Dr. ID: 50186
Stadt zur Stadt
Publications
- 2023
ABL-class Genomic Breakpoint Q-PCR: A Patient-specific Approach for MRD Monitoring in Acute Lymphoblastic Leukemia
van Outersterp, I., van der Velden, V. H. J., Hoogeveen, P. G., Vaitkevičienė, G. E., Sonneveld, E., van Haaften, G., Kuiper, R. P., Zur Stadt, U., Escherich, G., Boer, J. M. & den Boer, M. L., 10.2023, In: HEMASPHERE. 7, 10, p. e967Research output: SCORING: Contribution to journal › Letter › Research › peer-review
- 2022
Amsacrine combined with etoposide and methylprednisolone is a feasible and safe component in first-line intensified treatment of pediatric patients with high-risk acute lymphoblastic leukemia in CoALL08-09 trial
Mezger, K., Ebert, S., Muhle, H. E., Stadt, U. Z., Borkhardt, A., Dilloo, D., Faber, J., Feuchtinger, T., Imschweiler, T., Jorch, N., Pekrun, A., Schmid, I., Schramm, F., Zimmermann, M., Horstmann, M. A. & Escherich, G., 12.2022, In: PEDIATR BLOOD CANCER. 69, 12, e29997.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of IG-MYC-breakpoints and their application for quantitative minimal disease monitoring in high-risk pediatric Burkitt-lymphoma and -leukemia
Möker, P., Zur Stadt, U., Zimmermann, M., Alawi, M., Mueller, S., Finger, J., Knörr, F., Riquelme, A., Oschlies, I., Klapper, W., Bradtke, J., Burkhardt, B., Woessmann, W. & Damm-Welk, C., 09.2022, In: LEUKEMIA. 36, 9, p. 2343-2346 4 p.Research output: SCORING: Contribution to journal › Letter › Research
Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acute Lymphoblastic Leukemia Study Group
Escherich, G., Zur Stadt, U., Borkhardt, A., Dilloo, D., Faber, J., Feuchtinger, T., Imschweiler, T., Jorch, N., Pekrun, A., Schmid, I., Schramm, F., Spohn, M., Zimmermann, M. & Horstmann, M. A., 01.05.2022, In: HAEMATOLOGICA. 107, 5, p. 1026-1033 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Minimal residual disease, long-term outcome, and IKZF1 deletions in children and adolescents with Down syndrome and acute lymphocytic leukaemia: a matched cohort study
Michels, N., Boer, J. M., Enshaei, A., Sutton, R., Heyman, M., Ebert, S., Fiocco, M., de Groot-Kruseman, H. A., van der Velden, V. H. J., Barbany, G., Escherich, G., Vora, A., Trahair, T., Dalla-Pozza, L., Pieters, R., Zur Stadt, U., Schmiegelow, K., Moorman, A. V., Zwaan, C. M. & den Boer, M. L., 10.2021, In: LANCET HAEMATOL. 8, 10, p. e700-e710Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Ulceration in Prolidase Deficiency: Successful Treatment with Anticoagulants
Süßmuth, K., Metze, D., Muresan, A-M., Lehmberg, K., Zur Stadt, U., Speckmann, C., Park, J. H., Marquardt, T., Oji, V. & Goerge, T., 07.01.2020, In: ACTA DERM-VENEREOL. 100, 1, p. adv00002Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional flow cytometry of monocytes for routine diagnosis of innate primary immunodeficiencies
Ammann, S., Fuchs, S., Martin-Martin, L., Castro, C. N., Spielberger, B., Klemann, C., Elling, R., Heeg, M., Speckmann, C., Hainmann, I., Kaiser-Labusch, P., Horneff, G., Thalhammer, J., Bredius, R. G., Stadt, U. Z., Lehmberg, K., Fuchs, I., von Spee-Mayer, C., Henneke, P. & Ehl, S., 01.2020, In: J ALLERGY CLIN IMMUN. 145, 1, p. 434-437.e4Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
- 2019
Characterization of novel, recurrent genomic rearrangements as sensitive MRD targets in childhood B-cell precursor ALL
