Prof.Dr.rer.nat ID: 30923
Maura Dandri-Petersen
Publications
- 2023
Potent broadly neutralizing antibody VIR-3434 controls hepatitis B and D virus infection and reduces HBsAg in humanized mice
Lempp, F. A., Volz, T., Cameroni, E., Benigni, F., Zhou, J., Rosen, L. E., Noack, J., Zatta, F., Kaiser, H., Bianchi, S., Lombardo, G., Jaconi, S., Vincenzetti, L., Imam, H., Soriaga, L. B., Passini, N., Belnap, D. M., Schulze, A., Lütgehetmann, M., Telenti, A., Cathcart, A. L., Snell, G., Purcell, L. A., Hebner, C. M., Urban, S., Dandri, M., Corti, D. & Schmid, M. A., 11.2023, In: J HEPATOL. 79, 5, p. 1129-1138 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantification of the hepatitis B virus cccDNA: evidence-based guidelines for monitoring the key obstacle of HBV cure
Allweiss, L., Testoni, B., Yu, M., Lucifora, J., Ko, C., Qu, B., Lütgehetmann, M., Guo, H., Urban, S., Fletcher, S. P., Protzer, U., Levrero, M., Zoulim, F. & Dandri-Petersen, M., 05.2023, In: GUT. 72, 5, p. 972-983 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Strain-specific responsiveness of hepatitis D virus to interferon-alpha treatment
Giersch, K., Perez-Gonzalez, P., Hendricks, L., Goldmann, N., Kolbe, J., Hermanussen, L., Bockmann, J-H., Volz, T., Volmari, A., Allweiss, L., Petersen, J., Glebe, D., Lütgehetmann, M. & Dandri, M., 04.2023, In: JHEP REP. 5, 4, p. 100673Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Safety and efficacy of bulevirtide in combination with tenofovir disoproxil fumarate in patients with hepatitis B virus and hepatitis D virus coinfection (MYR202): a multicentre, randomised, parallel-group, open-label, phase 2 trial
Wedemeyer, H., Schöneweis, K., Bogomolov, P., Blank, A., Voronkova, N., Stepanova, T., Sagalova, O., Chulanov, V., Osipenko, M., Morozov, V., Geyvandova, N., Sleptsova, S., Bakulin, I. G., Khaertynova, I., Rusanova, M., Pathil, A., Merle, U., Bremer, B., Allweiss, L., Lempp, F. A., Port, K., Haag, M., Schwab, M., Zur Wiesch, J. S., Cornberg, M., Haefeli, W. E., Dandri, M., Alexandrov, A. & Urban, S., 01.2023, In: LANCET INFECT DIS. 23, 1, p. 117-129 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Non-organ-specific autoantibodies with unspecific patterns are a frequent para-infectious feature of chronic hepatitis D
Hermanussen, L., Lampalzer, S., Bockmann, J-H., Ziegler, A. E., Piecha, F., Dandri, M., Pischke, S., Haag, F., Lohse, A. W., Lütgehetmann, M., Weiler-Normann, C. & Zur Wiesch, J. S., 2023, In: FRONT MED-LAUSANNE. 10, p. 1169096Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook
Kramvis, A., Chang, K-M., Dandri, M., Farci, P., Glebe, D., Hu, J., Janssen, H. L. A., Lau, D. T. Y., Penicaud, C., Pollicino, T., Testoni, B., Van Bömmel, F., Andrisani, O., Beumont-Mauviel, M., Block, T. M., Chan, H. L. Y., Cloherty, G. A., Delaney, W. E., Geretti, A. M., Gehring, A., Jackson, K., Lenz, O., Maini, M. K., Miller, V., Protzer, U., Yang, J. C., Yuen, M-F., Zoulim, F. & Revill, P. A., 11.2022, In: NAT REV GASTRO HEPAT. 19, 11, p. 727-745 19 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
The hepatitis delta virus and chronic hepatitis D
Dandri, M., Volmari, A. & Lütgehetmann, M., 11.2022, In: J HEPATOL. 77, 5, p. 1448-1450 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo
Allweiss, L., Giersch, K., Pirosu, A., Volz, T., Muench, R. C., Beran, R. K., Urban, S., Javanbakht, H., Fletcher, S. P., Lütgehetmann, M. & Dandri-Petersen, M., 02.2022, In: GUT. 71, 2, p. 372-381 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Clinical establishment of a laboratory developed quantitative HDV PCR assay on the cobas6800 high-throughput system
Pflüger, L. S., Nörz, D., Volz, T., Giersch, K., Giese, A., Goldmann, N., Glebe, D., Bockmann, J-H., Pfefferle, S., Dandri, M., Schulze Zur Wiesch, J. & Lütgehetmann, M., 12.2021, In: JHEP REP. 3, 6, 100356.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Innate immunity in hepatitis B and D virus infection: consequences for viral persistence, inflammation, and T cell recognition
Dandri, M., Bertoletti, A. & Lütgehetmann, M., 08.2021, In: SEMIN IMMUNOPATHOL. 43, 4, p. 535-548 14 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
High Rates of Liver Cirrhosis and Hepatocellular Carcinoma in Chronic Hepatitis B Patients with Metabolic and Cardiovascular Comorbidities
Bockmann, J-H., Kohsar, M., Murray, J. M., Hamed, V., Dandri-Petersen, M., Lüth, S., Lohse, A. W. & Schulze-Zur-Wiesch, J., 30.04.2021, In: MICROORGANISMS. 9, 5, 968.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In Vivo Models of HDV Infection: Is Humanizing NTCP Enough?
