Dr.med. ID: 44150
Chi-un Choe
Publications
- 2024
Dopaminergic mesolimbic structural reserve is positively linked to better outcome after severe stroke
Asmussen, L., Frey, B. M., Frontzkowski, L. K., Wróbel, P. P., Grigutsch, L. S., Choe, C-U., Bönstrup, M., Cheng, B., Thomalla, G., Quandt, F., Gerloff, C. & Schulz, R., 2024, In: BRAIN COMMUN. 6, 3, fcae122.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Combined Short-Pulse and Directional Deep Brain Stimulation of the Thalamic Ventral Intermediate Area for Essential Tremor
Hidding, U., Lezius, S., Schaper, M., Buhmann, C., Gerloff, C., Pötter-Nerger, M., Hamel, W., Moll, C. K. E. & Choe, C-U., 12.2023, In: NEUROMODULATION. 26, 8, p. 1680-1688 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disability and persistent motor deficits are linked to structural crossed cerebellar diaschisis in chronic stroke
Guder, S., Sadeghi, F., Zittel, S., Quandt, F., Choe, C-U., Bönstrup, M., Cheng, B., Thomalla, G., Gerloff, C. & Schulz, R., 11.2023, In: HUM BRAIN MAPP. 44, 16, p. 5336-5345 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Developmental dynamics of homoarginine, ADMA and SDMA plasma levels from birth to adolescence
Baach, F., Meyer, B., Oh, J., Lezius, S., Böger, R., Schwedhelm, E., Choe, C-U. & Neu, A., 10.2023, In: AMINO ACIDS. 55, 10, p. 1381-1388 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homoarginine Associates with Carotid Intima-Media Thickness and Atrial Fibrillation and Predicts Adverse Events after Stroke
Schwieren, L., Jensen, M., Schulz, R., Lezius, S., Laxy, E., Milatz, M., Thomalla, G., Böger, R., Gerloff, C., Magnus, T., Schwedhelm, E. & Choe, C-U., 20.07.2023, In: LIFE-BASEL. 13, 7, 1590.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Early functional connectivity alterations in contralesional motor networks influence outcome after severe stroke: a preliminary analysis
Braaß, H., Gutgesell, L., Backhaus, W., Higgen, F., Quandt, F., Choe, C., Gerloff, C. & Schulz, R., 07.07.2023, In: SCI REP-UK. 13, 1, p. 11010 11010.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Blood neurofilament light chain in Parkinson's disease
Buhmann, C., Magnus, T. & Choe, C-U., 06.2023, In: J NEURAL TRANSM. 130, 6, p. 755-762 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Altered microstructure of the contralesional ventral premotor cortex and motor output after stroke
Wróbel, P. P., Guder, S., Feldheim, J. F., Graterol Pérez, J. A., Frey, B. M., Choe, C-U., Bönstrup, M., Cheng, B., Rathi, Y., Pasternak, O., Thomalla, G., Gerloff, C., Shenton, M. E. & Schulz, R., 2023, In: BRAIN COMMUN. 5, 3, fcad160.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Cortical thickness of contralesional cortices positively relates to future outcome after severe stroke
Rojas Albert, A., Backhaus, W., Graterol Pérez, J. A., Braaβ, H., Schön, G., Choe, C-U., Feldheim, J., Bönstrup, M., Cheng, B., Thomalla, G., Gerloff, C. & Schulz, R., 08.12.2022, In: CEREB CORTEX. 32, 24, p. 5622-5627 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reference Interval for Serum L-Homoarginine Determined with Enzyme-Linked Immunosorbent Assay in the Population-Based Study of Health in Pomerania
Schwedhelm, E., Cordts, K., Moritz, E., Wesemann, R., Choe, C. U., Böger, R., Ittermann, T., Dörr, M., Friedrich, N. & Bahls, M., 29.10.2022, In: J APPL LAB MED. 7, 6, p. 1272-1282 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effective high-density lipoprotein cholesterol is associated with carotid intima-media thickness and vascular events after acute ischemic stroke
