Prof.Dr.rer.nat ID: 15692247
Immo Prinz
Publications
- 2010
Constant TCR triggering suggests that the TCR expressed on intestinal intraepithelial γδ T cells is functional in vivo
Malinarich, F. H., Grabski, E., Worbs, T., Chennupati, V., Haas, J. D., Schmitz, S., Candia, E., Quera, R., Malissen, B., Förster, R., Hermoso, M. & Prinz, I., 12.2010, In: EUR J IMMUNOL. 40, 12, p. 3378-88 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Expression of miRNAs miR-133b and miR-206 in the Il17a/f locus is co-regulated with IL-17 production in αβ and γδ T cells
Haas, J. D., Nistala, K., Petermann, F., Saran, N., Chennupati, V., Schmitz, S., Korn, T., Wedderburn, L. R., Förster, R., Krueger, A. & Prinz, I., 2011, In: PLOS ONE. 6, 5, p. e20171Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic labeling reveals altered turnover and stability of innate lymphocytes in latent mouse cytomegalovirus infection
Busche, A., Schmitz, S., Fleige, H., Robbins, S. H., Walzer, T., Stewart, C. A., Förster, R., Messerle, M. & Prinz, I., 01.03.2011, In: J IMMUNOL. 186, 5, p. 2918-25 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dynamics of the interaction of γδ T cells with their neighbors in vivo
Prinz, I., 07.2011, In: CELL MOL LIFE SCI. 68, 14, p. 2391-8 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Commensal gut flora reduces susceptibility to experimentally induced colitis via T-cell-derived interleukin-10
Pils, M. C., Bleich, A., Prinz, I., Fasnacht, N., Bollati-Fogolin, M., Schippers, A., Rozell, B. & Müller, W., 10.2011, In: INFLAMM BOWEL DIS. 17, 10, p. 2038-46 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High TCR diversity ensures optimal function and homeostasis of Foxp3+ regulatory T cells
Föhse, L., Suffner, J., Suhre, K., Wahl, B., Lindner, C., Lee, C-W., Schmitz, S., Haas, J. D., Lamprecht, S., Koenecke, C., Bleich, A., Hämmerling, G. J., Malissen, B., Suerbaum, S., Förster, R. & Prinz, I., 11.2011, In: EUR J IMMUNOL. 41, 11, p. 3101-13 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
IFN-γ production by allogeneic Foxp3+ regulatory T cells is essential for preventing experimental graft-versus-host disease.
Koenecke, C., Lee, C-W., Thamm, K., Föhse, L., Schafferus, M., Mittrücker, H. W., Floess, S., Huehn, J., Ganser, A., Förster, R. & Prinz, I., 2012, In: J IMMUNOL. 189, 6, p. 2890-2896 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.
Turner, J. E., Krebs, C., Tittel, A. P., Paust, H-J., Meyer-Schwesinger, C., Bennstein, S. B., Steinmetz, O., Prinz, I., Magnus, T., Korn, T., Stahl, R. A. K., Kurts, C. & Panzer, U., 2012, In: J AM SOC NEPHROL. 23, 9, p. 1486-1495 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Gelderblom, M., Weymar, A., Bernreuther, C., Velden, J., Arunachalam, P., Steinbach, K., Orthey, E., Arumugam, T. V., Leypoldt, F., Simova, O., Thom, V., Friese, M. A., Prinz, I., Hölscher, C., Glatzel, M., Korn, T., Gerloff, C., Tolosa, E. & Magnus, T., 2012, In: BLOOD. 120, 18, p. 3793-3802 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Shift of graft-versus-host-disease target organ tropism by dietary vitamin A
Koenecke, C., Prinz, I., Bubke, A., Schreder, A., Lee, C-W., Pabst, O. & Förster, R., 2012, In: PLOS ONE. 7, 5, p. e38252Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deficient CCR7 signaling promotes TH2 polarization and B-cell activation in vivo
Moschovakis, G. L., Bubke, A., Dittrich-Breiholz, O., Braun, A., Prinz, I., Kremmer, E. & Förster, R., 01.2012, In: EUR J IMMUNOL. 42, 1, p. 48-57 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Induction of BALT in the absence of IL-17
