Felix von Brackel
Publications
- 2024
Biopsies from patients with sacral insufficiency fracture are characterized by low bone matrix mineralization and high turnover
Delsmann, M. M., Leonhardt, L-G., Alimy, A-R., Hoenig, T., Beil, F. T., Püschel, K., von Brackel, F. N., Amling, M., Viezens, L., Thiesen, D. M. & Rolvien, T., 09.2024, In: JBMR PLUS. 8, 9, p. ziae094Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Osteomodulin deficiency in mice causes a specific reduction of transversal cortical bone size
Zhao, W., von Kroge, S., Jadzic, J., Milovanovic, P., Sihota, P., Luther, J., Brylka, L., von Brackel, F. N., Bockamp, E., Busse, B., Amling, M., Schinke, T. & Schinke, T., 05.08.2024, In: J BONE MINER RES. 39, 7, p. 1025-1041 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pronounced cortical porosity and sex-specific patterns of increased bone and osteocyte lacunar mineralization characterize the human distal fibula with aging
Hering, R-N., von Kroge, S., Delsmann, J., Simon, A., Ondruschka, B., Püschel, K., Schmidt, F. N. & Rolvien, T., 05.2024, In: BONE. 182, p. 117068Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Approaching virtual osteoid volume estimation and in-depth tissue characterization in patients with tumor-induced Osteomalacia
Schmidt, F. N., Delsmann, J., Yazigi, B., Beil, F. T., Amling, M. & Oheim, R., 22.03.2024, In: J BONE MINER RES. 39, 2, p. 116-129 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lower microhardness along with less heterogeneous mineralization in the femoral neck of individuals with type 2 diabetes mellitus indicates higher fracture risk
Cirovic, A., Schmidt, F. N., Vujacic, M., Sihota, P., Petrovic, B., Zivkovic, V., Bascarevic, Z., Nikolic, S., Djonic, D., Djuric, M., Busse, B. & Milovanovic, P., 03.2024, In: JBMR PLUS. 8, 3, p. ziae005Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Comparison of Motion Grading in 1,000 Patients by First- and Second-Generation HR-pQCT: A Propensity Score Matched Cohort Study
Bartosik, M., Simon, A., Strahl, A., Oheim, R., Amling, M. & Schmidt, F. N., 12.2023, In: CALCIFIED TISSUE INT. 113, 6, p. 597-608 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
When Cortical Bone Matrix Properties Are Indiscernible between Elderly Men with and without Type 2 Diabetes, Fracture Resistance Follows Suit
Wölfel, E. M., Bartsch, B., Koldehoff, J., Fiedler, I. A. K., Dragoun-Kolibova, S., Schmidt, F. N., Krug, J., Lin, M-C., Püschel, K., Ondruschka, B., Zimmermann, E. A., Jelitto, H., Schneider, G., Gludovatz, B. & Busse, B., 12.2023, In: JBMR PLUS. 7, 12, p. e10839Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease
Mellor, L. F., Gago-Lopez, N., Bakiri, L., Schmidt, F. N., Busse, B., Rauber, S., Jimenez, M., Megías, D., Oterino-Soto, S., Sanchez-Prieto, R., Grivennikov, S., Pu, X., Oxford, J., Ramming, A., Schett, G. & Wagner, E. F., 18.10.2023, In: ANN RHEUM DIS. 81, 10, p. 1400-1408 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Zinc and vitamin D deficiency and supplementation in hypophosphatasia patients: A retrospective study
Wiedemann, P., Schmidt, F. N., Amling, M., Yorgan, T. A. & Barvencik, F., 10.2023, In: BONE. 175, 116849.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Radial HR-pQCT and Finite Element Analysis in HPP Patients are Superior in Identifying Susceptibility to Fracture-Associated Skeletal Affections Compared to DXA and Laboratory Tests
Schmidt, F. N., Schmidt, C., Delsmann, J., Amling, M. & Barvencik, F., 06.2023, In: CALCIFIED TISSUE INT. 112, 6, p. 691-703 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