Schwedhelm, E., Tiedt, S., Lezius, S., Wölfer, T. A., Jensen, M., Schulz, R., Böger, R., Gerloff, C., Thomalla, G. & Choe, C-U., 09.2022, In: ATHEROSCLEROSIS. 357, p. 9-13 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Structural cerebellar reserve positively influences outcome after severe stroke
Sadeghihassanabadi, F., Frey, B. M., Backhaus, W., Choe, C-U., Zittel, S., Schön, G., Bönstrup, M., Cheng, B., Thomalla, G., Gerloff, C. & Schulz, R., 04.08.2022, In: BRAIN COMMUN. 4, 6, p. fcac203Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reply to: "Diabetes and Neuroaxonal Damage in Parkinson's Disease"
Buhmann, C., Pötter-Nerger, M., Schulz, R., Gerloff, C., Kuhle, J. & Choe, C-U., 07.2022, In: MOVEMENT DISORD. 37, 7, p. 1569-1570 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Diabetes, Glycated Hemoglobin (HbA1c), and Neuroaxonal Damage in Parkinson's Disease (MARK-PD Study)
Uyar, M., Lezius, S., Buhmann, C., Pötter-Nerger, M., Schulz, R., Meier, S., Gerloff, C., Kuhle, J. & Choe, C-U., 06.2022, In: MOVEMENT DISORD. 37, 6, p. 1299-1304 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Population kinetics of homoarginine and optimized supplementation for cardiovascular risk reduction
Kleist, C. J., Choe, C-U., Atzler, D., Schönhoff, M., Böger, R., Schwedhelm, E. & Wicha, S. G., 06.2022, In: AMINO ACIDS. 54, 6, p. 889-896 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Short pulse and directional thalamic deep brain stimulation have differential effects in parkinsonian and essential tremor
Hidding, U., Schaper, M., Gulberti, A., Buhmann, C., Gerloff, C., Moll, C. K. E., Hamel, W., Choe, C-U. & Pötter-Nerger, M., 04.05.2022, In: SCI REP-UK. 12, 1, 7251.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of Montreal cognitive assessment and Mattis dementia rating scale in the preoperative evaluation of subthalamic stimulation in Parkinson's disease
Gülke, E., Alsalem, M., Kirsten, M., Vettorazzi, E., Choe, C-U., Hidding, U., Zittel-Dirks, S., Buhmann, C., Schaper, M., Gulberti, A., Moll, C. K. E., Hamel, W., Koeppen, J., Gerloff, C. & Pötter-Nerger, M., 07.04.2022, In: PLOS ONE. 17, 4, e0265314.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of cardiovascular-related microRNAs is altered in L-arginine:glycine amidinotransferase deficient mice
Jensen, M., Müller, C., Hübner, N., Patone, G., Saar, K., Choe, C-U., Schwedhelm, E. & Zeller, T., 24.03.2022, In: SCI REP-UK. 12, 1, 5108.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Serum neurofilament light chain and postural instability/gait difficulty (PIGD) subtypes of Parkinson's disease in the MARK-PD study
Pötter-Nerger, M., Dutke, J., Lezius, S., Buhmann, C., Schulz, R., Gerloff, C., Kuhle, J. & Choe, C-U., 03.2022, In: J NEURAL TRANSM. 129, 3, p. 295-300 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Age-Adjusted Serum Neurofilament Predicts Cognitive Decline in Parkinson's Disease (MARK-PD)
Buhmann, C., Lezius, S., Pötter-Nerger, M., Gerloff, C., Kuhle, J. & Choe, C-U., 12.02.2022, In: MOVEMENT DISORD. 37, 2, p. 435-436 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Relationship Between Cortical Excitability Changes and Cortical Thickness in Subcortical Chronic Stroke
Graterol Pérez, J. A., Guder, S., Choe, C-U., Gerloff, C. & Schulz, R., 2022, In: FRONT NEUROL. 13, 802113.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Serum Sphingosine-1-Phosphate Levels Are Associated With Severity and Outcome in Patients With Cerebral Ischemia
