Research ExplorerScientific StaffChristoffer Gebhardt Publications

Univ. Prof. Dr. ID: 5526253

Christoffer Gebhardt

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ORCID: 0000-0001-7090-9584
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Publications

  1. 2019

  2. Tumor microenvironment-derived S100A8/A9 is a novel prognostic biomarker for advanced melanoma patients and during immunotherapy with anti-PD-1 antibodies

    Wagner, NB., Weide, B., Gries, M., Reith, M., Tarnanidis, K., Schuermans, V., Kemper, C., Kehrel, C., Funder, A., Lichtenberger, R., Sucker, A., Herpel, E., Holland-Letz, T. & Gebhardt, C., 12.2019, In: J IMMUNOTHER CANCER. 2019, 7, 343.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. 46th annual congress of the "Arbeitsgemeinschaft Dermatologische Forschung" in Munich, Germany.

    Gaffal, E., Eming, R., Fabri, M., Gebhardt, C., Stary, G., Eyerich, S., Hölzel, M., Kosnopfel, C., Neubert, E., Rauer, D., Rodríguez, E., Thiem, A., von, M. L. & Buhl, T., 09.2019, In: EXP DERMATOL.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Deep learning outperformed 136 of 157 dermatologists in a head-to-head dermoscopic melanoma image classification task

    Brinker, T. J., Hekler, A., Enk, A. H., Klode, J., Hauschild, A., Berking, C., Schilling, B., Haferkamp, S., Schadendorf, D., Holland-Letz, T., Utikal, J. S., von Kalle, C. & Collaborators, 05.2019, In: EUR J CANCER. 113, p. 47-54 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. First-line therapy-stratified survival in BRAF-mutant melanoma: a retrospective multicenter analysis

    Schilling, B., Martens, A., Geukes Foppen, M. H., Gebhardt, C., Hassel, J. C., Rozeman, E. A., Gesierich, A., Gutzmer, R., Kähler, K. C., Livingstone, E., Diamantopoulos, P. T., Gogas, H., Madonna, G., Ascierto, P. A., Goldinger, S. M., Mangana, J., Garbe, C., Schadendorf, D., Blank, C. & Weide, B., 05.2019, In: CANCER IMMUNOL IMMUN. 68, 5, p. 765-772 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Expression of Neural Crest Markers GLDC and ERRFI1 is Correlated with Melanoma Prognosis

    Jäger, K., Larribère, L., Wu, H., Weiss, C., Gebhardt, C. & Utikal, J., 11.01.2019, In: CANCERS. 11, 1

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. 2018

  8. 45th meeting of the Arbeitsgemeinschaft Dermatologische Forschung

    Loser, K., Eming, R., Eyerich, K., Gebhardt, C., Ludwig, R., Baghin, V., Baurecht, H., Forsthuber, A., Glodde, N., Schmidt, E., Schmidt, T., Shridhar, N., Simon, B. & Gaffal, E., 07.2018, In: EXP DERMATOL. 27, 7, p. 798-802 5 p.

    Research output: SCORING: Contribution to journal › Conference article in journal › Research › peer-review

  9. STAT5 expression correlates with recurrence and survival in melanoma patients treated with interferon-α

    Machiraju, D., Moll, I., Gebhardt, C., Sucker, A., Buder-Bakhaya, K., Schadendorf, D. & Hassel, J. C., 06.2018, In: MELANOMA RES. 28, 3, p. 204-210 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Liquid Profiling of Circulating Tumor DNA in Plasma of Melanoma Patients for Companion Diagnostics and Monitoring of BRAF Inhibitor Therapy

    Haselmann, V., Gebhardt, C., Brechtel, I., Duda, A., Czerwinski, C., Sucker, A., Holland-Letz, T., Utikal, J., Schadendorf, D. & Neumaier, M., 05.2018, In: CLIN CHEM. 64, 5, p. 830-842 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Extracorporal Shock Wave Therapy Enhances Receptor for Advanced Glycated End-Product-Dependent Flap Survival and Angiogenesis