On the fracture behavior of cortical bone microstructure: The effects of morphology and material characteristics of bone structural components
Allahyari, P., Silani, M., Yaghoubi, V., Milovanovic, P., Schmidt, F. N., Busse, B. & Qwamizadeh, M., 01.2023, In: J MECH BEHAV BIOMED. 137, 105530.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Dimorphic mechanisms of fragility in diabetes mellitus - the role of reduced collagen fibril deformation
Wölfel, E. M., Schmidt, F. N., Vom Scheidt, A., Siebels, A. K., Wulff, B., Mushumba, H., Ondruschka, B., Püschel, K., Scheijen, J., Schalkwijk, C. G., Vettorazzi, E., Jähn-Rickert, K., Gludovatz, B., Schaible, E., Amling, M., Rauner, M., Hofbauer, L. C., Zimmermann, E. A. & Busse, B., 11.2022, In: J BONE MINER RES. 37, 11, p. 2259-2276 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Compartment-specific effects of muscle strength on bone microarchitecture in women at high risk of osteoporosis
Simon, A., Schäfer, H. S., Schmidt, F. N., Stürznickel, J., Amling, M. & Rolvien, T., 10.2022, In: J CACHEXIA SARCOPENI. 13, 5, p. 2310-2321 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Superior Bone Microarchitecture in Anatomic Versus Nonanatomic Fibular Drill Tunnels for Reconstruction of the Posterolateral Corner of the Knee
Stürznickel, J., Schmidt, F. N., Schweizer, C., Mushumba, H., Krause, M., Püschel, K. & Rolvien, T., 09.2022, In: ORTHOP J SPORTS MED. 10, 9, 23259671221126475.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human engineered heart tissue transplantation in a guinea pig chronic injury model
von Bibra, C., Shibamiya, A., Geertz, B., Querdel, E., Köhne, M., Stüdemann, T., Starbatty, J., Schmidt, F. N., Hansen, A., Hiebl, B., Eschenhagen, T. & Weinberger, F., 23.01.2022, In: J MOL CELL CARDIOL. 166, p. 1-10 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Influence of X-rays and gamma-rays on the mechanical performance of human bone factoring out intraindividual bone structure and composition indices
Schmidt, F. N., Hahn, M., Stockhausen, K. E., Rolvien, T., Schmidt, C., Knopp, T., Schulze, C., Püschel, K., Amling, M. & Busse, B., 01.2022, In: MATER TODAY BIO. 13, 100169.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Conductive hearing loss in the Hyp mouse model of X-linked hypophosphatemia is accompanied by hypomineralization of the auditory ossicles
Delsmann, M. M., Seist, R., Stürznickel, J., Schmidt, F. N., Mansour, A., Kobelski, M. M., Broocks, G., Peichl, J., Oheim, R., Praetorius, M., Schinke, T., Amling, M., Demay, M. B., Stankovic, K. M. & Rolvien, T., 12.2021, In: J BONE MINER RES. 36, 12, p. 2317-2328 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The WNT1G177C mutation specifically affects skeletal integrity in a mouse model of osteogenesis imperfecta type XV
Vollersen, N., Zhao, W., Rolvien, T., Lange, F., Schmidt, F. N., Sonntag, S., Shmerling, D., von Kroge, S., Stockhausen, K. E., Sharaf, A., Schweizer, M., Karsak, M., Busse, B., Bockamp, E., Semler, O., Amling, M., Oheim, R., Schinke, T. & Yorgan, T. A., 10.11.2021, In: BONE RES. 9, 1, p. 48Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone microarchitecture of the distal fibula assessed by HR-pQCT
Stürznickel, J., Schmidt, F. N., Schäfer, H. S., Beil, F. T., Frosch, K-H., Schlickewei, C., Amling, M., Barg, A. & Rolvien, T., 10.2021, In: BONE. 151, 116057.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Loss of glucocorticoid rhythm induces an osteoporotic phenotype in female mice