Zur Stadt, U., Alawi, M., Adao, M., Indenbirken, D., Escherich, G. & Horstmann, M. A., 29.11.2019, In: BLOOD CANCER J. 9, 12, p. 96Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Results of CoALL 07-03 study childhood ALL based on combined risk assessment by in vivo and in vitro pharmacosensitivity
Schramm, F., Zur Stadt, U., Zimmermann, M., Jorch, N., Pekrun, A., Borkhardt, A., Imschweiler, T., Christiansen, H., Faber, J., Schmid, I., Feuchtinger, T., Beron, G., den Boer, M. L., Pieters, R., Horstmann, M. A., Janka-Schaub, G. E. & Escherich, G., 26.11.2019, In: Blood Adv. 3, 22, p. 3688-3699 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets
Hoell, J. I., Ginzel, S., Kuhlen, M., Kloetgen, A., Gombert, M., Fischer, U., Hein, D., Demir, S., Stanulla, M., Schrappe, M., Zur Stadt, U., Bader, P., Babor, F., Schuster, F., Strahm, B., Alten, J., Moericke, A., Escherich, G., von Stackelberg, A., Thiele, R., McHardy, A. C., Peters, C., Bornhauser, B., Bourquin, J-P., Krause, S., Enczmann, J., Meyer, L. H., Eckert, C., Borkhardt, A. & Meisel, R., 22.10.2019, In: Blood Adv. 3, 20, p. 3143-3156 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High sensitivity and clonal stability of the genomic fusion as single marker for response monitoring in ETV6-RUNX1-positive acute lymphoblastic leukemia
Hoffmann, J., Krumbholz, M., Gutiérrez, H. P., Fillies, M., Szymansky, A., Bleckmann, K., Zur Stadt, U., Köhler, R., Kuiper, R. P., Horstmann, M., von Stackelberg, A., Eckert, C. & Metzler, M., 08.2019, In: PEDIATR BLOOD CANCER. 66, 8, p. e27780Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia
Lopes, B. A., Meyer, C., Barbosa, T. C., Poubel, C. P., Mansur, M. B., Duployez, N., Bashton, M., Harrison, C. J., Zur Stadt, U., Horstmann, M., Pombo-de-Oliveira, M. S., Palmi, C., Cazzaniga, G., Venn, N. C., Sutton, R., Alonso, C. N., Tsaur, G., Gupta, S. K., Bakhshi, S., Marschalek, R. & Emerenciano, M., 05.2019, In: TRANSL ONCOL. 12, 5, p. 726-732 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Is an infectious trigger always required for primary hemophagocytic lymphohistiocytosis? Lessons from in utero and neonatal disease
Heeg, M., Ammann, S., Klemann, C., Panning, M., Falcone, V., Hengel, H., Lehmberg, K., Zur Stadt, U., Wustrau, K., Janka, G. & Ehl, S., 01.08.2018, In: PEDIATR BLOOD CANCER. 65, 11, p. e27344Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies
Cazzaniga, G., De Lorenzo, P., Alten, J., Röttgers, S., Hancock, J., Saha, V., Castor, A., Madsen, H. O., Gandemer, V., Cavé, H., Leoni, V., Köhler, R., Ferrari, G. M., Bleckmann, K., Pieters, R., van der Velden, V., Stary, J., Zuna, J., Escherich, G., Stadt, U. Z., Aricò, M., Conter, V., Schrappe, M., Valsecchi, M. G. & Biondi, A., 01.2018, In: HAEMATOLOGICA. 103, 1, p. 107-115 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Hemophagocytic lymphohistiocytosis as presenting manifestation of profound combined immunodeficiency due to an ORAI1 mutation
Klemann, C., Ammann, S., Heizmann, M., Fuchs, S., Bode, S. F., Heeg, M., Fuchs, H., Lehmberg, K., Zur Stadt, U., Roll, C., Vraetz, T., Speckmann, C., Lorenz, M. R., Schwarz, K., Rohr, J., Feske, S. & Ehl, S., 12.2017, In: J ALLERGY CLIN IMMUN. 140, 6, p. 1721-1724 4 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Effective Immunological Guidance of Genetic Analyses Including Exome Sequencing in Patients Evaluated for Hemophagocytic Lymphohistiocytosis
Ammann, S., Lehmberg, K., Zur Stadt, U., Klemann, C., Bode, S. F. N., Speckmann, C., Janka, G., Wustrau, K., Rakhmanov, M., Fuchs, I., Hennies, H. C., Ehl, S. & HLH study of the GPOH, 11.2017, In: J CLIN IMMUNOL. 37, 8, p. 770-780 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lineage switch under blinatumomab treatment of relapsed common acute lymphoblastic leukemia without MLL rearrangement