Giersch, K. & Dandri, M., 31.03.2021, In: VIRUSES-BASEL. 13, 4, p. 588Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Chromatin Extraction from Frozen Chimeric Liver Tissue for Chromatin Immunoprecipitation Analysis
Pirosu, A., Allweiss, L. & Dandri-Petersen, M., 23.03.2021, In: JOVE-J VIS EXP. 2021, 169, e62179.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Murine hepatocytes do not support persistence of Hepatitis D Virus mono-infection in vivo
Giersch, K., Hermanussen, L., Volz, T., Kah, J., Allweiss, L., Casey, J., Sureau, C., Dandri, M. & Lütgehetmann, M., 02.2021, In: LIVER INT. 41, 2, p. 410-419 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Strong Replication Interference Between Hepatitis Delta Viruses in Human Liver Chimeric Mice
Giersch, K., Hermanussen, L., Volz, T., Volmari, A., Allweiss, L., Sureau, C., Casey, J., Huang, J., Fischer, N., Lütgehetmann, M. & Dandri, M., 2021, In: FRONT MICROBIOL. 12, p. 671466Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Neuropathology of patients with COVID-19 in Germany: a post-mortem case series
Matschke, J., Lütgehetmann, M., Hagel, C., Sperhake, J. P., Schröder, A. S., Edler, C., Mushumba, H., Fitzek, A., Allweiss, L., Dandri, M., Dottermusch, M., Heinemann, A., Pfefferle, S., Schwabenland, M., Sumner Magruder, D., Bonn, S., Prinz, M., Gerloff, C., Püschel, K., Krasemann, S., Aepfelbacher, M. & Glatzel, M., 11.2020, In: LANCET NEUROL. 19, 11, p. 919-929 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel method to precisely quantify hepatitis B virus covalently closed circular (ccc)DNA formation and maintenance
Tu, T., Zehnder, B., Qu, B., Ni, Y., Main, N., Allweiss, L., Dandri, M., Shackel, N., George, J. & Urban, S., 09.2020, In: ANTIVIR RES. 181, p. 104865Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatitis B Virus Particles Activate Toll-Like Receptor 2 Signaling Initially Upon Infection of Primary Human Hepatocytes
Zhang, Z., Trippler, M., Real, C. I., Werner, M., Luo, X., Schefczyk, S., Kemper, T., Anastasiou, O. E., Ladiges, Y., Treckmann, J., Paul, A., Baba, H. A., Allweiss, L., Dandri, M., Gerken, G., Wedemeyer, H., Schlaak, J. F., Lu, M. & Broering, R., 09.2020, In: HEPATOLOGY. 72, 3, p. 829-844 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatitis Delta Virus Acts as an Immunogenic Adjuvant in Hepatitis B Virus-Infected Hepatocytes
Tham, C. Y. L., Kah, J., Tan, A. T., Volz, T., Chia, A., Giersch, K., Ladiges, Y., Loglio, A., Borghi, M., Sureau, C., Lampertico, P., Lütgehetmann, M., Dandri-Petersen, M. & Bertoletti, A., 21.07.2020, In: CELL REP MED. 1, 4, p. 100060Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epigenetic modulation in chronic hepatitis B virus infection
Dandri, M., 04.2020, In: SEMIN IMMUNOPATHOL. 42, 2, p. 173-185 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
High rates of cirrhosis and severe clinical events in patients with HBV/HDV co-infection:longitudinal analysis of a German cohort:longitudinal analysis of a German cohort
Bockmann, J-H., Grube, M., Hamed, V., von Felden, J., Landahl, J., Wehmeyer, M., Giersch, K., Hall, M. T., Murray, J. M., Dandri, M., Lüth, S., Lohse, A. W., Lütgehetmann, M. & Schulze Zur Wiesch, J., 30.01.2020, In: BMC GASTROENTEROL. 20, 1, p. 24Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
cccDNA Maintenance in Chronic Hepatitis B - Targeting the Matrix of Viral Replication
Dandri, M. & Petersen, J., 2020, In: INFECT DRUG RESIST. 13, p. 3873-3886 14 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2019
Comparative Analysis of the Antiviral Effects Mediated by Type I and III Interferons in Hepatitis B Virus-Infected Hepatocytes
Bockmann, J-H., Stadler, D., Xia, Y., Ko, C., Wettengel, J. M., Schulze Zur Wiesch, J., Dandri, M. & Protzer, U., 19.07.2019, In: J INFECT DIS. 220, 4, p. 567-577 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A global scientific strategy to cure hepatitis B
