Prof.Dr.med. ID: 40246
Manuel Friese
Head of Clinic
Publications
- 2015
Neurosarkoidose
Ufer, F. & Friese, M., 2015, In: AKTUEL NEUROL. 42, 04, p. 218-227Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Acquired channelopathies as contributors to development and progression of multiple sclerosis
Schattling, B., Eggert, B. & Friese, M. A., 01.12.2014, In: EXP NEUROL. 262 Pt A, p. 28-36 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke
Gelderblom, M., Melzer, N., Schattling, B., Göb, E., Hicking, G., Arunachalam, P., Bittner, S., Ufer, F., Herrmann, A. M., Bernreuther, C., Glatzel, M., Gerloff, C., Kleinschnitz, C., Meuth, S. G., Friese, M. A. & Magnus, T., 01.11.2014, In: STROKE. 45, 11, p. 3395-3402 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD8⁺ MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis
Willing, A., Leach, O. A., Ufer, F., Attfield, K. E., Steinbach, K., Kursawe, N., Piedavent, M. & Friese, M. A., 01.10.2014, In: EUR J IMMUNOL. 44, 10, p. 3119-28 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A vaccine targeting mutant IDH1 induces antitumour immunity
Schumacher, T., Bunse, L., Pusch, S., Sahm, F., Wiestler, B., Quandt, J., Menn, O., Osswald, M., Oezen, I., Ott, M., Keil, M., Balß, J., Rauschenbach, K., Grabowska, A. K., Vogler, I., Diekmann, J., Trautwein, N., Eichmüller, S. B., Okun, J., Stevanović, S., Riemer, A. B., Sahin, U., Friese, M. A., Beckhove, P., von Deimling, A., Wick, W. & Platten, M., 21.08.2014, In: NATURE. 512, 7514, p. 324-7 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis
Friese, M. A., Schattling, B. & Fugger, L., 2014, In: NAT REV NEUROL. 10, 4, p. 225-38 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Neutrophils amplify autoimmune central nervous system infiltrates by maturing local APCs
Steinbach, K., Piedavent, M., Bauer, S., Neumann, J. T. & Friese, M. A., 01.11.2013, In: J IMMUNOL. 191, 9, p. 4531-9 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis
Gelderblom, M., Daehn, T., Schattling, B., Ludewig, P., Bernreuther, C., Arunachalam, P., Matschke, J., Glatzel, M., Gerloff, C., Friese, M. A. & Magnus, T., 01.11.2013, In: NEUROBIOL DIS. 59, p. 177-82 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pregnancy and multiple sclerosis: feto-maternal immune cross talk and its implications for disease activity
Patas, K., Engler, J. B., Friese, M. A. & Gold, S. M., 01.03.2013, In: J REPROD IMMUNOL. 97, 1, p. 140-6 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A clinical and neurobiological case of IgM NMDA receptor antibody associated encephalitis mimicking bipolar disorder.
Choe, C-U., Karamatskos, E., Schattling, B., Leypoldt, F., Liuzzi, G., Gerloff, C., Friese, M. A. & Mulert, C., 2013, In: PSYCHIAT RES. 208, 2, p. 194-196 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Enzephalopathien bei Infektionserkrankungen
Friese, M., Gerloff, C. & Weber, T., 2013, Bewusstseinsstörungen und Enzephalopathien: Diagnose, Therapie, Prognose. Hansen, H-C. (ed.). 1 ed. Berlin, Heidelberg: Springer, p. 327-339 12 p. 21Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2012
CD8-mediated inflammatory central nervous system disorders.
Willing, A. & Friese, M. A., 2012, In: CURR OPIN NEUROL. 25, 3, p. 316-321 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Critical role of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of inflammation-driven dermal fibrosis in a mouse model of systemic sclerosis.
Avouac, J., Elhai, M., Tomcik, M., Ruiz, B., Friese, M. A., Piedavent, M., Colonna, M., Bernhardt, G., Kahan, A., Chiocchia, G., Distler, J. H. W. & Allanore, Y., 2012, In: ANN RHEUM DIS. 72(6), p. 1089-1098Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Gelderblom, M., Weymar, A., Bernreuther, C., Velden, J., Arunachalam, P., Steinbach, K., Orthey, E., Arumugam, T. V., Leypoldt, F., Simova, O., Thom, V., Friese, M. A., Prinz, I., Hölscher, C., Glatzel, M., Korn, T., Gerloff, C., Tolosa, E. & Magnus, T., 2012, In: BLOOD. 120, 18, p. 3793-3802 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis.
