Joseph Tintelnot
Publications
- 2024
Efficacy and quality of life for FOLFOX/bevacizumab +/- irinotecan in first-line metastatic colorectal cancer-final results of the AIO CHARTA trial
Schmoll, H-J., Mann, J., Meinert, F., Garlipp, B., Borchert, K., Vogel, A., Goekkurt, E., Kaiser, U., Hoeffkes, H-G., Rüssel, J., Kanzler, S., Edelmann, T., Forstbauer, H., Göhler, T., Hannig, C., Hildebrandt, B., Roll, C., Bokemeyer, C., Steighardt, J., Cygon, F., Ibach, S., Stein, A. & Tintelnot, J., 02.2024, In: BRIT J CANCER. 130, 2, p. 233-241 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diet and immune response: how today's plate shapes tomorrow's health
Siracusa, F., Tintelnot, J., Cortesi, F. & Gagliani, N., 01.2024, In: TRENDS IMMUNOL. 45, 1, p. 4-10 7 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2023
Calcium channel β3 subunit regulates ATP-dependent migration of dendritic cells
Woo, M. S., Ufer, F., Sonner, J. K., Belkacemi, A., Tintelnot, J., Sáez, P. J., Krieg, P. F., Mayer, C., Binkle-Ladisch, L., Engler, J. B., Bauer, S., Kursawe, N., Vieira, V., Mannebach, S., Freichel, M., Flockerzi, V., Vargas, P. & Friese, M. A., 22.09.2023, In: SCI ADV. 9, 38, eadh1653.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
First-line treatment of unresectable or metastatic HER2 positive esophagogastric adenocarcinoma: liquid biomarker analysis of the phase 2 INTEGA trial
Paschold, L., Stein, A., Thiele, B., Tintelnot, J., Henkes, S-S., Coith, C., Schultheiß, C., Pantel, K., Riethdorf, S. & Binder, M., 06.2023, In: J IMMUNOTHER CANCER. 11, 6, e006678.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Peripheral and Portal Venous KRAS ctDNA Detection as Independent Prognostic Markers of Early Tumor Recurrence in Pancreatic Ductal Adenocarcinoma
Nitschke, C., Markmann, B., Walter, P., Badbaran, A., Tölle, M., Kropidlowski, J., Belloum, Y., Goetz, M. R., Bardenhagen, J., Stern, L., Tintelnot, J., Schönlein, M., Sinn, M., van der Leest, P., Simon, R., Heumann, A., Izbicki, J. R., Pantel, K., Wikman, H. & Uzunoglu, F. G., 01.03.2023, In: CLIN CHEM. 69, 3, p. 295-307 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
Tintelnot, J., Xu, Y., Lesker, T. R., Schönlein, M., Konczalla, L., Giannou, A. D., Pelczar, P., Kylies, D., Puelles, V. G., Bielecka, A. A., Peschka, M., Cortesi, F., Riecken, K., Jung, M., Amend, L., Bröring, T. S., Trajkovic-Arsic, M., Siveke, J. T., Renné, T., Zhang, D., Boeck, S., Strowig, T., Uzunoglu, F. G., Güngör, C., Stein, A., Izbicki, J. R., Bokemeyer, C., Sinn, M., Kimmelman, A. C., Huber, S. & Gagliani, N., 03.2023, In: NATURE. 615, 7950, p. 168-174 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis
Zhang, T., Wahib, R., Zazara, D. E., Lücke, J., Shiri, A. M., Kempski, J., Zhao, L., Agalioti, T., Machicote, A. P., Giannou, O., Belios, I., Jia, R., Zhang, S., Tintelnot, J., Seese, H., Grass, J. K., Mercanoglu, B., Stern, L., Scognamiglio, P., Fard-Aghaie, M., Seeger, P., Wakker, J., Kemper, M., Brunswig, B., Duprée, A., Lykoudis, P. M., Pikouli, A., Giorgakis, E., Stringa, P., Lausada, N., Gentilini, M. V., Gondolesi, G. E., Bachmann, K., Busch, P., Grotelüschen, R., Maroulis, I. C., Arck, P. C., Nakano, R., Thomson, A. W., Ghadban, T., Tachezy, M., Melling, N., Achilles, E-G., Puelles, V. G., Nickel, F., Hackert, T., Mann, O., Izbicki, J. R., Li, J., Gagliani, N., Huber, S. & Giannou, A. D., 2023, In: ONCOIMMUNOLOGY. 12, 1, p. 2269634Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Combining Poly-(ARD-Ribose) Polymerase and Programmed Cell Death Protein 1 Inhibition in a Patient with Esophagogastric Adenocarcinoma
