Dr. ID: 5310294
Alexander Bauer
Publications
- 2023
Prognostic value of von Willebrand factor levels in patients with metastatic melanoma treated by immune checkpoint inhibitors
Stadler, J-C., Keller, L., Mess, C., Bauer, A. T., Koett, J., Geidel, G., Heidrich, I., Vidal-Y-Sy, S., Andreas, A., Stramaglia, C., Sementsov, M., Haberstroh, W., Deitert, B., Hoehne, I. L., Reschke, R., Haalck, T., Pantel, K., Gebhardt, C. & Schneider, S. W., 05.2023, In: J IMMUNOTHER CANCER. 11, 5, e006456.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization
Karreman, M. A., Bauer, A. T., Solecki, G., Berghoff, A. S., Mayer, C. D., Frey, K., Hebach, N., Feinauer, M. J., Schieber, N. L., Tehranian, C., Mercier, L., Singhal, M., Venkataramani, V., Schubert, M. C., Hinze, D., Hölzel, M., Helfrich, I., Schadendorf, D., Schneider, S. W., Westphal, D., Augustin, H. G., Goetz, J. G., Schwab, Y., Wick, W. & Winkler, F., 14.04.2023, In: CANCER RES. 83, 8, p. 1299-1314 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Von Willebrand factor in the plasma and in the tumor tissue predicts cancer-associated thrombosis and mortality
Karampinis, I., Nowak, K., Koett, J., Mess, C., Wagner, L., Gaiser, T., Mayer, F. T., Goertz, L., Schneider, S. W. & Bauer, A. T., 01.01.2023, In: HAEMATOLOGICA. 108, 1, p. 261-266 6 p.Research output: SCORING: Contribution to journal › Letter › Research
- 2022
Activated Eosinophils Predict Longer Progression-Free Survival under Immune Checkpoint Inhibition in Melanoma
Ammann, N. L., Schwietzer, Y. F., Mess, C., Stadler, J-C., Geidel, G., Kött, J., Pantel, K., Schneider, S. W., Utikal, J., Bauer, A. T. & Gebhardt, C., 18.11.2022, In: CANCERS. 14, 22, 5676.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunothrombotic Mechanisms Induced by Ingenol Mebutate Lead to Rapid Necrosis and Clearance of Anogenital Warts
Braun, S. A., Bauer, A. T., Németh, C., Rózsa, A., Rusch, L., Erpenbeck, L., Schloer, S., Silling, S., Metze, D., Gerber, P. A., Schneider, S. W., Gyulai, R. & Homey, B., 02.11.2022, In: INT J MOL SCI. 23, 21, 13377.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Key Role of Hyaluronan Metabolism for the Development of Brain Metastases in Triple-Negative Breast Cancer
Hamester, F., Stürken, C., Legler, K., Eylmann, K., Möller, K., Roßberg, M., Gorzelanny, C., Bauer, A. T., Windhorst, S., Schmalfeldt, B., Laakmann, E., Müller, V., Witzel, I. & Oliveira-Ferrer, L., 18.10.2022, In: CELLS-BASEL. 11, 20, 3275.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neutrophils activated by membrane attack complexes increase the permeability of melanoma blood vessels
Liu, X., Wang, Y., Bauer, A. T., Kirschfink, M., Ding, P., Gebhardt, C., Borsig, L., Tüting, T., Renné, T., Häffner, K., Hu, W., Schneider, S. W. & Gorzelanny, C., 16.08.2022, In: P NATL ACAD SCI USA. 119, 33, e2122716119.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis
Wang, Y., Liu, X., Obser, T., Bauer, A. T., Heyes, M., Starzonek, S., Zulal, M., Opitz, K., Ott, L., Riethdorf, S., Lange, T., Pantel, K., Bendas, G., Schneider, S. W., Kusche-Gullberg, M. & Gorzelanny, C., 08.2022, In: MATRIX BIOL. 111, p. 76-94 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tumor cell E-selectin ligands determine partialefficacy of bortezomib on spontaneous lung metastasis formation of solid human tumors in vivo