Schilperoort, M., Kroon, J., Kooijman, S., Smit, A. E., Gentenaar, M., Mletzko, K., Schmidt, F. N., van Ruijven, L., Busse, B., Pereira, A. M., Appelman-Dijkstra, N. M., Bravenboer, N., Rensen, P. C. N., Meijer, O. C. & Winter, E. M., 10.2021, In: AGING CELL. 20, 10, e13474.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Silk Fiber-Reinforced Hyaluronic Acid-Based Hydrogel for Cartilage Tissue Engineering
Weitkamp, J-T., Wöltje, M., Nußpickel, B., Schmidt, F. N., Aibibu, D., Bayer, A., Eglin, D., Armiento, A. R., Arnold, P., Cherif, C., Lucius, R., Smeets, R., Kurz, B. & Behrendt, P., 31.03.2021, In: INT J MOL SCI. 22, 7, 3635.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevance of in-depth skeletal assessment by high-resolution peripheral quantitative computed tomography (HR-pQCT) in orthopedics and trauma surgery
Stürznickel, J. & Schmidt, F., 10.03.2021, In: Fuß & Sprunggelenk. 19, 1, p. 19-26Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Bone healing and reactivation of remodeling under asfotase alfa therapy in adult patients with pediatric-onset hypophosphatasia
Stürznickel, J., Schmidt, F. N., von Vopelius, E., Delsmann, M. M., Schmidt, C., Jandl, N. M., Oheim, R. & Barvencik, F., 02.2021, In: BONE. 143, p. 115794Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High-throughput lossy-to-lossless 3D image compression
Rossinelli, D., Fourestey, G., Schmidt, F., Busse, B. & Kurtcuoglu, V., 02.2021, In: IEEE T MED IMAGING. 40, 2, p. 607-620 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Collagen Fiber Orientation Is Coupled with Specific Nano-Compositional Patterns in Dark and Bright Osteons Modulating Their Biomechanical Properties
Stockhausen, K. E., Qwamizadeh, M., Wölfel, E. M., Hemmatian, H., Fiedler, I. A. K., Flenner, S., Longo, E., Amling, M., Greving, I., Ritchie, R. O., Schmidt, F. N. & Busse, B., 26.01.2021, In: ACS NANO. 15, 1, p. 455-467 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Individuals with type 2 diabetes mellitus show dimorphic and heterogeneous patterns of loss in femoral bone quality
Wölfel, E. M., Jähn-Rickert, K., Schmidt, F. N., Wulff, B., Mushumba, H., Sroga, G. E., Püschel, K., Milovanovic, P., Amling, M., Campbell, G. M., Vashishth, D. & Busse, B., 11.2020, In: BONE. 140, p. 115556Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-term immobilization in elderly females causes a specific pattern of cortical bone and osteocyte deterioration different from postmenopausal osteoporosis
Rolvien, T., Milovanovic, P., Schmidt, F. N., von Kroge, S., Wölfel, E. M., Krause, M., Wulff, B., Püschel, K., Ritchie, R. O., Amling, M. & Busse, B., 07.2020, In: J BONE MINER RES. 35, 7, p. 1343-1351 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A clinical perspective on advanced developments in bone biopsy assessment in rare bone disorders
Treurniet, S., Eekhoff, EMW., Schmidt, F. N., Micha, D., Busse, B. & Bravenboer, N., 2020, In: FRONT ENDOCRINOL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Recovery of bone mineralization and quality during asfotase alfa treatment in an adult patient with infantile-onset hypophosphatasia
Rolvien, T., Schmidt, T., Schmidt, F. N., von Kroge, S., Busse, B., Amling, M. & Barvencik, F., 10.2019, In: BONE. 127, p. 67-74 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mechanical Competence and Bone Quality Develop During Skeletal Growth
Zimmermann, E. A., Riedel, C., Schmidt, F. N., Stockhausen, K. E., Chushkin, Y., Schaible, E., Gludovatz, B., Vettorazzi, E., Zontone, F., Püschel, K., Amling, M., Ritchie, R. O. & Busse, B., 08.2019, In: J BONE MINER RES. 34, 8, p. 1461-1472 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
On the Origins of Fracture Toughness in Advanced Teleosts: How the Swordfish Sword's Bone Structure and Composition Allow for Slashing under Water to Kill or Stun Prey
