Research ExplorerScientific StaffHenning Wege Publications

PD Dr. med. ID: 31648

Henning Wege

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Affiliations
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Publications

  1. 2024

  2. Characteristics and outcomes of immunotherapy-related liver injury in patients with hepatocellular carcinoma versus other advanced solid tumours

    Celsa, C., Cabibbo, G., Am Fulgenzi, C., Scheiner, B., Antonio d'Alessio, Manfredi, G. F., Nishida, N., Ang, C., Marron, T. U., Saeed, A., Wietharn, B., Pinter, M., Cheon, J., Huang, Y-H., Lee, P-C., Phen, S., Gampa, A., Pillai, A., Vivaldi, C., Salani, F., Masi, G., Roehlen, N., Thimme, R., Vogel, A., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Galle, P. R., Kudo, M., Rimassa, L., Singal, A. G., El Tomb, P., Ulahannan, S., Parisi, A., Chon, H. J., Hsu, W-F., Stefanini, B., Verzoni, E., Giusti, R., Veccia, A., Catino, A., Aprile, G., Guglielmini, P. F., Di Napoli, M., Ermacora, P., Antonuzzo, L., Rossi, E., Verderame, F., Zustovich, F., Ficorella, C., Di Pietro, F. R., Battelli, N., Negrini, G., Grossi, F., Bordonaro, R., Pipitone, S., Banzi, M., Ricciardi, S., Laera, L., Russo, A., De Giorgi, U., Cavanna, L., Sorarù, M., Montesarchio, V., Bordi, P., Brunetti, L., Pinto, C., Bersanelli, M., Cammà, C., Cortellini, A. & Pinato, D. J., 03.2024, In: J HEPATOL. 80, 3, p. 431-442 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. A meta-analysis and real-world cohort study on the sex-related differences in efficacy and safety of immunotherapy for hepatocellular carcinoma

    Balcar, L., Scheiner, B., Fulgenzi, C. A. M., D'Alessio, A., Pomej, K., Roig, M. B., Meyer, E. L., Che, J., Nishida, N., Lee, P-C., Wu, L., Ang, C., Krall, A., Saeed, A., Stefanini, B., Cammarota, A., Pressiani, T., Abugabal, Y. I., Chamseddine, S., Wietharn, B., Parisi, A., Huang, Y-H., Phen, S., Vivaldi, C., Salani, F., Masi, G., Bettinger, D., Vogel, A., von Felden, J., Schulze, K., Silletta, M., Trauner, M., Samson, A., Wege, H., Piscaglia, F., Galle, P. R., Stauber, R., Kudo, M., Singal, A. G., Itani, A., Ulahannan, S. V., Parikh, N. D., Cortellini, A., Kaseb, A., Rimassa, L., Chon, H. J., Pinato, D. J. & Pinter, M., 02.2024, In: JHEP REP. 6, 2, p. 100982

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. 2023

  5. EpCAM-positive circulating tumor cells and serum AFP levels predict outcome after curative resection of hepatocellular carcinoma

    Kocheise, L., Schoenlein, M., Behrends, B., Joerg, V., Casar, C., Fründt, T. W., Renné, T., Heumann, A., Li, J., Huber, S., Lohse, A. W., Pantel, K., Riethdorf, S., Wege, H., Schulze, K. & von Felden, J., 27.11.2023, In: SCI REP-UK. 13, 1, p. 20827

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Efficacy and safety of atezolizumab/bevacizumab in patients with HCC after prior systemic therapy: A global, observational study

    Joerg, V., Scheiner, B., D Alessio, A., Fulgenzi, C. A. M., Schönlein, M., Kocheise, L., Lohse, A. W., Huber, S., Wege, H., Kaseb, A., Wang, Y., Mathew, A., Kuang, A., Muzaffar, M., Abugabal, Y. I., Chamseddine, S., Phen, S., Cheon, J., Lee, P-C., Balcar, L., Krall, A., Ang, C., Wu, L., Saeed, A., Huang, Y-H., Bengsch, B., Rimassa, L., Weinmann, A., Stauber, R., Korolewicz, J., Pinter, M., Singal, A. G., Chon, H. J., Pinato, D. J., Schulze, K. & von Felden, J., 01.11.2023, In: HEPATOL COMMUN. 7, 11, e0302.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Impact of body mass index in patients receiving atezolizumab plus bevacizumab for hepatocellular carcinoma

    Vithayathil, M., D'Alessio, A., Fulgenzi, C. A. M., Nishida, N., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Saeed, A., Wietharn, B., Hildebrand, H., Wu, L., Ang, C., Marron, T. U., Weinmann, A., Galle, P. R., Bettinger, D., Bengsch, B., Vogel, A., Balcar, L., Scheiner, B., Lee, P-C., Huang, Y-H., Amara, S., Muzaffar, M., Naqash, A. R., Cammarota, A., Zanuso, V., Pressiani, T., Pinter, M., Cortellini, A., Kudo, M., Rimassa, L., Pinato, D. J. & Sharma, R., 08.2023, In: HEPATOL INT. 17, 4, p. 904-914 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. S3-Leitlinie Diagnostik und Therapie biliärer Karzinome: Kurzversion

    Bitzer, M., Groß, S., Albert, J., Boda-Heggemann, J., Brunner, T., Caspari, R., De Toni, E., Dombrowski, F., Evert, M., Geier, A., Gkika, E., Götz, M., Helmberger, T., Hoffmann, R-T., Huppert, P., Kautz, A., Krug, D., Fougère, C. L., Lang, H., Lenz, P., Lüdde, T., Mahnken, A., Nadalin, S., Nguyen, H. H. P., Ockenga, J., Oldhafer, K., Paprottka, P., Pereira, P., Persigehl, T., Plentz, R., Pohl, J., Recken, H., Reimer, P., Riemer, J., Ritterbusch, U., Roeb, E., Rüssel, J., Schellhaas, B., Schirmacher, P., Schlitt, H. J., Schmid, I., Schuler, A., Seehofer, D., Sinn, M., Stengel, A., Stoll, C., Tannapfel, A., Taubert, A., Tholen, R., Trojan, J., van Thiel, I., Vogel, A., Vogl, T., Wacker, F., Waidmann, O., Wedemeyer, H., Wege, H., Wildner, D., Wörns, M-A., Galle, P. & Malek, N., 04.2023, In: Z GASTROENTEROL. 61, 4, p. 420-440 21 p.