Zoghbi, A., Zur Stadt, U., Winkler, B., Müller, I. & Escherich, G., 11.2017, In: PEDIATR BLOOD CANCER. 64, 11, p. 11Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The role of constitutive activation of FMS-related tyrosine kinase-3 andmutational status in infants with-rearranged acute lymphoblastic leukemia
Fedders, H., Alsadeq, A., Schmäh, J., Vogiatzi, F., Zimmermann, M., Möricke, A., Lenk, L., Stadt, U. Z., Horstmann, M. A., Pieters, R., Schrappe, M., Stanulla, M., Cario, G. & Schewe, D. M., 11.2017, In: HAEMATOLOGICA. 102, 11, p. e438-e442Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia
Vesely, C., Frech, C., Eckert, C., Cario, G., Mecklenbräuker, A., Zur Stadt, U., Nebral, K., Kraler, F., Fischer, S., Attarbaschi, A., Schuster, M., Bock, C., Cavé, H., von Stackelberg, A., Schrappe, M., Horstmann, M. A., Mann, G., Haas, O. A. & Panzer-Grümayer, R., 07.2017, In: LEUKEMIA. 31, 7, p. 1491-1501Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary and secondary hemophagocytic lymphohistiocytosis have different patterns of T-cell activation, differentiation and repertoire
Ammann, S., Lehmberg, K., Zur Stadt, U., Janka-Schaub, G., Rensing-Ehl, A., Klemann, C., Heeg, M., Bode, S., Fuchs, I., Ehl, S. & HLH study of the GPOH, 02.2017, In: EUR J IMMUNOL. 47, 2, p. 364-373Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia
Lopes, B. A., Meyer, C., Barbosa, T. C., Stadt, U. Z., Horstmann, M., Venn, N. C., Heatley, S., White, D. L., Sutton, R., Pombo-de-Oliveira, M. S., Marschalek, R. & Emerenciano, M., 13.07.2016, In: ONCOTARGET. 7, 33, p. 53064-53073Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rapid Capture Next-Generation Sequencing in Clinical Diagnostics of Kinase Pathway Aberrations in B-Cell Precursor ALL
Stadt, U. Z., Escherich, G., Indenbirken, D., Alawi, M., Adao, M. & Horstmann, M. A., 23.03.2016, In: PEDIATR BLOOD CANCER. 63, 7, p. 1283-6Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome
Ammann, S., Schulz, A., Krägeloh-Mann, I., Dieckmann, N. M. G., Niethammer, K., Fuchs, S., Eckl, K. M., Plank, R., Werner, R., Altmüller, J., Thiele, H., Nürnberg, P., Bank, J., Strauss, A., von Bernuth, H., Zur Stadt, U., Grieve, S., Griffiths, G. M., Lehmberg, K., Hennies, H. C. & Ehl, S., 25.02.2016, In: BLOOD. 127, 8, p. 997-1006 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Malignancy-associated haemophagocytic lymphohistiocytosis in children and adolescents
Lehmberg, K., Sprekels, B., Nichols, K. E., Woessmann, W., Müller, I., Suttorp, M., Bernig, T., Beutel, K., Bode, S. F. N., Kentouche, K., Kolb, R., Längler, A., Minkov, M., Schilling, F. H., Schmid, I., Vieth, S., Ehl, S., Zur Stadt, U. & Janka, G. E., 08.2015, In: BRIT J HAEMATOL. 170, 4, p. 539-49 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Late-onset hemophagocytic lymphohistiocytosis (HLH) in an adult female with Griscelli syndrome type 2 (GS2)
Henkes, M., Finke, J., Warnatz, K., Ammann, S., Stadt, U. Z., Janka-Schaub, G. & Brugger, W., 06.2015, In: ANN HEMATOL. 94, 6, p. 1057-60 4 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia
