Department of Pediatric Hematology and Oncology

Publications

  1. 1997
  2. Transcription of tal-1, a putative oncogene playing an important role in childhood T-ALL, can be shown in normal peripheral blood cells by a highly sensitive RT-PCR assay.

    Anderegg, B., Horstmann, M., Ernst, M. & Kabisch, H., 1997, In: PEDIATR HEMAT ONCOL. 14, 4, p. 349-358 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. 1996
  4. Prevalence of factor V Leiden in children with thrombo-embolism

    Aschka, I., Aumann, V., Bergmann, F., Budde, U., Eberl, W., Eckhof-Donovan, S., Krey, S., Nowak-Göttl, U., Schobess, R., Sutor, A. H., Wendisch, J. & Schneppenheim, R., 01.12.1996, In: EUR J PEDIATR. 155, 12, p. 1009-14 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Inherited defects of the protein C anticoagulant system in childhood thrombo-embolism

    Nowak-Göttl, U., Auberger, K., Göbel, U., Kreuz, W., Schneppenheim, R., Vielhaber, H., Zenz, W. & Zieger, B., 01.11.1996, In: EUR J PEDIATR. 155, 11, p. 921-7 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Results of a screening for von Willebrand disease type 2N in patients with suspected haemophilia A or von Willebrand disease type 1

    Schneppenheim, R., Budde, U., Krey, S., Drewke, E., Bergmann, F., Lechler, E., Oldenburg, J. & Schwaab, R., 01.10.1996, In: THROMB HAEMOSTASIS. 76, 4, p. 598-602 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Von Willebrand disease

    Schneppenheim, R., 09.1996, In: EUR J PEDIATR. 155, 9, p. 751-2 2 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Hepatopathie bei Patienten mit Neuroblastom Stadium 4S

    Claviez, A., Hero, B., Schneppenheim, R. & Berthold, F., 01.07.1996, In: KLIN PADIATR. 208, 4, p. 221-8 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Geographic distribution and origin of CFTR mutations in Germany

    Tümmler, B., Storrs, T., Dziadek, V., Dörk, T., Meitinger, T., Golla, A., Bertele-Harms, R. M., Harms, H. K., Schröder, E., Claass, A., Rutjes, J., Schneppenheim, R., Bauer, I., Breuel, K., Stuhrmann, M., Schmidtke, J., Lindner, M., Eigel, A., Horst, J., Kaiser, R., Lentze, M. J., Schmidt, K., von der Hardt, H. & Estivill, X., 01.06.1996, In: HUM GENET. 97, 6, p. 727-31 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Defective dimerization of von Willebrand factor subunits due to a Cys-> Arg mutation in type IID von Willebrand disease

    Schneppenheim, R., Brassard, J., Krey, S., Budde, U., Kunicki, T. J., Holmberg, L., Ware, J. & Ruggeri, Z. M., 16.04.1996, In: P NATL ACAD SCI USA. 93, 8, p. 3581-6 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. APC resistance in neonates and infants: adjustment of the APTT-based method

    Nowak-Göttl, U., Kohlhase, B., Vielhaber, H., Aschka, I., Schneppenheim, R. & Jürgens, H., 15.03.1996, In: THROMB RES. 81, 6, p. 665-70 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Resistance to activated protein C (APCR) in children with venous or arterial thromboembolism

    Nowak-Göttl, U., Koch, H. G., Aschka, I., Kohlhase, B., Vielhaber, H., Kurlemann, G., Oleszcuk-Raschke, K., Kehl, H. G., Jürgens, H. & Schneppenheim, R., 03.1996, In: BRIT J HAEMATOL. 92, 4, p. 992-8 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Comparison of the diagnostic and prognostic value of biological markers in neuroblastoma. Proposal for a common methodology of analysis. SENSE group.

    Favrot, M. C., Ambros, P., Schilling, F., Frappaz, D., Combaret, V., Berthold, F., Dominici, C., Erttmann, R., Esteve, J., Jenkner, A., Kerbl, R., Mann, J., Mathieu, P., Parker, L., Powell, J. & Philip, T., 1996, In: ANN ONCOL. 7, 6, p. 607-611 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Early toxicity of intensified conditioning with etoposide combined with total body irradiation/cyclophosphamide or busulfan/cyclophosphamide in children undergoing autologous or allogeneic bone marrow transplantation.

