Sybille Köhler
Publications
- 2024
The proteasome modulates endocytosis specifically in glomerular cells to promote kidney filtration
Sachs, W., Blume, L., Loreth, D., Schebsdat, L., Hatje, F., Koehler, S., Wedekind, U., Sachs, M., Zieliniski, S., Brand, J., Conze, C., Florea, B. I., Heppner, F., Krüger, E., Rinschen, M. M., Kretz, O., Thünauer, R. & Meyer-Schwesinger, C., 01.03.2024, In: NAT COMMUN. 15, 1, p. 1897Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Insights into human kidney function from the study of Drosophila
Koehler, S. & Huber, T. B., 12.2023, In: PEDIATR NEPHROL. 38, 12, p. 3875-3887 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Call for Papers: Podocyte Physiology and Pathophysiology
Köhler, S., Miner, J. H. & Staruschenko, A., 01.05.2023, In: AM J PHYSIOL-RENAL. 324, 5, p. F505-F510Research output: SCORING: Contribution to journal › Editorial › Research
Modeling of ACTN4-Based Podocytopathy Using Drosophila Nephrocytes
Odenthal, J., Dittrich, S., Ludwig, V., Merz, T., Reitmeier, K., Reusch, B., Höhne, M., Cosgun, Z. C., Hohenadel, M., Putnik, J., Göbel, H., Rinschen, M. M., Altmüller, J., Koehler, S., Schermer, B., Benzing, T., Beck, B. B., Brinkkötter, P. T., Habbig, S. & Bartram, M. P., 02.2023, In: KIDNEY INT REP. 8, 2, p. 317-329 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Integrating basic science with translational research: the 13th International Podocyte Conference 2021
Lausecker, F., Koehler, S., Fresquet, M., Naylor, R. W., Tian, P., Wanner, N., Braun, F., Butt, L., Huber, T. B. & Lennon, R., 10.2022, In: KIDNEY INT. 102, 4, p. 708-719 12 p.Research output: SCORING: Contribution to journal › Conference article in journal › Research › peer-review
A protective role for Drosophila Filamin in nephrocytes via Yorkie mediated hypertrophy
Köhler, S., Huber, T. & Denholm, B., 03.08.2022, In: LIFE SCI ALLIANCE. 5, 12, e202101281.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier
Köhler, S., Odenthal, J., Ludwig, V., Unnersjö-Jess, D., Höhne, M., Jüngst, C., Grawe, F., Helmstädter, M., Janku, J. L., Bergmann, C., Hoyer, P. F., Hagmann, H., Walz, G., Bloch, W., Niessen, C. M., Schermer, B., Wodarz, A., Denholm, B., Benzing, T., Iden, S. & Brinkkoetter, P. T., 04.2022, In: KIDNEY INT. 101, 4, p. P733-751Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
The Atypical Cyclin-Dependent Kinase 5 (Cdk5) Guards Podocytes from Apoptosis in Glomerular Disease While Being Dispensable for Podocyte Development
Mangold, N., Pippin, J., Unnersjö-Jess, D., Koehler, S., Shankland, S. J., Brähler, S., Schermer, B., Benzing, T., Brinkkoetter, P. T. & Hagmann, H., 18.09.2021, In: CELLS-BASEL. 10, 9, 2464.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A stressed barrier left behind: stochastic podocyte ablation triggers secondary injury
Koehler, S. & Rinschen, M. M., 01.05.2021, In: AM J PHYSIOL-RENAL. 320, 5, p. F866-F869Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
- 2020
Injured Podocytes Are Sensitized to Angiotensin II-Induced Calcium Signaling
Binz-Lotter, J., Jüngst, C., Rinschen, M. M., Koehler, S., Zentis, P., Schauss, A., Schermer, B., Benzing, T. & Hackl, M. J., 03.2020, In: J AM SOC NEPHROL. 31, 3, p. 532-542 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Proteome Analysis of Isolated Podocytes Reveals Stress Responses in Glomerular Sclerosis
