Research ExplorerScientific StaffChristian Gorzelanny Publications

Dr.rer.nat. ID: 5308605

Christian Gorzelanny

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Affiliations
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Publications

  1. 2023

  2. Crosstalk between Circulating Tumor Cells and Plasma Proteins-Impact on Coagulation and Anticoagulation

    Wang, Y., Schneider, S. W. & Gorzelanny, C., 01.06.2023, In: CANCERS. 15, 11, 3025.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  3. Exostosin 1 Knockdown Induces Chemoresistance in MV3 Melanoma Cells by Upregulating JNK and MEK/ERK Signaling

    Pfeifer, V., Weber, H., Wang, Y., Schlesinger, M., Gorzelanny, C. & Bendas, G., 13.03.2023, In: INT J MOL SCI. 24, 6, 5452.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Cutaneous manifestations in Costello syndrome: HRAS p.Gly12Ser affects RIN1-mediated integrin trafficking in immortalized epidermal keratinocytes

    Nauth, T., Bazgir, F., Voß, H., Brandenstein, L. I., Mosaddeghzadeh, N., Rickassel, V., Deden, S., Gorzelanny, C., Schlüter, H., Ahmadian, M. R. & Rosenberger, G., 06.01.2023, In: HUM MOL GENET. 32, 2, p. 304-318 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. 2022

  6. Impact of neutrophil extracellular traps on fluid properties, blood flow and complement activation

    Burmeister, A., Vidal-Y-Sy, S., Liu, X., Mess, C., Wang, Y., Konwar, S., Tschongov, T., Häffner, K., Huck, V., Schneider, S. W. & Gorzelanny, C., 16.12.2022, In: FRONT IMMUNOL. 13, 1078891.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Key Role of Hyaluronan Metabolism for the Development of Brain Metastases in Triple-Negative Breast Cancer

    Hamester, F., Stürken, C., Legler, K., Eylmann, K., Möller, K., Roßberg, M., Gorzelanny, C., Bauer, A. T., Windhorst, S., Schmalfeldt, B., Laakmann, E., Müller, V., Witzel, I. & Oliveira-Ferrer, L., 18.10.2022, In: CELLS-BASEL. 11, 20, 3275.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Neutrophils activated by membrane attack complexes increase the permeability of melanoma blood vessels

    Liu, X., Wang, Y., Bauer, A. T., Kirschfink, M., Ding, P., Gebhardt, C., Borsig, L., Tüting, T., Renné, T., Häffner, K., Hu, W., Schneider, S. W. & Gorzelanny, C., 16.08.2022, In: P NATL ACAD SCI USA. 119, 33, e2122716119.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis

    Wang, Y., Liu, X., Obser, T., Bauer, A. T., Heyes, M., Starzonek, S., Zulal, M., Opitz, K., Ott, L., Riethdorf, S., Lange, T., Pantel, K., Bendas, G., Schneider, S. W., Kusche-Gullberg, M. & Gorzelanny, C., 08.2022, In: MATRIX BIOL. 111, p. 76-94 19 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Insights into the Steps of Breast Cancer-Brain Metastases Development: Tumor Cell Interactions with the Blood-Brain Barrier

    Hamester, F., Stürken, C., Saygi, C., Qi, M., Legler, K., Gorzelanny, C., Robador, J. R., Schmalfeldt, B., Laakmann, E., Müller, V., Witzel, I. & Oliveira-Ferrer, L., 08.02.2022, In: INT J MOL SCI. 23, 3, 1900.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Interplay between coagulation and inflammation in cancer: Limitations and therapeutic opportunities

    Bauer, A. T., Gorzelanny, C., Gebhardt, C., Pantel, K. & Schneider, S. W., 01.2022, In: CANCER TREAT REV. 102, 102322.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  12. 2021

  13. The Role of Interleukin-1-Receptor-Antagonist in Bladder Cancer Cell Migration and Invasion

    Schneider, L., Liu, J., Zhang, C., Azoitei, A., Meessen, S., Zheng, X., Cremer, C., Gorzelanny, C., Kempe-Gonzales, S., Brunner, C., Wezel, F., Bolenz, C., Gunes, C. & John, A., 30.05.2021, In: INT J MOL SCI. 22, 11, 5875.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Melanoma Associated Chitinase 3-Like 1 Promoted Endothelial Cell Activation and Immune Cell Recruitment

    Ramos-Espinosa, G., Wang, Y., Brandner, J. M., Schneider, S. W. & Gorzelanny, C., 10.04.2021, In: INT J MOL SCI. 22, 8, 3912.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Inhibition of Tumor-Host Cell Interactions Using Synthetic Heparin Mimetics