    Horstmann, M., Kroschke, G., Stockschläder, M., Betker, R., Krüger, W., Erttmann, R., Kabisch, H. & Zander, A., 1996, In: PEDIATR HEMAT ONCOL. 13, 1, p. 45-53 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Fatal outcome of disseminated candidosis after allogeneic bone marrow transplantation under treatment with liposomal and conventional amphotericin-B. A report of 4 cases with determination of the Mic values.

    Krüger, W., Sobottka, I., Stockschläder, M., Mross, K., Hoffknecht, M., Rüssmann, B., Horstmann, M., Betker, R. & Zander, A., 1996, In: SCAND J INFECT DIS. 28, 3, p. 313-316 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Growth arrest of solid human neuroblastoma xenografts in nude rats by natural IgM from healthy humans.

    David, K., Ollert, M. W., Juhl, H., Vollmert, C., Erttmann, R., Vogel, C. W. & Bredehorst, R., 1996, In: NAT MED. 2, 6, p. 686-689 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Hemophagocytic lymphohistiocytosis. Report of 122 children from the International Registry. FHL Study Group of the Histiocyte Society.

    Aricò, M., Janka, G., Fischer, A., Henter, J. I., Blanche, S., Janka-Schaub, G., Martinetti, M. & Rusca, M. P., 1996, In: LEUKEMIA. 10, 2, p. 197-203 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Impact of scheduling on toxicity and clinical efficacy of doxorubicin: what do we know in the mid-nineties?

    Bielack, S. S., Erttmann, R., Kempf-Bielack, B. & Winkler, K., 1996, In: EUR J CANCER. 32, 10, p. 1652-1660 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL). A prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM-90 and CoALL-05-92.

    Schlieben, S., Borkhardt, A., Reinisch, I., Ritterbach, J., Janssen, J. W., Ratei, R., Schrappe, M., Repp, R., Zimmermann, M., Kabisch, H., Janka-Schaub, G., Bartram, C. R., Ludwig, W. D., Riehm, H., Lampert, F. & Harbott, J., 1996, In: LEUKEMIA. 10, 6, p. 957-963 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. [Induction of multiple melanocytic nevus cell nevi in 2 children with malignant hematologic systemic diseases and chemotherapy-induced immunosuppression]

    Jappe, U., Abeck, D., Janka-Schaub, G., Gross, G., Jakob, T. & Ring, J., 1996, In: HAUTARZT. 47, 7, p. 537-540 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. MLL/ENL fusion in congenital acute lymphoblastic leukemia with a unique t(11;18;19).

    Horstmann, M., Argyriou-Tirita, A., Borkhardt, A., Kabisch, H., Kapaun, P., Winkler, K. & Haas, O. A., 1996, In: CANCER GENET-NY. 88, 2, p. 103-109 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Naturally occurring humoral cytotoxicity against neuroblastoma (NB) cells in healthy persons and NB patients.

    Erttmann, R., Schmitt, C., Ollert, M. W., David, K., Bredehorst, R. & Vogel, C. W., 1996, In: PEDIATR HEMAT ONCOL. 13, 6, p. 545-548 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Normal human serum contains a natural IgM antibody cytotoxic for human neuroblastoma cells.

    Ollert, M. W., David, K., Schmitt, C., Hauenschild, A., Bredehorst, R., Erttmann, R. & Vogel, C. W., 1996, In: P NATL ACAD SCI USA. 93, 9, p. 4498-4503 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Peripheral blast counts at diagnosis of late isolated bone marrow relapse of childhood acute lymphoblastic leukemia predict response to salvage chemotherapy and outcome. Berlin-Frankfurt-Münster Relapse Study Group.

    Bührer, C., Hartmann, R., Fengler, R., Rath, B., Schrappe, M., Janka-Schaub, G. & Henze, G., 1996, In: J CLIN ONCOL. 14, 10, p. 2812-2817 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Pharmacokinetics of the 5HT3 receptor antagonist tropisetron in children.

    Gaedicke, G., Erttmann, R., Henze, G., Hartmann, W., Drechsler, S., Grass, P., Faerber, L. & Kutz, K., 1996, In: PEDIATR HEMAT ONCOL. 13, 5, p. 405-416 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Randomized comparison of rotational chemotherapy in high-risk acute lymphoblastic leukaemia of childhood--follow up after 9 years. Coall Study Group.