Schwedhelm, E., Schwieren, L., Tiedt, S., von Lucadou, M., Gloyer, N-O., Böger, R., Magnus, T., Daum, G., Thomalla, G., Gerloff, C. & Choe, C-U., 12.2021, In: STROKE. 52, 12, p. 3901-3907 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Serum neurofilament is associated with motor function, cognitive decline and subclinical cardiac damage in advanced Parkinson's disease (MARK-PD)
Niemann, L., Lezius, S., Maceski, A., Leppert, D., Englisch, C., Schwedhelm, E., Zeller, T., Gerloff, C., Kuhle, J. & Choe, C-U., 09.2021, In: PARKINSONISM RELAT D. 90, p. 44-48 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sphingosine-1-Phosphate, Motor Severity, and Progression in Parkinson's Disease (MARK-PD)
Schwedhelm, E., Englisch, C., Niemann, L., Lezius, S., von Lucadou, M., Marmann, K., Böger, R., Peine, S., Daum, G., Gerloff, C. & Choe, C-U., 09.2021, In: MOVEMENT DISORD. 36, 9, p. 2178-2182 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HbA1c and Motor Outcome in Parkinson's Disease in the Mark-PD Study
Zittel, S., Uyar, M., Lezius, S., Gerloff, C. & Choe, C-U., 08.2021, In: MOVEMENT DISORD. 36, 8, p. 1991-1992 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Association of lipid levels with motor and cognitive function and decline in advanced Parkinson's disease in the Mark-PD study
Choe, C-U., Petersen, E., Lezius, S., Cheng, B., Schulz, R., Buhmann, C., Pötter-Nerger, M., Daum, G., Blankenberg, S., Gerloff, C., Schwedhelm, E. & Zeller, T., 04.2021, In: PARKINSONISM RELAT D. 85, p. 5-10 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Trimethyllysine, vascular risk factors and outcome in acute ischemic stroke (MARK-STROKE)
Schwedhelm, E., von Lucadou, M., Peine, S., Lezius, S., Thomalla, G., Böger, R., Gerloff, C. & Choe, C-U., 04.2021, In: AMINO ACIDS. 53, 4, p. 555-561 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reply to: "Parkin Deficiency Appears Not to Be Associated with Cardiac Damage in Parkinson's Disease"
Choe, C-U., Pötter-Nerger, M., Buhmann, C., Blankenberg, S., Gerloff, C., Schwedhelm, E. & Zeller, T., 01.2021, In: MOVEMENT DISORD. 36, 1, p. 273-274 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Arginine:Glycine Amidinotransferase Is Essential for Creatine Supply in Mice During Chronic Hypoxia
Hannemann, J., Cordts, K., Seniuk, A., Choe, C-U., Schmidt-Hutten, L., Duque Escobar, J., Weinberger, F., Böger, R. & Schwedhelm, E., 2021, In: FRONT PHYSIOL. 12, p. 703069Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Major central nervous system complications after allogeneic stem cell transplantation: a large retrospective study on 888 consecutive adult patients
Mannina, D., Berneking, L., Both, A., Timm, W., Urbanowicz, T., Wolschke, C., Ayuk, F. A., Fischer, N., Fiehler, J., Grzyska, U., Rösner, S., Choe, C-U., Kröger, N. & Christopeit, M., 12.2020, In: EUR J HAEMATOL. 105, 6, p. 722-730 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Subclinical Cardiac Microdamage, Motor Severity, and Cognition in Parkinson's Disease
Choe, C-U., Niemann, L., Englisch, C., Petersen, E., Buhmann, C., Pötter-Nerger, M., Blankenberg, S., Gerloff, C., Schwedhelm, E. & Zeller, T., 18.10.2020, In: MOVEMENT DISORD. 35, 10, p. 1863-1868 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reply to: "N-Terminal Pro-B-Type Natriuretic Peptide Levels in Parkinson's Disease"
Choe, C-U., Petersen, E., Pötter-Nerger, M., Buhmann, C., Blankenberg, S., Gerloff, C., Schwedhelm, E. & Zeller, T., 10.2020, In: MOVEMENT DISORD. 35, 10, p. 1888Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Creatine, guanidinoacetate and homoarginine in statin-induced myopathy