Fleige, H., Haas, J. D., Stahl, F. R., Willenzon, S., Prinz, I. & Förster, R., 01.2012, In: NAT IMMUNOL. 13, 1, p. 1; author reply 2Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine
Lindner, C., Wahl, B., Föhse, L., Suerbaum, S., Macpherson, A. J., Prinz, I. & Pabst, O., 13.02.2012, In: J EXP MED. 209, 2, p. 365-77 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδ T cells are not alone
Prinz, I. & Föhse, L., 04.2012, In: IMMUNOL CELL BIOL. 90, 4, p. 370-1 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dynamic migration of γδ intraepithelial lymphocytes requires occludin
Edelblum, K. L., Shen, L., Weber, C. R., Marchiando, A. M., Clay, B. S., Wang, Y., Prinz, I., Malissen, B., Sperling, A. I. & Turner, J. R., 01.05.2012, In: P NATL ACAD SCI USA. 109, 18, p. 7097-102 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Therapeutic potential of induced and natural FoxP3(+) regulatory T cells for the treatment of Graft-versus-host disease
Prinz, I. & Koenecke, C., 06.2012, In: ARCH IMMUNOL THER EX. 60, 3, p. 183-90 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave
Haas, J. D., Ravens, S., Düber, S., Sandrock, I., Oberdörfer, L., Kashani, E., Chennupati, V., Föhse, L., Naumann, R., Weiss, S., Krueger, A., Förster, R. & Prinz, I., 27.07.2012, In: IMMUNITY. 37, 1, p. 48-59 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
The natural and the inducible interleukin (IL)-17-producing γδ T cells
Chien, Y., Zeng, X. & Prinz, I., 04.2013, In: TRENDS IMMUNOL. 34, 4, p. 151-4 4 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells
Ziętara, N., Łyszkiewicz, M., Witzlau, K., Naumann, R., Hurwitz, R., Langemeier, J., Bohne, J., Sandrock, I., Ballmaier, M., Weiss, S., Prinz, I. & Krueger, A., 30.04.2013, In: P NATL ACAD SCI USA. 110, 18, p. 7407-12 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Donor Vδ1+ γδ T cells expand after allogeneic hematopoietic stem cell transplantation and show reactivity against CMV-infected cells but not against progressing B-CLL
Prinz, I., Thamm, K., Port, M., Weissinger, E. M., Stadler, M., Gabaev, I., Jacobs, R., Ganser, A. & Koenecke, C., 11.05.2013, In: EXP HEMATOL ONCOL. 2, 1, p. 14Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional development of γδ T cells
Prinz, I., Silva-Santos, B. & Pennington, D. J., 08.2013, In: EUR J IMMUNOL. 43, 8, p. 1988-94 7 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Differential postselection proliferation dynamics of αβ T cells, Foxp3+ regulatory T cells, and invariant NKT cells monitored by genetic pulse labeling
Föhse, L., Reinhardt, A., Oberdörfer, L., Schmitz, S., Förster, R., Malissen, B. & Prinz, I., 01.09.2013, In: J IMMUNOL. 191, 5, p. 2384-92 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis
Hammerich, L., Bangen, J. M., Govaere, O., Zimmermann, H. W., Gassler, N., Huss, S., Liedtke, C., Prinz, I., Lira, S. A., Luedde, T., Roskams, T., Trautwein, C., Heymann, F. & Tacke, F., 02.2014, In: HEPATOLOGY. 59, 2, p. 630-42 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Induced and thymus-derived Foxp3⁺ regulatory T cells share a common niche
Huang, Y-J., Haist, V., Baumgärtner, W., Föhse, L., Prinz, I., Suerbaum, S., Floess, S. & Huehn, J., 02.2014, In: EUR J IMMUNOL. 44, 2, p. 460-8 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow
Daussy, C., Faure, F., Mayol, K., Viel, S., Gasteiger, G., Charrier, E., Bienvenu, J., Henry, T., Debien, E., Hasan, U. A., Marvel, J., Yoh, K., Takahashi, S., Prinz, I., de Bernard, S., Buffat, L. & Walzer, T., 10.03.2014, In: J EXP MED. 211, 3, p. 563-77 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs
