, T., Wacker, F., Waidmann, O., Wedemeyer, H., Wege, H., Wildner, D., Wörns, M-A., Galle, P. & Malek, N., 04.2023, In: Z GASTROENTEROL. 61, 4, p. 420-440 21 p.Research output: SCORING: Contribution to journal › Guideline, recommendation, statement › Transfer
S3-Leitlinie Diagnostik und Therapie biliärer Karzinome – Langversion
Bitzer, M., Groß, S., Albert, J., Boda-Heggemann, J., Brunner, T., Caspari, R., De Toni, E., Dombrowski, F., Evert, M., Geier, A., Gkika, E., Götz, M., Helmberger, T., Hoffmann, R-T., Huppert, P., Kautz, A., Krug, D., Fougère, C. L., Lang, H., Lenz, P., Lüdde, T., Mahnken, A., Nadalin, S., Nguyen, H. H. P., Ockenga, J., Oldhafer, K., Paprottka, P., Pereira, P., Persigehl, T., Plentz, R., Pohl, J., Recken, H., Reimer, P., Riemer, J., Ritterbusch, U., Roeb, E., Rüssel, J., Schellhaas, B., Schirmacher, P., Schlitt, H. J., Schmid, I., Schuler, A., Seehofer, D., Sinn, M., Stengel, A., Stoll, C., Tannapfel, A., Taubert, A., Tholen, R., Trojan, J., van Thiel, I., Vogel, A., Vogl, T., Wacker, F., Waidmann, O., Wedemeyer, H., Wege, H., Wildner, D., Wörns, M-A., Galle, P. & Malek, N., 04.2023, In: Z GASTROENTEROL. 61, 4, p. e92-e156 65 p.Research output: SCORING: Contribution to journal › Guideline, recommendation, statement › Transfer
- 2022
Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios as Prognostic Biomarkers in Unresectable Hepatocellular Carcinoma Treated with Atezolizumab plus Bevacizumab
Wu, Y. L., Fulgenzi, C. A. M., D'Alessio, A., Cheon, J., Nishida, N., Saeed, A., Wietharn, B., Cammarota, A., Pressiani, T., Personeni, N., Pinter, M., Scheiner, B., Balcar, L., Huang, Y-H., Phen, S., Naqash, A. R., Vivaldi, C., Salani, F., Masi, G., Bettinger, D., Vogel, A., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Galle, P. R., Kudo, M., Rimassa, L., Singal, A. G., Sharma, R., Cortellini, A., Gaillard, V. E., Chon, H. J., Pinato, D. J. & Ang, C., 26.11.2022, In: CANCERS. 14, 23, 5834.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of older age in patients receiving atezolizumab and bevacizumab for hepatocellular carcinoma
Vithayathil, M., D'Alessio, A., Fulgenzi, C. A. M., Nishida, N., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Saeed, A., Wietharn, B., Hildebrand, H., Wu, L., Ang, C., Marron, T. U., Weinmann, A., Galle, P. R., Bettinger, D., Bengsch, B., Vogel, A., Balcar, L., Scheiner, B., Lee, P-C., Huang, Y-H., Amara, S., Muzaffar, M., Naqash, A. R., Cammarota, A., Personeni, N., Pressiani, T., Pinter, M., Cortellini, A., Kudo, M., Rimassa, L., Pinato, D. J. & Sharma, R., 11.2022, In: LIVER INT. 42, 11, p. 2538-2547 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study
Fulgenzi, C. A. M., Cheon, J., D'Alessio, A., Nishida, N., Ang, C., Marron, T. U., Wu, L., Saeed, A., Wietharn, B., Cammarota, A., Pressiani, T., Personeni, N., Pinter, M., Scheiner, B., Balcar, L., Napolitano, A., Huang, Y-H., Phen, S., Naqash, A. R., Vivaldi, C., Salani, F., Masi, G., Bettinger, D., Vogel, A., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Galle, P. R., Kudo, M., Rimassa, L., Singal, A. G., Sharma, R., Cortellini, A., Gaillard, V. E., Chon, H. J. & Pinato, D. J., 11.2022, In: EUR J CANCER. 175, p. 204-213 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Preliminary evidence of safety and tolerability of atezolizumab plus bevacizumab in patients with hepatocellular carcinoma and Child-Pugh A and B cirrhosis: a real-world study
D'Alessio, A., Fulgenzi, C. A. M., Nishida, N., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Gaillard, V. E., Saeed, A., Wietharn, B., Hildebrand, H., Wu, L., Ang, C., Marron, T. U., Weinmann, A., Galle, P. R., Bettinger, D., Bengsch, B., Vogel, A., Balcar, L., Scheiner, B., Lee, P-C., Huang, Y-H., Amara, S., Muzaffar, M., Naqash, A. R., Cammarota, A., Personeni, N., Pressiani, T., Sharma, R., Pinter, M., Cortellini, A., Kudo, M., Rimassa, L. & Pinato, D. J., 10.2022, In: HEPATOLOGY. 76, 4, p. 1000-1012 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Real-World Data for Lenvatinib in Hepatocellular Carcinoma (ELEVATOR): A Retrospective Multicenter Study
Welland, S., Leyh, C., Finkelmeier, F., Jefremow, A., Shmanko, K., Gonzalez-Carmona, M. A., Kandulski, A., Jeliazkova, P., Best, J., Fründt, T. W., Djanani, A., Pangerl, M., Maieron, A., Greil, R., Fricke, C., Sookthai, D., Günther, R., Schmiderer, A., Wege, H., Venerito, M., Ehmer, U., Müller, M., Strassburg, C. P., Weinmann, A., Siebler, J., Waidmann, O., Lange, C. M., Saborowski, A. & Vogel, A., 06.2022, In: LIVER CANCER. 11, 3, p. 219-232 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Atezolizumab and bevacizumab with transarterial chemoembolization in hepatocellular carcinoma: the DEMAND trial protocol
