Research ExplorerScientific StaffArne Hansen Publications

Prof. Dr. ID: 76616

Arne Hansen

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Publications

  1. 2017

  2. Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes

    Prondzynski, M., Krämer, E., Laufer, S., Domke-Shibamiya, A., Pless, O., Flenner, F., Müller, O. J., Münch, J., Redwood, C., Hansen, A., Patten-Hamel, M., Eschenhagen, T., Mearini, G. & Carrier, L., 05.2017, In: MOL THER-NUCL ACIDS. 7, p. 475-486

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Automated Contraction Analysis of Human Engineered Heart Tissue for Cardiac Drug Safety Screening

    Mannhardt, I., Saleem, U., Benzin, A., Schulze, T., Klampe, B., Eschenhagen, T. & Hansen, A., 15.04.2017, In: JOVE-J VIS EXP. 122, p. e55461

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Thymosin4 Improves Differentiation and Vascularization of EHTs

    Ziegler, T., Hinkel, R., Stöhr, A., Eschenhagen, T., Laugwitz, K-L., le Noble, F., David, R., Hansen, A. & Kupatt, C., 01.2017, In: Stem cells international. 2017, p. 6848271

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. 2016

  6. Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells

    Weinberger, F., Breckwoldt, K., Pecha, S., Kelly, A., Geertz, B., Starbatty, J., Yorgan, T., Cheng, K-H., Lessmann, K., Stolen, T., Scherrer-Crosbie, M., Smith, G., Reichenspurner, H., Hansen, A. & Eschenhagen, T., 02.11.2016, In: SCI TRANSL MED. 8, 363, p. 363ra148

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Human Engineered Heart Tissue: Analysis of Contractile Force

    Mannhardt, I., Breckwoldt, K., Letuffe-Brenière, D., Schaaf, S., Schulz, H., Neuber, C., Benzin, A., Werner, T., Eder, A., Schulze, T., Klampe, B., Christ, T., Hirt, M. N., Huebner, N., Moretti, A., Eschenhagen, T. & Hansen, A., 12.07.2016, In: STEM CELL REP. 7, 1, p. 29-42 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Spontaneous Formation of Extensive Vessel-Like Structures in Murine Engineered Heart Tissue

    Stoehr, A., Hirt, M. N., Hansen, A., Seiffert, M., Conradi, L., Uebeler, J., Limbourg, F. P. & Eschenhagen, T., 02.2016, In: TISSUE ENG PT A. 22, 3-4, p. 326-35 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Human engineered heart tissue as a model system for drug testing

    Eder, A., Vollert, I., Hansen, A. & Eschenhagen, T., 15.01.2016, In: ADV DRUG DELIVER REV. 96, p. 214-24 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue

    Jacob, F., Yonis, A. Y., Cuello, F., Luther, P., Schulze, T., Eder, A., Streichert, T., Mannhardt, I., Hirt, M. N., Schaaf, S., Stenzig, J., Force, T., Eschenhagen, T. & Hansen, A., 2016, In: PLOS ONE. 11, 2, p. e0145937

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions

    Uzun, A. U., Mannhardt, I., Breckwoldt, K., Horváth, A., Johannsen, S. S., Hansen, A., Eschenhagen, T. & Christ, T., 2016, In: FRONT PHARMACOL. 7, p. 300

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Towards a Tissue-Engineered Contractile Fontan-Conduit: The Fate of Cardiac Myocytes in the Subpulmonary Circulation

    Biermann, D., Eder, A., Arndt, F., Seoudy, H., Reichenspurner, H., Mir, T., Riso, A., Kozlik-Feldmann, R., Peldschus, K., Kaul, M. G., Schuler, T., Krasemann, S., Hansen, A., Eschenhagen, T. & Sachweh, J. S., 2016, In: PLOS ONE. 11, 11, p. e0166963

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. 2015

  14. Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization

    Fiedler, J., Breckwoldt, K., Remmele, C. W., Hartmann, D., Dittrich, M., Pfanne, A., Just, A., Xiao, K., Kunz, M., Müller, T., Hansen, A., Geffers, R., Dandekar, T., Eschenhagen, T. & Thum, T., 03.11.2015, In: J AM COLL CARDIOL. 66, 18, p. 2005-15 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Immunobiology of fibrin-based engineered heart tissue