Artzenroth, J. C., Tintelnot, J., Haag, G. M., Gökkurt, E., Steffens, J. & Stein, A., 2023, In: ONCOL RES TREAT. 46, 7-8, p. 320-325 6 p.Research output: SCORING: Contribution to journal › Case report › Research › peer-review
IL-22BP controls the progression of liver metastasis in colorectal cancer
Giannou, A. D., Kempski, J., Zhang, T., Lücke, J., Shiri, A. M., Zazara, D. E., Belios, I., Machicote, A., Seeger, P., Agalioti, T., Tintelnot, J., Sagebiel, A., Tomczak, M., Bauditz, L., Bedke, T., Kocheise, L., Mercanoglu, B., Fard-Aghaie, M., Giorgakis, E., Lykoudis, P. M., Pikouli, A., Grass, J-K., Wahib, R., Bardenhagen, J., Brunswig, B., Heumann, A., Ghadban, T., Duprée, A., Tachezy, M., Melling, N., Arck, P. C., Stringa, P., Gentilini, M. V., Gondolesi, G. E., Nakano, R., Thomson, A. W., Perez, D., Li, J., Mann, O., Izbicki, J. R., Gagliani, N., Maroulis, I. C. & Huber, S., 2023, In: FRONT ONCOL. 13, p. 1170502Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pembrolizumab and trastuzumab in combination with FLOT in the perioperative treatment of HER2-positive, localized esophagogastric adenocarcinoma-a phase II trial of the AIO study group (AIO STO 0321)
Tintelnot, J., Stein, A., Al-Batran, S-E., Ettrich, T., Götze, T., Grün, B., Haag, G. M., Heuer, V., Hofheinz, R-D., Homann, N., Bröring, T. S., Cruz, M. S., Kurreck, A., Lorenzen, S., Moosmann, N., Müller, C., Schuler, M., Siegler, G., Binder, M. & Gökkurt, E., 2023, In: FRONT ONCOL. 13, p. 1272175Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Efficacy of Ipilimumab vs FOLFOX in Combination With Nivolumab and Trastuzumab in Patients With Previously Untreated ERBB2-Positive Esophagogastric Adenocarcinoma: The AIO INTEGA Randomized Clinical Trial
Stein, A., Paschold, L., Tintelnot, J., Goekkurt, E., Henkes, S-S., Simnica, D., Schultheiss, C., Willscher, E., Bauer, M., Wickenhauser, C., Thuss-Patience, P., Lorenzen, S., Ettrich, T., Riera-Knorrenschild, J., Jacobasch, L., Kretzschmar, A., Kubicka, S., Al-Batran, S-E., Reinacher-Schick, A., Pink, D., Sinn, M., Lindig, U., Hiegl, W., Hinke, A., Hegewisch-Becker, S. & Binder, M., 01.08.2022, In: JAMA ONCOL. 8, 8, p. 1150-1158 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Translational analysis and final efficacy of the AVETUX trial - Avelumab, cetuximab and FOLFOX in metastatic colorectal cancer
Tintelnot, J., Ristow, I., Sauer, M., Simnica, D., Schultheiß, C., Scholz, R., Goekkurt, E., von Wenserski, L., Willscher, E., Paschold, L., Lorenzen, S., Riera-Knorrenschild, J., Depenbusch, R., Ettrich, T. J., Dörfel, S., Al-Batran, S-E., Karthaus, M., Pelzer, U., Hinke, A., Bauer, M., Massa, C., Seliger, B., Wickenhauser, C., Bokemeyer, C., Hegewisch-Becker, S., Binder, M. & Stein, A., 2022, In: FRONT ONCOL. 12, 993611.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