Lange, T., Valentiner, U., Wicklein, D., Maar, H., Labitzky, V., Ahlers, A-K., Starzonek, S., Genduso, S., Staffeldt, L., Pahlow, C., Dück, A-M., Stürken, C., Baranowsky, A., Bauer, A. T., Bulk, E., Schwab, A., Riecken, K., Börnchen, C., Kiefmann, R., Abraham, V., DeLisser, H. M., Gemoll, T., Habermann, J. K., Block, A., Pantel, K. & Schumacher, U., 06.04.2022, In: MOL THER. 30, 4, p. 1536-1552 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interplay between coagulation and inflammation in cancer: Limitations and therapeutic opportunities
Bauer, A. T., Gorzelanny, C., Gebhardt, C., Pantel, K. & Schneider, S. W., 01.2022, In: CANCER TREAT REV. 102, 102322.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2021
Local blood coagulation drives cancer cell arrest and brain metastasis in a mouse model
Feinauer, M. J., Schneider, S. W., Berghoff, A. S., Robador, J. R., Tehranian, C., Karreman, M. A., Venkataramani, V., Solecki, G., Grosch, J. K., Gunkel, K., Kovalchuk, B., Mayer, F. T., Fischer, M., Breckwoldt, M. O., Brune, M., Schwab, Y., Wick, W., Bauer, A. T. & Winkler, F., 04.03.2021, In: BLOOD. 137, 9, p. 1219-1232 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Platelet endothelial cell adhesion molecule-1 is a gatekeeper of neutrophil transendothelial migration in ischemic stroke
Winneberger, J., Schöls, S., Lessmann, K., Rández-Garbayo, J., Bauer, A. T., Mohamud Yusuf, A., Hermann, D. M., Gunzer, M., Schneider, S. W., Fiehler, J., Gerloff, C., Gelderblom, M., Ludewig, P. & Magnus, T., 03.2021, In: BRAIN BEHAV IMMUN. 93, p. 277-287 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Editorial: The Role of Platelets in Cancer Progression and Malignancy
Schlesinger, M., Gobec, M. & Bauer, A. T., 2021, In: FRONT ONCOL. 11, p. 814006Research output: SCORING: Contribution to journal › Editorial › Research
Involvement of platelet-derived VWF in metastatic growth of melanoma in the brain
Robador, J. R., Feinauer, M. J., Schneider, S. W., Mayer, F. T., Gorzelanny, C., Sacharow, A., Liu, X., Berghoff, A., Brehm, M. A., Hirsch, D., Stadler, J., Vidal-Y-Si, S., Wladykowski, E., Asong, M., Nowak, K., Seiz-Rosenhagen, M., Umansky, V., Mess, C., Pantel, K., Winkler, F. & Bauer, A. T., 2021, In: NEURO-ONCOL ADV. 3, 1, vdab175.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Differences of the tumour cell glycocalyx affect binding of capsaicin-loaded chitosan nanocapsules
von Palubitzki, L., Wang, Y., Hoffmann, S., Vidal-Y-Sy, S., Zobiak, B., Failla, A. V., Schmage, P., John, A., Osorio-Madrazo, A., Bauer, A. T., Schneider, S. W., Goycoolea, F. M. & Gorzelanny, C., 31.12.2020, In: SCI REP-UK. 10, 1, p. 22443Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bladder cancer-derived interleukin-1 converts the vascular endothelium into a pro-inflammatory and pro-coagulatory surface
John, A., Günes, C., Bolenz, C., Vidal-Y-Sy, S., Bauer, A. T., Schneider, S. W. & Gorzelanny, C., 02.12.2020, In: BMC CANCER. 20, 1, p. 1178Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ALCAM contributes to brain metastasis formation in non-small-cell lung cancer through interaction with the vascular endothelium
Münsterberg, J., Loreth, D., Brylka, L., Werner, S., Karbanova, J., Gandrass, M., Schneegans, S., Besler, K., Hamester, F., Robador, J. R., Bauer, A. T., Werner Schneider, S., Wrage, M., Lamszus, K., Matschke, J., Vashist, Y., Uzunoglu, G., Steurer, S., Horst, A. K., Oliveira-Ferrer, L., Glatzel, M., Schinke, T., Corbeil, D., Pantel, K., Maire, C. & Wikman, H., 07.07.2020, In: NEURO-ONCOLOGY. 22, 7, p. 955-966 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Urothelial Carcinoma of the Bladder Induces Endothelial Cell Activation and Hypercoagulation
