Research ExplorerScientific StaffKatja Giersch Publications

PhD ID: 44852

Katja Giersch

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Affiliations
1 - 24 out of 24Page size: 50

Publications

  1. 2024

  2. Analytical and clinical validation of a multiplex PCR assay for detection of Neisseria gonorrhoeae and Chlamydia trachomatis including simultaneous LGV serotyping on an automated high-throughput PCR system

    Pflüger, L. S., Nörz, D., Grunwald, M., Pfefferle, S., Giersch, K., Christner, M., Weber, B., Aepfelbacher, M., Rohde, H. & Lütgehetmann, M., 05.03.2024, In: MICROBIOL SPECTR. 12, 3, p. e0275623

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Transfer › peer-review

  3. Adaptation and validation of a quantitative vanA/vanB DNA screening assay on a high-throughput PCR system

    Giersch, K., Tanida, K., Both, A., Nörz, D., Heim, D., Rohde, H., Aepfelbacher, M. & Lütgehetmann, M., 12.02.2024, In: SCI REP-UK. 14, 1, p. 3523

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Transfer › peer-review

  4. 2023

  5. Strain-specific responsiveness of hepatitis D virus to interferon-alpha treatment

    Giersch, K., Perez-Gonzalez, P., Hendricks, L., Goldmann, N., Kolbe, J., Hermanussen, L., Bockmann, J-H., Volz, T., Volmari, A., Allweiss, L., Petersen, J., Glebe, D., Lütgehetmann, M. & Dandri, M., 04.2023, In: JHEP REP. 5, 4, p. 100673

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. 2022

  7. Rapid Adaptation of Established High-Throughput Molecular Testing Infrastructure for Monkeypox Virus Detection

    Nörz, D., Tang, H. T., Emmerich, P., Giersch, K., Fischer, N., Schmiedel, S., Addo, M. M., Aepfelbacher, M., Pfefferle, S. & Lütgehetmann, M., 09.2022, In: EMERG INFECT DIS. 28, 9, p. 1765-1769 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage Variants

    Nörz, D., Grunwald, M., Tang, H. T., Weinschenk, C., Günther, T., Robitaille, A., Giersch, K., Fischer, N., Grundhoff, A., Aepfelbacher, M., Pfefferle, S. & Lütgehetmann, M., 15.03.2022, In: VIRUSES-BASEL. 14, 3, 608.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo

    Allweiss, L., Giersch, K., Pirosu, A., Volz, T., Muench, R. C., Beran, R. K., Urban, S., Javanbakht, H., Fletcher, S. P., Lütgehetmann, M. & Dandri-Petersen, M., 02.2022, In: GUT. 71, 2, p. 372-381 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. 2021

  11. Clinical establishment of a laboratory developed quantitative HDV PCR assay on the cobas6800 high-throughput system

    Pflüger, L. S., Nörz, D., Volz, T., Giersch, K., Giese, A., Goldmann, N., Glebe, D., Bockmann, J-H., Pfefferle, S., Dandri, M., Schulze Zur Wiesch, J. & Lütgehetmann, M., 12.2021, In: JHEP REP. 3, 6, 100356.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. In Vivo Models of HDV Infection: Is Humanizing NTCP Enough?

    Giersch, K. & Dandri, M., 31.03.2021, In: VIRUSES-BASEL. 13, 4, p. 588

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  13. Murine hepatocytes do not support persistence of Hepatitis D Virus mono-infection in vivo

    Giersch, K., Hermanussen, L., Volz, T., Kah, J., Allweiss, L., Casey, J., Sureau, C., Dandri, M. & Lütgehetmann, M., 02.2021, In: LIVER INT. 41, 2, p. 410-419 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Strong Replication Interference Between Hepatitis Delta Viruses in Human Liver Chimeric Mice

    Giersch, K., Hermanussen, L., Volz, T., Volmari, A., Allweiss, L., Sureau, C., Casey, J., Huang, J., Fischer, N., Lütgehetmann, M. & Dandri, M., 2021, In: FRONT MICROBIOL. 12, p. 671466

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. 2020

  16. Hepatitis Delta Virus Acts as an Immunogenic Adjuvant in Hepatitis B Virus-Infected Hepatocytes

    Tham, C. Y. L., Kah, J., Tan, A. T., Volz, T., Chia, A., Giersch, K., Ladiges, Y., Loglio, A., Borghi, M., Sureau, C., Lampertico, P., Lütgehetmann, M., Dandri-Petersen, M. & Bertoletti, A., 21.07.2020, In: CELL REP MED. 1, 4, p. 100060

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. High rates of cirrhosis and severe clinical events in patients with HBV/HDV co-infection:longitudinal analysis of a German cohort:longitudinal analysis of a German cohort