Khaled, N. B., Seidensticker, M., Ricke, J., Mayerle, J., Oehrle, B., Rössler, D., Teupser, D., Ehmer, U., Bitzer, M., Waldschmidt, D., Fuchs, M., Reuken, P. A., Lange, C. M., Wege, H., Kandulski, A., Dechêne, A., Venerito, M., Berres, M-L., Luedde, T., Kubisch, I., Reiter, F. P. & De Toni, E. N., 04.2022, In: FUTURE ONCOL. 18, 12, p. 1423-1435 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Equal Efficacy and Safety Profile in Elderly Patients with Hepatocellular Carcinoma Receiving Palliative Treatment
Fründt, T. W., Casar, C., von Felden, J., Schöler, U., Priebe, M., Kraczyk, J., Ahrend, H., Salamon, J., Adam, G., Huber, S., Lohse, A. W., Wege, H. & Schulze, K., 01.02.2022, In: CANCERS. 14, 3, 768.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Der Einsatz der immunonkologischen Therapie beim hepatozellulären Karzinom im Kontext der Lebertransplantation Eine interdisziplinäre Risiko-Nutzen-Abwägung
Vogel, A., Sterneck, M., Vondran, F., Waidmann, O., Klein, I., Lindig, U., Nadalin, S., Settmacher, U., Tacke, F., Schlitt, H. J. & Wege, H., 02.2022, In: Z GASTROENTEROL. 60, 2, p. 184-191 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Gallengangskrebs: Zu häufig eine zu späte Diagnose
Wege, H., 02.2022, In: MMW Fortschr Med. 164, Suppl 4, p. 19-21 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prognosis of patients with hepatocellular carcinoma treated with immunotherapy - development and validation of the CRAFITY score
Scheiner, B., Pomej, K., Kirstein, M. M., Hucke, F., Finkelmeier, F., Waidmann, O., Himmelsbach, V., Schulze, K., von Felden, J., Fründt, T. W., Stadler, M., Heinzl, H., Shmanko, K., Spahn, S., Radu, P., Siebenhüner, A. R., Mertens, J. C., Rahbari, N. N., Kütting, F., Waldschmidt, D-T., Ebert, M. P., Teufel, A., De Dosso, S., Pinato, D. J., Pressiani, T., Meischl, T., Balcar, L., Müller, C., Mandorfer, M., Reiberger, T., Trauner, M., Personeni, N., Rimassa, L., Bitzer, M., Trojan, J., Weinmann, A., Wege, H., Dufour, J-F., Peck-Radosavljevic, M., Vogel, A. & Pinter, M., 02.2022, In: J HEPATOL. 76, 2, p. 353-363 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
S3-Leitlinie: Diagnostik und Therapie biliärer Karzinome: Langversion 2.0 – Juni 2021 – AWMF-Registernummer: 032-053OL
Bitzer, M., Voesch, S., Albert, J., Bartenstein, P., Bechstein, W., Blödt, S., Brunner, T., Dombrowski, F., Evert, M., Follmann, M., La Fougère, C., Freudenberger, P., Geier, A., Gkika, E., Götz, M., Hammes, E., Helmberger, T., Hoffmann, R. T., Hofmann, W. P., Huppert, P., Kautz, A., Knötgen, G., Körber, J., Krug, D., Lammert, F., Lang, H., Langer, T., Lenz, P., Mahnken, A., Meining, A., Micke, O., Nadalin, S., Nguyen, H. P., Ockenga, J., Oldhafer, K., Paprottka, P., Paradies, K., Pereira, P., Persigehl, T., Plauth, M., Plentz, R., Pohl, J., Riemer, J., Reimer, P., Ringwald, J., Ritterbusch, U., Roeb, E., Schellhaas, B., Schirmacher, P., Schmid, I., Schuler, A., von Schweinitz, D., Seehofer, D., Sinn, M., Stein, A., Stengel, A., Steubesand, N., Stoll, C., Tannapfel, A., Taubert, A., Trojan, J., van Thiel, I., Tholen, R., Vogel, A., Vogl, T., Vorwerk, H., Wacker, F., Waidmann, O., Wedemeyer, H., Wege, H., Wildner, D., Wittekind, C., Wörns, M. A., Galle, P. & Malek, N., 02.2022, In: Z GASTROENTEROL. 60, 2, p. 219-238Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
S3-Leitlinie: Diagnostik und Therapie des hepatozellulären Karzinoms
Sabrina, V., Michael, B., Jörg, A., Peter, B., Wolf, B., Susanne, B., Thomas, B., Frank, D., Matthias, E., Markus, F., Christian, L. F., Paul, F., Andreas, G., Eleni, G., Martin, G., Elke, H., Thomas, H., Ralf-Thorsten, H., Wolf-Peter, H., Peter, H., Achim, K., Gabi, K., Jürgen, K., David, K., Frank, L., Hauke, L., Thomas, L., Philipp, L., Andreas, M., Alexander, M., Oliver, M., Silvio, N., Huu Phuc, N., Johann, O., Karl-Jürgen, O., Philipp, P., Kerstin, P., Philippe, P., Thorsten, P., Mathias, P., Ruben, P., Jürgen, P., Jutta, R., Peter, R., Johanna, R., Ulrike, R., Elke, R., Barbara, S., Peter, S., Irene, S., Andreas, S., Dietrich, V. S., Daniel, S., Marianne, S., Alexander, S., Andreas, S., Nadine, S., Christian, S., Andrea, T., Anne, T., Jörg, T., Ingo, V. T., Reina, T., Arndt, V., Thomas, V., Hilke, V., Frank, W., Oliver, W., Heiner, W., Henning, W., Dane, W., Christian, W., Marcus-Alexander, W., Peter, G. & Nisar, M., 01.2022, In: Z GASTROENTEROL. 60, 1, p. e56-e130Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
S3-Leitlinie: Diagnostik und Therapie des hepatozellulären Karzinoms – Kurzversion 2.00 – Juni 2021, AWMF-Registernummer: 032-053OL
