Research ExplorerScientific StaffManuel Friese Publications

Prof.Dr.med. ID: 40246

Manuel Friese

Head of Clinic

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ORCID: 0000-0001-6380-2420
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Publications

  1. 2015

  2. Neurosarkoidose

    Ufer, F. & Friese, M., 2015, In: AKTUEL NEUROL. 42, 04, p. 218-227

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. 2014

  4. Acquired channelopathies as contributors to development and progression of multiple sclerosis

    Schattling, B., Eggert, B. & Friese, M. A., 01.12.2014, In: EXP NEUROL. 262 Pt A, p. 28-36 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke

    Gelderblom, M., Melzer, N., Schattling, B., Göb, E., Hicking, G., Arunachalam, P., Bittner, S., Ufer, F., Herrmann, A. M., Bernreuther, C., Glatzel, M., Gerloff, C., Kleinschnitz, C., Meuth, S. G., Friese, M. A. & Magnus, T., 01.11.2014, In: STROKE. 45, 11, p. 3395-3402 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. CD8⁺ MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis

    Willing, A., Leach, O. A., Ufer, F., Attfield, K. E., Steinbach, K., Kursawe, N., Piedavent, M. & Friese, M. A., 01.10.2014, In: EUR J IMMUNOL. 44, 10, p. 3119-28 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. A vaccine targeting mutant IDH1 induces antitumour immunity

    Schumacher, T., Bunse, L., Pusch, S., Sahm, F., Wiestler, B., Quandt, J., Menn, O., Osswald, M., Oezen, I., Ott, M., Keil, M., Balß, J., Rauschenbach, K., Grabowska, A. K., Vogler, I., Diekmann, J., Trautwein, N., Eichmüller, S. B., Okun, J., Stevanović, S., Riemer, A. B., Sahin, U., Friese, M. A., Beckhove, P., von Deimling, A., Wick, W. & Platten, M., 21.08.2014, In: NATURE. 512, 7514, p. 324-7 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis

    Friese, M. A., Schattling, B. & Fugger, L., 2014, In: NAT REV NEUROL. 10, 4, p. 225-38 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. 2013

  10. Neutrophils amplify autoimmune central nervous system infiltrates by maturing local APCs

    Steinbach, K., Piedavent, M., Bauer, S., Neumann, J. T. & Friese, M. A., 01.11.2013, In: J IMMUNOL. 191, 9, p. 4531-9 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis

    Gelderblom, M., Daehn, T., Schattling, B., Ludewig, P., Bernreuther, C., Arunachalam, P., Matschke, J., Glatzel, M., Gerloff, C., Friese, M. A. & Magnus, T., 01.11.2013, In: NEUROBIOL DIS. 59, p. 177-82 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Pregnancy and multiple sclerosis: feto-maternal immune cross talk and its implications for disease activity

    Patas, K., Engler, J. B., Friese, M. A. & Gold, S. M., 01.03.2013, In: J REPROD IMMUNOL. 97, 1, p. 140-6 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. A clinical and neurobiological case of IgM NMDA receptor antibody associated encephalitis mimicking bipolar disorder.

    Choe, C-U., Karamatskos, E., Schattling, B., Leypoldt, F., Liuzzi, G., Gerloff, C., Friese, M. A. & Mulert, C., 2013, In: PSYCHIAT RES. 208, 2, p. 194-196 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Enzephalopathien bei Infektionserkrankungen

    Friese, M., Gerloff, C. & Weber, T., 2013, Bewusstseinsstörungen und Enzephalopathien: Diagnose, Therapie, Prognose. Hansen, H-C. (ed.). 1 ed. Berlin, Heidelberg: Springer, p. 327-339 12 p. 21

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review

  15. 2012

  16. CD8-mediated inflammatory central nervous system disorders.

    Willing, A. & Friese, M. A., 2012, In: CURR OPIN NEUROL. 25, 3, p. 316-321 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Critical role of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of inflammation-driven dermal fibrosis in a mouse model of systemic sclerosis.

    Avouac, J., Elhai, M., Tomcik, M., Ruiz, B., Friese, M. A., Piedavent, M., Colonna, M., Bernhardt, G., Kahan, A., Chiocchia, G., Distler, J. H. W. & Allanore, Y., 2012, In: ANN RHEUM DIS. 72(6), p. 1089-1098

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.

    Gelderblom, M., Weymar, A., Bernreuther, C., Velden, J., Arunachalam, P., Steinbach, K., Orthey, E., Arumugam, T. V., Leypoldt, F., Simova, O., Thom, V., Friese, M. A., Prinz, I., Hölscher, C., Glatzel, M., Korn, T., Gerloff, C., Tolosa, E. & Magnus, T., 2012, In: BLOOD. 120, 18, p. 3793-3802 18.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis.