Fleige, H., Ravens, S., Moschovakis, G. L., Bölter, J., Willenzon, S., Sutter, G., Häussler, S., Kalinke, U., Prinz, I. & Förster, R., 07.04.2014, In: J EXP MED. 211, 4, p. 643-51 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CCR7-mediated migration in the thymus controls γδ T-cell development
Reinhardt, A., Ravens, S., Fleige, H., Haas, J. D., Oberdörfer, L., Łyszkiewicz, M., Förster, R. & Prinz, I., 05.2014, In: EUR J IMMUNOL. 44, 5, p. 1320-9 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Visualization and quantification of monoallelic TCRα gene rearrangement in αβ T cells
Winter, M., Kashani, E., Chennupati, V., Föhse, L. & Prinz, I., 06.2014, In: IMMUNOL CELL BIOL. 92, 5, p. 409-16 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδ T cell subsets play opposing roles in regulating experimental autoimmune encephalomyelitis
Blink, S. E., Caldis, M. W., Goings, G. E., Harp, C. T., Malissen, B., Prinz, I., Xu, D. & Miller, S. D., 07.2014, In: CELL IMMUNOL. 290, 1, p. 39-51 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ontogeny of Innate T Lymphocytes - Some Innate Lymphocytes are More Innate than Others
Vermijlen, D. & Prinz, I., 10.10.2014, In: FRONT IMMUNOL. 5, p. 486Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2015
Limited niche availability suppresses murine intrathymic dendritic-cell development from noncommitted progenitors
Łyszkiewicz, M., Ziętara, N., Föhse, L., Puchałka, J., Diestelhorst, J., Witzlau, K., Prinz, I., Schambach, A. & Krueger, A., 15.01.2015, In: BLOOD. 125, 3, p. 457-64 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A clonotypic Vγ4Jγ1/Vδ5Dδ2Jδ1 innate γδ T-cell population restricted to the CCR6⁺CD27⁻ subset
Kashani, E., Föhse, L., Raha, S., Sandrock, I., Oberdörfer, L., Koenecke, C., Suerbaum, S., Weiss, S. & Prinz, I., 13.03.2015, In: NAT COMMUN. 6, p. 6477Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Testosterone Suppresses Hepatic Inflammation by the Downregulation of IL-17, CXCL-9, and CXCL-10 in a Mouse Model of Experimental Acute Cholangitis
Schwinge, D., Carambia, A., Quaas, A., Krech, T., Wegscheid, C., Tiegs, G., Prinz, I., Lohse, A. W., Herkel, J. & Schramm, C., 15.03.2015, In: J IMMUNOL. 194, 6, p. 2522-30 9 p.Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
Multicongenic fate mapping quantification of dynamics of thymus colonization
Ziętara, N., Łyszkiewicz, M., Puchałka, J., Witzlau, K., Reinhardt, A., Förster, R., Pabst, O., Prinz, I. & Krueger, A., 21.09.2015, In: J EXP MED. 212, 10, p. 1589-601 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδ T cells come to stay: Innate skin memory in the Aldara model
Prinz, I. & Sandrock, I., 11.2015, In: EUR J IMMUNOL. 45, 11, p. 2994-7 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development
Sandrock, I., Ziętara, N., Łyszkiewicz, M., Oberdörfer, L., Witzlau, K., Krueger, A. & Prinz, I., 16.12.2015, In: PLOS ONE. 10, 12, p. e0145010Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Interleukin 17, Produced by γδ T Cells, Contributes to Hepatic Inflammation in a Mouse Model of Biliary Atresia and Is Increased in Livers of Patients
Klemann, C., Schröder, A., Dreier, A., Möhn, N., Dippel, S., Winterberg, T., Wilde, A., Yu, Y., Thorenz, A., Gueler, F., Jörns, A., Tolosa, E., Leonhardt, J., Haas, J. D., Prinz, I., Vieten, G., Petersen, C. & Kuebler, J. F., 01.2016, In: GASTROENTEROLOGY. 150, 1, p. 229-241.e5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation
Yang, B-H., Hagemann, S., Mamareli, P., Lauer, U., Hoffmann, U., Beckstette, M., Föhse, L., Prinz, I., Pezoldt, J., Suerbaum, S., Sparwasser, T., Hamann, A., Floess, S., Huehn, J. & Lochner, M., 03.2016, In: MUCOSAL IMMUNOL. 9, 2, p. 444-57 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17 is not essential for inflammation and chronic pelvic pain development in an experimental model of chronic prostatitis/chronic pelvic pain syndrome