Schmidt, F. N., Zimmermann, E. A., Walsh, F., Plumeyer, C., Schaible, E., Fiedler, I. A. K., Milovanovic, P., Rößle, M., Amling, M., Blanchet, C., Gludovatz, B., Ritchie, R. O. & Busse, B., 19.06.2019, In: ADV SCI. 6, 12, p. 1900287Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Collagen Fibril Plasticity is altered in Individuals with Type 2 Diabetes Mellitus and non-osteoporotic Bone Mineral Density
Woelfel, E. M., Siebels, A. K., Ma, L-Y., vom Scheidt, A., Schmidt, F. N., Amling, M., Jaehn, K., Busse, B., Zimmermann, E., Wulff, B., Mushumba, H., Püschel, K. & Schaible, E., 2019, In: J BONE MINER RES. 34, Suppl 1Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
- 2018
Ultra-high matrix mineralization of sperm whale auditory ossicles facilitates high sound pressure and high-frequency underwater hearing
Schmidt, F. N., Delsmann, M. M., Mletzko, K., Yorgan, T. A., Hahn, M., Siebert, U., Busse, B., Oheim, R., Amling, M. & Rolvien, T., 19.12.2018, In: P ROY SOC B-BIOL SCI. 285, 1893, p. 20181820 1 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of Bone Microarchitecture Between Adult Osteogenesis Imperfecta and Early-Onset Osteoporosis
Rolvien, T., Stürznickel, J., Schmidt, F. N., Butscheidt, S., Schmidt, T., Busse, B., Mundlos, S., Schinke, T., Kornak, U., Amling, M. & Oheim, R., 11.2018, In: CALCIFIED TISSUE INT. 103, 5, p. 512-521 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Differential effects of high-fat diet and exercise training on bone and energy metabolism
Picke, A-K., Sylow, L., Møller, L. L. V., Kjøbsted, R., Schmidt, F. N., Steejn, M. W., Salbach-Hirsch, J., Hofbauer, C., Blüher, M., Saalbach, A., Busse, B., Rauner, M. & Hofbauer, L. C., 11.2018, In: BONE. 116, p. 120-134 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Thy-1 (CD90) promotes bone formation and protects against obesity
Picke, A-K., Campbell, G. M., Blüher, M., Krügel, U., Schmidt, F. N., Tsourdi, E., Winzer, M., Rauner, M., Vukicevic, V., Busse, B., Salbach-Hirsch, J., Tuckermann, J. P., Simon, J. C., Anderegg, U., Hofbauer, L. C. & Saalbach, A., 08.08.2018, In: SCI TRANSL MED. 10, 453, p. eaao6806Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Severely Impaired Bone Material Quality in Chihuahua Zebrafish Resembles Classical Dominant Human Osteogenesis Imperfecta
Fiedler, I. A. K., Schmidt, F. N., Wölfel, E. M., Plumeyer, C., Milovanovic, P., Gioia, R., Tonelli, F., Bale, H. A., Jähn, K., Besio, R., Forlino, A. & Busse, B., 08.2018, In: J BONE MINER RES. 33, 8, p. 1489-1499 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Autologous bridging of rotator cuff tears with a hamstring tendon patch. A cadaver feasibility study and biomechanical testing
Kircher, J., Schmidt, F., Hawellek, T., Hubert, J., Hedtmann, A., Püschel, K., Hahn, M. & Niemeier, A., 07.2018, In: CLIN BIOMECH. 56, p. 36-39 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disease duration and stage influence bone microstructure in patients with primary biliary cholangitis
Schmidt, T., Schmidt, C., Schmidt, F. N., Butscheidt, S., Mussawy, H., Hubert, J., Hawellek, T., Oehler, N., Barvencik, F., Lohse, A. W., Schinke, T., Schramm, C., Amling, M. & Rolvien, T., 06.2018, In: J BONE MINER RES. 33, 6, p. 1011-1019 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Perturbed bone composition and integrity with disorganized osteoblast function in zinc receptor/Gpr39-deficient mice
Jovanovic, M., Schmidt, F. N., Guterman-Ram, G., Khayyeri, H., Hiram-Bab, S., Orenbuch, A., Katchkovsky, S., Aflalo, A., Isaksson, H., Busse, B., Jähn, K. & Levaot, N., 05.2018, In: FASEB J. 32, 5, p. 2507-2518 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Early bone tissue aging in human auditory ossicles is accompanied by excessive hypermineralization, osteocyte death and micropetrosis