Schattling, B., Steinbach, K., Thies, E., Kruse, M., Menigoz, A., Ufer, F., Flockerzi, V., Brück, W., Pongs, O., Vennekens, R., Kneussel, M., Freichel, M., Merkler, D. & Friese, M. A., 2012, In: NAT MED. 18, 12, p. 1805-1811 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model.
Vergo, S., Craner, M. J., Etzensperger, R., Attfield, K., Friese, M. A., Newcombe, J., Esiri, M. & Fugger, L., 2011, In: BRAIN. 134, 2, p. 571-584 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Autoimmune synaptic encephalopathies].
Friese, M. A. & Magnus, T., 2011, In: NERVENARZT. 82, 10, p. 1239-1249 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-21 and IL-21 receptor expression in lymphocytes and neurons in multiple sclerosis brain.
Tzartos, J. S., Craner, M. J., Friese, M. A., Jakobsen, K. B., Newcombe, J., Esiri, M. M. & Fugger, L., 2011, In: AM J PATHOL. 178, 2, p. 794-802 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiple enlarged nerves on neurosonography: an unusual paraneoplastic case.
Leypoldt, F., Friese, M. A., Böhm, J. & Bäumer, T., 2011, In: MUSCLE NERVE. 43, 5, p. 756-758 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis.
McMahon, R. M., Friis, L., Siebold, C., Friese, M. A., Fugger, L. & Jones, E. Y., 2011, In: ACTA CRYSTALLOGR D. 67, Pt 5, p. 447-454 Pt 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
[Multiple sclerosis].
Friese, M. A., 2010, In: DEUT MED WOCHENSCHR. 135, 11, p. 527-531 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
N-methyl-D-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes.
Irani, S. R., Bera, K., Waters, P., Zuliani, L., Maxwell, S., Zandi Michael, S., Friese, M. A., Galea, I., Kullmann, D. M., Beeson, D., Lang, B., Bien, C. G. & Vincent, A., 2010, In: BRAIN. 133, 6, p. 1655-1667 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
From genes to function: the next challenge to understanding multiple sclerosis.
Fugger, L., Friese, M. A. & Bell, J. I., 2009, In: NAT REV IMMUNOL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pathogenic CD8(+) T cells in multiple sclerosis.
Friese, M. A. & Fugger, L., 2009, In: ANN NEUROL. 66, 2, p. 132-141 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides.
Harkiolaki, M., Holmes, S. L., Svendsen, P., Gregersen, J. W., Jensen, L. T., McMahon, R., Friese, M. A., van Boxel, G., Etzensperger, R., Tzartos, J. S., Kranc, K., Sainsbury, S., Harlos, K., Mellins, E. D., Palace, J., Esiri, M. M., Merwe, V. D., Anton, P., Jones, E. Y. & Fugger, L., 2009, In: IMMUNITY. 30, 3, p. 348-357 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis.
Tzartos, J. S., Friese, M. A., Craner, M. J., Palace, J., Newcombe, J., Esiri, M. M. & Fugger, L., 2008, In: AM J PATHOL. 172, 1, p. 146-155 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis.
Friese, M. A., Jakobsen, K. B., Friis, L., Etzensperger, R., Craner, M. J., McMahon, R. M., Jensen, L. T., Huygelen, V., Jones, E. Y., Bell, J. I. & Fugger, L., 2008, In: NAT MED. 14, 11, p. 1227-1235 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system.
Friese, M. A., Craner, M. J., Etzensperger, R., Vergo, S., Wemmie, J. A., Welsh, M. J., Vincent, A. & Fugger, L., 2007, In: NAT MED. 13, 12, p. 1483-1489 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
T cells and microglia as drivers of multiple sclerosis pathology.
Friese, M. A. & Fugger, L., 2007, In: BRAIN. 130, 11, p. 2755-2757 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2006
Humanized mouse models for organ-specific autoimmune diseases.
Friese, M. A., Jensen, L. T., Willcox, N. & Fugger, L., 2006, In: CURR OPIN IMMUNOL. 18, 6, p. 704-709 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immune stimulatory effects of CD70 override CD70-mediated immune cell apoptosis in rodent glioma models and confer long-lasting antiglioma immunity in vivo.
Aulwurm, S., Wischhusen, J., Friese, M. A., Borst, J. & Weller, M., 2006, In: INT J CANCER. 118, 7, p. 1728-1735 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TGF-beta and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells.
Eisele, G., Wischhusen, J., Mittelbronn, M., Meyermann, R., Waldhauer, I., Steinle, A., Weller, M. & Friese, M. A., 2006, In: BRAIN. 129, 9, p. 2416-2425 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The value of animal models for drug development in multiple sclerosis.