    Research output: SCORING: Contribution to journal › Guideline, recommendation, statement › Transfer

  9. S3-Leitlinie Diagnostik und Therapie biliärer Karzinome – Langversion

    Bitzer, M., Groß, S., Albert, J., Boda-Heggemann, J., Brunner, T., Caspari, R., De Toni, E., Dombrowski, F., Evert, M., Geier, A., Gkika, E., Götz, M., Helmberger, T., Hoffmann, R-T., Huppert, P., Kautz, A., Krug, D., Fougère, C. L., Lang, H., Lenz, P., Lüdde, T., Mahnken, A., Nadalin, S., Nguyen, H. H. P., Ockenga, J., Oldhafer, K., Paprottka, P., Pereira, P., Persigehl, T., Plentz, R., Pohl, J., Recken, H., Reimer, P., Riemer, J., Ritterbusch, U., Roeb, E., Rüssel, J., Schellhaas, B., Schirmacher, P., Schlitt, H. J., Schmid, I., Schuler, A., Seehofer, D., Sinn, M., Stengel, A., Stoll, C., Tannapfel, A., Taubert, A., Tholen, R., Trojan, J., van Thiel, I., Vogel, A., Vogl, T., Wacker, F., Waidmann, O., Wedemeyer, H., Wege, H., Wildner, D., Wörns, M-A., Galle, P. & Malek, N., 04.2023, In: Z GASTROENTEROL. 61, 4, p. e92-e156 65 p.

    Research output: SCORING: Contribution to journal › Guideline, recommendation, statement › Transfer

  10. 2022

  11. Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios as Prognostic Biomarkers in Unresectable Hepatocellular Carcinoma Treated with Atezolizumab plus Bevacizumab

    Wu, Y. L., Fulgenzi, C. A. M., D'Alessio, A., Cheon, J., Nishida, N., Saeed, A., Wietharn, B., Cammarota, A., Pressiani, T., Personeni, N., Pinter, M., Scheiner, B., Balcar, L., Huang, Y-H., Phen, S., Naqash, A. R., Vivaldi, C., Salani, F., Masi, G., Bettinger, D., Vogel, A., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Galle, P. R., Kudo, M., Rimassa, L., Singal, A. G., Sharma, R., Cortellini, A., Gaillard, V. E., Chon, H. J., Pinato, D. J. & Ang, C., 26.11.2022, In: CANCERS. 14, 23, 5834.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Impact of older age in patients receiving atezolizumab and bevacizumab for hepatocellular carcinoma

    Vithayathil, M., D'Alessio, A., Fulgenzi, C. A. M., Nishida, N., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Saeed, A., Wietharn, B., Hildebrand, H., Wu, L., Ang, C., Marron, T. U., Weinmann, A., Galle, P. R., Bettinger, D., Bengsch, B., Vogel, A., Balcar, L., Scheiner, B., Lee, P-C., Huang, Y-H., Amara, S., Muzaffar, M., Naqash, A. R., Cammarota, A., Personeni, N., Pressiani, T., Pinter, M., Cortellini, A., Kudo, M., Rimassa, L., Pinato, D. J. & Sharma, R., 11.2022, In: LIVER INT. 42, 11, p. 2538-2547 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study

    Fulgenzi, C. A. M., Cheon, J., D'Alessio, A., Nishida, N., Ang, C., Marron, T. U., Wu, L., Saeed, A., Wietharn, B., Cammarota, A., Pressiani, T., Personeni, N., Pinter, M., Scheiner, B., Balcar, L., Napolitano, A., Huang, Y-H., Phen, S., Naqash, A. R., Vivaldi, C., Salani, F., Masi, G., Bettinger, D., Vogel, A., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Galle, P. R., Kudo, M., Rimassa, L., Singal, A. G., Sharma, R., Cortellini, A., Gaillard, V. E., Chon, H. J. & Pinato, D. J., 11.2022, In: EUR J CANCER. 175, p. 204-213 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Preliminary evidence of safety and tolerability of atezolizumab plus bevacizumab in patients with hepatocellular carcinoma and Child-Pugh A and B cirrhosis: a real-world study

    D'Alessio, A., Fulgenzi, C. A. M., Nishida, N., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Gaillard, V. E., Saeed, A., Wietharn, B., Hildebrand, H., Wu, L., Ang, C., Marron, T. U., Weinmann, A., Galle, P. R., Bettinger, D., Bengsch, B., Vogel, A., Balcar, L., Scheiner, B., Lee, P-C., Huang, Y-H., Amara, S., Muzaffar, M., Naqash, A. R., Cammarota, A., Personeni, N., Pressiani, T., Sharma, R., Pinter, M., Cortellini, A., Kudo, M., Rimassa, L. & Pinato, D. J., 10.2022, In: HEPATOLOGY. 76, 4, p. 1000-1012 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Real-World Data for Lenvatinib in Hepatocellular Carcinoma (ELEVATOR): A Retrospective Multicenter Study

    Welland, S., Leyh, C., Finkelmeier, F., Jefremow, A., Shmanko, K., Gonzalez-Carmona, M. A., Kandulski, A., Jeliazkova, P., Best, J., Fründt, T. W., Djanani, A., Pangerl, M., Maieron, A., Greil, R., Fricke, C., Sookthai, D., Günther, R., Schmiderer, A., Wege, H., Venerito, M., Ehmer, U., Müller, M., Strassburg, C. P., Weinmann, A., Siebler, J., Waidmann, O., Lange, C. M., Saborowski, A. & Vogel, A., 06.2022, In: LIVER CANCER. 11, 3, p. 219-232 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Atezolizumab and bevacizumab with transarterial chemoembolization in hepatocellular carcinoma: the DEMAND trial protocol

    Khaled, N. B., Seidensticker, M., Ricke, J., Mayerle, J., Oehrle, B., Rössler, D., Teupser, D., Ehmer, U., Bitzer, M., Waldschmidt, D., Fuchs, M., Reuken, P. A., Lange, C. M., Wege, H., Kandulski, A., Dechêne, A., Venerito, M., Berres, M-L., Luedde, T., Kubisch, I., Reiter, F. P. & De Toni, E. N., 04.2022, In: FUTURE ONCOL. 18, 12, p. 1423-1435 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  17. Equal Efficacy and Safety Profile in Elderly Patients with Hepatocellular Carcinoma Receiving Palliative Treatment

    Fründt, T. W., Casar, C., von Felden, J., Schöler, U., Priebe, M., Kraczyk, J., Ahrend, H., Salamon, J., Adam, G., Huber, S., Lohse, A. W., Wege, H. & Schulze, K., 01.02.2022, In: CANCERS. 14, 3, 768.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Der Einsatz der immunonkologischen Therapie beim hepatozellulären Karzinom im Kontext der Lebertransplantation Eine interdisziplinäre Risiko-Nutzen-Abwägung

    Vogel, A., Sterneck, M., Vondran, F., Waidmann, O., Klein, I., Lindig, U., Nadalin, S., Settmacher, U., Tacke, F., Schlitt, H. J. & Wege, H., 02.2022, In: Z GASTROENTEROL. 60, 2, p. 184-191 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  19. Gallengangskrebs: Zu häufig eine zu späte Diagnose