    Birgin, E., Gebhardt, C., Hetjens, S., Fischer, S., Rückert, F. & Reichenberger, M. A., 04.2018, In: ANN PLAS SURG. 80, 4, p. 424-431 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Liquid biopsy to monitor melanoma patients

    Gaiser, M. R., von Bubnoff, N., Gebhardt, C. & Utikal, J. S., 04.2018, In: J DTSCH DERMATOL GES. 16, 4, p. 405-414 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  13. Liquid Biopsy zur Überwachung von Melanompatienten.

    Gaiser, MR., von, B. N., Gebhardt, C. & Utikal, JS., 04.2018, In: J DTSCH DERMATOL GES.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Multiple epidermotropic melanoma metastases developing during BRAF and MEK inhibitor therapy

    Reinhard, R., Gebhardt, C., Maurier, N., Larribère, L., Orouji, A. & Utikal, J., 03.2018, In: JAAD Case Rep. 4, 2, p. 129-131 3 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. CCR5+ Myeloid-Derived Suppressor Cells Are Enriched and Activated in Melanoma Lesions

    Blattner, C., Fleming, V., Weber, R., Himmelhan, B., Altevogt, P., Gebhardt, C., Schulze, T. J., Razon, H., Hawila, E., Wildbaum, G., Utikal, J., Karin, N. & Umansky, V., 01.01.2018, In: CANCER RES. 78, 1, p. 157-167 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. 2017

  17. The shedded ectodomain of Lyve-1 expressed on M2-like tumorassociated macrophages inhibits melanoma cell proliferation

    Dollt, C., Becker, K., Michel, J., Melchers, S., Weis, C-A., Schledzewski, K., Krewer, A., Kloss, L., Gebhardt, C., Utikal, J. & Schmieder, A., 28.11.2017, In: ONCOTARGET. 8, 61, p. 103682-103692 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy

    Glodde, N., Bald, T., van den Boorn-Konijnenberg, D., Nakamura, K., O'Donnell, J. S., Szczepanski, S., Brandes, M., Eickhoff, S., Das, I., Shridhar, N., Hinze, D., Rogava, M., van der Sluis, T. C., Ruotsalainen, J. J., Gaffal, E., Landsberg, J., Ludwig, K. U., Wilhelm, C., Riek-Burchardt, M., Müller, A. J., Gebhardt, C., Scolyer, R. A., Long, G. V., Janzen, V., Teng, M. W. L., Kastenmüller, W., Mazzone, M., Smyth, M. J., Tüting, T. & Hölzel, M., 17.10.2017, In: IMMUNITY. 47, 4, p. 789-802.e9

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair

    Kumar, V., Fleming, T., Terjung, S., Gorzelanny, C., Gebhardt, C., Agrawal, R., Mall, M. A., Ranzinger, J., Zeier, M., Madhusudhan, T., Ranjan, S., Isermann, B., Liesz, A., Deshpande, D., Häring, H-U., Biswas, S. K., Reynolds, P. R., Hammes, H-P., Peperkok, R., Angel, P., Herzig, S. & Nawroth, P. P., 13.10.2017, In: NUCLEIC ACIDS RES. 45, 18, p. 10595-10613 19 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. CCR5 in recruitment and activation of myeloid-derived suppressor cells in melanoma

    Umansky, V., Blattner, C., Gebhardt, C. & Utikal, J., 08.2017, In: CANCER IMMUNOL IMMUN. 66, 8, p. 1015-1023 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  21. Recurrent tattoo reactions in a patient treated with BRAF and MEK inhibitors

    Reinhard, R., Gebhardt, C., Schmieder, A., Umansky, V. & Utikal, J., 08.2017, In: J EUR ACAD DERMATOL. 31, 8, p. e375-e377