Friese, M. A., Montalban, X., Willcox, N., Bell, J. I., Martin, R. & Fugger, L., 2006, In: BRAIN. 129, 8, p. 1940-1952 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2005
Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?
Friese, M. A. & Fugger, L., 2005, In: BRAIN. 128, 8, p. 1747-1763 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HLA-E protects glioma cells from NKG2D-mediated immune responses in vitro: implications for immune escape in vivo.
Wischhusen, J., Friese, M. A., Mittelbronn, M., Meyermann, R. & Weller, M., 2005, In: J NEUROPATH EXP NEUR. 64, 6, p. 523-528 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MHC II molecules in inflammatory diseases: interplay of qualities and quantities.
Friese, M. A., Jones, E. Y. & Fugger, L., 2005, In: TRENDS IMMUNOL. 26, 11, p. 559-561 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiple sclerosis: MHC associations and therapeutic implications.
Holmes, S., Friese, M. A., Siebold, C., Jones, E. Y., Bell, J. & Fugger, L., 2005, In: EXPERT REV MOL MED. 7, 3, p. 1-17 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2004
RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo.
Friese, M. A., Wischhusen, J., Wick, W., Weiler, M., Eisele, G., Steinle, A. & Weller, M., 2004, In: CANCER RES. 64, 20, p. 7596-7603 20.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The innate immune response in the central nervous system and its role in glioma immune surveillance.
Friese, M. A., Steinle, A. & Weller, M., 2004, In: ONKOLOGIE. 27, 5, p. 487-491 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2003
[Meningoencephalitis caused by Listeria monocytogenes]
Mehnert, F., Friese, M. A. & Nägele, T., 2003, In: ROFO-FORTSCHR RONTG. 175, 8, p. 1142-1143 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MICA/NKG2D-mediated immunogene therapy of experimental gliomas.
Friese, M. A., Platten, M., Lutz, S. Z., Naumann, U., Aulwurm, S., Bischof, F., Bühring, H-J., Dichgans, J., Rammensee, H-G., Steinle, A. & Weller, M., 2003, In: CANCER RES. 63, 24, p. 8996-9006 24.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Release of endogenous anti-inflammatory complement regulators FHL-1 and factor H protects synovial fibroblasts during rheumatoid arthritis.
Friese, M. A., Manuelian, T., Junnikkala, S., Hellwage, J., Meri, S., Peter, H. H., Gordon, D. L., Eibel, H. & Zipfel, P. F., 2003, In: CLIN EXP IMMUNOL. 132, 3, p. 485-495 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2002
Complement C3b/C3d and cell surface polyanions are recognized by overlapping binding sites on the most carboxyl-terminal domain of complement factor H.
Hellwage, J., Jokiranta, T. S., Friese, M. A., Wolk, T. U., Kampen, E., Zipfel, P. F. & Meri, S., 2002, In: J IMMUNOL. 169, 12, p. 6935-6944 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2000
Different regulation of factor H and FHL-1/reconectin by inflammatory mediators and expression of the two proteins in rheumatoid arthritis (RA).
Friese, M. A., Hellwage, J., Jokiranta, T. S., Meri, S., Müller-Quernheim, H. J., Peter, H. H., Eibel, H. & Zipfel, P. F., 2000, In: CLIN EXP IMMUNOL. 121, 2, p. 406-415 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Exceptional resistance of human H2 glioblastoma cells to complement-mediated killing by expression and utilization of factor H and factor H-like protein 1.
Junnikkala, S., Jokiranta, T. S., Friese, M. A., Jarva, H., Zipfel, P. F. & Meri, S., 2000, In: J IMMUNOL. 164, 11, p. 6075-6081 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
October 1999: 70 year old female with seizures and progressive dementia.
Friese, M. A., Kern, M. A., Wengler-Becker, U., Rudolf, J. & Schröder, R., 2000, In: BRAIN PATHOL. 10, 1, p. 173-174 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1999
Factor H and disease: a complement regulator affects vital body functions.
Zipfel, P. F., Hellwage, J., Friese, M. A., Hegasy, G., Jokiranta, S. T. & Meri, S., 1999, In: MOL IMMUNOL. 36, 4-5, p. 241-248 4-5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
FHL-1/reconectin and factor H: two human complement regulators which are encoded by the same gene are differently expressed and regulated.
Friese, M. A., Hellwage, J., Jokiranta, T. S., Meri, S., Peter, H. H., Eibel, H. & Zipfel, P. F., 1999, In: MOL IMMUNOL. 36, 13-14, p. 809-818 13-14.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review