Joseph Tintelnot

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Publications

  1. 2024
  2. Efficacy and quality of life for FOLFOX/bevacizumab +/- irinotecan in first-line metastatic colorectal cancer-final results of the AIO CHARTA trial

    Schmoll, H-J., Mann, J., Meinert, F., Garlipp, B., Borchert, K., Vogel, A., Goekkurt, E., Kaiser, U., Hoeffkes, H-G., Rüssel, J., Kanzler, S., Edelmann, T., Forstbauer, H., Göhler, T., Hannig, C., Hildebrandt, B., Roll, C., Bokemeyer, C., Steighardt, J., Cygon, F., Ibach, S., Stein, A. & Tintelnot, J., 02.2024, In: BRIT J CANCER. 130, 2, p. 233-241 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Diet and immune response: how today's plate shapes tomorrow's health

    Siracusa, F., Tintelnot, J., Cortesi, F. & Gagliani, N., 01.2024, In: TRENDS IMMUNOL. 45, 1, p. 4-10 7 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  4. 2023
  5. Calcium channel β3 subunit regulates ATP-dependent migration of dendritic cells

    Woo, M. S., Ufer, F., Sonner, J. K., Belkacemi, A., Tintelnot, J., Sáez, P. J., Krieg, P. F., Mayer, C., Binkle-Ladisch, L., Engler, J. B., Bauer, S., Kursawe, N., Vieira, V., Mannebach, S., Freichel, M., Flockerzi, V., Vargas, P. & Friese, M. A., 22.09.2023, In: SCI ADV. 9, 38, eadh1653.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. First-line treatment of unresectable or metastatic HER2 positive esophagogastric adenocarcinoma: liquid biomarker analysis of the phase 2 INTEGA trial

    Paschold, L., Stein, A., Thiele, B., Tintelnot, J., Henkes, S-S., Coith, C., Schultheiß, C., Pantel, K., Riethdorf, S. & Binder, M., 06.2023, In: J IMMUNOTHER CANCER. 11, 6, e006678.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Peripheral and Portal Venous KRAS ctDNA Detection as Independent Prognostic Markers of Early Tumor Recurrence in Pancreatic Ductal Adenocarcinoma

    Nitschke, C., Markmann, B., Walter, P., Badbaran, A., Tölle, M., Kropidlowski, J., Belloum, Y., Goetz, M. R., Bardenhagen, J., Stern, L., Tintelnot, J., Schönlein, M., Sinn, M., van der Leest, P., Simon, R., Heumann, A., Izbicki, J. R., Pantel, K., Wikman, H. & Uzunoglu, F. G., 01.03.2023, In: CLIN CHEM. 69, 3, p. 295-307 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer

    Tintelnot, J., Xu, Y., Lesker, T. R., Schönlein, M., Konczalla, L., Giannou, A. D., Pelczar, P., Kylies, D., Puelles, V. G., Bielecka, A. A., Peschka, M., Cortesi, F., Riecken, K., Jung, M., Amend, L., Bröring, T. S., Trajkovic-Arsic, M., Siveke, J. T., Renné, T., Zhang, D., Boeck, S., Strowig, T., Uzunoglu, F. G., Güngör, C., Stein, A., Izbicki, J. R., Bokemeyer, C., Sinn, M., Kimmelman, A. C., Huber, S. & Gagliani, N., 03.2023, In: NATURE. 615, 7950, p. 168-174 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis

    Zhang, T., Wahib, R., Zazara, D. E., Lücke, J., Shiri, A. M., Kempski, J., Zhao, L., Agalioti, T., Machicote, A. P., Giannou, O., Belios, I., Jia, R., Zhang, S., Tintelnot, J., Seese, H., Grass, J. K., Mercanoglu, B., Stern, L., Scognamiglio, P., Fard-Aghaie, M., Seeger, P., Wakker, J., Kemper, M., Brunswig, B., Duprée, A., Lykoudis, P. M., Pikouli, A., Giorgakis, E., Stringa, P., Lausada, N., Gentilini, M. V., Gondolesi, G. E., Bachmann, K., Busch, P., Grotelüschen, R., Maroulis, I. C., Arck, P. C., Nakano, R., Thomson, A. W., Ghadban, T., Tachezy, M., Melling, N., Achilles, E-G., Puelles, V. G., Nickel, F., Hackert, T., Mann, O., Izbicki, J. R., Li, J., Gagliani, N., Huber, S. & Giannou, A. D., 2023, In: ONCOIMMUNOLOGY. 12, 1, p. 2269634