    Schattling, B., Steinbach, K., Thies, E., Kruse, M., Menigoz, A., Ufer, F., Flockerzi, V., Brück, W., Pongs, O., Vennekens, R., Kneussel, M., Freichel, M., Merkler, D. & Friese, M. A., 2012, In: NAT MED. 18, 12, p. 1805-1811 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. 2011

  21. Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model.

    Vergo, S., Craner, M. J., Etzensperger, R., Attfield, K., Friese, M. A., Newcombe, J., Esiri, M. & Fugger, L., 2011, In: BRAIN. 134, 2, p. 571-584 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. [Autoimmune synaptic encephalopathies].

    Friese, M. A. & Magnus, T., 2011, In: NERVENARZT. 82, 10, p. 1239-1249 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. IL-21 and IL-21 receptor expression in lymphocytes and neurons in multiple sclerosis brain.

    Tzartos, J. S., Craner, M. J., Friese, M. A., Jakobsen, K. B., Newcombe, J., Esiri, M. M. & Fugger, L., 2011, In: AM J PATHOL. 178, 2, p. 794-802 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Multiple enlarged nerves on neurosonography: an unusual paraneoplastic case.

    Leypoldt, F., Friese, M. A., Böhm, J. & Bäumer, T., 2011, In: MUSCLE NERVE. 43, 5, p. 756-758 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis.

    McMahon, R. M., Friis, L., Siebold, C., Friese, M. A., Fugger, L. & Jones, E. Y., 2011, In: ACTA CRYSTALLOGR D. 67, Pt 5, p. 447-454 Pt 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. 2010

  27. [Multiple sclerosis].

    Friese, M. A., 2010, In: DEUT MED WOCHENSCHR. 135, 11, p. 527-531 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. N-methyl-D-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes.

    Irani, S. R., Bera, K., Waters, P., Zuliani, L., Maxwell, S., Zandi Michael, S., Friese, M. A., Galea, I., Kullmann, D. M., Beeson, D., Lang, B., Bien, C. G. & Vincent, A., 2010, In: BRAIN. 133, 6, p. 1655-1667 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. 2009

  30. From genes to function: the next challenge to understanding multiple sclerosis.

    Fugger, L., Friese, M. A. & Bell, J. I., 2009, In: NAT REV IMMUNOL.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Pathogenic CD8(+) T cells in multiple sclerosis.

    Friese, M. A. & Fugger, L., 2009, In: ANN NEUROL. 66, 2, p. 132-141 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides.

    Harkiolaki, M., Holmes, S. L., Svendsen, P., Gregersen, J. W., Jensen, L. T., McMahon, R., Friese, M. A., van Boxel, G., Etzensperger, R., Tzartos, J. S., Kranc, K., Sainsbury, S., Harlos, K., Mellins, E. D., Palace, J., Esiri, M. M., Merwe, V. D., Anton, P., Jones, E. Y. & Fugger, L., 2009, In: IMMUNITY. 30, 3, p. 348-357 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. 2008

  34. Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis.

    Tzartos, J. S., Friese, M. A., Craner, M. J., Palace, J., Newcombe, J., Esiri, M. M. & Fugger, L., 2008, In: AM J PATHOL. 172, 1, p. 146-155 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis.

    Friese, M. A., Jakobsen, K. B., Friis, L., Etzensperger, R., Craner, M. J., McMahon, R. M., Jensen, L. T., Huygelen, V., Jones, E. Y., Bell, J. I. & Fugger, L., 2008, In: NAT MED. 14, 11, p. 1227-1235 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. 2007

  37. Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system.

    Friese, M. A., Craner, M. J., Etzensperger, R., Vergo, S., Wemmie, J. A., Welsh, M. J., Vincent, A. & Fugger, L., 2007, In: NAT MED. 13, 12, p. 1483-1489 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. T cells and microglia as drivers of multiple sclerosis pathology.

    Friese, M. A. & Fugger, L., 2007, In: BRAIN. 130, 11, p. 2755-2757 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. 2006

  40. Humanized mouse models for organ-specific autoimmune diseases.

    Friese, M. A., Jensen, L. T., Willcox, N. & Fugger, L., 2006, In: CURR OPIN IMMUNOL. 18, 6, p. 704-709 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Immune stimulatory effects of CD70 override CD70-mediated immune cell apoptosis in rodent glioma models and confer long-lasting antiglioma immunity in vivo.

    Aulwurm, S., Wischhusen, J., Friese, M. A., Borst, J. & Weller, M., 2006, In: INT J CANCER. 118, 7, p. 1728-1735 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. TGF-beta and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells.

    Eisele, G., Wischhusen, J., Mittelbronn, M., Meyermann, R., Waldhauer, I., Steinle, A., Weller, M. & Friese, M. A., 2006, In: BRAIN. 129, 9, p. 2416-2425 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. The value of animal models for drug development in multiple sclerosis.