Motrich, R. D., Breser, M. L., Sánchez, L. R., Godoy, G. J., Prinz, I. & Rivero, V. E., 03.2016, In: PAIN. 157, 3, p. 585-597 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Brief Report: Arthritis in KRN T Cell Receptor-Transgenic Mice Does Not Require Interleukin-17 or Th17 Cells
Auger, J. L., Cowan, H. M., Engelson, B. J., Kashem, S. W., Prinz, I. & Binstadt, B. A., 08.2016, In: ARTHRITIS RHEUMATOL. 68, 8, p. 1849-55 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disruption of de novo fatty acid synthesis via acetyl-CoA carboxylase 1 inhibition prevents acute graft-versus-host disease
Raha, S., Raud, B., Oberdörfer, L., Castro, C. N., Schreder, A., Freitag, J., Longerich, T., Lochner, M., Sparwasser, T., Berod, L., Koenecke, C. & Prinz, I., 09.2016, In: EUR J IMMUNOL. 46, 9, p. 2233-8 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interleukin-23-Dependent γ/δ T Cells Produce Interleukin-17 and Accumulate in the Enthesis, Aortic Valve, and Ciliary Body in Mice
Reinhardt, A., Yevsa, T., Worbs, T., Lienenklaus, S., Sandrock, I., Oberdörfer, L., Korn, T., Weiss, S., Förster, R. & Prinz, I., 10.2016, In: ARTHRITIS RHEUMATOL. 68, 10, p. 2476-86 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection
Ravens, S., Schultze-Florey, C., Raha, S., Sandrock, I., Drenker, M., Oberdörfer, L., Reinhardt, A., Ravens, I., Beck, M., Geffers, R., von Kaisenberg, C., Heuser, M., Thol, F., Ganser, A., Förster, R., Koenecke, C. & Prinz, I., 04.2017, In: NAT IMMUNOL. 18, 4, p. 393-401 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Eomes expression reports the progressive differentiation of IFN-γ-producing Th1-like γδ T cells
Lino, C. N. R., Barros-Martins, J., Oberdörfer, L., Walzer, T. & Prinz, I., 06.2017, In: EUR J IMMUNOL. 47, 6, p. 970-981 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reply to Comment : Could γ/δ T Cells Explain Adverse Effects of Zoledronic Acid? Comment on the Article by Reinhardt et al. 2016
Reinhardt, A. & Prinz, I., 06.2017, In: ARTHRITIS RHEUMATOL. 69, 6, p. 1339-1341 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability
Edelblum, K. L., Sharon, G., Singh, G., Odenwald, M. A., Sailer, A., Cao, S., Ravens, S., Thomsen, I., El Bissati, K., McLeod, R., Dong, C., Gurbuxani, S., Prinz, I., Mazmanian, S. K. & Turner, J. R., 10.06.2017, In: CELL MOL GASTROENTER. 4, 2, p. 285-297 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke
Arunachalam, P., Ludewig, P., Melich, P., Arumugam, T. V., Gerloff, C., Prinz, I., Magnus, T. & Gelderblom, M., 07.2017, In: STROKE. 48, 7, p. 1957-1965 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections
Hassane, M., Demon, D., Soulard, D., Fontaine, J., Keller, L. E., Patin, E. C., Porte, R., Prinz, I., Ryffel, B., Kadioglu, A., Veening, J-W., Sirard, J-C., Faveeuw, C., Lamkanfi, M., Trottein, F. & Paget, C., 07.2017, In: MUCOSAL IMMUNOL. 10, 4, p. 1056-1068 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7
Vachharajani, N., Joeris, T., Luu, M., Hartmann, S., Pautz, S., Jenike, E., Pantazis, G., Prinz, I., Hofer, M. J., Steinhoff, U. & Visekruna, A., 01.08.2017, In: ONCOTARGET. 8, 31, p. 50447-50459 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection
Pezoldt, J., Pisano, F., Heine, W., Pasztoi, M., Rosenheinrich, M., Nuss, A. M., Pils, M. C., Prinz, I., Förster, R., Huehn, J. & Dersch, P., 15.09.2017, In: J INFECT DIS. 216, 6, p. 752-760 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review