    Wege, H., 02.2022, In: MMW Fortschr Med. 164, Suppl 4, p. 19-21 3 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Prognosis of patients with hepatocellular carcinoma treated with immunotherapy - development and validation of the CRAFITY score

    Scheiner, B., Pomej, K., Kirstein, M. M., Hucke, F., Finkelmeier, F., Waidmann, O., Himmelsbach, V., Schulze, K., von Felden, J., Fründt, T. W., Stadler, M., Heinzl, H., Shmanko, K., Spahn, S., Radu, P., Siebenhüner, A. R., Mertens, J. C., Rahbari, N. N., Kütting, F., Waldschmidt, D-T., Ebert, M. P., Teufel, A., De Dosso, S., Pinato, D. J., Pressiani, T., Meischl, T., Balcar, L., Müller, C., Mandorfer, M., Reiberger, T., Trauner, M., Personeni, N., Rimassa, L., Bitzer, M., Trojan, J., Weinmann, A., Wege, H., Dufour, J-F., Peck-Radosavljevic, M., Vogel, A. & Pinter, M., 02.2022, In: J HEPATOL. 76, 2, p. 353-363 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. S3-Leitlinie: Diagnostik und Therapie biliärer Karzinome: Langversion 2.0 – Juni 2021 – AWMF-Registernummer: 032-053OL

    Bitzer, M., Voesch, S., Albert, J., Bartenstein, P., Bechstein, W., Blödt, S., Brunner, T., Dombrowski, F., Evert, M., Follmann, M., La Fougère, C., Freudenberger, P., Geier, A., Gkika, E., Götz, M., Hammes, E., Helmberger, T., Hoffmann, R. T., Hofmann, W. P., Huppert, P., Kautz, A., Knötgen, G., Körber, J., Krug, D., Lammert, F., Lang, H., Langer, T., Lenz, P., Mahnken, A., Meining, A., Micke, O., Nadalin, S., Nguyen, H. P., Ockenga, J., Oldhafer, K., Paprottka, P., Paradies, K., Pereira, P., Persigehl, T., Plauth, M., Plentz, R., Pohl, J., Riemer, J., Reimer, P., Ringwald, J., Ritterbusch, U., Roeb, E., Schellhaas, B., Schirmacher, P., Schmid, I., Schuler, A., von Schweinitz, D., Seehofer, D., Sinn, M., Stein, A., Stengel, A., Steubesand, N., Stoll, C., Tannapfel, A., Taubert, A., Trojan, J., van Thiel, I., Tholen, R., Vogel, A., Vogl, T., Vorwerk, H., Wacker, F., Waidmann, O., Wedemeyer, H., Wege, H., Wildner, D., Wittekind, C., Wörns, M. A., Galle, P. & Malek, N., 02.2022, In: Z GASTROENTEROL. 60, 2, p. 219-238

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  22. S3-Leitlinie: Diagnostik und Therapie des hepatozellulären Karzinoms

    Sabrina, V., Michael, B., Jörg, A., Peter, B., Wolf, B., Susanne, B., Thomas, B., Frank, D., Matthias, E., Markus, F., Christian, L. F., Paul, F., Andreas, G., Eleni, G., Martin, G., Elke, H., Thomas, H., Ralf-Thorsten, H., Wolf-Peter, H., Peter, H., Achim, K., Gabi, K., Jürgen, K., David, K., Frank, L., Hauke, L., Thomas, L., Philipp, L., Andreas, M., Alexander, M., Oliver, M., Silvio, N., Huu Phuc, N., Johann, O., Karl-Jürgen, O., Philipp, P., Kerstin, P., Philippe, P., Thorsten, P., Mathias, P., Ruben, P., Jürgen, P., Jutta, R., Peter, R., Johanna, R., Ulrike, R., Elke, R., Barbara, S., Peter, S., Irene, S., Andreas, S., Dietrich, V. S., Daniel, S., Marianne, S., Alexander, S., Andreas, S., Nadine, S., Christian, S., Andrea, T., Anne, T., Jörg, T., Ingo, V. T., Reina, T., Arndt, V., Thomas, V., Hilke, V., Frank, W., Oliver, W., Heiner, W., Henning, W., Dane, W., Christian, W., Marcus-Alexander, W., Peter, G. & Nisar, M., 01.2022, In: Z GASTROENTEROL. 60, 1, p. e56-e130

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  23. S3-Leitlinie: Diagnostik und Therapie des hepatozellulären Karzinoms – Kurzversion 2.00 – Juni 2021, AWMF-Registernummer: 032-053OL

    Sabrina, V., Michael, B., Jörg, A., Peter, B., Wolf, B., Susanne, B., Thomas, B., Frank, D., Matthias, E., Markus, F., Christian, L. F., Paul, F., Andreas, G., Eleni, G., Martin, G., Elke, H., Thomas, H., Ralf-Thorsten, H., Wolf-Peter, H., Peter, H., Achim, K., Gabi, K., Jürgen, K., David, K., Frank, L., Hauke, L., Thomas, L., Philipp, L., Andreas, M., Alexander, M., Oliver, M., Silvio, N., Huu Phuc, N., Johann, O., Karl-Jürgen, O., Philipp, P., Kerstin, P., Philippe, P., Thorsten, P., Mathias, P., Ruben, P., Jürgen, P., Jutta, R., Peter, R., Johanna, R., Ulrike, R., Elke, R., Barbara, S., Peter, S., Irene, S., Andreas, S., Dietrich, V. S., Daniel, S., Marianne, S., Alexander, S., Andreas, S., Nadine, S., Christian, S., Andrea, T., Anne, T., Jörg, T., Ingo, V. T., Reina, T., Arndt, V., Thomas, V., Hilke, V., Frank, W., Oliver, W., Heiner, W., Henning, W., Dane, W., Christian, W., Marcus-Alexander, W., Peter, G. & Nisar, M., 01.2022, In: Z GASTROENTEROL. 60, 1, p. 81-107 27 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  24. Circulating tumor cells as a preoperative risk marker for occult metastases in patients with resectable cholangiocarcinoma

    Fründt, T., von Felden, J., Krause, J., Heumann, A., Li, J., Riethdorf, S., Pantel, K., Huber, S., Lohse, A. W., Wege, H. & Schulze, K., 2022, In: FRONT ONCOL. 12, 941660.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. 2021

