Institute of Anatomy and Experimental Morphology
Publications
Refractory central nervous system vasculitis and gastrocnemius myalgia syndrome in Crohn's disease successfully treated with anti-tumor necrosis factor-alpha antibody.
Ullrich, S., Schinke, S., Both, M., Knop, K. C., Kirkiles-Smith, N. C., Gross, W. L. & Lamprecht, P., 2009, In: SEMIN ARTHRITIS RHEU. 38, 5, p. 337-347 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Severe impaired respiratory ciliary function in Wegener granulomatosis.
Ullrich, S., Gustke, H., Lamprecht, P., Gross, W. L., Schumacher, U., Ambrosch, P. & Laudien, M., 2009, In: ANN RHEUM DIS. 68, 6, p. 1067-1071 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Paul Ehrlich (1854-1915) and the Birth of Molecular Medicine
Valent, P., Sörgel, F., Schumacher, U., Groner, B. & Horny, H-P., 2015, In: The Hematologist. 12, 6, p. 1,6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine
Valent, P., Groner, B., Schumacher, U., Superti-Furga, G., Busslinger, M., Kralovics, R., Zielinski, C., Penninger, J. M., Kerjaschki, D., Stingl, G., Smolen, J. S., Valenta, R., Lassmann, H., Kovar, H., Jäger, U., Kornek, G., Müller, M. & Sörgel, F., 2016, In: J INNATE IMMUN. 8, 2, p. 111-20Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Redistribution, Homing and Organ-Invasion of Neoplastic Stem Cells in Myeloid Neoplasms
Valent, P., Sadovnik, I., Eisenwort, G., Herrmann, H., Bauer, K., Mueller, N., Sperr, W. R., Wicklein, D. & Schumacher, U., 02.2020, In: SEMIN CANCER BIOL. 60, p. 191-201 11 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Effects of bortezomib on human neuroblastoma cells in vitro and in a metastatic xenograft model.
Valentiner, U., Haane, C., Nehmann, N. & Schumacher, U., 2009, In: ANTICANCER RES. 29, 4, p. 1219-1225 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In vivo xenograft models of breast cancer metastasis.
Valentiner, U., Brooks, S. A. & Schumacher, U., 2006, In: Methods Mol Med. 120, p. 479-488Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of CD44 is associated with a metastatic pattern of human neuroblastoma cells in a SCID mouse xenograft model.
Valentiner, U., Valentiner, F-U. & Schumacher, U., 2008, In: TUMOR BIOL. 29, 3, p. 152-160 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[18F]FDG and [18F]FLT PET-CT and MR imaging of human neuroblastomas in a SCID mouse xenograft model.
Valentiner, U., Haane, C., Peldschus, K., Gustke, H., Brenner, W., Wilke, F., Pommert, A., Owsijewitsch, M., Schumacher, U. & Klutmann, S., 2008, In: ANTICANCER RES. 28, 5, p. 2561-2568 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of the neural cell adhesion molecule and polysialic acid in human neuroblastoma cell lines.
Valentiner, U., Mühlenhoff, M., Lehmann, U., Hildebrandt, H. & Schumacher, U., 2011, In: INT J ONCOL. 39, 2, p. 417-424 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ligands for the peroxisome proliferator-activated receptor-gamma have inhibitory effects on growth of human neuroblastoma cells in vitro.
Valentiner, U., Carlsson, M., Erttmann, R., Hildebrandt, H. & Schumacher, U., 2005, In: TOXICOLOGY. 213, 1-2, p. 157-168 1-2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HPA binding and metastasis formation of human breast cancer cell lines transplanted into severe combined immunodeficient (scid) mice
Valentiner, U., Hall, D. M. S., Brooks, S. A. & Schumacher, U., 10.03.2005, In: CANCER LETT. 219, 2, p. 233-42 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The influence of dietary lectins on the cell proliferation of human breast cancer cell lines in vitro
Valentiner, U., Fabian, S., Schumacher, U. & Leathem, A. J., 25.06.2003, In: ANTICANCER RES. 23, 2B, p. 1197-206 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selectin Binding Sites Are Involved in Cell Adhesive Properties of Head and Neck Squamous Cell Carcinoma
Valentiner, U., Knips, J., Pries, R., Clauditz, T., Münscher, A., Sauter, G., Wollenberg, B. & Schumacher, U., 28.10.2019, In: CANCERS. 11, 11Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Copy number gain at 8q12.1-q22.1 is associated with a malignant tumor phenotype in salivary gland myoepitheliomas.
Vékony, H., Röser, K., Löning, T., Ylstra, B., Meijer, G. A., Wieringen, V., Wessel, N., Wiel, V. D., Mark, A., Carvalho, B., Kok, K., Leemans, C. R., van der Waal, I. & Bloemena, E., 2009, In: GENE CHROMOSOME CANC. 48, 2, p. 202-212 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deregulated expression of p16INK4a and p53 pathway members in benign and malignant myoepithelial tumours of the salivary glands.