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Combining Poly-(ARD-Ribose) Polymerase and Programmed Cell Death Protein 1 Inhibition in a Patient with Esophagogastric Adenocarcinoma

    Artzenroth, J. C., Tintelnot, J., Haag, G. M., Gökkurt, E., Steffens, J. & Stein, A., 2023, In: ONCOL RES TREAT. 46, 7-8, p. 320-325 6 p.

    Research output: SCORING: Contribution to journalCase reportResearchpeer-review

  11. IL-22BP controls the progression of liver metastasis in colorectal cancer

    Giannou, A. D., Kempski, J., Zhang, T., Lücke, J., Shiri, A. M., Zazara, D. E., Belios, I., Machicote, A., Seeger, P., Agalioti, T., Tintelnot, J., Sagebiel, A., Tomczak, M., Bauditz, L., Bedke, T., Kocheise, L., Mercanoglu, B., Fard-Aghaie, M., Giorgakis, E., Lykoudis, P. M., Pikouli, A., Grass, J-K., Wahib, R., Bardenhagen, J., Brunswig, B., Heumann, A., Ghadban, T., Duprée, A., Tachezy, M., Melling, N., Arck, P. C., Stringa, P., Gentilini, M. V., Gondolesi, G. E., Nakano, R., Thomson, A. W., Perez, D., Li, J., Mann, O., Izbicki, J. R., Gagliani, N., Maroulis, I. C. & Huber, S., 2023, In: FRONT ONCOL. 13, p. 1170502

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Pembrolizumab and trastuzumab in combination with FLOT in the perioperative treatment of HER2-positive, localized esophagogastric adenocarcinoma-a phase II trial of the AIO study group (AIO STO 0321)

    Tintelnot, J., Stein, A., Al-Batran, S-E., Ettrich, T., Götze, T., Grün, B., Haag, G. M., Heuer, V., Hofheinz, R-D., Homann, N., Bröring, T. S., Cruz, M. S., Kurreck, A., Lorenzen, S., Moosmann, N., Müller, C., Schuler, M., Siegler, G., Binder, M. & Gökkurt, E., 2023, In: FRONT ONCOL. 13, p. 1272175

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. 2022
  14. Efficacy of Ipilimumab vs FOLFOX in Combination With Nivolumab and Trastuzumab in Patients With Previously Untreated ERBB2-Positive Esophagogastric Adenocarcinoma: The AIO INTEGA Randomized Clinical Trial

    Stein, A., Paschold, L., Tintelnot, J., Goekkurt, E., Henkes, S-S., Simnica, D., Schultheiss, C., Willscher, E., Bauer, M., Wickenhauser, C., Thuss-Patience, P., Lorenzen, S., Ettrich, T., Riera-Knorrenschild, J., Jacobasch, L., Kretzschmar, A., Kubicka, S., Al-Batran, S-E., Reinacher-Schick, A., Pink, D., Sinn, M., Lindig, U., Hiegl, W., Hinke, A., Hegewisch-Becker, S. & Binder, M., 01.08.2022, In: JAMA ONCOL. 8, 8, p. 1150-1158 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Translational analysis and final efficacy of the AVETUX trial - Avelumab, cetuximab and FOLFOX in metastatic colorectal cancer

    Tintelnot, J., Ristow, I., Sauer, M., Simnica, D., Schultheiß, C., Scholz, R., Goekkurt, E., von Wenserski, L., Willscher, E., Paschold, L., Lorenzen, S., Riera-Knorrenschild, J., Depenbusch, R., Ettrich, T. J., Dörfel, S., Al-Batran, S-E., Karthaus, M., Pelzer, U., Hinke, A., Bauer, M., Massa, C., Seliger, B., Wickenhauser, C., Bokemeyer, C., Hegewisch-Becker, S., Binder, M. & Stein, A., 2022, In: FRONT ONCOL. 12, 993611.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. 2021
  17. A Phase I dose-escalation study of third-line regorafenib with trifluridine/tipiracil in metastatic colorectal cancer