  26. Rare variants of primary liver cancer: Fibrolamellar, combined, and sarcomatoid hepatocellular carcinomas

    Wege, H., Schulze, K., von Felden, J., Calderaro, J., Reig, M. & European Reference Network on Hepatological Diseases (ERN RARE-LIVER), 01.11.2021, In: EUR J MED GENET. 64, 11, 104313.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  27. Early Detection of Hepatocellular Carcinoma Since the Introduction of the German Clinical Practice Guideline in 2013

    Schulze, K., Felden, J. V., Fründt, T. W., Krause, J., Werner, T., Casar, C., Jung, C., Ittrich, H., Sterneck, M., Li, J., Heumann, A., Fischer, L., Adam, G., Lohse, A. W. & Wege, H., 09.08.2021, In: DTSCH ARZTEBL INT. 118, 31-32, p. 540-541 2 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  28. Cabozantinib in Advanced Hepatocellular Carcinoma: Efficacy and Safety Data from an International Multicenter Real-Life Cohort

    Finkelmeier, F., Scheiner, B., Leyh, C., Best, J., Fründt, T. W., Czauderna, C., Beutel, A., Bettinger, D., Weiß, J., Meischl, T., Kütting, F., Waldschmidt, D-T., Radu, P., Schultheiß, M., Peiffer, K-H., Ettrich, T. J., Weinmann, A., Wege, H., Venerito, M., Dufour, J-F., Lange, C. M., Pinter, M. & Waidmann, O., 07.2021, In: LIVER CANCER. 10, 4, p. 360-369 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Assessing the impact of COVID-19 on liver cancer management (CERO-19)

    Muñoz-Martínez, S., Sapena, V., Forner, A., Nault, J-C., Sapisochin, G., Rimassa, L., Sangro, B., Bruix, J., Sanduzzi-Zamparelli, M., Hołówko, W., El Kassas, M., Mocan, T., Bouattour, M., Merle, P., Hoogwater, F. J. H., Alqahtani, S. A., Reeves, H. L., Pinato, D. J., Giorgakis, E., Meyer, T., Villadsen, G. E., Wege, H., Salati, M., Mínguez, B., Di Costanzo, G. G., Roderburg, C., Tacke, F., Varela, M., Galle, P. R., Alvares-da-Silva, M. R., Trojan, J., Bridgewater, J., Cabibbo, G., Toso, C., Lachenmayer, A., Casadei-Gardini, A., Toyoda, H., Lüdde, T., Villani, R., Matilla Peña, A. M., Guedes Leal, C. R., Ronzoni, M., Delgado, M., Perelló, C., Pascual, S., Lledó, J. L., Argemi, J., Basu, B., da Fonseca, L., Acevedo, J., Siebenhüner, A. R., Braconi, C., Meyers, B. M., Granito, A., Sala, M., Rodríguez Lope, C., Blaise, L., Romero-Gómez, M., Piñero, F., Gomez, D., Mello, V., Pinheiro Alves, R. C., França, A., Branco, F., Brandi, G., Pereira, G., Coll, S., Guarino, M., Benítez, C., Anders, M. M., Bandi, J. C., Vergara, M., Calvo, M., Peck-Radosavljevic, M., García-Juárez, I., Cardinale, V., Lozano, M., Gambato, M., Okolicsanyi, S., Arraez, D. M., Elvevi, A., Muñoz, A. E., Lué, A., Iavarone, M. & Reig, M., 06.2021, In: JHEP REP. 3, 3, 100260.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Diagnostic and Prognostic Value of miR-16, miR-146a, miR-192 and miR-221 in Exosomes of Hepatocellular Carcinoma and Liver Cirrhosis Patients

    Fründt, T., Krause, L., Hussey, E., Steinbach, B., Köhler, D., von Felden, J., Schulze, K., Lohse, A. W., Wege, H. & Schwarzenbach, H., 19.05.2021, In: CANCERS. 13, 10, p. 2484

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. NASH limits anti-tumour surveillance in immunotherapy-treated HCC

    Pfister, D., Núñez, N. G., Pinyol, R., Govaere, O., Pinter, M., Szydlowska, M., Gupta, R., Qiu, M., Deczkowska, A., Weiner, A., Müller, F., Sinha, A., Friebel, E., Engleitner, T., Lenggenhager, D., Moncsek, A., Heide, D., Stirm, K., Kosla, J., Kotsiliti, E., Leone, V., Dudek, M., Yousuf, S., Inverso, D., Singh, I., Teijeiro, A., Castet, F., Montironi, C., Haber, P. K., Tiniakos, D., Bedossa, P., Cockell, S., Younes, R., Vacca, M., Marra, F., Schattenberg, J. M., Allison, M., Bugianesi, E., Ratziu, V., Pressiani, T., D'Alessio, A., Personeni, N., Rimassa, L., Daly, A. K., Scheiner, B., Pomej, K., Kirstein, M. M., Vogel, A., Peck-Radosavljevic, M., Hucke, F., Finkelmeier, F., Waidmann, O., Trojan, J., Schulze, K., Wege, H., Koch, S., Weinmann, A., Bueter, M., Rössler, F., Siebenhüner, A., De Dosso, S., Mallm, J-P., Umansky, V., Jugold, M., Luedde, T., Schietinger, A., Schirmacher, P., Emu, B., Augustin, H. G., Billeter, A., Müller-Stich, B., Kikuchi, H., Duda, D. G., Kütting, F., Waldschmidt, D-T., Ebert, M. P., Rahbari, N., Mei, H. E., Schulz, A. R., Ringelhan, M., Malek, N., Spahn, S., Bitzer, M., Ruiz de Galarreta, M., Lujambio, A., Dufour, J-F., Marron, T. U., Kaseb, A., Kudo, M., Huang, Y-H., Djouder, N., Wolter, K., Zender, L., Marche, P. N., Decaens, T., Pinato, D. J., Rad, R., Mertens, J. C., Weber, A., Unger, K., Meissner, F., Roth, S., Jilkova, Z. M., Claassen, M., Anstee, Q. M., Amit, I., Knolle, P., Becher, B., Llovet, J. M. & Heikenwalder, M., 04.2021, In: NATURE. 592, 7854, p. 450-456 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Sequential Systemic Treatment in Advanced Hepatocellular Carcinoma Is Able to Prolong Median Survival to More than 3 Years in a Selected Real-World Cohort

    von Felden, J., Karkmann, K., Ittrich, H., Gil-Ibanez, I., Fründt, T., Krause, J., Lohse, A. W., Wege, H. & Schulze, K., 03.2021, In: VISC MED. 37, 2, p. 87-93 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Low incidence of COVID-19 in a prospective cohort of patients with liver cirrhosis and hepatocellular carcinoma treated at a tertiary medical center during the 2020 pandemic

    Fründt, T., Kuballa, L., Lütgehetman, M., Nörz, D., Arend, H., Brehm, T. T., Schulze Zur Wiesch, J., Horvatits, T., Horvatits, K., Huber, S., Wege, H. & Kluwe, J., 2021, In: PLOS ONE. 16, 12, p. e0258450