Sabrina, V., Michael, B., Jörg, A., Peter, B., Wolf, B., Susanne, B., Thomas, B., Frank, D., Matthias, E., Markus, F., Christian, L. F., Paul, F., Andreas, G., Eleni, G., Martin, G., Elke, H., Thomas, H., Ralf-Thorsten, H., Wolf-Peter, H., Peter, H., Achim, K., Gabi, K., Jürgen, K., David, K., Frank, L., Hauke, L., Thomas, L., Philipp, L., Andreas, M., Alexander, M., Oliver, M., Silvio, N., Huu Phuc, N., Johann, O., Karl-Jürgen, O., Philipp, P., Kerstin, P., Philippe, P., Thorsten, P., Mathias, P., Ruben, P., Jürgen, P., Jutta, R., Peter, R., Johanna, R., Ulrike, R., Elke, R., Barbara, S., Peter, S., Irene, S., Andreas, S., Dietrich, V. S., Daniel, S., Marianne, S., Alexander, S., Andreas, S., Nadine, S., Christian, S., Andrea, T., Anne, T., Jörg, T., Ingo, V. T., Reina, T., Arndt, V., Thomas, V., Hilke, V., Frank, W., Oliver, W., Heiner, W., Henning, W., Dane, W., Christian, W., Marcus-Alexander, W., Peter, G. & Nisar, M., 01.2022, In: Z GASTROENTEROL. 60, 1, p. 81-107 27 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Circulating tumor cells as a preoperative risk marker for occult metastases in patients with resectable cholangiocarcinoma
Fründt, T., von Felden, J., Krause, J., Heumann, A., Li, J., Riethdorf, S., Pantel, K., Huber, S., Lohse, A. W., Wege, H. & Schulze, K., 2022, In: FRONT ONCOL. 12, 941660.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Rare variants of primary liver cancer: Fibrolamellar, combined, and sarcomatoid hepatocellular carcinomas
Wege, H., Schulze, K., von Felden, J., Calderaro, J., Reig, M. & European Reference Network on Hepatological Diseases (ERN RARE-LIVER), 01.11.2021, In: EUR J MED GENET. 64, 11, 104313.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Early Detection of Hepatocellular Carcinoma Since the Introduction of the German Clinical Practice Guideline in 2013
Schulze, K., Felden, J. V., Fründt, T. W., Krause, J., Werner, T., Casar, C., Jung, C., Ittrich, H., Sterneck, M., Li, J., Heumann, A., Fischer, L., Adam, G., Lohse, A. W. & Wege, H., 09.08.2021, In: DTSCH ARZTEBL INT. 118, 31-32, p. 540-541 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Cabozantinib in Advanced Hepatocellular Carcinoma: Efficacy and Safety Data from an International Multicenter Real-Life Cohort
Finkelmeier, F., Scheiner, B., Leyh, C., Best, J., Fründt, T. W., Czauderna, C., Beutel, A., Bettinger, D., Weiß, J., Meischl, T., Kütting, F., Waldschmidt, D-T., Radu, P., Schultheiß, M., Peiffer, K-H., Ettrich, T. J., Weinmann, A., Wege, H., Venerito, M., Dufour, J-F., Lange, C. M., Pinter, M. & Waidmann, O., 07.2021, In: LIVER CANCER. 10, 4, p. 360-369 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Assessing the impact of COVID-19 on liver cancer management (CERO-19)
Muñoz-Martínez, S., Sapena, V., Forner, A., Nault, J-C., Sapisochin, G., Rimassa, L., Sangro, B., Bruix, J., Sanduzzi-Zamparelli, M., Hołówko, W., El Kassas, M., Mocan, T., Bouattour, M., Merle, P., Hoogwater, F. J. H., Alqahtani, S. A., Reeves, H. L., Pinato, D. J., Giorgakis, E., Meyer, T., Villadsen, G. E., Wege, H., Salati, M., Mínguez, B., Di Costanzo, G. G., Roderburg, C., Tacke, F., Varela, M., Galle, P. R., Alvares-da-Silva, M. R., Trojan, J., Bridgewater, J., Cabibbo, G., Toso, C., Lachenmayer, A., Casadei-Gardini, A., Toyoda, H., Lüdde, T., Villani, R., Matilla Peña, A. M., Guedes Leal, C. R., Ronzoni, M., Delgado, M., Perelló, C., Pascual, S., Lledó, J. L., Argemi, J., Basu, B., da Fonseca, L., Acevedo, J., Siebenhüner, A. R., Braconi, C., Meyers, B. M., Granito, A., Sala, M., Rodríguez Lope, C., Blaise, L., Romero-Gómez, M., Piñero, F., Gomez, D., Mello, V., Pinheiro Alves, R. C., França, A., Branco, F., Brandi, G., Pereira, G., Coll, S., Guarino, M., Benítez, C., Anders, M. M., Bandi, J. C., Vergara, M., Calvo, M., Peck-Radosavljevic, M., García-Juárez, I., Cardinale, V., Lozano, M., Gambato, M., Okolicsanyi, S., Arraez, D. M., Elvevi, A., Muñoz, A. E., Lué, A., Iavarone, M. & Reig, M., 06.2021, In: JHEP REP. 3, 3, 100260.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diagnostic and Prognostic Value of miR-16, miR-146a, miR-192 and miR-221 in Exosomes of Hepatocellular Carcinoma and Liver Cirrhosis Patients
Fründt, T., Krause, L., Hussey, E., Steinbach, B., Köhler, D., von Felden, J., Schulze, K., Lohse, A. W., Wege, H. & Schwarzenbach, H., 19.05.2021, In: CANCERS. 13, 10, p. 2484Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