    Gockel, L. M., Heyes, M., Li, H., Al Nahain, A., Gorzelanny, C., Schlesinger, M., Holdenrieder, S., Li, J-P., Ferro, V. & Bendas, G., 17.02.2021, In: ACS APPL MATER INTER. 13, 6, p. 7080-7093 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Involvement of platelet-derived VWF in metastatic growth of melanoma in the brain

    Robador, J. R., Feinauer, M. J., Schneider, S. W., Mayer, F. T., Gorzelanny, C., Sacharow, A., Liu, X., Berghoff, A., Brehm, M. A., Hirsch, D., Stadler, J., Vidal-Y-Si, S., Wladykowski, E., Asong, M., Nowak, K., Seiz-Rosenhagen, M., Umansky, V., Mess, C., Pantel, K., Winkler, F. & Bauer, A. T., 2021, In: NEURO-ONCOL ADV. 3, 1, vdab175.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. 2020

  18. Differences of the tumour cell glycocalyx affect binding of capsaicin-loaded chitosan nanocapsules

    von Palubitzki, L., Wang, Y., Hoffmann, S., Vidal-Y-Sy, S., Zobiak, B., Failla, A. V., Schmage, P., John, A., Osorio-Madrazo, A., Bauer, A. T., Schneider, S. W., Goycoolea, F. M. & Gorzelanny, C., 31.12.2020, In: SCI REP-UK. 10, 1, p. 22443

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Bladder cancer-derived interleukin-1 converts the vascular endothelium into a pro-inflammatory and pro-coagulatory surface

    John, A., Günes, C., Bolenz, C., Vidal-Y-Sy, S., Bauer, A. T., Schneider, S. W. & Gorzelanny, C., 02.12.2020, In: BMC CANCER. 20, 1, p. 1178

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Nanoparticles and Colloidal Hydrogels of Chitosan-Caseinate Polyelectrolyte Complexes for Drug-Controlled Release Applications

    Lall, A., Kamdem Tamo, A., Doench, I., David, L., Nunes de Oliveira, P., Gorzelanny, C. & Osorio-Madrazo, A., 05.08.2020, In: INT J MOL SCI. 21, 16

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Skin Barriers in Dermal Drug Delivery: Which Barriers Have to Be Overcome and How Can We Measure Them?

    Gorzelanny, C., Mess, C., Schneider, S. W., Huck, V. & Brandner, J. M., 20.07.2020, In: PHARMACEUTICS. 12, 7

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  22. Urothelial Carcinoma of the Bladder Induces Endothelial Cell Activation and Hypercoagulation

    John, A., Robador, J. R., Vidal-Y-Sy, S., Houdek, P., Wladykowski, E., Günes, C., Bolenz, C., Schneider, S. W., Bauer, A. T. & Gorzelanny, C., 07.2020, In: MOL CANCER RES. 18, 7, p. 1099-1109 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Unique subsite specificity and potential natural function of a chitosan deacetylase from the human pathogen Cryptococcus neoformans

    Hembach, L., Bonin, M., Gorzelanny, C. & Moerschbacher, B. M., 18.02.2020, In: P NATL ACAD SCI USA. 117, 7, p. 3551-3559 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Claudin-1 decrease impacts epidermal barrier function in atopic dermatitis lesions dose-dependently

    Bergmann, S., von Buenau, B., Vidal-Y-Sy, S., Haftek, M., Wladykowski, E., Houdek, P., Lezius, S., Duplan, H., Bäsler, K., Dähnhardt-Pfeiffer, S., Gorzelanny, C., Schneider, S. W., Rodriguez, E., Stölzl, D., Weidinger, S. & Brandner, J. M., 06.02.2020, In: SCI REP-UK. 10, 1, p. 2024

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. 2019

  26. Smart antimicrobial efficacy employing pH-sensitive ZnO-doped diamond-like carbon coatings

    Buchegger, S., Kamenac, A., Fuchs, S., Herrmann, R., Houdek, P., Gorzelanny, C., Obermeier, A., Heller, S., Burgkart, R., Stritzker, B., Wixforth, A. & Westerhausen, C., 21.11.2019, In: SCI REP-UK. 9, 1, p. 17246

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. CCL2 is a vascular permeability factor inducing CCR2-dependent endothelial retraction during lung metastasis

    Roblek, M., Protsyuk, D., Becker, P. F., Stefanescu, C., Gorzelanny, C., Glaus Garzon, J. F., Knopfova, L., Heikenwalder, M., Luckow, B., Schneider, S. W. & Borsig, L., 03.2019, In: MOL CANCER RES. 17, 3, p. 783-793 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Cellulose Nanofiber-Reinforced Chitosan Hydrogel Composites for Intervertebral Disc Tissue Repair