Neu, A., Hornig, S., Sasani, A., Isbrandt, D., Gerloff, C., Tsikas, D., Schwedhelm, E. & Choe, C-U., 07.2020, In: AMINO ACIDS. 52, 6-7, p. 1067-1069 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Analysis of L-arginine:glycine amidinotransferase-, creatine- and homoarginine-dependent gene regulation in the murine heart
Jensen, M., Müller, C., Choe, C-U., Schwedhelm, E. & Zeller, T., 16.03.2020, In: SCI REP-UK. 10, 1, 4821.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homoarginine- and Creatine-Dependent Gene Regulation in Murine Brains with l-Arginine:Glycine Amidinotransferase Deficiency
Jensen, M., Müller, C., Schwedhelm, E., Arunachalam, P., Gelderblom, M., Magnus, T., Gerloff, C., Zeller, T. & Choe, C-U., 09.03.2020, In: INT J MOL SCI. 21, 5, 1865.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Arginine Derivatives in Cerebrovascular Diseases: Mechanisms and Clinical Implications
Grosse, G. M., Schwedhelm, E., Worthmann, H. & Choe, C-U., 05.03.2020, In: INT J MOL SCI. 21, 5Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Low homoarginine/SDMA ratio is associated with poor short- and long-term outcome after stroke in two prospective studies
Choe, C-U., Lezius, S., Cordts, K., Gerloff, C., Böger, R. H., Schwedhelm, E. & Grant, P. J., 01.2020, In: NEUROL SCI. 41, 1, p. 149-153 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Muscle phenotype of AGAT- and GAMT-deficient mice after simvastatin exposure
Sasani, A., Hornig, S., Grzybowski, R., Cordts, K., Hanff, E., Tsikas, D., Böger, R., Gerloff, C., Isbrandt, D., Neu, A., Schwedhelm, E. & Choe, C-U., 01.2020, In: AMINO ACIDS. 52, 1, p. 73-85 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Evidence by GC-MS that lysine is an arginase-catalyzed metabolite of homoarginine in vitro and in vivo in humans
Bollenbach, A., Cordts, K., Hanff, E., Atzler, D., Choe, C-U., Schwedhelm, E. & Tsikas, D., 15.07.2019, In: ANAL BIOCHEM. 577, p. 59-66 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mapping stimulation-induced beneficial and adverse effects in the subthalamic area of essential tremor patients
Hidding, U., Schaper, M., Moll, C. K. E., Gulberti, A., Köppen, J., Buhmann, C., Gerloff, C., Pötter-Nerger, M., Hamel, W. & Choe, C-U., 07.2019, In: PARKINSONISM RELAT D. 64, p. 150-155 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the WAKE-UP Trial
Barow, E., Boutitie, F., Cheng, B., Cho, T-H., Ebinger, M., Endres, M., Fiebach, J. B., Fiehler, J., Ford, I., Galinovic, I., Nickel, A., Puig, J., Roy, P., Wouters, A., Magnus, T., Thijs, V., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Gerloff, C., Thomalla, G. & WAKE-UP Investigators, 01.06.2019, In: JAMA NEUROL. 76, 6, p. 641-649 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Modulation of specific components of sleep disturbances by simultaneous subthalamic and nigral stimulation in Parkinson's disease
Hidding, U., Gulberti, A., Pflug, C., Choe, C., Horn, A., Prilop, L., Braaß, H., Fründt, O., Buhmann, C., Weiss, D., Westphal, M., Engel, A. K., Gerloff, C., Köppen, J. A., Hamel, W., Moll, C. K. E. & Pötter-Nerger, M., 05.2019, In: PARKINSONISM RELAT D. 62, p. 141-147 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA(2)DS(2)-VASc score in three cross-sectional studies