    Research output: SCORING: Contribution to journal › Letter › Research › peer-review

  22. Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

    Sahin, U., Derhovanessian, E., Miller, M., Kloke, B-P., Simon, P., Löwer, M., Bukur, V., Tadmor, A. D., Luxemburger, U., Schrörs, B., Omokoko, T., Vormehr, M., Albrecht, C., Paruzynski, A., Kuhn, A. N., Buck, J., Heesch, S., Schreeb, K. H., Müller, F., Ortseifer, I., Vogler, I., Godehardt, E., Attig, S., Rae, R., Breitkreuz, A., Tolliver, C., Suchan, M., Martic, G., Hohberger, A., Sorn, P., Diekmann, J., Ciesla, J., Waksmann, O., Brück, A-K., Witt, M., Zillgen, M., Rothermel, A., Kasemann, B., Langer, D., Bolte, S., Diken, M., Kreiter, S., Nemecek, R., Gebhardt, C., Grabbe, S., Höller, C., Utikal, J., Huber, C., Loquai, C. & Türeci, Ö., 13.07.2017, In: NATURE. 547, 7662, p. 222-226 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response

    Bernhardt, M., Novak, D., Assenov, Y., Orouji, E., Knappe, N., Weina, K., Reith, M., Larribere, L., Gebhardt, C., Plass, C., Umansky, V. & Utikal, J., 09.05.2017, In: STEM CELL REP. 8, 5, p. 1379-1391 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Sentinel node metastasis mitotic rate (SN-MMR) as a prognostic indicator of rapidly progressing disease in patients with sentinel node-positive melanomas

    Baum, C., Weiss, C., Gebhardt, C., Utikal, J., Marx, A., Koenen, W. & Géraud, C., 15.04.2017, In: INT J CANCER. 140, 8, p. 1907-1917 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Myeloid-derived suppressor cells and tumor escape from immune surveillance

    Umansky, V., Blattner, C., Fleming, V., Hu, X., Gebhardt, C., Altevogt, P. & Utikal, J., 04.2017, In: SEMIN IMMUNOPATHOL. 39, 3, p. 295-305 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  26. Endothelial Notch1 Activity Facilitates Metastasis

    Wieland, E., Rodriguez-Vita, J., Liebler, S. S., Mogler, C., Moll, I., Herberich, S. E., Espinet, E., Herpel, E., Menuchin, A., Chang-Claude, J., Hoffmeister, M., Gebhardt, C., Brenner, H., Trumpp, A., Siebel, C. W., Hecker, M., Utikal, J., Sprinzak, D. & Fischer, A., 13.03.2017, In: CANCER CELL. 31, 3, p. 355-367 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. D-dimers in malignant melanoma: Association with prognosis and dynamic variation in disease progress

    Desch, A., Gebhardt, C., Utikal, J. & Schneider, S. W., 15.02.2017, In: INT J CANCER. 140, 4, p. 914-921 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Role of mutational status of GNAQ and GNA11 in the diagnosis of melanocytic tumors: Response

    Griewank, K. G., Koelsche, C., Wenz, F., Giordano, F. A. & Gebhardt, C., 2017, In: J NEUROSURG.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. 2016

  30. Baseline Biomarkers for Outcome of Melanoma Patients Treated with Pembrolizumab

    Weide, B., Martens, A., Hassel, J. C., Berking, C., Postow, M. A., Bisschop, K., Simeone, E., Mangana, J., Schilling, B., Di Giacomo, A. M., Brenner, N., Kähler, K., Heinzerling, L., Gutzmer, R., Bender, A., Gebhardt, C., Romano, E., Meier, F., Martus, P., Maio, M., Blank, C., Schadendorf, D., Dummer, R., Ascierto, P. A., Hospers, G., Garbe, C. & Wolchok, J. D., 15.11.2016, In: CLIN CANCER RES. 22, 22, p. 5487-5496 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. The Role of Myeloid-Derived Suppressor Cells (MDSC) in Cancer Progression