Rolvien, T., Schmidt, F. N., Milovanovic, P., Jähn, K., Riedel, C., Butscheidt, S., Püschel, K., Jeschke, A., Amling, M. & Busse, B., 30.01.2018, In: SCI REP-UK. 8, 1, p. 1920Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical Significance of DXA and HR-pQCT in Autosomal Dominant Osteopetrosis (ADO II)
Butscheidt, S., Rolvien, T., Kornak, U., Schmidt, F. N., Schinke, T., Amling, M. & Oheim, R., 01.2018, In: CALCIFIED TISSUE INT. 102, 1, p. 41-52 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Thy-1 Deficiency Augments Bone Loss in Obesity by Affecting Bone Formation and Resorption
Picke, A-K., Campbell, G. M., Schmidt, F. N., Busse, B., Rauner, M., Simon, J. C., Anderegg, U., Hofbauer, L. C. & Saalbach, A., 2018, In: FRONT CELL DEV BIOL. 6, p. 127Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Changes in cortical microarchitecture are independent of areal bone mineral density in patients with fragility fractures
Mussawy, H., Ferrari, G., Schmidt, F. N., Schmidt, T., Rolvien, T., Hischke, S., Rüther, W. & Amling, M., 11.2017, In: INJURY. 48, 11, p. 2461-2465Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Assessment of collagen quality associated with non-enzymatic cross-links in human bone using Fourier-transform infrared imaging
Schmidt, F. N., Zimmermann, E. A., Campbell, G. M., Sroga, G. E., Püschel, K., Amling, M., Tang, S. Y., Vashishth, D. & Busse, B., 04.2017, In: BONE. 97, p. 243-251 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Defining Restrictions and Limits of Registration-Based Quantification of Geometric Deformation in Cerebral Blood Vessels
Schetelig, D., Sedlacik, J., Schmidt, F. N., Fiehler, J. & Werner, R., 2017, Bildverarbeitung für die Medizin 2017: Algorithmen - Systeme - Anwendungen. Maier-Hain, K. H., Deserno, T., Handels, H. & Tolxdorff, T. (eds.). 1 ed. Springer, p. 191-196 6 p. (Informatik aktuell).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Significance of DXA and HR-pQCT for the Diagnosis of Osteopetrosis (ADO II)-Establishment of a Diagnostic Threshold.
Butscheidt, S., Rolvien, T., Kornak, U., Schmidt, F. N., Schinke, T., Amling, M. & Oheim, R., 2017, In: J BONE MINER RES. 32, p. S167-S167Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
- 2016
How the European eel (Anguilla anguilla) loses its skeletal framework across lifetime
Rolvien, T., Nagel, F., Milovanovic, P., Wuertz, S., Marshall, R. P., Jeschke, A., Schmidt, F. N., Hahn, M., Witten, P. E., Amling, M. & Busse, B., 26.10.2016, In: P ROY SOC B-BIOL SCI. 283, 1841, p. pii: 20161550Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intrinsic mechanical behavior of femoral cortical bone in young, osteoporotic and bisphosphonate-treated individuals in low- and high energy fracture conditions
Zimmermann, E. A., Schaible, E., Gludovatz, B., Schmidt, F. N., Riedel, C., Krause, M., Vettorazzi, E., Acevedo, C., Hahn, M., Püschel, K., Tang, S., Amling, M., Ritchie, R. O. & Busse, B., 16.02.2016, In: SCI REP-UK. 6, p. 21072Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Assessment of changes in collagen associated with advanced glycation end-products in human bone using vibrational spectroscopy
Schmidt, F. N., Zimmermann, E. A., Puschel, K., Amling, M., Vashishth, D., Tang, S. & Busse, B., 2016, Bone Abstracts. Vol. 5. p. P33Research output: SCORING: Contribution to book/anthology › Conference contribution - Published abstract for conference with selection process › Research › peer-review