Vékony, H., Röser, K., Löning, T., Raaphorst, F. M., Leemans, C. R., Van der Waal, I. & Bloemena, E., 2008, In: HISTOPATHOLOGY. 53, 6, p. 658-666 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Performance of cone-beam computed tomography and multidetector computed tomography in diagnostic imaging of the midface: A comparative study on Phantom and cadaver head scans
Veldhoen, S., Schöllchen, M., Hanken, H., Precht, C., Henes, F. O., Schön, G., Nagel, H. D., Schumacher, U., Heiland, M., Adam, G. & Regier, M., 02.2017, In: EUR RADIOL. 27, 2, p. 790-800Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia
Velthaus, A., Cornils, K., Hennigs, J. K., Grüb, S., Stamm, H., Wicklein, D., Bokemeyer, C., Heuser, M., Windhorst, S., Fiedler, W. & Wellbrock, J., 26.10.2019, In: CANCERS. 11, 11Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Induction of apoptosis by mistletoe lectin I and its subunits. No evidence for cytotoxic effects caused by isolated A- and B-chains.
Vervecken, W., Kleff, S., Pfüller, U. & Büssing, A., 2000, In: INT J BIOCHEM CELL B. 32, 3, p. 317-326 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Successful treatment of Pseudomonas aeruginosa respiratory tract infection with a sugar solution--a case report on a lectin based therapeutic principle
von Bismarck, P., Schneppenheim, R. & Schumacher, U., 03.10.2001, In: KLIN PADIATR. 213, 5, p. 285-7 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene expression patterns and tumor uptake of 18F-FDG, 18F-FLT, and 18F-FEC in PET/MRI of an orthotopic mouse xenotransplantation model of pancreatic cancer.
von Forstner, C., Egberts, J-H., Ammerpohl, O., Niedzielska, D., Buchert, R., Mikecz, P., Schumacher, U., Peldschus, K., Adam, G., Pilarsky, C., Grutzmann, R., Kalthoff, H., Henze, E. & Brenner, W., 2008, In: J NUCL MED. 49, 8, p. 1362-1370 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Umbilical endometriosis.
von Stemm, A. M., Meigel, W. N., Scheidel, P. & Gocht, A., 1999, In: J EUR ACAD DERMATOL. 12, 1, p. 30-32 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Morphogenesis of the different types of photoreceptors of the chicken (Gallus domesticus) retina and the effect of amblyopia in neonatal chicken.
Wai, M. S. M., Lorke, D., Kung, L. S. & Yew, D. T. W., 2006, In: MICROSC RES TECHNIQ. 69, 2, p. 99-107 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The pattern of c-fos activation in the CNS is related to behavior in the mudskipper, Periophthalmus cantonensis.
Wai, M. S. M., Lorke, D., Webb, S. E. & Yew, D. T., 2006, In: BEHAV BRAIN RES. 167, 2, p. 318-327 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis
Wang, Y., Liu, X., Obser, T., Bauer, A. T., Heyes, M., Starzonek, S., Zulal, M., Opitz, K., Ott, L., Riethdorf, S., Lange, T., Pantel, K., Bendas, G., Schneider, S. W., Kusche-Gullberg, M. & Gorzelanny, C., 08.2022, In: MATRIX BIOL. 111, p. 76-94 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Computer simulation of the metastatic progression
Wedemann, G., Bethge, A., Haustein, V. & Schumacher, U., 01.01.2014, In: Methods Mol Biol. 1070, p. 107-16 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tumorigenic WAP-T mouse mammary carcinoma cells: a model for a self-reproducing homeostatic cancer cell system.
Wegwitz, F., Kluth, M-A., Mänz, C., Otto, B., Gruner, K., Heinlein, C., Kühl, M., Warnecke, G., Schumacher, U., Deppert, W. & Tolstonog, G. V., 2010, In: PLOS ONE. 5, 8, p. 12103 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ovarian cancer cells regulate their mitochondrial content and high mitochondrial content is associated with a poor prognosis
Weigelt, J., Petrosyan, M., Oliveira-Ferrer, L., Schmalfeldt, B., Bartmann, C., Dietl, J., Stürken, C. & Schumacher, U., 08.01.2024, In: BMC CANCER. 24, 1, p. 43Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of the distribution and structure of myocardium in the pulmonary veins for radiofrequency ablation of atrial fibrillation.
Weiss, C., Gocht, A., Willems, S., Hoffmann, M., Risius, T. & Meinertz, T., 2002, In: PACE. 25, 9, p. 1352-1356 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer
Werner, S., Frey, S., Riethdorf, S., Schulze, C., Alawi, M., Kling, L., Vafaizadeh, V., Sauter, G., Terracciano, L., Schumacher, U., Pantel, K. & Assmann, V., 09.08.2013, In: J BIOL CHEM. 288, 32, p. 22993-3008 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In contrast to specific B cells, human basophils are unaffected by the toxic activity of an allergen toxin due to lack of internalization of immunoglobulin E-bound allergen.