Pfister, D., Núñez, N. G., Pinyol, R., Govaere, O., Pinter, M., Szydlowska, M., Gupta, R., Qiu, M., Deczkowska, A., Weiner, A., Müller, F., Sinha, A., Friebel, E., Engleitner, T., Lenggenhager, D., Moncsek, A., Heide, D., Stirm, K., Kosla, J., Kotsiliti, E., Leone, V., Dudek, M., Yousuf, S., Inverso, D., Singh, I., Teijeiro, A., Castet, F., Montironi, C., Haber, P. K., Tiniakos, D., Bedossa, P., Cockell, S., Younes, R., Vacca, M., Marra, F., Schattenberg, J. M., Allison, M., Bugianesi, E., Ratziu, V., Pressiani, T., D'Alessio, A., Personeni, N., Rimassa, L., Daly, A. K., Scheiner, B., Pomej, K., Kirstein, M. M., Vogel, A., Peck-Radosavljevic, M., Hucke, F., Finkelmeier, F., Waidmann, O., Trojan, J., Schulze, K., Wege, H., Koch, S., Weinmann, A., Bueter, M., Rössler, F., Siebenhüner, A., De Dosso, S., Mallm, J-P., Umansky, V., Jugold, M., Luedde, T., Schietinger, A., Schirmacher, P., Emu, B., Augustin, H. G., Billeter, A., Müller-Stich, B., Kikuchi, H., Duda, D. G., Kütting, F., Waldschmidt, D-T., Ebert, M. P., Rahbari, N., Mei, H. E., Schulz, A. R., Ringelhan, M., Malek, N., Spahn, S., Bitzer, M., Ruiz de Galarreta, M., Lujambio, A., Dufour, J-F., Marron, T. U., Kaseb, A., Kudo, M., Huang, Y-H., Djouder, N., Wolter, K., Zender, L., Marche, P. N., Decaens, T., Pinato, D. J., Rad, R., Mertens, J. C., Weber, A., Unger, K., Meissner, F., Roth, S., Jilkova, Z. M., Claassen, M., Anstee, Q. M., Amit, I., Knolle, P., Becher, B., Llovet, J. M. & Heikenwalder, M., 04.2021, In: NATURE. 592, 7854, p. 450-456 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sequential Systemic Treatment in Advanced Hepatocellular Carcinoma Is Able to Prolong Median Survival to More than 3 Years in a Selected Real-World Cohort
von Felden, J., Karkmann, K., Ittrich, H., Gil-Ibanez, I., Fründt, T., Krause, J., Lohse, A. W., Wege, H. & Schulze, K., 03.2021, In: VISC MED. 37, 2, p. 87-93 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low incidence of COVID-19 in a prospective cohort of patients with liver cirrhosis and hepatocellular carcinoma treated at a tertiary medical center during the 2020 pandemic
Fründt, T., Kuballa, L., Lütgehetman, M., Nörz, D., Arend, H., Brehm, T. T., Schulze Zur Wiesch, J., Horvatits, T., Horvatits, K., Huber, S., Wege, H. & Kluwe, J., 2021, In: PLOS ONE. 16, 12, p. e0258450Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Hepatocellular carcinoma: Intratumoral EpCAM-positive cancer stem cell heterogeneity identifies high-risk tumor subtype
Krause, J., von Felden, J., Casar, C., Fründt, T. W., Galaski, J., Schmidt, C., Jung, C., Ittrich, H., Weidemann, S. A., Krech, T., Heumann, A., Li, J., Fischer, L., Sauter, G., Lohse, A. W., Wege, H. & Schulze, K., 23.11.2020, In: BMC CANCER. 20, 1, p. 1130Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Perforation of the ascending colon during implantation of an indwelling peritoneal catheter: a case report
Paparoupa, M., Wege, H., Creutzfeldt, A., Sebode, M., Uzunoglu, F. G., Boenisch, O., Nierhaus, A., Izbicki, J. R. & Kluge, S., 16.10.2020, In: BMC GASTROENTEROL. 20, 1, p. 345Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SOP Transarterielle Chemoembolisation zur Tumortherapie
Ittrich, H., Wege, H. & Schrader, J., 07.09.2020, In: Gastroenterologie up2date. 2020, 16, p. 201-208 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Elevated Aspartate Aminotransferase to Alanine Aminotransferase Ratio Predicts Poor Outcome in Hepatocellular Carcinoma
von Felden, J., Wege, H. & Schulze, K., 09.2020, In: HEPATOL COMMUN. 4, 9, p. 1382-1383 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Genetic variation in HSD17B13 reduces the risk of developing cirrhosis and hepatocellular carcinoma in alcohol misusers
Stickel, F., Lutz, P., Buch, S., Nischalke, H. D., Silva, I., Rausch, V., Fischer, J., Weiss, K. H., Gotthardt, D., Rosendahl, J., Marot, A., Elamly, M., Krawczyk, M., Casper, M., Lammert, F., Buckley, T. W., McQuillin, A., Spengler, U., Eyer, F., Vogel, A., Marhenke, S., von Felden, J., Wege, H., Sharma, R., Atkinson, S., Franke, A., Nehring, S., Moser, V., Schafmayer, C., Spahr, L., Lackner, C., Stauber, R. E., Canbay, A., Link, A., Valenti, L., Grove, J. I., Aithal, G. P., Marquardt, J. U., Fateen, W., Zopf, S., Dufour, J-F., Trebicka, J., Datz, C., Deltenre, P., Mueller, S., Berg, T., Hampe, J. & Morgan, M. Y., 07.2020, In: HEPATOLOGY. 72, 1, p. 88-102 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gallengangs- und Gallenblasenkarzinome: auf dem Weg zur personalisierten Therapie
Sinn, M., Wege, H. & Stein, A., 04.2020, In: DEUT MED WOCHENSCHR. 145, 7, p. 442-446 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
GALAD Score Detects Early Hepatocellular Carcinoma in an International Cohort of Patients With Nonalcoholic Steatohepatitis
Best, J., Bechmann, L. P., Sowa, J-P., Sydor, S., Dechêne, A., Pflanz, K., Bedreli, S., Schotten, C., Geier, A., Berg, T., Fischer, J., Vogel, A., Bantel, H., Weinmann, A., Schattenberg, J. M., Huber, Y., Wege, H., von Felden, J., Schulze, K., Bettinger, D., Thimme, R., Sinner, F., Schütte, K., Weiss, K. H., Toyoda, H., Yasuda, S., Kumada, T., Berhane, S., Wichert, M., Heider, D., Gerken, G., Johnson, P. & Canbay, A., 03.2020, In: CLIN GASTROENTEROL H. 18, 3, p. 728-735.e4Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
SOP Spontan bakterielle Peritonitis bei Leberzirrhose
Wege, H. & Kluwe, J., 12.2019, In: Gastroenterologie up2date. 2019, 15, p. 321-325 5 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Treatment Lines in Hepatocellular Carcinoma