    Moehler, M., Michel, M., Stein, A., Trojan, J., Marquardt, J., Tintelnot, J., Waidmann, O., Weinmann, A., Woerns, M-A., Schroeder, H., Maenz, M. & Foerster, F., 09.2021, In: FUTURE ONCOL. 17, 25, p. 3309-3319 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer

    Stein, A., Simnica, D., Schultheiß, C., Scholz, R., Tintelnot, J., Gökkurt, E., von Wenserski, L., Willscher, E., Paschold, L., Sauer, M., Lorenzen, S., Riera-Knorrenschild, J., Depenbusch, R., Ettrich, T. J., Dörfel, S., Al-Batran, S-E., Karthaus, M., Pelzer, U., Waberer, L., Hinke, A., Bauer, M., Massa, C., Seliger, B., Wickenhauser, C., Bokemeyer, C., Hegewisch-Becker, S. & Binder, M., 07.2021, In: J IMMUNOTHER CANCER. 9, 7, e002844.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. 2020
  20. Ipilimumab or FOLFOX with Nivolumab and Trastuzumab in previously untreated HER2-positive locally advanced or metastatic EsophagoGastric Adenocarcinoma - the randomized phase 2 INTEGA trial (AIO STO 0217)

    Tintelnot, J., Goekkurt, E., Binder, M., Thuss-Patience, P., Lorenzen, S., Knorrenschild, J. R., Kretzschmar, A., Ettrich, T., Lindig, U., Jacobasch, L., Pink, D., Al-Batran, S-E., Hinke, A., Hegewisch-Becker, S., Nilsson, S., Bokemeyer, C. & Stein, A., 01.06.2020, In: BMC CANCER. 20, 1, p. 503

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. 2019
  22. Immunotherapy in colorectal cancer: Available clinical evidence, challenges and novel approaches

    Tintelnot, J. & Stein, A., 07.08.2019, In: WORLD J GASTROENTERO. 25, 29, p. 3920-3928 9 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  23. Arc/Arg3.1 defines dendritic cells and Langerhans cells with superior migratory ability independent of phenotype and ontogeny in mice

    Tintelnot, J., Ufer, F., Engler, J. B., Winkler, H., Lücke, K., Mittrücker, H-W. & Friese, M. A., 05.2019, In: EUR J IMMUNOL. 49, 5, p. 724-736 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Nanobody-targeting of epidermal growth factor receptor (EGFR) ectodomain variants overcomes resistance to therapeutic EGFR antibodies

    Tintelnot, J., Baum, N., Schultheiss, C., Braig, F., Trentmann, M., Finter, J., Fumey, W., Bannas, P., Fehse, B., Riecken, K., Schütze, K., Bokemeyer, C., Rösner, T., Valerius, T., Peipp, M., Koch-Nolte, F. & Binder, M., 04.2019, In: MOL CANCER THER. 18, 4, p. 823-833 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Cancer Cells Expressing Oncogenic Rat Sarcoma Show Drug-Addiction Toward Epidermal Growth Factor Receptor Antibodies Mediated by Sustained MAPK Signaling

    Tintelnot, J., Metz, S., Trentmann, M., Oberle, A., von Wenserski, L., Schultheiß, C., Braig, F., Kriegs, M., Fehse, B., Riecken, K., Bokemeyer, C., Stein, A. & Binder, M., 2019, In: FRONT ONCOL. 9, p. 1559

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. 2016
  27. Arc/Arg3.1 governs inflammatory dendritic cell migration from the skin and thereby controls T cell activation

    Ufer, F., Vargas, P., Engler, J. B., Tintelnot, J., Schattling, B., Winkler, H., Bauer, S., Kursawe, N., Willing, A., Keminer, O., Ohana, O., Salinas-Riester, G., Pless, O., Kuhl, D. & Friese, M. A., 23.09.2016, In: SCI IMMUNOL. 1, 3, p. eaaf8665

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review