    Bockmann, J-H., Grube, M., Hamed, V., von Felden, J., Landahl, J., Wehmeyer, M., Giersch, K., Hall, M. T., Murray, J. M., Dandri, M., Lüth, S., Lohse, A. W., Lütgehetmann, M. & Schulze Zur Wiesch, J., 30.01.2020, In: BMC GASTROENTEROL. 20, 1, p. 24

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. 2019

  19. Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo

    Giersch, K., Bhadra, O. D., Volz, T., Allweiss, L., Riecken, K., Fehse, B., Lohse, A. W., Petersen, J., Sureau, C., Urban, S., Dandri, M. & Lütgehetmann, M., 01.2019, In: GUT. 68, 1, p. 150-157 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. 2018

  21. Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection

    Winer, B. Y., Shirvani-Dastgerdi, E., Bram, Y., Sellau, J., Low, B. E., Johnson, H., Huang, T., Hrebikova, G., Heller, B., Sharon, Y., Giersch, K., Gerges, S., Seneca, K., Pais, M-A., Frankel, A. S., Chiriboga, L., Cullen, J., Nahass, R. G., Lutgehetmann, M., Toettcher, J. E., Wiles, M. V., Schwartz, R. E. & Ploss, A., 27.06.2018, In: SCI TRANSL MED. 10, 447, p. eaap9328

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo

    Allweiss, L., Volz, T., Giersch, K., Kah, J., Raffa, G., Petersen, J., Lohse, A. W., Beninati, C., Pollicino, T., Urban, S., Lütgehetmann, M. & Dandri, M., 03.2018, In: GUT. 67, 3, p. 542-552 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. 2017

  24. Both interferon alpha and lambda can reduce all intrahepatic HDV infection markers in HBV/HDV infected humanized mice

    Giersch, K., Homs, M., Volz, T., Helbig, M., Allweiss, L., Lohse, A. W., Petersen, J., Buti, M., Pollicino, T., Sureau, C., Dandri, M. & Lütgehetmann, M., 16.06.2017, In: SCI REP-UK. 7, 1, p. 3757

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Serum HBV pgRNA as a clinical marker for cccDNA activity

    Giersch, K., Allweiss, L., Volz, T., Dandri-Petersen, M. & Lütgehetmann, M., 02.2017, In: J HEPATOL. 66, 2, p. 460-462

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. 2016

  27. Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation

    Allweiss, L., Gass, S., Giersch, K., Groth, A., Kah, J., Volz, T., Rapp, G., Schöbel, A., Lohse, A. W., Polywka, S., Pischke, S., Herker, E., Dandri-Petersen, M. & Lütgehetmann, M., 01.05.2016, In: J HEPATOL. 64, 5, p. 1033-1040

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. 2015

  29. Hepatitis B and Delta Virus: Advances on Studies about Interactions between the Two Viruses and the Infected Hepatocyte

    Giersch, K. & Dandri-Petersen, M., 28.09.2015, In: J CLIN TRANSL HEPATO. 3, 3, p. 220-229

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection

    Giersch, K., Allweiss, L., Volz, T., Helbig, M., Bierwolf, J., Lohse, A. W., Pollok, J. M., Petersen, J., Dandri-Petersen, M. & Lütgehetmann, M., 08.2015, In: J HEPATOL. 63, 2, p. 346-53 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. 2014

  32. Relevance of a Full-Length Genomic RNA Standard and a Thermal-Shock Step for Optimal Hepatitis Delta Virus Quantification

    Homs, M., Giersch, K., Blasi, M., Lütgehetmann, M., Buti, M., Esteban, R., Dandri, M. & Rodriguez-Frias, F., 01.09.2014, In: J CLIN MICROBIOL. 52, 9, p. 3334-8 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism

    Oehler, N., Volz, T., Bhadra, O. D., Kah, J., Allweiss, L., Giersch, K., Bierwolf, J., Riecken, K., Pollok, J. M., Lohse, A. W., Fehse, B., Petersen, J., Urban, S., Lütgehetmann, M., Heeren, J. & Dandri, M., 08.04.2014, In: HEPATOLOGY.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration

    Allweiss, L., Volz, T., Lütgehetmann, M., Giersch, K., Bornscheuer, T., Lohse, A. W., Petersen, J., Ma, H., Klumpp, K., Fletcher, S. P. & Dandri, M., 01.03.2014, In: J HEPATOL. 60, 3, p. 500-7 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection

    Giersch, K., Helbig, M., Volz, T., Allweiss, L., Mancke, L., Lohse, A. W., Polywka, S., Pollok, J. M., Petersen, J., Taylor, J., Dandri, M. & Lütgehetmann, M., 01.03.2014, In: J HEPATOL. 60, 3, p. 538-44 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review