Wege, H., Li, J. & Ittrich, H., 08.2019, In: VISC MED. 35, 4, p. 266-272 7 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Doxorubicin-loaded nanoparticles for patients with advanced hepatocellular carcinoma after sorafenib treatment failure (RELIVE): A phase 3 randomised controlled trial
Merle, P., Blanc, J-F., Phelip, J-M., Pelletier, G., Bronowicki, J-P., Touchefeu, Y., Pageaux, G., Gerolami, R., Habersetzer, F., Nguyen-Khac, E., Casadei-Gardini, A., Borbath, I., Tran, A., Wege, H., Saad, A. S., Colombo, M., Abergel, A., Richou, C., Waked, I., Yee, N. S., Molé, A., Attali, P., Le Boulicaut, J., Vasseur, B. & RELIVE Investigators, 06.2019, In: LANCET GASTROENTEROL. 4, 6, p. 454-465 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Programmed cell death protein-1 (PD-1)-targeted immunotherapy in advanced hepatocellular carcinoma: efficacy and safety data from an international multicentre real-world cohort
Scheiner, B., Kirstein, M. M., Hucke, F., Finkelmeier, F., Schulze, K., von Felden, J., Koch, S., Schwabl, P., Hinrichs, J. B., Waneck, F., Waidmann, O., Reiberger, T., Müller, C., Sieghart, W., Trauner, M., Weinmann, A., Wege, H., Trojan, J., Peck-Radosavljevic, M., Vogel, A. & Pinter, M., 05.2019, In: ALIMENT PHARM THER. 49, 10, p. 1323-1333 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Vaccinia-based oncolytic immunotherapy Pexastimogene Devacirepvec in patients with advanced hepatocellular carcinoma after sorafenib failure: a randomized multicenter Phase IIb trial (TRAVERSE)
Moehler, M., Heo, J., Lee, H. C., Tak, W. Y., Chao, Y., Paik, S. W., Yim, H. J., Byun, K. S., Baron, A., Ungerechts, G., Jonker, D., Ruo, L., Cho, M., Kaubisch, A., Wege, H., Merle, P., Ebert, O., Habersetzer, F., Blanc, J. F., Rosmorduc, O., Lencioni, R., Patt, R., Leen, A. M., Foerster, F., Homerin, M., Stojkowitz, N., Lusky, M., Limacher, J. M., Hennequi, M., Gaspar, N., McFadden, B., De Silva, N., Shen, D., Pelusio, A., Kirn, D. H., Breitbach, C. J. & Burke, J. M., 2019, In: ONCOIMMUNOLOGY. 8, 8, p. 1615817Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Fast and facile analysis of glycosylation and phosphorylation of fibrinogen from human plasma-correlation with liver cancer and liver cirrhosis
Nagel, T., Klaus, F., Ibanez, I. G., Wege, H., Lohse, A. & Meyer, B., 12.2018, In: ANAL BIOANAL CHEM. 410, 30, p. 7965-7977 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol-related cirrhosis
Stickel, F., Buch, S., Nischalke, H. D., Weiss, K. H., Gotthardt, D., Fischer, J., Rosendahl, J., Marot, A., Elamly, M., Casper, M., Lammert, F., McQuillin, A., Zopf, S., Spengler, U., Marhenke, S., Kirstein, M. M., Vogel, A., Eyer, F., von Felden, J., Wege, H., Buch, T., Schafmayer, C., Braun, F., Deltenre, P., Berg, T., Morgan, M. Y. & Hampe, J., 10.2018, In: AM J GASTROENTEROL. 113, 10, p. 1475-1483 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Correction: Genetic Variants in PNPLA3 and TM6SF2 Predispose to the Development of Hepatocellular Carcinoma in Individuals With Alcohol-Related Cirrhosis
Stickel, F., Buch, S., Nischalke, H. D., Weiss, K. H., Gotthardt, D., Fischer, J., Rosendahl, J., Marot, A., Elamly, M., Casper, M., Lammert, F., McQuillin, A., Zopf, S., Spengler, U., Marhenke, S., Kirstein, M. M., Vogel, A., Eyer, F., von Felden, J., Wege, H., Buch, T., Schafmayer, C., Braun, F., Deltenre, P., Berg, T., Morgan, M. Y. & Hampe, J., 07.2018, In: AM J GASTROENTEROL. 113, 7, p. 1099Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Transarterial chemoembolization versus sorafenib in patients with hepatocellular carcinoma and extrahepatic disease
Kirstein, M. M., Voigtländer, T., Schweitzer, N., Hinrichs, J. B., Marquardt, J., Wörns, M-A., Kloeckner, R., Fründt, T. W., Ittrich, H., Wacker, F., Rodt, T., Manns, M. P., Wege, H., Weinmann, A. & Vogel, A., 03.2018, In: UNITED EUR GASTROENT. 6, 2, p. 238-246 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Versorgung bei kompensierter Leberzirrhose 2018 – Evidenzbasierte prophylaktische Maßnahmen
Karkmann, K., Piecha, F., Rünzi, A. C., Schulz, L., von Wulffen, M., Benten, D., Kluwe, J. & Wege, H., 01.2018, In: Z GASTROENTEROL. 56, 1, p. 55-69 15 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Neue Optionen in der Systemtherapie des hepatozellulären Karzinoms
Wege, H. & Schulze, K., 2018, In: TUMORDIAGN THER. 9, 39, p. 590-594Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Multi-color RGB marking enables clonality assessment of liver tumors in a murine xenograft model
Thomaschewski, M., Riecken, K., Unrau, L., Volz, T., Cornils, K., Ittrich, H., Heim, D., Wege, H., Akgün, E., Lütgehetmann, M., Dieckhoff, J., Köpke, M., Dandri, M., Benten, D. & Fehse, B., 29.12.2017, In: ONCOTARGET. 8, 70, p. 115582-115595 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating tumor cells as liquid biomarker for high HCC recurrence risk after curative liver resection