    Friese, M. A., Montalban, X., Willcox, N., Bell, J. I., Martin, R. & Fugger, L., 2006, In: BRAIN. 129, 8, p. 1940-1952 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. 2005

  45. Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

    Friese, M. A. & Fugger, L., 2005, In: BRAIN. 128, 8, p. 1747-1763 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. HLA-E protects glioma cells from NKG2D-mediated immune responses in vitro: implications for immune escape in vivo.

    Wischhusen, J., Friese, M. A., Mittelbronn, M., Meyermann, R. & Weller, M., 2005, In: J NEUROPATH EXP NEUR. 64, 6, p. 523-528 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. MHC II molecules in inflammatory diseases: interplay of qualities and quantities.

    Friese, M. A., Jones, E. Y. & Fugger, L., 2005, In: TRENDS IMMUNOL. 26, 11, p. 559-561 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Multiple sclerosis: MHC associations and therapeutic implications.

    Holmes, S., Friese, M. A., Siebold, C., Jones, E. Y., Bell, J. & Fugger, L., 2005, In: EXPERT REV MOL MED. 7, 3, p. 1-17 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. 2004

  50. RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo.

    Friese, M. A., Wischhusen, J., Wick, W., Weiler, M., Eisele, G., Steinle, A. & Weller, M., 2004, In: CANCER RES. 64, 20, p. 7596-7603 20.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. The innate immune response in the central nervous system and its role in glioma immune surveillance.

    Friese, M. A., Steinle, A. & Weller, M., 2004, In: ONKOLOGIE. 27, 5, p. 487-491 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. 2003

  53. [Meningoencephalitis caused by Listeria monocytogenes]

    Mehnert, F., Friese, M. A. & Nägele, T., 2003, In: ROFO-FORTSCHR RONTG. 175, 8, p. 1142-1143 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  54. MICA/NKG2D-mediated immunogene therapy of experimental gliomas.

    Friese, M. A., Platten, M., Lutz, S. Z., Naumann, U., Aulwurm, S., Bischof, F., Bühring, H-J., Dichgans, J., Rammensee, H-G., Steinle, A. & Weller, M., 2003, In: CANCER RES. 63, 24, p. 8996-9006 24.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  55. Release of endogenous anti-inflammatory complement regulators FHL-1 and factor H protects synovial fibroblasts during rheumatoid arthritis.

    Friese, M. A., Manuelian, T., Junnikkala, S., Hellwage, J., Meri, S., Peter, H. H., Gordon, D. L., Eibel, H. & Zipfel, P. F., 2003, In: CLIN EXP IMMUNOL. 132, 3, p. 485-495 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  56. 2002

  57. Complement C3b/C3d and cell surface polyanions are recognized by overlapping binding sites on the most carboxyl-terminal domain of complement factor H.

    Hellwage, J., Jokiranta, T. S., Friese, M. A., Wolk, T. U., Kampen, E., Zipfel, P. F. & Meri, S., 2002, In: J IMMUNOL. 169, 12, p. 6935-6944 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  58. 2000

  59. Different regulation of factor H and FHL-1/reconectin by inflammatory mediators and expression of the two proteins in rheumatoid arthritis (RA).

    Friese, M. A., Hellwage, J., Jokiranta, T. S., Meri, S., Müller-Quernheim, H. J., Peter, H. H., Eibel, H. & Zipfel, P. F., 2000, In: CLIN EXP IMMUNOL. 121, 2, p. 406-415 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  60. Exceptional resistance of human H2 glioblastoma cells to complement-mediated killing by expression and utilization of factor H and factor H-like protein 1.

    Junnikkala, S., Jokiranta, T. S., Friese, M. A., Jarva, H., Zipfel, P. F. & Meri, S., 2000, In: J IMMUNOL. 164, 11, p. 6075-6081 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  61. October 1999: 70 year old female with seizures and progressive dementia.

    Friese, M. A., Kern, M. A., Wengler-Becker, U., Rudolf, J. & Schröder, R., 2000, In: BRAIN PATHOL. 10, 1, p. 173-174 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  62. 1999

  63. Factor H and disease: a complement regulator affects vital body functions.

    Zipfel, P. F., Hellwage, J., Friese, M. A., Hegasy, G., Jokiranta, S. T. & Meri, S., 1999, In: MOL IMMUNOL. 36, 4-5, p. 241-248 4-5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  64. FHL-1/reconectin and factor H: two human complement regulators which are encoded by the same gene are differently expressed and regulated.

    Friese, M. A., Hellwage, J., Jokiranta, T. S., Meri, S., Peter, H. H., Eibel, H. & Zipfel, P. F., 1999, In: MOL IMMUNOL. 36, 13-14, p. 809-818 13-14.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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