    Conradi, L., Schmidt, S., Neofytou, E., Deuse, T., Peters, L., Eder, A., Hua, X., Hansen, A., Robbins, R. C., Beygui, R. E., Reichenspurner, H., Eschenhagen, T. & Schrepfer, S., 06.2015, In: STEM CELL TRANSL MED. 4, 6, p. 625-631 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Engineering Cardiovascular Regeneration

    Vollert, I., Eder, A., Hansen, A. & Eschenhagen, T., 03.04.2015, In: CURR STEM CELL REP. 1, 2, p. 67-78 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Deciphering the microRNA signature of pathological cardiac hypertrophy by engineered heart tissue- and sequencing-technology

    Hirt, M. N., Werner, T., Indenbirken, D., Alawi, M., Demin, P., Kunze, A-C., Stenzig, J., Starbatty, J., Hansen, A., Fiedler, J., Thum, T. & Eschenhagen, T., 01.04.2015, In: J MOL CELL CARDIOL. 81, p. 1-9 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Protection by the NO-Donor SNAP and BNP against Hypoxia/Reoxygenation in Rat Engineered Heart Tissue

    Görbe, A., Eder, A., Varga, Z. V., Pálóczi, J., Hansen, A., Ferdinandy, P. & Eschenhagen, T., 2015, In: PLOS ONE. 10, 7, p. e0132186

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. 2014

  20. Effects of proarrhythmic drugs on relaxation time and beating pattern in rat engineered heart tissue

    Eder, A., Hansen, A., Uebeler, J., Schulze, T., Neuber, C., Schaaf, S., Yuan, L., Christ, T., Vos, M. A. & Eschenhagen, T., 01.11.2014, In: BASIC RES CARDIOL. 109, 6, p. 436

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. P425Cytoprotection by the NO-donor SNAP and BNP against ischemia/reperfusion injury in rat engineered heart tissue

    Gorbe, A., Eder, A., Varga, Z., Paloczi, J., Hansen, A., Ferdinandy, P. & Eschenhagen, T., 15.07.2014, In: CARDIOVASC RES. 103 Suppl 1, p. S78

    Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. P635Proarrhythmic drugs exert hERG-independent slowing of relaxation and irregular beating in rat engineered heart tissue

    Eder, A., Hansen, A., Neuber, C., Schaaf, S., Vos, M. & Eschenhagen, T., 15.07.2014, In: CARDIOVASC RES. 103 Suppl 1, p. S115

    Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review

  23. P778Physiological and pharmacological characterization of human engineered heart tissue

    Vollert, I., Schaaf, S., Neuber, C., Letuffe-Breniere, D., Breckwoldt, K., Shibamiya, A., Stimpel, D., Eder, A., Eschenhagen, T. & Hansen, A., 15.07.2014, In: CARDIOVASC RES. 103 Suppl 1, p. S143

    Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review

  24. Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation

    Hirt, M. N., Boeddinghaus, J., Mitchell, A., Schaaf, S., Börnchen, C., Müller, C., Schulz, H., Hubner, N., Stenzig, J., Stoehr, A., Neuber, C., Eder, A., Luther, P. K., Hansen, A. & Eschenhagen, T., 19.05.2014, In: J MOL CELL CARDIOL. 74C, p. 151-161 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Automated analysis of contractile force and Ca2+ transients in engineered heart tissue

    Stoehr, A., Neuber, C., Baldauf, C., Vollert, I., Friedrich, F. W., Flenner, F., Carrier, L., Eder, A., Schaaf, S., Hirt, M. N., Aksehirlioglu, B., Tong, C. W., Moretti, A., Eschenhagen, T. & Hansen, A., 01.05.2014, In: AM J PHYSIOL-HEART C. 306, 9, p. H1353-H1363

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Hamburger Pharmakologie-Repetitorium: Eine Übersicht klinisch relevanter arzneitherapeutischer Fakten

    Wuttke, A. H., Eschenhagen, T., Hirt, M., Hansen, A., Stenzig, J., Weinberger, F., Werner, U., Friedrich, F., Schwedhelm, E., Lüneburg, N. & Anderssohn, M., 04.02.2014, Hamburger Pharmakologie-Repetitorium: Eine Übersicht klinisch relevanter arzneitherapeutischer Fakten. Wuttke, A. H. & Eschenhagen, T. (eds.). 3 ed. Hamburg: Eigenverlag, 197 p.