von Felden, J., Schulze, K., Krech, T., Ewald, F., Nashan, B., Pantel, K., Lohse, A. W., Riethdorf, S. & Wege, H., 27.10.2017, In: ONCOTARGET. 8, 52, p. 89978-89987 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High expression of micro RNA-135A in hepatocellular carcinoma is associated with recurrence within 12 months after resection
von Felden, J., Heim, D., Schulze, K., Krech, T., Ewald, F., Nashan, B., Lohse, A. W. & Wege, H., 18.01.2017, In: BMC CANCER. 17, 1, p. 60Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Indikationsstellung für operative Eingriffe und perioperatives Management bei Transplantierten und Immunsupprimierten
Wege, H., Benten, D. & Sterneck, M., 01.12.2016, In: Allgemein- und Viszeralchirurgie up2date. 10, 06, p. 453-464Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
First- and Second-Line Targeted Systemic Therapy in Hepatocellular Carcinoma-An Update on Patient Selection and Response Evaluation
von Felden, J., Schulze, K., Gil-Ibanez, I., Werner, T. & Wege, H., 28.11.2016, In: DIAGNOSTICS. 6, 4, p. E44Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inflammation-Induced Expression and Secretion of MicroRNA 122 Leads to Reduced Blood Levels of Kidney-derived Erythropoietin and Anemia
Rivkin, M., Simerzin, A., Zorde-Khvalevsky, E., Chai, C., Yuval, J. B., Rosenberg, N., Harari-Steinfeld, R., Schneider, R., Amir, G., Condiotti, R., Heikenwalder, M., Weber, A., Schramm, C., Wege, H., Kluwe, J., Galun, E. & Giladi, H., 11.2016, In: GASTROENTEROLOGY. 151, 5, p. 999-1010.e3Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Systemic inflammation in decompensated cirrhosis Characterization and role in acute-on-chronic liver failure
Clària, J., Stauber, R. E., Coenraad, M. J., Moreau, R., Jalan, R., Pavesi, M., Amorós, À., Titos, E., Alcaraz-Quiles, J., Oettl, K., Morales-Ruiz, M., Angeli, P., Domenicali, M., Alessandria, C., Gerbes, A., Wendon, J., Nevens, F., Trebicka, J., Laleman, W., Saliba, F., Welzel, T. M., Albillos, A., Gustot, T., Benten, D., Durand, F., Ginès, P., Bernardi, M., Arroyo, V. & CANONIC Study Investigators of the EASL-CLIF Consortium and the European Foundation for the Study of Chronic Liver Failure (EF-CLIF), 10.2016, In: HEPATOLOGY. 64, 4, p. 1249-64Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress response
Heim, D., Gil-Ibanez, I., Herden, J., Parplys, A. C., Borgmann, K., Schmidt-Arras, D., Lohse, A. W., Rose-John, S. & Wege, H., 23.08.2016, In: ONCOTARGET. 7, 34, p. 55639-55648Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Resminostat plus sorafenib as second-line therapy of advanced hepatocellular carcinoma - The SHELTER study
Bitzer, M., Horger, M., Giannini, E. G., Ganten, T. M., Wörns, M. A., Siveke, J. T., Dollinger, M. M., Gerken, G., Scheulen, M. E., Wege, H., Zagonel, V., Cillo, U., Trevisani, F., Santoro, A., Montesarchio, V., Malek, N. P., Holzapfel, J., Herz, T., Ammendola, A. S., Pegoraro, S., Hauns, B., Mais, A., Lauer, U. M., Henning, S. W. & Hentsch, B., 08.2016, In: J HEPATOL. 65, 2, p. 280-8Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling
Wolf, J., Waetzig, G. H., Chalaris, A., Reinheimer, T. M., Wege, H., Rose-John, S. & Garbers, C., 29.07.2016, In: J BIOL CHEM. 291, 31, p. 16186-96Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Aktuelle Therapiekonzepte für lokale Cholangiokarzinome
Seehofer, D., Brunner, TB. & Wege, H., 24.10.2015, In: ONKOLOGE. 10, p. 1054 - 1063Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adjuvant chemotherapy with gemcitabine and cisplatin compared to observation after curative intent resection of cholangiocarcinoma and muscle invasive gallbladder carcinoma (ACTICCA-1 trial) - a randomized, multidisciplinary, multinational phase III trial
Stein, A., Arnold, D., Bridgewater, J., Goldstein, D., Jensen, L. H., Klümpen, H-J., Lohse, A. W., Nashan, B., Primrose, J., Schrum, S., Shannon, J., Vettorazzi, E. & Wege, H., 31.07.2015, In: BMC CANCER. 15, p. Art. 564Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral insertional mutagenesis in telomerase-immortalized hepatocytes identifies RIPK4 as novel tumor suppressor in human hepatocarcinogenesis
Heim, D., Cornils, K., Schulze, K., Fehse, B., Lohse, A. W., Brümmendorf, T. H. & Wege, H., 2015, In: ONCOGENE. 34, 3, p. 385-393Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Specific genomic and transcriptomic aberrations in tumors induced by partial hepatectomy of a chronically inflamed murine liver
Ella, E., Heim, D., Stoyanov, E., Harari-Steinfeld, R., Steinfeld, I., Pappo, O., Perlman, T. S., Nachmansson, N., Rivkin, L., Olam, D., Abramovitch, R., Wege, H., Galun, E. & Goldenberg, D., 15.11.2014, In: ONCOTARGET. 5, 21, p. 10318-10331 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure