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. 2020

  35. Hepatocellular carcinoma: Intratumoral EpCAM-positive cancer stem cell heterogeneity identifies high-risk tumor subtype

    Krause, J., von Felden, J., Casar, C., Fründt, T. W., Galaski, J., Schmidt, C., Jung, C., Ittrich, H., Weidemann, S. A., Krech, T., Heumann, A., Li, J., Fischer, L., Sauter, G., Lohse, A. W., Wege, H. & Schulze, K., 23.11.2020, In: BMC CANCER. 20, 1, p. 1130

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. Perforation of the ascending colon during implantation of an indwelling peritoneal catheter: a case report

    Paparoupa, M., Wege, H., Creutzfeldt, A., Sebode, M., Uzunoglu, F. G., Boenisch, O., Nierhaus, A., Izbicki, J. R. & Kluge, S., 16.10.2020, In: BMC GASTROENTEROL. 20, 1, p. 345

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. SOP Transarterielle Chemoembolisation zur Tumortherapie

    Ittrich, H., Wege, H. & Schrader, J., 07.09.2020, In: Gastroenterologie up2date. 2020, 16, p. 201-208 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  38. Elevated Aspartate Aminotransferase to Alanine Aminotransferase Ratio Predicts Poor Outcome in Hepatocellular Carcinoma

    von Felden, J., Wege, H. & Schulze, K., 09.2020, In: HEPATOL COMMUN. 4, 9, p. 1382-1383 2 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  39. Genetic variation in HSD17B13 reduces the risk of developing cirrhosis and hepatocellular carcinoma in alcohol misusers

    Stickel, F., Lutz, P., Buch, S., Nischalke, H. D., Silva, I., Rausch, V., Fischer, J., Weiss, K. H., Gotthardt, D., Rosendahl, J., Marot, A., Elamly, M., Krawczyk, M., Casper, M., Lammert, F., Buckley, T. W., McQuillin, A., Spengler, U., Eyer, F., Vogel, A., Marhenke, S., von Felden, J., Wege, H., Sharma, R., Atkinson, S., Franke, A., Nehring, S., Moser, V., Schafmayer, C., Spahr, L., Lackner, C., Stauber, R. E., Canbay, A., Link, A., Valenti, L., Grove, J. I., Aithal, G. P., Marquardt, J. U., Fateen, W., Zopf, S., Dufour, J-F., Trebicka, J., Datz, C., Deltenre, P., Mueller, S., Berg, T., Hampe, J. & Morgan, M. Y., 07.2020, In: HEPATOLOGY. 72, 1, p. 88-102 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Gallengangs- und Gallenblasenkarzinome: auf dem Weg zur personalisierten Therapie

    Sinn, M., Wege, H. & Stein, A., 04.2020, In: DEUT MED WOCHENSCHR. 145, 7, p. 442-446 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. GALAD Score Detects Early Hepatocellular Carcinoma in an International Cohort of Patients With Nonalcoholic Steatohepatitis

    Best, J., Bechmann, L. P., Sowa, J-P., Sydor, S., Dechêne, A., Pflanz, K., Bedreli, S., Schotten, C., Geier, A., Berg, T., Fischer, J., Vogel, A., Bantel, H., Weinmann, A., Schattenberg, J. M., Huber, Y., Wege, H., von Felden, J., Schulze, K., Bettinger, D., Thimme, R., Sinner, F., Schütte, K., Weiss, K. H., Toyoda, H., Yasuda, S., Kumada, T., Berhane, S., Wichert, M., Heider, D., Gerken, G., Johnson, P. & Canbay, A., 03.2020, In: CLIN GASTROENTEROL H. 18, 3, p. 728-735.e4

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. 2019

  43. SOP Spontan bakterielle Peritonitis bei Leberzirrhose

    Wege, H. & Kluwe, J., 12.2019, In: Gastroenterologie up2date. 2019, 15, p. 321-325 5 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  44. Treatment Lines in Hepatocellular Carcinoma

    Wege, H., Li, J. & Ittrich, H., 08.2019, In: VISC MED. 35, 4, p. 266-272 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  45. Doxorubicin-loaded nanoparticles for patients with advanced hepatocellular carcinoma after sorafenib treatment failure (RELIVE): A phase 3 randomised controlled trial

    Merle, P., Blanc, J-F., Phelip, J-M., Pelletier, G., Bronowicki, J-P., Touchefeu, Y., Pageaux, G., Gerolami, R., Habersetzer, F., Nguyen-Khac, E., Casadei-Gardini, A., Borbath, I., Tran, A., Wege, H., Saad, A. S., Colombo, M., Abergel, A., Richou, C., Waked, I., Yee, N. S., Molé, A., Attali, P., Le Boulicaut, J., Vasseur, B. & RELIVE Investigators, 06.2019, In: LANCET GASTROENTEROL. 4, 6, p. 454-465 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. Programmed cell death protein-1 (PD-1)-targeted immunotherapy in advanced hepatocellular carcinoma: efficacy and safety data from an international multicentre real-world cohort

    Scheiner, B., Kirstein, M. M., Hucke, F., Finkelmeier, F., Schulze, K., von Felden, J., Koch, S., Schwabl, P., Hinrichs, J. B., Waneck, F., Waidmann, O., Reiberger, T., Müller, C., Sieghart, W., Trauner, M., Weinmann, A., Wege, H., Trojan, J., Peck-Radosavljevic, M., Vogel, A. & Pinter, M., 05.2019, In: ALIMENT PHARM THER. 49, 10, p. 1323-1333 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Vaccinia-based oncolytic immunotherapy Pexastimogene Devacirepvec in patients with advanced hepatocellular carcinoma after sorafenib failure: a randomized multicenter Phase IIb trial (TRAVERSE)

    Moehler, M., Heo, J., Lee, H. C., Tak, W. Y., Chao, Y., Paik, S. W., Yim, H. J., Byun, K. S., Baron, A., Ungerechts, G., Jonker, D., Ruo, L., Cho, M., Kaubisch, A., Wege, H., Merle, P., Ebert, O., Habersetzer, F., Blanc, J. F., Rosmorduc, O., Lencioni, R., Patt, R., Leen, A. M., Foerster, F., Homerin, M., Stojkowitz, N., Lusky, M., Limacher, J. M., Hennequi, M., Gaspar, N., McFadden, B., De Silva, N., Shen, D., Pelusio, A., Kirn, D. H., Breitbach, C. J. & Burke, J. M., 2019, In: ONCOIMMUNOLOGY. 8, 8, p. 1615817