    Umansky, V., Blattner, C., Gebhardt, C. & Utikal, J., 03.11.2016, In: VACCINES-BASEL. 4, 4

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  32. Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages

    Huber, R., Meier, B., Otsuka, A., Fenini, G., Satoh, T., Gehrke, S., Widmer, D., Levesque, M. P., Mangana, J., Kerl, K., Gebhardt, C., Fujii, H., Nakashima, C., Nonomura, Y., Kabashima, K., Dummer, R., Contassot, E. & French, L. E., 18.07.2016, In: SCI REP-UK. 6, p. 29914

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. TGF-β induces SOX2 expression in a time-dependent manner in human melanoma cells

    Weina, K., Wu, H., Knappe, N., Orouji, E., Novak, D., Bernhardt, M., Hüser, L., Larribère, L., Umansky, V., Gebhardt, C. & Utikal, J., 07.2016, In: PIGM CELL MELANOMA R. 29, 4, p. 453-458 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. The GNAQ in the haystack: intramedullary meningeal melanocytoma of intermediate grade at T9-10 in a 58-year-old woman

    Hoffmann, M., Koelsche, C., Seiz-Rosenhagen, M., Mai, S., Lohr, F., Reuss, D., Wenz, F., Gebhardt, C. & Giordano, F. A., 07.2016, In: J NEUROSURG. 125, 1, p. 53-56 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Predictive immune markers in advanced melanoma patients treated with ipilimumab

    Umansky, V., Utikal, J. & Gebhardt, C., 06.2016, In: ONCOIMMUNOLOGY. 5, 6, p. e1158901

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. MAP kinase pathway gene copy alterations in NRAS/BRAF wild-type advanced melanoma

    Orouji, E., Orouji, A., Gaiser, T., Larribère, L., Gebhardt, C. & Utikal, J., 01.05.2016, In: INT J CANCER. 138, 9, p. 2257-62 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Directed Dedifferentiation Using Partial Reprogramming Induces Invasive Phenotype in Melanoma Cells

    Knappe, N., Novak, D., Weina, K., Bernhardt, M., Reith, M., Larribere, L., Hölzel, M., Tüting, T., Gebhardt, C., Umansky, V. & Utikal, J., 04.2016, In: Stem cells (Dayton, Ohio). 34, 4, p. 832-46 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Biomarker value and pitfalls of serum S100B in the follow-up of high-risk melanoma patients

    Gebhardt, C., Lichtenberger, R. & Utikal, J., 02.2016, In: J DTSCH DERMATOL GES. 14, 2, p. 158-64 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Neural crest-like gene FOXD1 plays a role in melanoma cell migration and invasion

    Gebhardt, C., 2016

    Research output: Other contribution › Other › Research

  40. 2015

  41. Myeloid Cells and Related Chronic Inflammatory Factors as Novel Predictive Markers in Melanoma Treatment with Ipilimumab

    Gebhardt, C., Sevko, A., Jiang, H., Lichtenberger, R., Reith, M., Tarnanidis, K., Holland-Letz, T., Umansky, L., Beckhove, P., Sucker, A., Schadendorf, D., Utikal, J. & Umansky, V., 15.12.2015, In: CLIN CANCER RES. 21, 24, p. 5453-9 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Diminished levels of the soluble form of RAGE are related to poor survival in malignant melanoma

    Wagner, N. B., Weide, B., Reith, M., Tarnanidis, K., Kehrel, C., Lichtenberger, R., Pflugfelder, A., Herpel, E., Eubel, J., Ikenberg, K., Busch, C., Holland-Letz, T., Naeher, H., Garbe, C., Umansky, V., Enk, A., Utikal, J. & Gebhardt, C., 01.12.2015, In: INT J CANCER. 137, 11, p. 2607-17 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. T cell responses in early-stage melanoma patients occur frequently and are not associated with humoral response