ICE-HBV Working Groups, 07.2019, In: LANCET GASTROENTEROL. 4, 7, p. 545-558 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
T cell receptor grafting allows virological control of Hepatitis B virus infection
Wisskirchen, K., Kah, J., Malo, A., Asen, T., Volz, T., Allweiss, L., Wettengel, J. M., Lütgehetmann, M., Urban, S., Bauer, T., Dandri, M. & Protzer, U., 30.04.2019, In: J CLIN INVEST. 129, 7, p. 2932-2945 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo
Giersch, K., Bhadra, O. D., Volz, T., Allweiss, L., Riecken, K., Fehse, B., Lohse, A. W., Petersen, J., Sureau, C., Urban, S., Dandri, M. & Lütgehetmann, M., 01.2019, In: GUT. 68, 1, p. 150-157 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD49a Expression Identifies a Subset of Intrahepatic Macrophages in Humans
Martrus, G., Goebels, H., Langeneckert, A. E., Kah, J., Flomm, F., Ziegler, A. E., Niehrs, A., Löbl, S. M., Russu, K., Hess, L. U., Salzberger, W., Poch, T., Nashan, B., Schramm, C., Oldhafer, K. J., Dandri, M., Koch, M., Lunemann, S. & Altfeld, M., 2019, In: FRONT IMMUNOL. 10, p. 1247Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Down-regulation of cell membrane localized NTCP expression in proliferating hepatocytes prevents hepatitis B virus infection
Yan, Y., Allweiss, L., Yang, D., Kang, J., Wang, J., Qian, X., Zhang, T., Liu, H., Wang, L., Liu, S., Sui, J., Chen, X., Dandri, M., Zhao, J. & Lu, F., 2019, In: EMERG MICROBES INFEC. 8, 1, p. 879-894 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Interactions Between KIR3DS1 and HLA-F Activate Natural Killer Cells to Control HCV Replication in Cell Culture
Lunemann, S., Schöbel, A., Kah, J., Fittje, P., Hölzemer, A., Langeneckert, A. E., Hess, L. U., Poch, T., Martrus, G., Garcia-Beltran, W. F., Körner, C., Ziegler, A. E., Richert, L., Oldhafer, K. J., Schulze Zur Wiesch, J., Schramm, C., Dandri, M., Herker, E. & Altfeld, M., 11.2018, In: GASTROENTEROLOGY. 155, 5, p. 1366-1371Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nonlytic Lymphocytes Engineered to Express Virus-Specific T-Cell Receptors Limit HBV Infection by Activating APOBEC3
Koh, S., Kah, J., Tham, C. Y. L., Yang, N., Ceccarello, E., Chia, A., Chen, M., Khakpoor, A., Pavesi, A., Tan, A. T., Dandri, M. & Bertoletti, A., 07.2018, In: GASTROENTEROLOGY. 155, 1, p. 180-193.e6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A Novel Orally Available Small Molecule That Inhibits Hepatitis B Virus Expression
Mueller, H., Wildum, S., Luangsay, S., Walther, J., Lopez, A., Tropberger, P., Ottaviani, G., Lu, W., John Parrott, N., Zhang, J. D., Schmucki, R., Racek, T., Hoflack, J-C., Kueng, E., Point, F., Zhou, X., Steiner, G., Lütgehetmann, M., Rapp, G., Volz, T., Dandri, M., Yang, S., Young, J. A. T. & Javanbakht, H., 03.2018, In: J HEPATOL. 68, 3, p. 412-420 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo
Allweiss, L., Volz, T., Giersch, K., Kah, J., Raffa, G., Petersen, J., Lohse, A. W., Beninati, C., Pollicino, T., Urban, S., Lütgehetmann, M. & Dandri, M., 03.2018, In: GUT. 67, 3, p. 542-552 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficacy of NVR 3-778, Alone and in Combination With Pegylated Interferon, vs Entecavir in uPA/SCID Mice With Humanized Livers and HBV Infection
Klumpp, K., Shimada, T., Allweiss, L., Volz, T., Lütgehetmann, M., Hartman, G., Flores, O. A., Lam, A. M. & Dandri-Petersen, M., 02.2018, In: GASTROENTEROLOGY. 154, 3, p. 652-662.e8Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Multi-color RGB marking enables clonality assessment of liver tumors in a murine xenograft model
Thomaschewski, M., Riecken, K., Unrau, L., Volz, T., Cornils, K., Ittrich, H., Heim, D., Wege, H., Akgün, E., Lütgehetmann, M., Dieckhoff, J., Köpke, M., Dandri, M., Benten, D. & Fehse, B., 29.12.2017, In: ONCOTARGET. 8, 70, p. 115582-115595 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection
Kah, J., Koh, S., Volz, T., Ceccarello, E., Allweiss, L., Lütgehetmann, M., Bertoletti, A. & Dandri, M., 01.08.2017, In: J CLIN INVEST. 127, 8, p. 3177-3188 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Heme oxygenase-1 polymorphisms can affect HCV replication and treatment responses with different efficacy in humanized mice
Kah, J., Volz, T., Lütgehetmann, M., Groth, A., Lohse, A. W., Tiegs, G., Sass, G. & Dandri-Petersen, M., 08.2017, In: LIVER INT. 37, 8, p. 1128-1137Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis
Worthmann, A., John, C., Rühlemann, M. C., Baguhl, M., Heinsen, F-A., Schaltenberg, N., Heine, M., Schlein, C., Evangelakos, I., Mineo, C., Fischer, M., Dandri, M., Kremoser, C., Scheja, L., Franke, A., Shaul, P. W. & Heeren, J., 07.2017, In: NAT MED. 23, 7, p. 839-849 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Role of cccDNA in HBV Maintenance
Allweiss, L. & Dandri, M., 21.06.2017, In: VIRUSES-BASEL. 9, 6Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Both interferon alpha and lambda can reduce all intrahepatic HDV infection markers in HBV/HDV infected humanized mice
Giersch, K., Homs, M., Volz, T., Helbig, M., Allweiss, L., Lohse, A. W., Petersen, J., Buti, M., Pollicino, T., Sureau, C., Dandri, M. & Lütgehetmann, M., 16.06.2017, In: SCI REP-UK. 7, 1, p. 3757Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Animal models of HBV infection
Dandri, M. & Petersen, J., 06.2017, In: BEST PRACT RES CL GA. 31, 3, p. 273-279 7 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Serum HBV pgRNA as a clinical marker for cccDNA activity
Giersch, K., Allweiss, L., Volz, T., Dandri-Petersen, M. & Lütgehetmann, M., 02.2017, In: J HEPATOL. 66, 2, p. 460-462Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunofluorescent Staining for the Detection of the Hepatitis B Core Antigen in Frozen Liver Sections of Human Liver Chimeric Mice
Allweiss, L., Lütgehetmann, M. & Dandri, M., 2017, In: Methods Mol Biol. 1540, p. 135-142 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
A Slow Maturation Process Renders Hepatitis B Virus Infectious
Seitz, S., Iancu, C., Volz, T., Mier, W., Dandri-Petersen, M., Urban, S. & Bartenschlager, R., 13.07.2016, In: CELL HOST MICROBE. 20, 1, p. 25-35Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mechanism of Hepatitis B Virus Persistence in Hepatocytes and Its Carcinogenic Potential
Dandri-Petersen, M. & Petersen, J., 01.06.2016, In: CLIN INFECT DIS. 62 Suppl 4, p. S281-8Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation
Allweiss, L., Gass, S., Giersch, K., Groth, A., Kah, J., Volz, T., Rapp, G., Schöbel, A., Lohse, A. W., Polywka, S., Pischke, S., Herker, E., Dandri-Petersen, M. & Lütgehetmann, M., 01.05.2016, In: J HEPATOL. 64, 5, p. 1033-1040Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer
Bierwolf, J., Volz, T., Lütgehetmann, M., Allweiss, L., Riecken, K., Warlich, M., Fehse, B., Kalff, J. C., Dandri-Petersen, M. & Pollok, J-M., 05.2016, In: TISSUE ENG PT A. 22, 9-10, p. 742-53 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Experimental in vitro and in vivo models for the study of human hepatitis B virus infection
Allweiss, L. & Dandri-Petersen, M., 04.2016, In: J HEPATOL. 64, 1 Suppl, p. S17-31Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Latest developments in the treatment of hepatitis B
Dandri-Petersen, M. & Petersen, J., 03.2016, In: Minerva Gastroenterol Dietol. 62, 1, p. 88-102Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Variability in long-term hepatitis B virus dynamics under antiviral therapy
Murray, J. M., Stancevic, O., Lütgehetmann, M., Wursthorn, K., Petersen, J. & Dandri-Petersen, M., 21.02.2016, In: J THEOR BIOL. 391, p. 74-80 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The challenge of protecting without overprotecting the two sides of myeloid-derived suppressor cells in HBV infection
Dandri-Petersen, M. & Bockmann, J-H., 01.2016, In: HEPATOLOGY. 63, 3, p. 1044-6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review