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Education

  27. In vitro perfusion of engineered heart tissue through endothelialized channels

    Vollert, I., Seiffert, M., Bachmair, J., Sander, M., Eder, A., Conradi, L., Vogelsang, A., Schulze, T., Uebeler, J., Holnthoner, W., Redl, H., Reichenspurner, H., Hansen, A. & Eschenhagen, T., 01.02.2014, In: TISSUE ENG PT A. 20, 3-4, p. 854-63 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Cardiac Tissue Engineering State of the Art

    Hirt, M. N., Hansen, A. & Eschenhagen, T., 17.01.2014, In: CIRC RES. 114, 2, p. 354-367 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Generation of Strip-Format Fibrin-Based Engineered Heart Tissue (EHT)

    Schaaf, S., Eder, A., Vollert, I., Stöhr, A., Hansen, A. & Eschenhagen, T., 2014, Cardiac Tissue Engineering: Methods and Protocols . Radisic, M. & Black III, L. D. (eds.). 1 ed. New York: Springer Science+Business Media New York, Vol. 1181. p. 121-129 9 p. (Methods in Molecular Biology ; vol. 1181).

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review

  30. 2013

  31. Functional MicroRNA Library Screening Identifies the HypoxaMiR MiR-24 as a Potent Regulator of Smooth Muscle Cell Proliferation and Vascularization

    Fiedler, J., Stöhr, A., Gupta, S. K., Hartmann, D., Holzmann, A., Just, A., Hansen, A., Hilfiker-Kleiner, D., Eschenhagen, T. & Thum, T., 19.11.2013, In: ANTIOXID REDOX SIGN.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome of ETV6-RUNX1 negative B precursor acute lymphoblastic leukemia

    Harder, L., Eschenburg, G., Zech, A., Kriebitzsch, N., Otto, B., Streichert, T., Behlich, A-S., Dierck, K., Klingler, B., Hansen, A., Stanulla, M., Zimmermann, M., Kremmer, E., Stocking, C. & Horstmann, M. A., 21.10.2013, In: J EXP MED. 210, 11, p. 2289-304 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice

    Stöhr, A., Friedrich, F. W., Flenner, F., Geertz, B., Eder, A., Schaaf, S., Hirt, M. N., Uebeler, J., Schlossarek, S., Carrier, L., Hansen, A. & Eschenhagen, T., 01.10.2013, In: J MOL CELL CARDIOL. 63, p. 189-98 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Heterozygous LmnadelK32 mice develop dilated cardiomyopathy through a combined pathomechanism of haploinsufficiency and peptide toxicity

    Cattin, M-E., Bertrand, A. T., Schlossarek, S., Le Bihan, M-C., Skov Jensen, S., Neuber, C., Crocini, C., Maron, S., Lainé, J., Mougenot, N., Varnous, S., Fromes, Y., Hansen, A., Eschenhagen, T., Decostre, V., Carrier, L. & Bonne, G., 01.08.2013, In: HUM MOL GENET. 22, 15, p. 3152-64 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Impact of ANKRD1 mutations associated with hypertrophic cardiomyopathy on contraction parameters of engineered heart tissue

    Crocini, C., Arimura, T., Reischmann, S., Eder, A., Braren, I., Hansen, A., Eschenhagen, T., Kimura, A. & Carrier, L., 01.01.2013, In: BASIC RES CARDIOL. 108, 3, p. 349

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. 2012

  37. Complex interactions between human myoblasts and the surrounding 3D fibrin-based matrix.

    Chiron, S., Tomczak, C., Duperray, A., Lainé, J., Bonne, G., Eder, A., Hansen, A., Eschenhagen, T., Verdier, C. & Coirault, C., 2012, In: PLOS ONE. 7, 4, p. 36173 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Evidence for FHL1 as a novel disease gene for isolated hypertrophic cardiomyopathy.