John, A., Robador, J. R., Vidal-Y-Sy, S., Houdek, P., Wladykowski, E., Günes, C., Bolenz, C., Schneider, S. W., Bauer, A. T. & Gorzelanny, C., 07.2020, In: MOL CANCER RES. 18, 7, p. 1099-1109 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
The endothelial glycocalyx anchors von Willebrand factor fibers to the vascular endothelium
Kalagara, T., Moutsis, T., Yang, Y., Pappelbaum, K. I., Farken, A., Cladder-Micus, L., Vidal-Y-Sy, S., John, A., Bauer, A. T., Moerschbacher, B. M., Schneider, S. W. & Gorzelanny, C., 25.09.2018, In: Blood Adv. 2, 18, p. 2347-2357 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Role of the Coagulation System in Genitourinary Cancers: Review
John, A., Gorzelanny, C., Bauer, A. T., Schneider, S. W. & Bolenz, C., 2017, In: CLIN GENITOURIN CANC.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2016
Heparins that block VEGF-A-mediated von Willebrand factor fiber generation are potent inhibitors of hematogenous but not lymphatic metastasis
Goertz, L., Schneider, S. W., Desch, A., Mayer, F. T., Koett, J., Nowak, K., Karampinis, I., Bohlmann, M. K., Umansky, V. & Bauer, A. T., 18.10.2016, In: ONCOTARGET. 7, 42, p. 68527-68545 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Nuclear heparanase-1 activity suppresses melanoma progression via its DNA-binding affinity
Yang, Y., Gorzelanny, C., Bauer, A. T., Halter, N., Komljenovic, D., Bäuerle, T., Borsig, L., Roblek, M. & Schneider, S. W., 19.11.2015, In: ONCOGENE. 34, 47, p. 5832-42 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
von Willebrand factor fibers promote cancer-associated platelet aggregation in malignant melanoma of mice and humans
Bauer, A. T., Suckau, J., Frank, K., Desch, A., Goertz, L., Wagner, A. H., Hecker, M., Goerge, T., Umansky, L., Beckhove, P., Utikal, J., Gorzelanny, C., Diaz-Valdes, N., Umansky, V. & Schneider, S. W., 14.05.2015, In: BLOOD. 125, 20, p. 3153-63 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Desmoglein 2 depletion leads to increased migration and upregulation of the chemoattractant secretoneurin in melanoma cells
Peitsch, W. K., Doerflinger, Y., Fischer-Colbrie, R., Huck, V., Bauer, A. T., Utikal, J., Goerdt, S. & Schneider, S. W., 2014, In: PLOS ONE. 9, 2, p. e89491Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Uptake kinetics and nanotoxicity of silica nanoparticles are cell type dependent
Blechinger, J., Bauer, A. T., Torrano, A. A., Gorzelanny, C., Bräuchle, C. & Schneider, S. W., 09.12.2013, In: SMALL. 9, 23, p. 3970-80, 3906Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin alphavbeta5-induced secretion of VEGF-A
Desch, A., Strozyk, E. A., Bauer, A. T., Huck, V., Niemeyer, V., Wieland, T. & Schneider, S. W., 2012, In: AM J PATHOL. 181, 2, p. 693-705Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Cytotoxicity of silica nanoparticles through exocytosis of von Willebrand factor and necrotic cell death in primary human endothelial cells
Bauer, A. T., Strozyk, E. A., Gorzelanny, C., Westerhausen, C., Desch, A., Schneider, M. F. & Schneider, S. W., 11.2011, In: BIOMATERIALS. 32, 33, p. 8385-93 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Matrix metalloproteinase-9 mediates hypoxia-induced vascular leakage in the brain via tight junction rearrangement
Bauer, A. T., Bürgers, H. F., Rabie, T. & Marti, H. H., 04.2010, In: J CEREBR BLOOD F MET. 30, 4, p. 837-48 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review