    Janka-Schaub, G., Harms, D., Goebel, U., Graubner, U., Gutjahr, P., Haas, R. J., Juergens, H., Spaar, H. J. & Winkler, K., 1996, In: EUR J PEDIATR. 155, 8, p. 640-648 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. The recurrence patterns of stages I, II and III neuroblastoma: experience with 77 relapsing patients.

    Berthold, F., Hero, B., Breu, H., Christiansen, H., Erttmann, R., Gnekow, A., Herrmann, F., Klingebiel, T., Lampert, F., Müller-Weihrich, S. & Weinel, P., 1996, In: ANN ONCOL. 7, 2, p. 183-187 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Use of cryopreserved bone marrow in unrelated allogeneic transplantation.

    Stockschläder, M., Krüger, W., Tom Dieck, A., Horstmann, M., Altnöder, M., Löliger, C., Fiedler, W., Hoffknecht, M., Erttmann, R. & Zander, A., 1996, In: BONE MARROW TRANSPL. 17, 2, p. 197-199 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. 1995
  30. First case of disseminated Mycobacterium avium infection following chemotherapy for childhood acute myeloid leukemia

    Claass, A., Claviez, A., Westphal, E., Rüsch-Gerdes, S. & Schneppenheim, R., 01.09.1995, In: INFECTION. 23, 5, p. 301-2 2 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Cyclophosphamide/antithymocyte globulin conditioning of patients with severe aplastic anemia for marrow transplantation from HLA-matched siblings: preliminary results.

    Horstmann, M., Stockschläder, M., Krüger, W., Hoffknecht, M., Betker, R., Kabisch, H. & Zander, A., 01.08.1995, In: ANN HEMATOL. 71, 2, p. 77-81 5 p., 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Identification of a candidate missense mutation in a family with von Willebrand disease type IIC

    Schneppenheim, R., Thomas, K. B., Krey, S., Budde, U., Jessat, U., Sutor, A. H. & Zieger, B., 01.06.1995, In: HUM GENET. 95, 6, p. 681-6 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Cyclophosphamide/antithymocyte globulin conditioning of patients with severe aplastic anemia transplanted with bone marrow from HLA-identical related donors

    Horstmann, M., Stockschläder, M., Kabisch, H. & Zander, A., 01.03.1995, In: BLOOD. 85, 5, p. 1404-5 2 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Von Willebrand disease in childhood

    Schneppenheim, R., Thomas, K. B. & Sutor, A. H., 01.01.1995, In: SEMIN THROMB HEMOST. 21, 3, p. 261-75 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Complete resection before development of drug resistance is essential for survival from advanced hepatoblastoma--a report from the German Cooperative Pediatric Liver Tumor Study HB-89.

    von Schweinitz, D., Hecker, H., Harms, D., Bode, U., Weinel, P., Bürger, D., Erttmann, R. & Mildenberger, H., 1995, In: J PEDIATR SURG. 30, 6, p. 845-852 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Experience with liposomal Amphotericin-B in 60 patients undergoing high-dose therapy and bone marrow or peripheral blood stem cell transplantation.

    Krüger, W., Stockschläder, M., Rüssmann, B., Berger, C., Hoffknecht, M., Sobottka, I., Kohlschütter, B., Kroschke, G., Kröger, N. & Horstmann, M., 1995, In: BRIT J HAEMATOL. 91, 3, p. 684-690 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. [Intraspinal metastasis of stage I anaplastic Wilms tumor]

    Wiegel, T., Grzyska, U., Schwarz, R. & Escherich, G., 1995, In: STRAHLENTHER ONKOL. 171, 5, p. 296-299 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Liver iron stores in patients with secondary haemosiderosis under iron chelation therapy with deferoxamine or deferiprone.

    Nielsen, P., Fischer, R., Engelhardt, R., Tondüry, P., Gabbe, E. E. & Janka-Schaub, G., 1995, In: BRIT J HAEMATOL. 91, 4, p. 827-833 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Structurally modified anthracyclines retain activity in a cell line with simultaneous typical and atypical multidrug resistance.