Malinowska-Ozdowy, K., Frech, C., Schönegger, A., Eckert, C., Cazzaniga, G., Stanulla, M., Zur Stadt, U., Mecklenbräuker, A., Schuster, M., Kneidinger, D., von Stackelberg, A., Locatelli, F., Schrappe, M., Horstmann, M. A., Attarbaschi, A., Bock, C., Mann, G., Haas, O. A. & Panzer-Grümayer, R., 28.04.2015, In: LEUKEMIA. 29, 8, p. 1656-1667Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Novel Patient with Late-Onset Familial Hemophagocytic Lymphohistiocytosis with STXBP2 Mutations Presenting with Autoimmune Hepatitis, Neurological Manifestations and Infections Associated with Hypogammaglobulinemia
Esmaeilzadeh, H., Bemanian, M. H., Nabavi, M., Arshi, S., Fallahpour, M., Fuchs, I., Zur Stadt, U., Warnatz, K., Ammann, S., Ehl, S., Lehmberg, K. & Rezaei, N., 01.2015, In: J CLIN IMMUNOL. 35, 1, p. 22-25Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
A new functional assay for the diagnosis of X-linked inhibitor of apoptosis (XIAP) deficiency
Ammann, S., Elling, R., Gyrd-Hansen, M., Dückers, G., Bredius, R., Burns, S. O., Edgar, J. D. M., Worth, A., Brandau, H., Warnatz, K., Zur Stadt, U., Hasselblatt, P., Schwarz, K., Ehl, S. & Speckmann, C., 01.06.2014, In: CLIN EXP IMMUNOL. 176, 3, p. 394-400 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
The MLL recombinome of acute leukemias in 2013
Meyer, C., Hofmann, J., Burmeister, T., Gröger, D., Park, T. S., Emerenciano, M., Pombo de Oliveira, M., Renneville, A., Villarese, P., Macintyre, E., Cavé, H., Clappier, E., Mass-Malo, K., Zuna, J., Trka, J., De Braekeleer, E., De Braekeleer, M., Oh, S. H., Tsaur, G., Fechina, L., van der Velden, V. H. J., van Dongen, J. J. M., Delabesse, E., Binato, R., Silva, M. L. M., Kustanovich, A., Aleinikova, O., Harris, M. H., Lund-Aho, T., Juvonen, V., Heidenreich, O., Vormoor, J., Choi, W. W. L., Jarosova, M., Kolenova, A., Bueno, C., Menendez, P., Wehner, S., Eckert, C., Talmant, P., Tondeur, S., Lippert, E., Launay, E., Henry, C., Ballerini, P., Lapillone, H., Callanan, M. B., Cayuela, J. M., Herbaux, C., Cazzaniga, G., Kakadiya, P. M., Bohlander, S., Ahlmann, M., Choi, J. R., Gameiro, P., Lee, D. S., Krauter, J., Cornillet-Lefebvre, P., Te Kronnie, G., Schäfer, B. W., Kubetzko, S., Alonso, C. N., zur Stadt, U., Sutton, R., Venn, N. C., Izraeli, S., Trakhtenbrot, L., Madsen, H. O., Archer, P., Hancock, J., Cerveira, N., Teixeira, M. R., Lo Nigro, L., Möricke, A., Stanulla, M., Schrappe, M., Sedék, L., Szczepański, T., Zwaan, C. M., Coenen, E. A., van den Heuvel-Eibrink, M. M., Strehl, S., Dworzak, M., Panzer-Grümayer, R., Dingermann, T., Klingebiel, T. & Marschalek, R., 01.11.2013, In: LEUKEMIA. 27, 11, p. 2165-76 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clofarabine in combination with pegylated asparaginase in the frontline treatment of childhood acute lymphoblastic leukaemia: a feasibility report from the CoALL 08-09 trial
Escherich, G., Zur Stadt, U., Zimmermann, M., Horstmann, M. A. & COALL study group, 01.10.2013, In: BRIT J HAEMATOL. 163, 2, p. 240-7 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
X-linked inhibitor of apoptosis (XIAP) deficiency: the spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis
Speckmann, C., Lehmberg, K., Albert, M. H., Damgaard, R. B., Fritsch, M., Gyrd-Hansen, M., Rensing-Ehl, A., Vraetz, T., Grimbacher, B., Salzer, U., Fuchs, I., Ufheil, H., Belohradsky, B. H., Hassan, A., Cale, C. M., Elawad, M., Strahm, B., Schibli, S., Lauten, M., Kohl, M., Meerpohl, J. J., Rodeck, B., Kolb, R., Eberl, W., Soerensen, J., von Bernuth, H., Lorenz, M., Schwarz, K., zur Stadt, U. & Ehl, S., 01.10.2013, In: CLIN IMMUNOL. 149, 1, p. 133-41 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling
Damgaard, R. B., Fiil, B. K., Speckmann, C., Yabal, M., zur Stadt, U., Bekker-Jensen, S., Jost, P. J., Ehl, S., Mailand, N. & Gyrd-Hansen, M., 01.08.2013, In: EMBO MOL MED. 5, 8, p. 1278-95 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Persistent defective membrane trafficking in epithelial cells of patients with familial hemophagocytic lymphohistiocytosis type 5 due to STXBP2/MUNC18-2 mutations
Stepensky, P., Bartram, J., Barth, T. F., Lehmberg, K., Walther, P., Amann, K., Philips, A. D., Beringer, O., zur Stadt, U., Schulz, A., Amrolia, P., Weintraub, M., Debatin, K-M., Hoenig, M. & Posovszky, C., 01.07.2013, In: PEDIATR BLOOD CANCER. 60, 7, p. 1215-22 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2
Jessen, B., Bode, S. F. N., Ammann, S., Chakravorty, S., Davies, G., Diestelhorst, J., Frei-Jones, M., Gahl, W. A., Gochuico, B. R., Griese, M., Griffiths, G., Janka-Schaub, G., Klein, C., Kögl, T., Kurnik, K., Lehmberg, K., Maul-Pavicic, A., Mumford, A. D., Pace, D., Parvaneh, N., Rezaei, N., de Saint Basile, G., Schmitt-Graeff, A., Schwarz, K., Karasu, G. T., Zieger, B., zur Stadt, U., Aichele, P. & Ehl, S., 11.04.2013, In: BLOOD. 121, 15, p. 2943-51 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hemophagocytic lymphohistiocytosis in syntaxin-11-deficient mice: T-cell exhaustion limits fatal disease
Kögl, T., Müller, J., Jessen, B., Schmitt-Graeff, A., Janka-Schaub, G., Ehl, S., zur Stadt, U. & Aichele, P., 24.01.2013, In: BLOOD. 121, 4, p. 604-13 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Refinement of IKZF1 recombination hotspots in pediatric BCP-ALL patients.
Meyer, C., Zur Stadt, U., Escherich, G., Hofmann, J., Binato, R., Barbosa, T. D. C., Emerenciano, M., Pombo-de-Oliveira, M. S., Horstmann, M. & Marschalek, R., 2013, In: AM J BLOOD RES. 3, 2, p. 165-173 9 p., 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Syntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulation.
D'Orlando, O., Zhao, F., Kasper, B., Orinska, Z., Müller, J., Hermans-Borgmeyer, I., Griffiths, G. M., Zur Stadt, U. & Bulfone-Paus, S., 2013, In: EUR J IMMUNOL. 43, 1, p. 194-208 15 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
Distinct mutations in STXBP2 are associated with variable clinical presentations in patients with familial hemophagocytic lymphohistiocytosis type 5 (FHL5)
Pagel, J., Beutel, K., Lehmberg, K., Koch, F., Maul-Pavicic, A., Rohlfs, A-K., Al-Jefri, A., Beier, R., Lilian, B. O., Ehlert, K., Gross-Wieltsch, U., Jorch, N., Kremens, B., Pekrun, A., Sparber-Sauer, M., Mejstrikova, E., Wawer, A., Ehl, S., Zur Stadt, U. & Janka-Schaub, G., 21.06.2012, In: BLOOD. 119, 25, p. 6016-6024 9 p., 25.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes.
Bryceson, Y. T., Pende, D., Maul-Pavicic, A., Gilmour, K. C., Ufheil, H., Vraetz, T., Chiang, S. C., Marcenaro, S., Meazza, R., Bondzio, I., Walshe, D., Janka-Schaub, G., Lehmberg, K., Beutel, K., Zur Stadt, U., Binder, N., Arico, M., Moretta, L., Henter, J-I. & Ehl, S., 2012, In: BLOOD. 119, 12, p. 2754-2763 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fatal EBV infection and variable clinical manifestations in an XLP-1 pedigree - rapid diagnosis of primary immunodeficiencies may save lives.
Sperl, D., Benesch, M., Urban, C., Lackner, H., Sovinz, P., Speicher, M. R., Uhrig, S., Schwarzbraun, T., Schwinger, W., Zur Stadt, U., Beutel, K., Janka-Schaub, G., Scarpatetti, M. & Seidel, M. G., 2012, In: KLIN PADIATR. 224, 6, p. 386-389 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice.