Koehler, S., Kuczkowski, A., Kuehne, L., Jüngst, C., Hoehne, M., Grahammer, F., Eddy, S., Kretzler, M., Beck, B. B., Höhfeld, J., Schermer, B., Benzing, T., Brinkkoetter, P. T. & Rinschen, M. M., 03.2020, In: J AM SOC NEPHROL. 31, 3, p. 544-559 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics
Brinkkoetter, P. T., Bork, T., Salou, S., Liang, W., Mizi, A., Özel, C., Koehler, S., Hagmann, H. H., Ising, C., Kuczkowski, A., Schnyder, S., Abed, A., Schermer, B., Benzing, T., Kretz, O., Puelles, V. G., Lagies, S., Schlimpert, M., Kammerer, B., Handschin, C., Schell, C. & Huber, T. B., 30.04.2019, In: CELL REP. 27, 5, p. 1551-1566.e5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Protein half-life determines expression of proteostatic networks in podocyte differentiation
Schroeter, C. B., Koehler, S., Kann, M., Schermer, B., Benzing, T., Brinkkoetter, P. T. & Rinschen, M. M., 09.2018, In: FASEB J. 32, 9, p. 4696-4713 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes
Koehler, S., Brähler, S., Braun, F., Hagmann, H., Rinschen, M. M., Späth, M. R., Höhne, M., Wunderlich, F. T., Schermer, B., Benzing, T. & Brinkkoetter, P. T., 06.2017, In: KIDNEY INT. 91, 6, p. 1510-1517 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Single and Transient Ca2+ Peaks in Podocytes do not induce Changes in Glomerular Filtration and Perfusion
Koehler, S., Brähler, S., Kuczkowski, A., Binz, J., Hackl, M. J., Hagmann, H., Höhne, M., Vogt, M. C., Wunderlich, C. M., Wunderlich, F. T., Schweda, F., Schermer, B., Benzing, T. & Brinkkoetter, P. T., 19.10.2016, In: SCI REP-UK. 6, p. 35400Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative deep mapping of the cultured podocyte proteome uncovers shifts in proteostatic mechanisms during differentiation
Rinschen, M. M., Schroeter, C. B., Koehler, S., Ising, C., Schermer, B., Kann, M., Benzing, T. & Brinkkoetter, P. T., 01.09.2016, In: AM J PHYSIOL-CELL PH. 311, 3, p. C404-17Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Par3A is dispensable for the function of the glomerular filtration barrier of the kidney
Koehler, S., Tellkamp, F., Niessen, C. M., Bloch, W., Kerjaschki, D., Schermer, B., Benzing, T. & Brinkkoetter, P. T., 01.07.2016, In: AM J PHYSIOL-RENAL. 311, 1, p. F112-9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prohibitin-2 Depletion Unravels Extra-Mitochondrial Functions at the Kidney Filtration Barrier
Ising, C., Bharill, P., Brinkkoetter, S., Brähler, S., Schroeter, C., Koehler, S., Hagmann, H., Merkwirth, C., Höhne, M., Müller, R. U., Fabretti, F., Schermer, B., Bloch, W., Kerjaschki, D., Kurschat, C. E., Benzing, T. & Brinkkoetter, P. T., 05.2016, In: AM J PATHOL. 186, 5, p. 1128-39 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure
Ising, C., Koehler, S., Brähler, S., Merkwirth, C., Höhne, M., Baris, O. R., Hagmann, H., Kann, M., Fabretti, F., Dafinger, C., Bloch, W., Schermer, B., Linkermann, A., Brüning, J. C., Kurschat, C. E., Müller, R-U., Wiesner, R. J., Langer, T., Benzing, T. & Brinkkoetter, P. T., 03.2015, In: EMBO MOL MED. 7, 3, p. 275-87 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review