Nadja Bork

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Publications

  1. 2023
  2. Role of Phosphodiesterase 1 in the Regulation of Real-Time cGMP Levels and Contractility in Adult Mouse Cardiomyocytes

    Bork, N. I., Subramanian, H., Kurelic, R., Nikolaev, V. O. & Rybalkin, S. D., 03.12.2023, In: CELLS-BASEL. 12, 23, 2759.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. CRISPR/Cas9 Knock-Out in Primary Neonatal and Adult Cardiomyocytes Reveals Distinct cAMP Dynamics Regulation by Various PDE2A and PDE3A Isoforms

    Skryabin, E. B., De Jong, K. A., Subramanian, H., Bork, N. I., Froese, A., Skryabin, B. V. & Nikolaev, V. O., 04.06.2023, In: CELLS-BASEL. 12, 11, 1543.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. 2022
  5. Compartmentation of cGMP Signaling in Induced Pluripotent Stem Cell Derived Cardiomyocytes during Prolonged Culture

    Faleeva, M., Diakonov, I., Srivastava, P., Ramuz, M., Calamera, G., Andressen, K. W., Bork, N., Tsansizi, L., Cosson, M-V., Bernardo, A. S., Nikolaev, V. & Gorelik, J., 17.10.2022, In: CELLS-BASEL. 11, 20, 3257.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Skeletal muscle derived Musclin protects the heart during pathological overload

    Szaroszyk, M., Kattih, B., Martin-Garrido, A., Trogisch, F. A., Dittrich, G. M., Grund, A., Abouissa, A., Derlin, K., Meier, M., Holler, T., Korf-Klingebiel, M., Völker, K., Garfias Macedo, T., Pablo Tortola, C., Boschmann, M., Huang, N., Froese, N., Zwadlo, C., Malek Mohammadi, M., Luo, X., Wagner, M., Cordero, J., Geffers, R., Batkai, S., Thum, T., Bork, N., Nikolaev, V. O., Müller, O. J., Katus, H. A., El-Armouche, A., Kraft, T., Springer, J., Dobreva, G., Wollert, K. C., Fielitz, J., von Haehling, S., Kuhn, M., Bauersachs, J. & Heineke, J., 10.01.2022, In: NAT COMMUN. 13, 1, 149.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. 2021
  8. Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia

    Bork, N., Kuret, A., Cruz Santos, M., Molina, C., Reiter, B., Reichenspurner, H., Friebe, A., Skryabin, B. V., Rozhdestvensky, T. S., Kuhn, M., Lukowski, R. & Nikolaev, V., 01.12.2021, In: REDOX BIOL. 48, 102179.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Mapping genetic changes in the cAMP-signaling cascade in human atria

    Garnier, A., Bork, N., Jacquet, E., Zipfel, S., Muñoz-Guijosa, C., Baczkó, I., Reichenspurner, H., Donzeau-Gouge, P., Maier, L. S., Dobrev, D., Girdauskas, E., Nikolaev, V., Fischmeister, R. & Molina, C., 22.02.2021, In: J MOL CELL CARDIOL. 155, p. 10-20

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. 2020
  11. Sacubitrilat reduces pro-arrhythmogenic sarcoplasmic reticulum Ca2+ leak in human ventricular cardiomyocytes of patients with end-stage heart failure

    Eiringhaus, J., Wünsche, C. M., Tirilomis, P., Herting, J., Bork, N., Nikolaev, V. O., Hasenfuss, G., Sossalla, S. & Fischer, T. H., 10.2020, In: ESC HEART FAIL. 7, 5, p. 2992-3002 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. 2019
  13. Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes

    Stathopoulou, K., Schobesberger, S., Bork, N. I., Sprenger, J. U., Perera, R. K., Sotoud, H., Geertz, B., David, J-P., Christ, T., Nikolaev, V. O. & Cuello, F., 11.2019, In: CELL SIGNAL. 63, p. 109362

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. cGMP signalling in cardiomyocyte microdomains

    Bork, N. I., Molina, C. E. & Nikolaev, V. O., 31.10.2019, In: BIOCHEM SOC T. 47, 5, p. 1327-1339 13 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  15. 2018
  16. Membrane-Permeable Octanoyloxybenzyl-Masked cNMPs As Novel Tools for Non-Invasive Cell Assays.

    Ruthenbeck, A., Marangoni, E., Diercks, B-P., Krüger, A., Froese, A., Bork, N., Nikolaev, V., Guse, A. & Meier, C., 13.11.2018, In: MOLECULES. 23, 11, p. E2960

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System

    Jungen, C., Scherschel, K., Bork, N. I., Kuklik, P., Eickholt, C., Kniep, H., Klatt, N., Willems, S., Nikolaev, V. O. & Meyer, C., 22.05.2018, In: JOVE-J VIS EXP. 135

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in βAR-cAMP Responsiveness in Murine Hearts

    Wright, P. T., Bhogal, N. K., Diakonov, I., Pannell, L. M. K., Perera, R. K., Bork, N. I., Schobesberger, S., Lucarelli, C., Faggian, G., Alvarez-Laviada, A., Zaccolo, M., Kamp, T. J., Balijepalli, R. C., Lyon, A. R., Harding, S. E., Nikolaev, V. O. & Gorelik, J., 10.04.2018, In: CELL REP. 23, 2, p. 459-469 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. cGMP Signaling in the Cardiovascular System-The Role of Compartmentation and Its Live Cell Imaging

    Bork, N. I. & Nikolaev, V. O., 10.03.2018, In: INT J MOL SCI. 19, 3, p. 801

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  20. 2017
  21. cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels

    Frankenreiter, S., Bednarczyk, P., Kniess, A., Bork, N. I., Straubinger, J., Koprowski, P., Wrzosek, A., Mohr, E., Logan, A., Murphy, M. P., Gawaz, M., Krieg, T., Szewczyk, A., Nikolaev, V. O., Ruth, P. & Lukowski, R., 12.12.2017, In: CIRCULATION. 136, 24, p. 2337-2355 19 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4

    Perera, R. K., Fischer, T. H., Wagner, M., Dewenter, M., Vettel, C., Bork, N. I., Maier, L. S., Conti, M., Wess, J., El-Armouche, A., Hasenfuß, G. & Nikolaev, V. O., 09.11.2017, In: SCI REP-UK. 7, 1, p. 15222

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias

    Jungen, C., Scherschel, K., Eickholt, C., Kuklik, P., Klatt, N., Bork, N., Salzbrunn, T., Alken, F., Angendohr, S., Klene, C., Mester, J., Klöcker, N., Veldkamp, M. W., Schumacher, U., Willems, S., Nikolaev, V. O. & Meyer, C., 27.01.2017, In: NAT COMMUN. 8, 14155.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Receptor-Cyclic Nucleotide Microdomains in the Heart

    Bork, N. & Nikolaev, V., 2017, Microdomains in the Cardiovascular System. Springer, p. 3-15

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  25. 2016
  26. Interactions of Calcium Fluctuations during Cardiomyocyte Contraction with Real-Time cAMP Dynamics Detected by FRET

    Sprenger, J. U., Bork, N. I., Herting, J., Fischer, T. H. & Nikolaev, V. O., 2016, In: PLOS ONE. 11, 12, p. e0167974

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review