    Pfirschke, C., Gebhardt, C., Zörnig, I., Pritsch, M., Eichmüller, S. B., Jäger, D., Enk, A. & Beckhove, P., 11.2015, In: CANCER IMMUNOL IMMUN. 64, 11, p. 1369-81 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Elevated chronic inflammatory factors and myeloid-derived suppressor cells indicate poor prognosis in advanced melanoma patients

    Jiang, H., Gebhardt, C., Umansky, L., Beckhove, P., Schulze, T. J., Utikal, J. & Umansky, V., 15.05.2015, In: INT J CANCER. 136, 10, p. 2352-60 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Complete remission of treatment-refractory advanced angiosarcoma of the scalp by protracted intralesional interleukin-2 therapy

    Gebhardt, C., Ziegler, B., Stadler, S., Goerdt, S. & Utikal, J., 04.2015, In: BRIT J DERMATOL. 172, 4, p. 1156-8 3 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. New therapeutic options for advanced non-resectable malignant melanoma

    Stadler, S., Weina, K., Gebhardt, C. & Utikal, J., 03.2015, In: ADV MED SCI-POLAND. 60, 1, p. 83-8 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  47. Multiple white cysts on face and trunk of a melanoma patient treated with vemurafenib

    Gebhardt, C., Staub, J., Schmieder, A., Goerdt, S. & Utikal, J., 01.2015, In: ACTA DERM-VENEREOL. 95, 1, p. 96-7 2 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. An unusual case with multiple epidermotropic melanoma metastases developing under combination therapy with dabrafenib and trametinib

    Gebhardt, C., 2015, In: J DTSCH DERMATOL GES.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. 2014

  50. Leukocyte count restoration under dabrafenib treatment in a melanoma patient with vemurafenib-induced leukopenia: case report

    Orouji, E., Ziegler, B., Umansky, V., Gebhardt, C. & Utikal, J., 12.2014, In: MEDICINE. 93, 28, p. e161

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. Myeloid-derived suppressor cells in malignant melanoma

    Umansky, V., Sevko, A., Gebhardt, C. & Utikal, J., 11.2014, In: J DTSCH DERMATOL GES. 12, 11, p. 1021-7 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  52. Efficacy of vemurafenib in a trametinib-resistant stage IV melanoma patient--letter

    Bernhardt, M., Orouji, E., Larribere, L., Gebhardt, C. & Utikal, J., 01.05.2014, In: CLIN CANCER RES. 20, 9, p. 2498-9 2 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. 2010

  54. Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation

    Riehl, A., Bauer, T., Brors, B., Busch, H., Mark, R., Németh, J., Gebhardt, C., Bierhaus, A., Nawroth, P., Eils, R., König, R., Angel, P. & Hess, J., 05.10.2010, In: BMC GENOMICS. 11, p. 537

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  55. 2009

  56. S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis

    Németh, J., Stein, I., Haag, D., Riehl, A., Longerich, T., Horwitz, E., Breuhahn, K., Gebhardt, C., Schirmacher, P., Hahn, M., Ben-Neriah, Y., Pikarsky, E., Angel, P. & Hess, J., 10.2009, In: HEPATOLOGY. 50, 4, p. 1251-62 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  57. Standards and Trends in the Treatment of Malignant Melanoma

    Gebhardt, C. & Näher, H., 2009, In: Onkopipeline. 2, p. 101-113

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  58. 2008

  59. RAGE signaling sustains inflammation and promotes tumor development

    Gebhardt, C., Riehl, A., Durchdewald, M., Németh, J., Fürstenberger, G., Müller-Decker, K., Enk, A., Arnold, B., Bierhaus, A., Nawroth, P. P., Hess, J. & Angel, P., 18.02.2008, In: J EXP MED. 205, 2, p. 275-85 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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