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. 2018

  49. Fast and facile analysis of glycosylation and phosphorylation of fibrinogen from human plasma-correlation with liver cancer and liver cirrhosis

    Nagel, T., Klaus, F., Ibanez, I. G., Wege, H., Lohse, A. & Meyer, B., 12.2018, In: ANAL BIOANAL CHEM. 410, 30, p. 7965-7977 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. Genetic variants in PNPLA3 and TM6SF2 predispose to the development of hepatocellular carcinoma in individuals with alcohol-related cirrhosis

    Stickel, F., Buch, S., Nischalke, H. D., Weiss, K. H., Gotthardt, D., Fischer, J., Rosendahl, J., Marot, A., Elamly, M., Casper, M., Lammert, F., McQuillin, A., Zopf, S., Spengler, U., Marhenke, S., Kirstein, M. M., Vogel, A., Eyer, F., von Felden, J., Wege, H., Buch, T., Schafmayer, C., Braun, F., Deltenre, P., Berg, T., Morgan, M. Y. & Hampe, J., 10.2018, In: AM J GASTROENTEROL. 113, 10, p. 1475-1483 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. Correction: Genetic Variants in PNPLA3 and TM6SF2 Predispose to the Development of Hepatocellular Carcinoma in Individuals With Alcohol-Related Cirrhosis

    Stickel, F., Buch, S., Nischalke, H. D., Weiss, K. H., Gotthardt, D., Fischer, J., Rosendahl, J., Marot, A., Elamly, M., Casper, M., Lammert, F., McQuillin, A., Zopf, S., Spengler, U., Marhenke, S., Kirstein, M. M., Vogel, A., Eyer, F., von Felden, J., Wege, H., Buch, T., Schafmayer, C., Braun, F., Deltenre, P., Berg, T., Morgan, M. Y. & Hampe, J., 07.2018, In: AM J GASTROENTEROL. 113, 7, p. 1099

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  52. Transarterial chemoembolization versus sorafenib in patients with hepatocellular carcinoma and extrahepatic disease

    Kirstein, M. M., Voigtländer, T., Schweitzer, N., Hinrichs, J. B., Marquardt, J., Wörns, M-A., Kloeckner, R., Fründt, T. W., Ittrich, H., Wacker, F., Rodt, T., Manns, M. P., Wege, H., Weinmann, A. & Vogel, A., 03.2018, In: UNITED EUR GASTROENT. 6, 2, p. 238-246 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. Versorgung bei kompensierter Leberzirrhose 2018 – Evidenzbasierte prophylaktische Maßnahmen

    Karkmann, K., Piecha, F., Rünzi, A. C., Schulz, L., von Wulffen, M., Benten, D., Kluwe, J. & Wege, H., 01.2018, In: Z GASTROENTEROL. 56, 1, p. 55-69 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  54. Neue Optionen in der Systemtherapie des hepatozellulären Karzinoms

    Wege, H. & Schulze, K., 2018, In: TUMORDIAGN THER. 9, 39, p. 590-594

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  55. 2017

  56. Multi-color RGB marking enables clonality assessment of liver tumors in a murine xenograft model

    Thomaschewski, M., Riecken, K., Unrau, L., Volz, T., Cornils, K., Ittrich, H., Heim, D., Wege, H., Akgün, E., Lütgehetmann, M., Dieckhoff, J., Köpke, M., Dandri, M., Benten, D. & Fehse, B., 29.12.2017, In: ONCOTARGET. 8, 70, p. 115582-115595 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  57. Circulating tumor cells as liquid biomarker for high HCC recurrence risk after curative liver resection

    von Felden, J., Schulze, K., Krech, T., Ewald, F., Nashan, B., Pantel, K., Lohse, A. W., Riethdorf, S. & Wege, H., 27.10.2017, In: ONCOTARGET. 8, 52, p. 89978-89987 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  58. High expression of micro RNA-135A in hepatocellular carcinoma is associated with recurrence within 12 months after resection

    von Felden, J., Heim, D., Schulze, K., Krech, T., Ewald, F., Nashan, B., Lohse, A. W. & Wege, H., 18.01.2017, In: BMC CANCER. 17, 1, p. 60

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  59. 2016

  60. Indikationsstellung für operative Eingriffe und perioperatives Management bei Transplantierten und Immunsupprimierten

    Wege, H., Benten, D. & Sterneck, M., 01.12.2016, In: Allgemein- und Viszeralchirurgie up2date. 10, 06, p. 453-464

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  61. First- and Second-Line Targeted Systemic Therapy in Hepatocellular Carcinoma-An Update on Patient Selection and Response Evaluation

    von Felden, J., Schulze, K., Gil-Ibanez, I., Werner, T. & Wege, H., 28.11.2016, In: DIAGNOSTICS. 6, 4, p. E44

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  62. Inflammation-Induced Expression and Secretion of MicroRNA 122 Leads to Reduced Blood Levels of Kidney-derived Erythropoietin and Anemia

    Rivkin, M., Simerzin, A., Zorde-Khvalevsky, E., Chai, C., Yuval, J. B., Rosenberg, N., Harari-Steinfeld, R., Schneider, R., Amir, G., Condiotti, R., Heikenwalder, M., Weber, A., Schramm, C., Wege, H., Kluwe, J., Galun, E. & Giladi, H., 11.2016, In: GASTROENTEROLOGY. 151, 5, p. 999-1010.e3

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  63. Systemic inflammation in decompensated cirrhosis Characterization and role in acute-on-chronic liver failure

    Clària, J., Stauber, R. E., Coenraad, M. J., Moreau, R., Jalan, R., Pavesi, M., Amorós, À., Titos, E., Alcaraz-Quiles, J., Oettl, K., Morales-Ruiz, M., Angeli, P., Domenicali, M., Alessandria, C., Gerbes, A., Wendon, J., Nevens, F., Trebicka, J., Laleman, W., Saliba, F., Welzel, T. M., Albillos, A., Gustot, T., Benten, D., Durand, F., Ginès, P., Bernardi, M., Arroyo, V. & CANONIC Study Investigators of the EASL-CLIF Consortium and the European Foundation for the Study of Chronic Liver Failure (EF-CLIF), 10.2016, In: HEPATOLOGY. 64, 4, p. 1249-64

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  64. Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress response

    Heim, D., Gil-Ibanez, I., Herden, J., Parplys, A. C., Borgmann, K., Schmidt-Arras, D., Lohse, A. W., Rose-John, S. & Wege, H., 23.08.2016, In: ONCOTARGET. 7, 34, p. 55639-55648

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  65. Resminostat plus sorafenib as second-line therapy of advanced hepatocellular carcinoma - The SHELTER study

