Dr.phil. ID: 1929198
Hariharan Subramanian
Publications
- 2024
Remodelling of cAMP dynamics within the SERCA2a microdomain in heart failure with preserved ejection fraction caused by obesity and type 2 diabetes
Lai, P., Hille, S. S., Subramanian, H., Weigman, R., Roser, P., Müller, O. J., Nikolaev, V. O. & De Jong, K. A., 14.03.2024, In: CARDIOVASC RES. 120, 3, p. 273-285 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multimodal characterization of dilated cardiomyopathy: Geno- And Phenotyping of PrImary Cardiomyopathy (GrAPHIC)
Keil, L., Berisha, F., Ritter, S., Skibowski, J., Subramanian, H., Nikolaev, V. O., Kubisch, C., Woitschach, R., Fabritz, L., Twerenbold, R., Blankenberg, S., Weidemann, S., Zeller, T., Kirchhof, P., Reichart, D. & Magnussen, C., 02.2024, In: ESC HEART FAIL. 11, 1, p. 541-549 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Role of Phosphodiesterase 1 in the Regulation of Real-Time cGMP Levels and Contractility in Adult Mouse Cardiomyocytes
Bork, N. I., Subramanian, H., Kurelic, R., Nikolaev, V. O. & Rybalkin, S. D., 03.12.2023, In: CELLS-BASEL. 12, 23, 2759.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A distinct topology of BTN3A IgV and B30.2 domains controlled by juxtamembrane regions favors optimal human γδ T cell phosphoantigen sensing
Karunakaran, M. M., Subramanian, H., Jin, Y., Mohammed, F., Kimmel, B., Juraske, C., Starick, L., Nöhren, A., Länder, N., Willcox, C. R., Singh, R., Schamel, W. W., Nikolaev, V. O., Kunzmann, V., Wiemer, A. J., Willcox, B. E. & Herrmann, T., 22.11.2023, In: NAT COMMUN. 14, 1, p. 7617Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Microtubule-Mediated Regulation of β2AR Translation and Function in Failing Hearts
Kwan, Z., Paulose Nadappuram, B., Leung, M. M., Mohagaonkar, S., Li, A., Amaradasa, K. S., Chen, J., Rothery, S., Kibreab, I., Fu, J., Sanchez-Alonso, J. L., Mansfield, C. A., Subramanian, H., Kondrashov, A., Wright, P. T., Swiatlowska, P., Nikolaev, V. O., Wojciak-Stothard, B., Ivanov, A. P., Edel, J. B. & Gorelik, J., 10.11.2023, In: CIRC RES. 133, 11, p. 944-958 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CRISPR/Cas9 Knock-Out in Primary Neonatal and Adult Cardiomyocytes Reveals Distinct cAMP Dynamics Regulation by Various PDE2A and PDE3A Isoforms
Skryabin, E. B., De Jong, K. A., Subramanian, H., Bork, N. I., Froese, A., Skryabin, B. V. & Nikolaev, V. O., 04.06.2023, In: CELLS-BASEL. 12, 11, 1543.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A-Kinase Anchoring Proteins in Cardiac Myocytes and Their Roles in Regulating Calcium Cycling
Subramanian, H. & Nikolaev, V. O., 28.01.2023, In: CELLS-BASEL. 12, 3, 436.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2022
A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes
Brandenburg, S., Pawlowitz, J., Steckmeister, V., Subramanian, H., Uhlenkamp, D., Scardigli, M., Mushtaq, M., Amlaz, S. I., Kohl, T., Wegener, J. W., Arvanitis, D. A., Sanoudou, D., Sacconi, L., Hasenfuß, G., Voigt, N., Nikolaev, V. O. & Lehnart, S. E., 04.2022, In: J MOL CELL CARDIOL. 165, p. 141-157 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
Carlson, C. R., Aronsen, J. M., Bergan-Dahl, A., Moutty, M. C., Lunde, M., Lunde, P. K., Jarstadmarken, H., Wanichawan, P., Pereira, L., Kolstad, T. R. S., Dalhus, B., Subramanian, H., Hille, S., Christensen, G., Müller, O. J., Nikolaev, V., Bers, D. M., Sjaastad, I., Shen, X., Louch, W. E., Klussmann, E. & Sejersted, O. M., 07.01.2022, In: CIRC RES. 130, 1, p. 27-44 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
cAMP Imaging at Ryanodine Receptors Reveals β 2-Adrenoceptor Driven Arrhythmias
Berisha, F., Götz, K. R., Wegener, J., Brandenburg, S., Subramanian, H., Molina, C., Rüffer, A., Petersen, J., Bernhardt, A., Girdauskas, E., Jungen, C., Pape, U., Kraft, A., Warnke, S., Lindner, D., Westermann, D., Blankenberg, S., Meyer, C., Hasenfuss, G., Lehnart, S. E. & Nikolaev, V., 25.06.2021, In: CIRC RES. 129, 1, p. 81-94Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP
Subramanian, H., Froese, A., Jönsson, P., Schmidt, H., Gorelik, J. & Nikolaev, V. O., 22.06.2018, In: NAT COMMUN. 9, 1, p. 2446Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity
Donzelli, S., Goetz, M., Schmidt, K., Wolters, M., Stathopoulou, K., Diering, S., Prysyazhna, O., Polat, V., Scotcher, J., Dees, C., Subramanian, H., Butt, E., Kamynina, A., Schobesberger, S., King, S. B., Nikolaev, V. O., de Wit, C., Leichert, L. I., Feil, R., Eaton, P. & Cuello, F., 30.08.2017, In: SCI REP-UK. 7, 1, p. 9938Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Protein kinase A activation by the anti-cancer drugs ABT-737 and thymoquinone is caspase-3-dependent and correlates with platelet inhibition and apoptosis
Rukoyatkina, N., Butt, E., Subramanian, H., Nikolaev, V. O., Mindukshev, I., Walter, U., Gambaryan, S. & Benz, P. M., 29.06.2017, In: CELL DEATH DIS. 8, 6, p. e2898Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Erythrocytes do not activate purified and platelet soluble guanylate cyclases even in conditions favourable for NO synthesis
Gambaryan, S., Subramanian, H., Kehrer, L., Mindukshev, I., Sudnitsyna, J., Reiss, C., Rukoyatkina, N., Friebe, A., Sharina, I., Martin, E. & Walter, U., 11.08.2016, In: CELL COMMUN SIGNAL. 14, 1, p. 16Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PTH1R Mutants Found in Patients with Primary Failure of Tooth Eruption Disrupt G-Protein Signaling
Subramanian, H., Döring, F., Kollert, S., Rukoyatkina, N., Sturm, J., Gambaryan, S., Stellzig-Eisenhauer, A., Meyer-Marcotty, P., Eigenthaler, M. & Wischmeyer, E., 2016, In: PLOS ONE. 11, 11, p. e0167033Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Sildenafil Does Not Prevent Heart Hypertrophy and Fibrosis Induced by Cardiomyocyte Angiotensin II Type 1 Receptor Signaling
Straubinger, J., Schöttle, V., Bork, N., Subramanian, H., Dünnes, S., Russwurm, M., Gawaz, M., Friebe, A., Nemer, M., Nikolaev, V. O. & Lukowski, R., 09.2015, In: J PHARMACOL EXP THER. 354, 3, p. 406-16 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adenylyl cyclases 5 and 6 underlie PIP3-dependent regulation
Reddy, G. R., Subramanian, H., Birk, A., Milde, M., Nikolaev, V. O. & Bünemann, M., 08.2015, In: FASEB J. 29, 8, p. 3458-71 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review