    Friedrich, F., Wilding, B. R., Reischmann, S., Crocini, C., Lang, P., Charron, P., Müller, O. J., McGrath, M. J., Vollert, I., Hansen, A., Linke, W. A., Hengstenberg, C., Bonne, G., Morner, S., Wichter, T., Madeira, H., Arbustini, E., Eschenhagen, T., Mitchell, C. A., Isnard, R. & Carrier, L., 2012, In: HUM MOL GENET. 21, 14, p. 3237-3254 14.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Increased afterload induces pathological cardiac hypertrophy: a new in vitro model.

    Hirt, M., Sörensen, N. A., Bartholdt, L. M., Boeddinghaus, J., Schaaf, S., Eder, A., Vollert, I., Stöhr, A., Schulze, T., Witten, A., Stoll, M., Hansen, A. & Eschenhagen, T., 2012, In: BASIC RES CARDIOL. 107, 6, p. 307 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Physiological aspects of cardiac tissue engineering.

    Eschenhagen, T., Eder, A., Vollert, I. & Hansen, A., 2012, In: AM J PHYSIOL-HEART C. 303, 2, p. 133-143 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Succinate reverses in-vitro platelet inhibition by acetylsalicylic acid and P2Y receptor antagonists.

    Spath, B., Hansen, A., Bokemeyer, C. & Langer, F., 2012, In: PLATELETS. 23, 1, p. 60-68 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. 2011

  43. Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology.

    Eschenhagen, T., Force, T., Ewer, M. S., Keulenaer, D., Gilles, W., Suter, T. M., Anker, S. D., Avkiran, M., de Azambuja, E., Balligand, J-L., Brutsaert, D. L., Hansen, A., Hansen, A., Heymans, S., Hill, J. A., Hirsch, E., Hilfiker-Kleiner, D., Janssens, S., de Jong, S., Neubauer, G., Pieske, B., Ponikowski, P., Pirmohamed, M., Rauchhaus, M., Sawyer, D., Sugden, P. H., Wojta, J., Zannad, F. & Shah, A. M., 01.01.2011, In: EUR J HEART FAIL. 13, 1, p. 1-10 10 p., 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Bioluminescence imaging for assessment of immune responses following implantation of engineered heart tissue (EHT).

    Conradi, L., Pahrmann, C., Schmidt, S., Deuse, T., Hansen, A., Eder, A., Reichenspurner, H., Robbins, R. C., Eschenhagen, T. & Schrepfer, S., 2011, In: JOVE-J VIS EXP. 52, p. 2605

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology.

    Schaaf, S., Shibamiya, A., Mewe, M., Eder, A., Stöhr, A., Hirt, M., Rau, T., Zimmermann, W-H., Conradi, L., Eschenhagen, T. & Hansen, A., 2011, In: PLOS ONE. 6, 10, p. 26397 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. 2010

  47. Sorafenib

    Hansen, A. & Eschenhagen, T., 01.09.2010, In: DEUT MED WOCHENSCHR. 135, 37, p. 1819-1822 4 p., 37.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Development of a drug screening platform based on engineered heart tissue.

    Hansen, A., Eder, A., Bönstrup, M., Flato, M., Mewe, M., Schaaf, S., Aksehirlioglu, B., Schwoerer, A., Uebeler, J. & Eschenhagen, T., 2010, In: CIRC RES. 107, 1, p. 35-44 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling.

    Martins, D. C., Paula, A., Salic, K., Gladka, M. M., Armand, A-S., Leptidis, S., Hansen, A., Hansen, A., Roo, C., Christina, J., Bierhuizen, M. F., van der Nagel, R., van Kuik, J., de Weger, R., de Bruin, A., Eschenhagen, T., Arbones, M. L., Eschenhagen, T., Windt, D. & Leon, J., 2010, In: NAT CELL BIOL. 12, 12, p. 1220-1227 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing.

    Will, R. D., Eden, M., Just, S., Hansen, A., Eder, A., Frank, D., Kuhn, C., Seeger, T. S., Oehl, U., Wiemann, S., Korn, B., Koegl, M., Rottbauer, W., Eschenhagen, T., Katus, H. A. & Frey, N., 2010, In: CIRC RES. 107, 10, p. 1253-1264 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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