Terziyska, N., Catarina, C. A., Groiss, V., Schneider, K., Farkasova, K., Ogris, M., Wagner, E., Ehrhardt, H., Brentjens, R. J., Zur Stadt, U., Horstmann, M., Quintanilla-Martinez, L. & Jeremias, I., 2012, In: PLOS ONE. 7, 12, p. 52798 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantification of minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL) using amplicon-fusion-site polymerase chain reaction (AFS-PCR).
Weber, A., Taube, S., Zur Stadt, U., Horstmann, M., Krohn, K., Bradtke, J., Teigler-Schlegel, A., Leiblein, S. & Christiansen, H., 2012, In: EXP HEMATOL ONCOL. 1, 1, p. 33 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis.
Bode, S. F., Lehmberg, K., Maul-Pavicic, A., Vraetz, T., Janka-Schaub, G., Zur Stadt, U. & Ehl, S., 2012, In: ARTHRITIS RES THER. 14, 3, p. 213 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Genotype-phenotype study of familial haemophagocytic lymphohistiocytosis type 3.
Sieni, E., Cetica, V., Santoro, A., Beutel, K., Mastrodicasa, E., Meeths, M., Ciambotti, B., Brugnolo, F., Zur Stadt, U., Pende, D., Moretta, L., Griffiths, G. M., Henter, J-I., Janka-Schaub, G. & Aricò, M., 2011, In: J MED GENET. 48, 5, p. 343-352 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome.
Jessen, B., Maul-Pavicic, A., Ufheil, H., Vraetz, T., Enders, A., Lehmberg, K., Längler, A., Gross-Wieltsch, U., Bay, A., Kaya, Z., Bryceson, Y. T., Koscielniak, E., Badawy, S., Davies, G., Hufnagel, M., Schmitt-Graeff, A., Aichele, P., Zur Stadt, U., Schwarz, K. & Ehl, S., 2011, In: BLOOD. 118, 17, p. 4620-4629 17.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97).
Escherich, G., Troeger, A. F., Gobel, U., Graubner, U., Pekrun, A., Jorch, N., Kaspers, G., Zimmermann, M., Zur Stadt, U., Kazemir, K., Pieters, R., Horstmann, M., Denboer, M. L. & Janka-Schaub, G., 2011, In: HAEMATOLOGICA. 96, 6, p. 854-862 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases
Rohr, J., Beutel, K., Maul-Pavicic, A., Vraetz, T., Thiel, J., Warnatz, K., Bondzio, I., Gross-Wieltsch, U., Schündeln, M., Schütz, B., Woessmann, W., Groll, A. H., Strahm, B., Pagel, J., Speckmann, C., Janka-Schaub, G., Griffiths, G., Schwarz, K., Zur Stadt, U. & Ehl, S., 12.2010, In: HAEMATOLOGICA. 95, 12, p. 2080-2087 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia.
Müller-Tidow, C., Klein, H-U., Hascher, A., Isken, F., Tickenbrock, L., Thoennissen, N., Agrawal-Singh, S., Tschanter, P., Disselhoff, C., Wang, Y., Becker, A., Thiede, C., Ehninger, G., Zur Stadt, U., Koschmieder, S., Seidl, M., Müller, F. U., Schmitz, W., Schlenke, P., McClelland, M., Berdel, W. E., Dugas, M., Serve, H. & Leukemia, S. A., 2010, In: BLOOD. 116, 18, p. 3564-3571 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
STXBP2 mutations in children with familial haemophagocytic lymphohistiocytosis type 5.
Cetica, V., Santoro, A., Gilmour, K. C., Sieni, E., Beutel, K., Pende, D., Marcenaro, S., Koch, F., Grieve, S., Wheeler, R., Zhao, F., Zur Stadt, U., Griffiths, G. M. & Aricò, M., 2010, In: J MED GENET. 47, 9, p. 595-600 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11
zur Stadt, U., Rohr, J., Seifert, W., Koch, F., Grieve, S., Pagel, J., Strauss, J., Kasper, B., Nürnberg, G., Becker, C., Maul-Pavicic, A., Beutel, K., Janka, G., Griffiths, G., Ehl, S. & Hennies, H. C., 10.2009, In: AM J HUM GENET. 85, 4, p. 482-492 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review