Nadja Bork
Publications
- 2023
Role of Phosphodiesterase 1 in the Regulation of Real-Time cGMP Levels and Contractility in Adult Mouse Cardiomyocytes
Bork, N. I., Subramanian, H., Kurelic, R., Nikolaev, V. O. & Rybalkin, S. D., 03.12.2023, In: CELLS-BASEL. 12, 23, 2759.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CRISPR/Cas9 Knock-Out in Primary Neonatal and Adult Cardiomyocytes Reveals Distinct cAMP Dynamics Regulation by Various PDE2A and PDE3A Isoforms
Skryabin, E. B., De Jong, K. A., Subramanian, H., Bork, N. I., Froese, A., Skryabin, B. V. & Nikolaev, V. O., 04.06.2023, In: CELLS-BASEL. 12, 11, 1543.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Compartmentation of cGMP Signaling in Induced Pluripotent Stem Cell Derived Cardiomyocytes during Prolonged Culture
Faleeva, M., Diakonov, I., Srivastava, P., Ramuz, M., Calamera, G., Andressen, K. W., Bork, N., Tsansizi, L., Cosson, M-V., Bernardo, A. S., Nikolaev, V. & Gorelik, J., 17.10.2022, In: CELLS-BASEL. 11, 20, 3257.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Skeletal muscle derived Musclin protects the heart during pathological overload
Szaroszyk, M., Kattih, B., Martin-Garrido, A., Trogisch, F. A., Dittrich, G. M., Grund, A., Abouissa, A., Derlin, K., Meier, M., Holler, T., Korf-Klingebiel, M., Völker, K., Garfias Macedo, T., Pablo Tortola, C., Boschmann, M., Huang, N., Froese, N., Zwadlo, C., Malek Mohammadi, M., Luo, X., Wagner, M., Cordero, J., Geffers, R., Batkai, S., Thum, T., Bork, N., Nikolaev, V. O., Müller, O. J., Katus, H. A., El-Armouche, A., Kraft, T., Springer, J., Dobreva, G., Wollert, K. C., Fielitz, J., von Haehling, S., Kuhn, M., Bauersachs, J. & Heineke, J., 10.01.2022, In: NAT COMMUN. 13, 1, 149.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia
Bork, N., Kuret, A., Cruz Santos, M., Molina, C., Reiter, B., Reichenspurner, H., Friebe, A., Skryabin, B. V., Rozhdestvensky, T. S., Kuhn, M., Lukowski, R. & Nikolaev, V., 01.12.2021, In: REDOX BIOL. 48, 102179.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mapping genetic changes in the cAMP-signaling cascade in human atria
Garnier, A., Bork, N., Jacquet, E., Zipfel, S., Muñoz-Guijosa, C., Baczkó, I., Reichenspurner, H., Donzeau-Gouge, P., Maier, L. S., Dobrev, D., Girdauskas, E., Nikolaev, V., Fischmeister, R. & Molina, C., 22.02.2021, In: J MOL CELL CARDIOL. 155, p. 10-20Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Sacubitrilat reduces pro-arrhythmogenic sarcoplasmic reticulum Ca2+ leak in human ventricular cardiomyocytes of patients with end-stage heart failure
Eiringhaus, J., Wünsche, C. M., Tirilomis, P., Herting, J., Bork, N., Nikolaev, V. O., Hasenfuss, G., Sossalla, S. & Fischer, T. H., 10.2020, In: ESC HEART FAIL. 7, 5, p. 2992-3002 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes
Stathopoulou, K., Schobesberger, S., Bork, N. I., Sprenger, J. U., Perera, R. K., Sotoud, H., Geertz, B., David, J-P., Christ, T., Nikolaev, V. O. & Cuello, F., 11.2019, In: CELL SIGNAL. 63, p. 109362Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
cGMP signalling in cardiomyocyte microdomains
Bork, N. I., Molina, C. E. & Nikolaev, V. O., 31.10.2019, In: BIOCHEM SOC T. 47, 5, p. 1327-1339 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2018
Membrane-Permeable Octanoyloxybenzyl-Masked cNMPs As Novel Tools for Non-Invasive Cell Assays.
Ruthenbeck, A., Marangoni, E., Diercks, B-P., Krüger, A., Froese, A., Bork, N., Nikolaev, V., Guse, A. & Meier, C., 13.11.2018, In: MOLECULES. 23, 11, p. E2960Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System
Jungen, C., Scherschel, K., Bork, N. I., Kuklik, P., Eickholt, C., Kniep, H., Klatt, N., Willems, S., Nikolaev, V. O. & Meyer, C., 22.05.2018, In: JOVE-J VIS EXP. 135Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in βAR-cAMP Responsiveness in Murine Hearts
Wright, P. T., Bhogal, N. K., Diakonov, I., Pannell, L. M. K., Perera, R. K., Bork, N. I., Schobesberger, S., Lucarelli, C., Faggian, G., Alvarez-Laviada, A., Zaccolo, M., Kamp, T. J., Balijepalli, R. C., Lyon, A. R., Harding, S. E., Nikolaev, V. O. & Gorelik, J., 10.04.2018, In: CELL REP. 23, 2, p. 459-469 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
cGMP Signaling in the Cardiovascular System-The Role of Compartmentation and Its Live Cell Imaging
Bork, N. I. & Nikolaev, V. O., 10.03.2018, In: INT J MOL SCI. 19, 3, p. 801Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2017
cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels
Frankenreiter, S., Bednarczyk, P., Kniess, A., Bork, N. I., Straubinger, J., Koprowski, P., Wrzosek, A., Mohr, E., Logan, A., Murphy, M. P., Gawaz, M., Krieg, T., Szewczyk, A., Nikolaev, V. O., Ruth, P. & Lukowski, R., 12.12.2017, In: CIRCULATION. 136, 24, p. 2337-2355 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4
Perera, R. K., Fischer, T. H., Wagner, M., Dewenter, M., Vettel, C., Bork, N. I., Maier, L. S., Conti, M., Wess, J., El-Armouche, A., Hasenfuß, G. & Nikolaev, V. O., 09.11.2017, In: SCI REP-UK. 7, 1, p. 15222Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias
Jungen, C., Scherschel, K., Eickholt, C., Kuklik, P., Klatt, N., Bork, N., Salzbrunn, T., Alken, F., Angendohr, S., Klene, C., Mester, J., Klöcker, N., Veldkamp, M. W., Schumacher, U., Willems, S., Nikolaev, V. O. & Meyer, C., 27.01.2017, In: NAT COMMUN. 8, 14155.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Receptor-Cyclic Nucleotide Microdomains in the Heart
Bork, N. & Nikolaev, V., 2017, Microdomains in the Cardiovascular System. Springer, p. 3-15Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2016
Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET
Sprenger, J. U., Bork, N. I., Herting, J., Fischer, T. H. & Nikolaev, V. O., 2016, In: PLOS ONE. 11, 12, p. e0167974Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review