Cordts, K., Grzybowski, R., Lezius, S., Lüneburg, N., Atzler, D., Neu, A., Hornig, S., Böger, R. H., Gerloff, C., Magnus, T., Thomalla, G., Schwedhelm, E., Grant, P. J. & Choe, C-U., 15.02.2019, In: J NEUROL SCI. 397, p. 156-161 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Thalamic short pulse stimulation diminishes adverse effects in essential tremor patients
Choe, C-U., Hidding, U., Schaper, M., Gulberti, A., Köppen, J., Buhmann, C., Gerloff, C., Moll, C. K. E., Hamel, W. & Pötter-Nerger, M., 21.08.2018, In: NEUROLOGY. 91, 8, p. e704-e713Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Towards unambiguous reporting of complications related to deep brain stimulation surgery: A retrospective single-center analysis and systematic review of the literature
Engel, K., Huckhagel, T., Gulberti, A., Pötter-Nerger, M., Vettorazzi, E., Hidding, U., Choe, C-U., Zittel, S., Braaß, H., Ludewig, P., Schaper, M., Krajewski, K., Oehlwein, C., Mittmann, K., Engel, A. K., Gerloff, C., Westphal, M., Moll, C. K. E., Buhmann, C., Köppen, J. A. & Hamel, W., 02.08.2018, In: PLOS ONE. 13, 8, p. e0198529Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure
Reichold, M., Klootwijk, E. D., Reinders, J., Otto, E. A., Milani, M., Broeker, C., Laing, C., Wiesner, J., Devi, S., Zhou, W., Schmitt, R., Tegtmeier, I., Sterner, C., Doellerer, H., Renner, K., Oefner, P. J., Dettmer, K., Simbuerger, J. M., Witzgall, R., Stanescu, H. C., Dumitriu, S., Iancu, D., Patel, V., Mozere, M., Tekman, M., Jaureguiberry, G., Issler, N., Kesselheim, A., Walsh, S. B., Gale, D. P., Howie, A. J., Martins, J. R., Hall, A. M., Kasgharian, M., O'Brien, K., Ferreira, C. R., Atwal, P. S., Jain, M., Hammers, A., Charles-Edwards, G., Choe, C-U., Isbrandt, D., Cebrian-Serrano, A., Davies, B., Sandford, R. N., Pugh, C., Konecki, D. S., Povey, S., Bockenhauer, D., Lichter-Konecki, U., Gahl, W. A., Unwin, R. J., Warth, R. & Kleta, R., 07.2018, In: J AM SOC NEPHROL. 29, 7, p. 1849-1858 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cognitive performance of 20 healthy humans supplemented with L-homoarginine for 4 weeks
Schönhoff, M., Weineck, G., Hoppe, J., Hornig, S., Cordts, K., Atzler, D., Gerloff, C., Böger, R., Neu, A., Schwedhelm, E. & Choe, C-U., 04.2018, In: J CLIN NEUROSCI. 50, p. 237-241 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
How does it feel to be operated on the brain? Perceived intraoperative stress of movement disorder patients undergoing awake deep brain stimulation surgery
Sieger, J., Gulberti, A., Köppen, J., Pinnschmidt, H., Nitzschke, R., Schaper, M., Braaß, H., Buhmann, C., Choe, C., Hidding, U., Zittel, S., Engel, A. K., Mehnert, A., Gerloff, C., Westphal, M., Pötter-Nerger, M., Hamel, W. & Moll, C., 16.03.2018, The many faces of Parkinson’s disease – Motor and non ‐ motor symptoms from prodromal to advanced disease stages.Research output: SCORING: Contribution to book/anthology › Conference contribution - Poster › Research
Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine
Faller, K. M. E., Atzler, D., McAndrew, D. J., Zervou, S., Whittington, H. J., Simon, J. N., Aksentijevic, D., Ten Hove, M., Choe, C-U., Isbrandt, D., Casadei, B., Schneider, J. E., Neubauer, S. & Lygate, C. A., 01.03.2018, In: CARDIOVASC RES. 114, 3, p. 417-430 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A Mouse Model of Creatine Transporter Deficiency Reveals Impaired Motor Function and Muscle Energy Metabolism
Stockebrand, M., Sasani, A., Das, D., Hornig, S., Hermans-Borgmeyer, I., Lake, H. A., Isbrandt, D., Lygate, C. A., Heerschap, A., Neu, A. & Choe, C-U., 2018, In: FRONT PHYSIOL. 9, p. 773Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review