    Bitzer, M., Horger, M., Giannini, E. G., Ganten, T. M., Wörns, M. A., Siveke, J. T., Dollinger, M. M., Gerken, G., Scheulen, M. E., Wege, H., Zagonel, V., Cillo, U., Trevisani, F., Santoro, A., Montesarchio, V., Malek, N. P., Holzapfel, J., Herz, T., Ammendola, A. S., Pegoraro, S., Hauns, B., Mais, A., Lauer, U. M., Henning, S. W. & Hentsch, B., 08.2016, In: J HEPATOL. 65, 2, p. 280-8

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  66. Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling

    Wolf, J., Waetzig, G. H., Chalaris, A., Reinheimer, T. M., Wege, H., Rose-John, S. & Garbers, C., 29.07.2016, In: J BIOL CHEM. 291, 31, p. 16186-96

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  67. 2015

  68. Aktuelle Therapiekonzepte für lokale Cholangiokarzinome

    Seehofer, D., Brunner, TB. & Wege, H., 24.10.2015, In: ONKOLOGE. 10, p. 1054 - 1063

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  69. Adjuvant chemotherapy with gemcitabine and cisplatin compared to observation after curative intent resection of cholangiocarcinoma and muscle invasive gallbladder carcinoma (ACTICCA-1 trial) - a randomized, multidisciplinary, multinational phase III trial

    Stein, A., Arnold, D., Bridgewater, J., Goldstein, D., Jensen, L. H., Klümpen, H-J., Lohse, A. W., Nashan, B., Primrose, J., Schrum, S., Shannon, J., Vettorazzi, E. & Wege, H., 31.07.2015, In: BMC CANCER. 15, p. Art. 564

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  70. Retroviral insertional mutagenesis in telomerase-immortalized hepatocytes identifies RIPK4 as novel tumor suppressor in human hepatocarcinogenesis

    Heim, D., Cornils, K., Schulze, K., Fehse, B., Lohse, A. W., Brümmendorf, T. H. & Wege, H., 2015, In: ONCOGENE. 34, 3, p. 385-393

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  71. 2014

  72. Specific genomic and transcriptomic aberrations in tumors induced by partial hepatectomy of a chronically inflamed murine liver

    Ella, E., Heim, D., Stoyanov, E., Harari-Steinfeld, R., Steinfeld, I., Pappo, O., Perlman, T. S., Nachmansson, N., Rivkin, L., Olam, D., Abramovitch, R., Wege, H., Galun, E. & Goldenberg, D., 15.11.2014, In: ONCOTARGET. 5, 21, p. 10318-10331 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  73. Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure

    Jalan, R., Saliba, F., Pavesi, M., Amoros, A., Moreau, R., Ginès, P., Levesque, E., Durand, F., Angeli, P., Caraceni, P., Hopf, C., Alessandria, C., Rodriguez, E., Solis-Muñoz, P., Laleman, W., Trebicka, J., Zeuzem, S., Gustot, T., Mookerjee, R., Elkrief, L., Soriano, G., Cordoba, J., Morando, F., Gerbes, A., Agarwal, B., Samuel, D., Bernardi, M., Arroyo, V. & CANONIC Study Investigators of the EASL–CLIF Consortium, 01.11.2014, In: J HEPATOL. 61, 5, p. 1038-1047 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  74. TACE plus sorafenib for the treatment of hepatocellular carcinoma: results of the multicenter, phase II SOCRATES trial

    Erhardt, A., Kolligs, F., Dollinger, M., Schott, E., Wege, H., Bitzer, M., Gog, C., Lammert, F., Schuchmann, M., Walter, C., Blondin, D., Ohmann, C. & Häussinger, D., 01.11.2014, In: CANCER CHEMOTH PHARM. 74, 5, p. 947-954 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  75. New foe treated with old guns - supportive role of steroids in the treatment of acute severe hepatitis E

    Sebode, M., Pischke, S., Lütgehetmann, M., Polywka, S., Quaas, A., Lohse, A. W. & Wege, H., 01.01.2014, In: BMC GASTROENTEROL. 14, 191

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  76. Transduction of fetal mice with a feline lentiviral vector induces liver tumors which exhibit an E2F activation signature

    Condiotti, R., Goldenberg, D., Giladi, H., Schnitzer-Perlman, T., Waddington, S. N., Buckley, S. M., Heim, D., Cheung, W., Themis, M., Coutelle, C., Simerzin, A., Osejindu, E., Wege, H., Themis, M. & Galun, E., 01.01.2014, In: MOL THER. 22, 1, p. 59-68 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  77. The diagnosis and treatment of cholangiocarcinoma

    Vogel, A., Wege, H., Caca, K., Nashan, B. & Neumann, U., 2014, In: DTSCH ARZTEBL INT. 111, 44, p. 748-54 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  78. 2013

  79. Diagnostik und Therapie des hepatozellulären Karzinoms

    Greten, T. F., Malek, N. P., Schmidt, S., Arends, J., Bartenstein, P., Bechstein, W., Bernatik, T., Bitzer, M., Chavan, A., Dollinger, M., Domagk, D., Drognitz, O., Düx, M., Farkas, S., Folprecht, G., Galle, P., Geißler, M., Gerken, G., Habermehl, D., Helmberger, T., Herfarth, K., Hoffmann, R. T., Holtmann, M., Huppert, P., Jakobs, T., Keller, M., Klempnauer, J., Kolligs, F., Körber, J., Lang, H., Lehner, F., Lordick, F., Lubienski, A., Manns, M. P., Mahnken, A., Möhler, M., Mönch, C., Neuhaus, P., Niederau, C., Ocker, M., Otto, G., Pereira, P., Pott, G., Riemer, J., Ringe, K., Ritterbusch, U., Rummeny, E., Schirmacher, P., Schlitt, H. J., Schlottmann, K., Schmitz, V., Schuler, A., Schulze-Bergkamen, H., von Schweinitz, D., Seehofer, D., Sitter, H., Straßburg, C. P., Stroszczynski, C., Strobel, D., Tannapfel, A., Trojan, J., van Thiel, I., Vogel, A., Wacker, F., Wedemeyer, H., Wege, H., Weinmann, A., Wittekind, C., Wörmann, B. & Zech, C. J., 01.11.2013, In: Z GASTROENTEROL. 51, 11, p. 1269-326 58 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  80. Presence of EpCAM-positive circulating tumor cells as biomarker for systemic disease strongly correlates to survival in patients with hepatocellular carcinoma

    Schulze, K., Gasch, C., Staufer, K., Nashan, B., Lohse, A. W., Pantel, K., Riethdorf, S. & Wege, H., 01.11.2013, In: INT J CANCER. 133, 9, p. 2165-71 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  81. The NTPase/helicase domain of hepatitis C virus nonstructural protein 3 inhibits protein kinase C independently of its NTPase activity