Jalan, R., Saliba, F., Pavesi, M., Amoros, A., Moreau, R., Ginès, P., Levesque, E., Durand, F., Angeli, P., Caraceni, P., Hopf, C., Alessandria, C., Rodriguez, E., Solis-Muñoz, P., Laleman, W., Trebicka, J., Zeuzem, S., Gustot, T., Mookerjee, R., Elkrief, L., Soriano, G., Cordoba, J., Morando, F., Gerbes, A., Agarwal, B., Samuel, D., Bernardi, M., Arroyo, V. & CANONIC Study Investigators of the EASL–CLIF Consortium, 01.11.2014, In: J HEPATOL. 61, 5, p. 1038-1047 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TACE plus sorafenib for the treatment of hepatocellular carcinoma: results of the multicenter, phase II SOCRATES trial
Erhardt, A., Kolligs, F., Dollinger, M., Schott, E., Wege, H., Bitzer, M., Gog, C., Lammert, F., Schuchmann, M., Walter, C., Blondin, D., Ohmann, C. & Häussinger, D., 01.11.2014, In: CANCER CHEMOTH PHARM. 74, 5, p. 947-954 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
New foe treated with old guns - supportive role of steroids in the treatment of acute severe hepatitis E
Sebode, M., Pischke, S., Lütgehetmann, M., Polywka, S., Quaas, A., Lohse, A. W. & Wege, H., 01.01.2014, In: BMC GASTROENTEROL. 14, 191Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transduction of fetal mice with a feline lentiviral vector induces liver tumors which exhibit an E2F activation signature
Condiotti, R., Goldenberg, D., Giladi, H., Schnitzer-Perlman, T., Waddington, S. N., Buckley, S. M., Heim, D., Cheung, W., Themis, M., Coutelle, C., Simerzin, A., Osejindu, E., Wege, H., Themis, M. & Galun, E., 01.01.2014, In: MOL THER. 22, 1, p. 59-68 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The diagnosis and treatment of cholangiocarcinoma
Vogel, A., Wege, H., Caca, K., Nashan, B. & Neumann, U., 2014, In: DTSCH ARZTEBL INT. 111, 44, p. 748-54 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Diagnostik und Therapie des hepatozellulären Karzinoms
Greten, T. F., Malek, N. P., Schmidt, S., Arends, J., Bartenstein, P., Bechstein, W., Bernatik, T., Bitzer, M., Chavan, A., Dollinger, M., Domagk, D., Drognitz, O., Düx, M., Farkas, S., Folprecht, G., Galle, P., Geißler, M., Gerken, G., Habermehl, D., Helmberger, T., Herfarth, K., Hoffmann, R. T., Holtmann, M., Huppert, P., Jakobs, T., Keller, M., Klempnauer, J., Kolligs, F., Körber, J., Lang, H., Lehner, F., Lordick, F., Lubienski, A., Manns, M. P., Mahnken, A., Möhler, M., Mönch, C., Neuhaus, P., Niederau, C., Ocker, M., Otto, G., Pereira, P., Pott, G., Riemer, J., Ringe, K., Ritterbusch, U., Rummeny, E., Schirmacher, P., Schlitt, H. J., Schlottmann, K., Schmitz, V., Schuler, A., Schulze-Bergkamen, H., von Schweinitz, D., Seehofer, D., Sitter, H., Straßburg, C. P., Stroszczynski, C., Strobel, D., Tannapfel, A., Trojan, J., van Thiel, I., Vogel, A., Wacker, F., Wedemeyer, H., Wege, H., Weinmann, A., Wittekind, C., Wörmann, B. & Zech, C. J., 01.11.2013, In: Z GASTROENTEROL. 51, 11, p. 1269-326 58 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Presence of EpCAM-positive circulating tumor cells as biomarker for systemic disease strongly correlates to survival in patients with hepatocellular carcinoma
Schulze, K., Gasch, C., Staufer, K., Nashan, B., Lohse, A. W., Pantel, K., Riethdorf, S. & Wege, H., 01.11.2013, In: INT J CANCER. 133, 9, p. 2165-71 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The NTPase/helicase domain of hepatitis C virus nonstructural protein 3 inhibits protein kinase C independently of its NTPase activity
Hartjen, P., Höchst, B., Heim, D., von der Kammer, H., Lucke, J., Reinholz, M., Baier, A., Smeets, R., Wege, H., Borowski, P. & Schulze Zur Wiesch, J., 01.09.2013, In: CELL MOL BIOL LETT. 18, 3, p. 447-58 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis
Moreau, R., Jalan, R., Gines, P., Pavesi, M., Angeli, P., Cordoba, J., Durand, F., Gustot, T., Saliba, F., Domenicali, M., Gerbes, A., Wendon, J., Alessandria, C., Laleman, W., Zeuzem, S., Trebicka, J., Bernardi, M., Arroyo, V. & CANONIC Study Investigators of the EASL–CLIF Consortium, 01.06.2013, In: GASTROENTEROLOGY. 144, 7, p. 1426-37, 1437.e1-9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A needle in a haystack: Identifying biomarkers to personalize systemic therapy in patients with hepatocellular carcinoma
Wege, H., Brümmendorf, T. H. & Gambacorti-Passerini, C., 01.04.2013, In: HEPATOLOGY. 57, 4, p. 1291-3 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
- 2012
Systemtherapie des Leberzellkarzinoms
Wege, H. & Arnold, D., 2012, In: ONKOLOGE. 18, 7, p. 602-610 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Forced activation of β-catenin signaling supports the transformation of hTERT-immortalized human fetal hepatocytes.