    Bielack, S. S., Kallenbach, K., Looft, G., Erttmann, R. & Winkler, K., 1995, In: ANTICANCER RES. 15, 4, p. 1279-1284 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. 1994
  41. Genetic heterogeneity of severe von Willebrand disease type III in the German population

    Schneppenheim, R., Krey, S., Bergmann, F., Bock, D., Budde, U., Lange, M., Linde, R., Mittler, U., Meili, E. & Mertes, G., 01.12.1994, In: HUM GENET. 94, 6, p. 640-52 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. The impact of EBV, proliferation rate, and Bcl-2 expression in Hodgkin's disease in childhood

    Claviez, A., Tiemann, M., Peters, J., Kreipe, H., Schneppenheim, R. & Parwaresch, R., 01.02.1994, In: ANN HEMATOL. 68, 2, p. 61-6 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Malignant histiocytosis and large cell anaplastic (Ki-1) lymphoma in childhood: guidelines for differential diagnosis--report of the Histiocyte Society.

    Bucsky, P., Favara, B., Feller, A. C., Nezelof, C., Radzun, H. J., Schlegelberger, B. & Janka-Schaub, G., 1994, In: Med Pediatr Oncol. 22, 3, p. 200-203 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Relapse of MALT lymphoma associated with Helicobacter pylori after antibiotic treatment.

    Horstmann, M., Erttmann, R. & Winkler, K., 1994, In: LANCET. 343, 8905, p. 1098-1099 8905.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. [Results of the HB-89 Study in treatment of malignant epithelial liver tumors in childhood and concept of a new HB-94 protocol]

    von Schweinitz, D., Bürger, D., Bode, U., Weinel, P., Erttmann, R., Hecker, H. & Mildenberger, H., 1994, In: KLIN PADIATR. 206, 4, p. 282-288 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Screening for neuroblastoma.

    Schilling, F. H., Erttmann, R., Ambros, P. F., Strehl, S., Christiansen, H., Kovar, H., Kabisch, H. & Treuner, J., 1994, In: LANCET. 344, 8930, p. 1157-1158 8930.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. 1993
  48. von Willebrand factor mutation enhancing interaction with platelets in patients with normal multimeric structure

    Holmberg, L., Dent, J. A., Schneppenheim, R., Budde, U., Ware, J. & Ruggeri, Z. M., 01.05.1993, In: J CLIN INVEST. 91, 5, p. 2169-77 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. [BEP/VIP in children and adolescents with malignant non-testicular germ cell tumors. A comparison of the results of treatment of therapy studies MAKEI 83/86 and 89P/89]

    Göbel, U., Calaminus, G., Teske, C., Bamberg, M., Bökkerink, J. P., Haas, R. J., Holschneider, A. M., Janka-Schaub, G., Jürgens, H. & Mittler, U., 1993, In: KLIN PADIATR. 205, 4, p. 231-240 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Extracellular purine nucleosides elevated in chronic recidiving central nervous injury by deranged metabolism in phenylketonuria.

    Clemens, P. C., Prankel, B., Halfman, E., Erb, N. & Müller-Wickop, J., 1993, In: MED HYPOTHESES. 41, 3, p. 287-288 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Intraarterial chemotherapy for osteosarcoma: does the result really justify the effort?

    Bielack, S. S., Bieling, P., Erttmann, R. & Winkler, K., 1993, In: Cancer Treat Res. 62, p. 85-92

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. Phenylalanine, other large neutral amino acids and RNA catabolites as markers for protein biosynthesis in phenylketonuria.

    Clemens, P. C., Burmester, J. G., Wiegand, G., Prankel, B. H., Halfmann, E., Erb, N. & Müller-Wickop, J., 1993, In: METABOLISM. 42, 4, p. 531-532 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. Reversal of multidrug resistance in Friend leukemia cells by dexniguldipine-HCl.

    Reymann, A., Looft, G., Woermann, C., Dietel, M. & Erttmann, R., 1993, In: CANCER CHEMOTH PHARM. 32, 1, p. 25-30 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  54. 1992
  55. [Early neuroblastoma detection in Germany. On the status of the Hamburg-Stuttgart cooperative pilot study]

    Schilling, F. H., Erttmann, R., Dohrmann, S., Erb, N., Winkler, K., Gross, U. & Treuner, J., 1992, In: KLIN PADIATR. 204, 4, p. 282-287 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  56. [Effect of dose intensity and therapy-induced leukocytopenia in intensive therapy on the prognosis of acute lymphatic leukemia in childhood. Results in 213 patients of the COALL-85 study]

    Gobrecht, O., Göbel, U., Graubner, U., Gutjahr, P., Schöck, V., Spaar, H. J. & Janka-Schaub, G., 1992, In: KLIN PADIATR. 204, 4, p. 230-235 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review