    Hartjen, P., Höchst, B., Heim, D., von der Kammer, H., Lucke, J., Reinholz, M., Baier, A., Smeets, R., Wege, H., Borowski, P. & Schulze Zur Wiesch, J., 01.09.2013, In: CELL MOL BIOL LETT. 18, 3, p. 447-58 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  82. Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis

    Moreau, R., Jalan, R., Gines, P., Pavesi, M., Angeli, P., Cordoba, J., Durand, F., Gustot, T., Saliba, F., Domenicali, M., Gerbes, A., Wendon, J., Alessandria, C., Laleman, W., Zeuzem, S., Trebicka, J., Bernardi, M., Arroyo, V. & CANONIC Study Investigators of the EASL–CLIF Consortium, 01.06.2013, In: GASTROENTEROLOGY. 144, 7, p. 1426-37, 1437.e1-9

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  83. A needle in a haystack: Identifying biomarkers to personalize systemic therapy in patients with hepatocellular carcinoma

    Wege, H., Brümmendorf, T. H. & Gambacorti-Passerini, C., 01.04.2013, In: HEPATOLOGY. 57, 4, p. 1291-3 3 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  84. 2012

  85. Systemtherapie des Leberzellkarzinoms

    Wege, H. & Arnold, D., 2012, In: ONKOLOGE. 18, 7, p. 602-610 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  86. 2011

  87. Forced activation of β-catenin signaling supports the transformation of hTERT-immortalized human fetal hepatocytes.

    Wege, H., Heim, D., Lütgehetmann, M., Dierlamm, J., Lohse, A. W. & Brümmendorf, T. H., 2011, In: MOL CANCER RES. 9, 9, p. 1222-1231 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  88. Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells.

    Brassat, U., Balabanov, S., Bali, D., Dierlamm, J., Balabanov, M., Hartmann, U., Sirma, H., Günes, C., Wege, H., Fehse, B., Gontarewicz, A., Dikomey, E., Borgmann, K. & Brümmendorf, T., 2011, In: EXP HEMATOL. 39, 1, p. 62-66 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  89. Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT.

    Sass, G., Klinger, N., Sirma, H., Hashemolhosseini, S., Hellerbrand, C., Neureiter, D., Wege, H., Ocker, M. & Tiegs, G., 2011, In: INT J ONCOL. 39, 2, p. 433-442 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  90. Rapid quantification of telomerase activity employing an improved real-time telomeric repeat amplification protocol in clinical tissue samples eliminates interference by PCR inhibitors

    Schriefer, P., Günes, C. & Wege, H., 2011, In: J Cancer Sci Ther. 3, 8, p. 176-180 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  91. SU5416 induces premature senescence in endothelial progenitor cells from patients with age-related macular degeneration.

    Berna-Thill, M., Berna, M., Kunst, F., Wege, H., Strunnikova, N. V., Gordiyenko, N., Grierson, R., Richard, G. & Csaky, K. G., 2011, In: MOL VIS. 17, p. 85-98

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  92. 2010

  93. Telomere und Telomerase in Zellalterung und Karzinogenese

    Wege, H. & Brümmendorf, T., 2010, In: BIOspektrum. 3, p. 271-273

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research

  94. 2009

  95. Aurora kinase inhibitor PHA-739358 suppresses growth of hepatocellular carcinoma in vitro and in a xenograft mouse model.

    Benten, D., Keller, G., Quaas, A., Schrader, J., Gontarewicz, A., Balabanov, S., Balabanov, M., Wege, H., Moll, J., Lohse, A. W. & Brümmendorf, T., 2009, In: NEOPLASIA. 11, 9, p. 934-944 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  96. Hepatic stem and progenitor cells in liver diseases and hepatocarcinogenesis.

    Heim, D. & Wege, H., 2009, In: Minerva Gastroenterol Dietol. 55, 2, p. 111-121 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  97. Telomerase-Inhibitoren

    Wege, H. & Brümmendorf, T., 2009, Molekulare Therapie in der Hämatologie/Onkologie. Bremen: Uni-Med, 9 p.

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research

  98. Telomeres and telomerase in chronic myeloid leukaemia: impact for pathogenesis, disease progression and targeted therapy.

    Keller, G., Brassat, U., Balabanov, M., Heim, D., Wege, H. & Brümmendorf, T., 2009, In: HEMATOL ONCOL. 27, 3, p. 123-129 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  99. 2007

  100. Absence of oncogenic transformation despite acquisition of cytogenetic aberrations in long-term cultured telomerase-immortalized human fetal hepatocytes.

    Haker, B., Fuchs, S., Dierlamm, J., Brümmendorf, T. & Wege, H., 2007, In: CANCER LETT. 256, 1, p. 120-127 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  101. Regeneration in pig livers by compensatory hyperplasia induces high levels of telomerase activity.

    Wege, H., Müller, A., Müller, L., Petri, S., Petersen, J. & Hillert, C., 2007, In: Comp Hepatol. 6, p. 6

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  102. Telomerase activation in liver regeneration and hepatocarcinogenesis: Dr. Jekyll or Mr. Hyde?

    Wege, H. & Brümmendorf, T., 2007, In: CURR STEM CELL RES T. 2, 1, p. 31-38 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  103. 2004

  104. Differentiation of human and mouse embryonic stem cells along a hepatocyte lineage

    Shirahashi, H., Wu, J., Yamamoto, N., Catana, A., Wege, H., Wager, B., Okita, K. & Zern, M. A., 01.01.2004, In: CELL TRANSPLANT. 13, 3, p. 197-211 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  105. 2003

  106. Telomerase reconstitution immortalizes human fetal hepatocytes without disrupting their differentiation potential

    Wege, H., Le, H. T., Chui, M. S., Liu, L., Wu, J., Giri, R., Malhi, H., Sappal, B. S., Kumaran, V., Gupta, S. & Zern, M. A., 01.02.2003, In: GASTROENTEROLOGY. 124, 2, p. 432-44 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  107. SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity

    Wege, H., Chui, M. S., Le, H. T., Tran, J. M. & Zern, M. A., 15.01.2003, In: NUCLEIC ACIDS RES. 31, 2, p. E3-3

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  108. In vitro expansion of human hepatocytes is restricted by telomere-dependent replicative aging

    Wege, H., Chui, M. S., Le, H. T., Strom, S. C. & Zern, M. A., 01.01.2003, In: CELL TRANSPLANT. 12, 8, p. 897-906 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  109. 2001

  110. Cationic lipid polymerization as a novel approach for constructing new DNA delivery agents

    Wu, J., Lizarzaburu, M. E., Kurth, M. J., Liu, L., Wege, H., Zern, M. A. & Nantz, M. H., 2001, In: BIOCONJUGATE CHEM. 12, 2, p. 251-7 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review