    Doench, I., Ahn Tran, T., David, L., Montembault, A., Viguier, E., Gorzelanny, C., Sudre, G., Cachon, T., Louback-Mohamed, M., Horbelt, N., Peniche-Covas, C. & Osorio-Madrazo, A., 20.02.2019, In: BIOMIMETICS-BASEL. 4, 1

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Platelets in Skin Autoimmune Diseases

    Liu, X., Gorzelanny, C. & Schneider, S. W., 2019, In: FRONT IMMUNOL. 10, p. 1453

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  30. 2018

  31. The Influence of Capsaicin on the Integrity of Microvascular Endothelial Cell Monolayers

    Kaiser, M., Burek, M., Britz, S., Lankamp, F., Ketelhut, S., Kemper, B., Förster, C., Gorzelanny, C. & Goycoolea, F. M., 30.12.2018, In: INT J MOL SCI. 20, 1

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Physicochemical Characterization of FRET-Labelled Chitosan Nanocapsules and Model Degradation Studies

    Hoffmann, S., Gorzelanny, C., Moerschbacher, B. & Goycoolea, F. M., 17.10.2018, In: NANOMATERIALS-BASEL. 8, 10, p. 846

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. The endothelial glycocalyx anchors von Willebrand factor fibers to the vascular endothelium

    Kalagara, T., Moutsis, T., Yang, Y., Pappelbaum, K. I., Farken, A., Cladder-Micus, L., Vidal-Y-Sy, S., John, A., Bauer, A. T., Moerschbacher, B. M., Schneider, S. W. & Gorzelanny, C., 25.09.2018, In: Blood Adv. 2, 18, p. 2347-2357 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Tight Junction barriers in human hair follicles - role of claudin-1

    Zorn-Kruppa, M., Vidal-Y-Sy, S., Houdek, P., Wladykowski, E., Grzybowski, S., Gruber, R., Gorzelanny, C., Harcup, J., Schneider, S. W., Majumdar, A. & Brandner, J. M., 24.08.2018, In: SCI REP-UK. 8, p. 12800

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy

    Nicolay, J. P., Thorn, V., Daniel, C., Amann, K., Siraskar, B., Lang, F., Hillgruber, C., Goerge, T., Hoffmann, S., Gorzelanny, C., Huck, V., Mess, C., Obser, T., Schneppenheim, R., Fleming, I., Schneider, M. F. & Schneider, S. W., 19.07.2018, In: SCI REP-UK. 8, 1, p. 10945

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. Chitosan functionalized poly-epsilon-caprolactone electrospun fibers and 3D printed scaffolds as antibacterial materials for tissue engineering applications

    Tardajos, M. G., Cama, G., Dash, M., Misseeuw, L., Gheysens, T., Gorzelanny, C., Coenye, T. & Dubruel, P., 01.07.2018, In: CARBOHYD POLYM. 191, p. 127-135 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Decreased Invasion of Urothelial Carcinoma of the Bladder by Inhibition of Matrix-Metalloproteinase 7

    Bolenz, C., Knauf, D., John, A., Erben, P., Steidler, A., Schneider, S. W., Günes, C. & Gorzelanny, C., 20.01.2018, In: Bladder Cancer. 4, 1, p. 67-75 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Local NGF and GDNF levels modulate morphology and function of porcine DRG neurites, In Vitro

    Klusch, A., Gorzelanny, C., Reeh, P. W., Schmelz, M., Petersen, M. & Sauer, S. K., 2018, In: PLOS ONE. 13, 9, p. e0203215

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. 2017

  40. Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair

    Kumar, V., Fleming, T., Terjung, S., Gorzelanny, C., Gebhardt, C., Agrawal, R., Mall, M. A., Ranzinger, J., Zeier, M., Madhusudhan, T., Ranjan, S., Isermann, B., Liesz, A., Deshpande, D., Häring, H-U., Biswas, S. K., Reynolds, P. R., Hammes, H-P., Peperkok, R., Angel, P., Herzig, S. & Nawroth, P. P., 13.10.2017, In: NUCLEIC ACIDS RES. 45, 18, p. 10595-10613 19 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. From morphology to clinical pathophysiology: multiphoton fluorescence lifetime imaging at patients' bedside

    Meß, C., Zens, K., Gorzelanny, C., Metze, D., Luger, T. A., König, K., Schneider, S. & Huck, V., 2017, In: Proc. SPIE. 10069, p. 100691E-100691E

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Nanoencapsulated capsaicin changes migration behavior and morphology of madin darby canine kidney cell monolayers

    Kaiser, M., Pohl, L., Ketelhut, S., Kastl, L., Gorzelanny, C., Götte, M., Schnekenburger, J., Goycoolea, F. M. & Kemper, B., 2017, In: PLOS ONE. 12, 11, p. e0187497