A Phase I dose-escalation study of third-line regorafenib with trifluridine/tipiracil in metastatic colorectal cancer
Moehler, M., Michel, M., Stein, A., Trojan, J., Marquardt, J., Tintelnot, J., Waidmann, O., Weinmann, A., Woerns, M-A., Schroeder, H., Maenz, M. & Foerster, F., 09.2021, In: FUTURE ONCOL. 17, 25, p. 3309-3319 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer
Stein, A., Simnica, D., Schultheiß, C., Scholz, R., Tintelnot, J., Gökkurt, E., von Wenserski, L., Willscher, E., Paschold, L., Sauer, M., Lorenzen, S., Riera-Knorrenschild, J., Depenbusch, R., Ettrich, T. J., Dörfel, S., Al-Batran, S-E., Karthaus, M., Pelzer, U., Waberer, L., Hinke, A., Bauer, M., Massa, C., Seliger, B., Wickenhauser, C., Bokemeyer, C., Hegewisch-Becker, S. & Binder, M., 07.2021, In: J IMMUNOTHER CANCER. 9, 7, e002844.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Ipilimumab or FOLFOX with Nivolumab and Trastuzumab in previously untreated HER2-positive locally advanced or metastatic EsophagoGastric Adenocarcinoma - the randomized phase 2 INTEGA trial (AIO STO 0217)
Tintelnot, J., Goekkurt, E., Binder, M., Thuss-Patience, P., Lorenzen, S., Knorrenschild, J. R., Kretzschmar, A., Ettrich, T., Lindig, U., Jacobasch, L., Pink, D., Al-Batran, S-E., Hinke, A., Hegewisch-Becker, S., Nilsson, S., Bokemeyer, C. & Stein, A., 01.06.2020, In: BMC CANCER. 20, 1, p. 503Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Immunotherapy in colorectal cancer: Available clinical evidence, challenges and novel approaches
Tintelnot, J. & Stein, A., 07.08.2019, In: WORLD J GASTROENTERO. 25, 29, p. 3920-3928 9 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Arc/Arg3.1 defines dendritic cells and Langerhans cells with superior migratory ability independent of phenotype and ontogeny in mice
Tintelnot, J., Ufer, F., Engler, J. B., Winkler, H., Lücke, K., Mittrücker, H-W. & Friese, M. A., 05.2019, In: EUR J IMMUNOL. 49, 5, p. 724-736 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nanobody-targeting of epidermal growth factor receptor (EGFR) ectodomain variants overcomes resistance to therapeutic EGFR antibodies
Tintelnot, J., Baum, N., Schultheiss, C., Braig, F., Trentmann, M., Finter, J., Fumey, W., Bannas, P., Fehse, B., Riecken, K., Schütze, K., Bokemeyer, C., Rösner, T., Valerius, T., Peipp, M., Koch-Nolte, F. & Binder, M., 04.2019, In: MOL CANCER THER. 18, 4, p. 823-833 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer Cells Expressing Oncogenic Rat Sarcoma Show Drug-Addiction Toward Epidermal Growth Factor Receptor Antibodies Mediated by Sustained MAPK Signaling
Tintelnot, J., Metz, S., Trentmann, M., Oberle, A., von Wenserski, L., Schultheiß, C., Braig, F., Kriegs, M., Fehse, B., Riecken, K., Bokemeyer, C., Stein, A. & Binder, M., 2019, In: FRONT ONCOL. 9, p. 1559Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Arc/Arg3.1 governs inflammatory dendritic cell migration from the skin and thereby controls T cell activation
Ufer, F., Vargas, P., Engler, J. B., Tintelnot, J., Schattling, B., Winkler, H., Bauer, S., Kursawe, N., Willing, A., Keminer, O., Ohana, O., Salinas-Riester, G., Pless, O., Kuhl, D. & Friese, M. A., 23.09.2016, In: SCI IMMUNOL. 1, 3, p. eaaf8665Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review