Wege, H., Heim, D., Lütgehetmann, M., Dierlamm, J., Lohse, A. W. & Brümmendorf, T. H., 2011, In: MOL CANCER RES. 9, 9, p. 1222-1231 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells.
Brassat, U., Balabanov, S., Bali, D., Dierlamm, J., Balabanov, M., Hartmann, U., Sirma, H., Günes, C., Wege, H., Fehse, B., Gontarewicz, A., Dikomey, E., Borgmann, K. & Brümmendorf, T., 2011, In: EXP HEMATOL. 39, 1, p. 62-66 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT.
Sass, G., Klinger, N., Sirma, H., Hashemolhosseini, S., Hellerbrand, C., Neureiter, D., Wege, H., Ocker, M. & Tiegs, G., 2011, In: INT J ONCOL. 39, 2, p. 433-442 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rapid quantification of telomerase activity employing an improved real-time telomeric repeat amplification protocol in clinical tissue samples eliminates interference by PCR inhibitors
Schriefer, P., Günes, C. & Wege, H., 2011, In: J Cancer Sci Ther. 3, 8, p. 176-180 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SU5416 induces premature senescence in endothelial progenitor cells from patients with age-related macular degeneration.
Berna-Thill, M., Berna, M., Kunst, F., Wege, H., Strunnikova, N. V., Gordiyenko, N., Grierson, R., Richard, G. & Csaky, K. G., 2011, In: MOL VIS. 17, p. 85-98Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Telomere und Telomerase in Zellalterung und Karzinogenese
Wege, H. & Brümmendorf, T., 2010, In: BIOspektrum. 3, p. 271-273Research output: SCORING: Contribution to journal › SCORING: Journal article › Research
- 2009
Aurora kinase inhibitor PHA-739358 suppresses growth of hepatocellular carcinoma in vitro and in a xenograft mouse model.
Benten, D., Keller, G., Quaas, A., Schrader, J., Gontarewicz, A., Balabanov, S., Balabanov, M., Wege, H., Moll, J., Lohse, A. W. & Brümmendorf, T., 2009, In: NEOPLASIA. 11, 9, p. 934-944 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatic stem and progenitor cells in liver diseases and hepatocarcinogenesis.
Heim, D. & Wege, H., 2009, In: Minerva Gastroenterol Dietol. 55, 2, p. 111-121 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Telomerase-Inhibitoren
Wege, H. & Brümmendorf, T., 2009, Molekulare Therapie in der Hämatologie/Onkologie. Bremen: Uni-Med, 9 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research
Telomeres and telomerase in chronic myeloid leukaemia: impact for pathogenesis, disease progression and targeted therapy.
Keller, G., Brassat, U., Balabanov, M., Heim, D., Wege, H. & Brümmendorf, T., 2009, In: HEMATOL ONCOL. 27, 3, p. 123-129 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Absence of oncogenic transformation despite acquisition of cytogenetic aberrations in long-term cultured telomerase-immortalized human fetal hepatocytes.
Haker, B., Fuchs, S., Dierlamm, J., Brümmendorf, T. & Wege, H., 2007, In: CANCER LETT. 256, 1, p. 120-127 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Regeneration in pig livers by compensatory hyperplasia induces high levels of telomerase activity.
Wege, H., Müller, A., Müller, L., Petri, S., Petersen, J. & Hillert, C., 2007, In: Comp Hepatol. 6, p. 6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Telomerase activation in liver regeneration and hepatocarcinogenesis: Dr. Jekyll or Mr. Hyde?
Wege, H. & Brümmendorf, T., 2007, In: CURR STEM CELL RES T. 2, 1, p. 31-38 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2004
Differentiation of human and mouse embryonic stem cells along a hepatocyte lineage
Shirahashi, H., Wu, J., Yamamoto, N., Catana, A., Wege, H., Wager, B., Okita, K. & Zern, M. A., 01.01.2004, In: CELL TRANSPLANT. 13, 3, p. 197-211 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2003
Telomerase reconstitution immortalizes human fetal hepatocytes without disrupting their differentiation potential
Wege, H., Le, H. T., Chui, M. S., Liu, L., Wu, J., Giri, R., Malhi, H., Sappal, B. S., Kumaran, V., Gupta, S. & Zern, M. A., 01.02.2003, In: GASTROENTEROLOGY. 124, 2, p. 432-44 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity
Wege, H., Chui, M. S., Le, H. T., Tran, J. M. & Zern, M. A., 15.01.2003, In: NUCLEIC ACIDS RES. 31, 2, p. E3-3Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In vitro expansion of human hepatocytes is restricted by telomere-dependent replicative aging
Wege, H., Chui, M. S., Le, H. T., Strom, S. C. & Zern, M. A., 01.01.2003, In: CELL TRANSPLANT. 12, 8, p. 897-906 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2001
Cationic lipid polymerization as a novel approach for constructing new DNA delivery agents
Wu, J., Lizarzaburu, M. E., Kurth, M. J., Liu, L., Wege, H., Zern, M. A. & Nantz, M. H., 2001, In: BIOCONJUGATE CHEM. 12, 2, p. 251-7 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review