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Role of the Coagulation System in Genitourinary Cancers: Review

    John, A., Gorzelanny, C., Bauer, A. T., Schneider, S. W. & Bolenz, C., 2017, In: CLIN GENITOURIN CANC.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  44. 2016

  45. The Effect of Capsaicin Derivatives on Tight-Junction Integrity and Permeability of Madin-Darby Canine Kidney Cells

    Kaiser, M., Chalapala, S., Gorzelanny, C., Perali, R. S. & Goycoolea, F. M., 02.2016, In: J PHARM SCI-US. 105, 2, p. 630-638 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. IL17A-Mediated Endothelial Breach Promotes Metastasis Formation

    Kulig, P., Burkhard, S., Mikita-Geoffroy, J., Croxford, A. L., Hövelmeyer, N., Gyülvészi, G., Gorzelanny, C., Waisman, A., Borsig, L. & Becher, B., 01.2016, In: CANCER IMMUNOL RES. 4, 1, p. 26-32 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. 2015

  48. Nuclear heparanase-1 activity suppresses melanoma progression via its DNA-binding affinity

    Yang, Y., Gorzelanny, C., Bauer, A. T., Halter, N., Komljenovic, D., Bäuerle, T., Borsig, L., Roblek, M. & Schneider, S. W., 19.11.2015, In: ONCOGENE. 34, 47, p. 5832-42 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. Chitosan encapsulation modulates the effect of capsaicin on the tight junctions of MDCK cells

    Kaiser, M., Pereira, S., Pohl, L., Ketelhut, S., Kemper, B., Gorzelanny, C., Galla, H-J., Moerschbacher, B. M. & Goycoolea, F. M., 13.05.2015, In: SCI REP-UK. 5, p. 10048

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. 2013

  51. Uptake kinetics and nanotoxicity of silica nanoparticles are cell type dependent

    Blechinger, J., Bauer, A. T., Torrano, A. A., Gorzelanny, C., Bräuchle, C. & Schneider, S. W., 09.12.2013, In: SMALL. 9, 23, p. 3970-80, 3906

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. Assessing the invasive potential of bladder cancer: development and validation of a new preclinical assay

    Bolenz, C., Gorzelanny, C., Knauf, D., Keil, T., Steidler, A., Halter, N., Martini, T. & Schneider, S. W., 05.2013, In: J UROLOGY. 189, 5, p. 1939-44 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. Coculture model of sensory neurites and keratinocytes to investigate functional interaction: chemical stimulation and atomic force microscope-transmitted mechanical stimulation combined with live-cell imaging

    Klusch, A., Ponce, L., Gorzelanny, C., Schäfer, I., Schneider, S. W., Ringkamp, M., Holloschi, A., Schmelz, M., Hafner, M. & Petersen, M., 05.2013, In: J INVEST DERMATOL. 133, 5, p. 1387-90 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  54. 2011

  55. Cytotoxicity of silica nanoparticles through exocytosis of von Willebrand factor and necrotic cell death in primary human endothelial cells

    Bauer, A. T., Strozyk, E. A., Gorzelanny, C., Westerhausen, C., Desch, A., Schneider, M. F. & Schneider, S. W., 11.2011, In: BIOMATERIALS. 32, 33, p. 8385-93 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  56. 2010

  57. Human macrophage activation triggered by chitotriosidase-mediated chitin and chitosan degradation

    Gorzelanny, C., Pöppelmann, B., Pappelbaum, K., Moerschbacher, B. M. & Schneider, S. W., 11.2010, In: BIOMATERIALS. 31, 33, p. 8556-63 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  58. 2007

  59. Specific interaction between chitosan and matrix metalloprotease 2 decreases the invasive activity of human melanoma cells

    Gorzelanny, C., Pöppelmann, B., Strozyk, E., Moerschbacher, B. M. & Schneider, S. W., 10.2007, In: BIOMACROMOLECULES. 8, 10, p. 3035-40 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  60. Shear-induced unfolding triggers adhesion of von Willebrand factor fibers

    Schneider, S. W., Nuschele, S., Wixforth, A., Gorzelanny, C., Alexander-Katz, A., Netz, R. R. & Schneider, M. F., 08.05.2007, In: P NATL ACAD SCI USA. 104, 19, p. 7899-903 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  61. 2006

  62. Atomic force microscopy as an innovative tool for nanoanalysis of native stratum corneum

    Gorzelanny, C., Goerge, T., Schnaeker, E-M., Thomas, K., Luger, T. A. & Schneider, S. W., 05.2006, In: EXP DERMATOL. 15, 5, p. 387-91 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review