Wicklein, D., Stöcker, M., Klockenbring, T., Huhn, M., Wodrich, M., Haas, H., Becker, W-M., Barth, S. & Petersen, A., 2006, In: CLIN EXP ALLERGY. 36, 4, p. 531-542 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RNAi technology to block the expression of molecules relevant to metastasis: the cell adhesion molecule CEACAM1 as an instructive example.
Wicklein, D., 2012, In: Methods Mol Biol. 878, p. 241-250Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nilotinib and imatinib are comparably effective in reducing growth of human eosinophil leukemia cells in a newly established xenograft model.
Wicklein, D., Ramos Leal, N., Salamon, J. M., Thamer, M., Herrmann, H., Valent, P., Schumacher, U. & Ullrich, S., 2012, In: PLOS ONE. 7, 2, p. 30567 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
E- and p-selectins are essential for repopulation of chronic myelogenous and chronic eosinophilic leukemias in a scid mouse xenograft model
Wicklein, D., Schmidt, A., Labitzky, V., Ullrich, S., Valent, P. & Schumacher, U., 01.01.2013, In: PLOS ONE. 8, 7, p. e70139Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CEACAM1 promotes melanoma metastasis and is involved in the regulation of the EMT associated gene network in melanoma cells
Wicklein, D., Otto, B., Suling, A., Elies, E., Lüers, G., Lange, T., Feldhaus, S., Maar, H., Schröder-Schwarz, J., Brunner, G., Wagener, C. & Schumacher, U., 08.08.2018, In: SCI REP-UK. 8, p. 11893Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Early growth response proteins EGR-4 and EGR-3 interact with immune inflammatory mediators NF-kappaB p50 and p65.
Wieland, G. D., Nehmann, N., Müller, D., Eibel, H., Siebenlist, U., Sühnel, J., Zipfel, P. F. & Skerka, C., 2005, In: J CELL SCI. 118, 14, p. 3203-3212 14.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional role of inositol-1,4,5-trisphosphate-3-kinase-A for motility of malignant transformed cells.
Windhorst, S., Kalinina, T., Schmid, K., Blechner, C., Kriebitzsch, N., Hinsch, R., Chang, L., Herich, L., Schumacher, U. & Mayr, G. W., 2011, In: INT J CANCER. 129, 6, p. 1300-1309 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inositol-1,4,5-trisphosphate-3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumour cells by two functional activities.
Windhorst, S., Fliegert, R., Blechner, C., Möllmann, K., Hosseini, Z., Guenther, T., Eiben, M., Chang, L., Lin, H., Fanick, W., Schumacher, U., Brandt, B. & Mayr, G. W., 2010, In: J BIOL CHEM. 285, 8, p. 5541-5554 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of activated leukocyte cell adhesion molecule in the serum of breast cancer patients and implications for prognosis.
Witzel, I., Schröder, C., Müller, V., Zander, H., Tachezy, M., Henningsen, M., Jänicke, F. & Milde-Langosch, K., 2012, In: ONCOLOGY-BASEL. 82, 6, p. 305-312 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of HYAL1 expression in primary breast cancer in the formation of brain metastases
Witzel, I., Marx, A. K., Müller, V., Wikman, H., Matschke, J., Schumacher, U., Stürken, C., Prehm, P., Laakmann, E., Schmalfeldt, B., Milde-Langosch, K. & Oliveira-Ferrer, L., 04.2017, In: BREAST CANCER RES TR. 162, 3, p. 427-438 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Individualized early goal-directed therapy in systemic Inflammation: is full utilization of preload reserve the optimal strategy?
Wodack, K. H., Poppe, A. M., Tomkötter, L., Bachmann, K. A., Strobel, C. M., Bonk, S., Havel, J., Heckel, K., Gocht, A., Saugel, B., Mann, O., Izbicki, J. R., Goetz, A. E., Trepte, C. J. C. & Reuter, D. A., 01.12.2014, In: CRIT CARE MED. 42, 12, p. e741-51Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Enzyme and immunohistochemistry on undecalcified bone and bone marrow biopsies after embedding in plastic: a new embedding method for routine application
Wolf, E., Röser, K., Hahn, M., Welkerling, H. & Delling, G., 1992, In: Virchows Arch A Pathol Anat Histopathol. 420, 1, p. 17-24 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression and Functional Activity of the Human Bitter Taste Receptor TAS2R38 in Human Placental Tissues and JEG-3 Cells
Wölfle, U., Elsholz, F. A., Kersten, A., Haarhaus, B., Schumacher, U. & Schempp, C. M., 03.2016, In: MOLECULES. 21, 3, p. E306Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lectin Histochemistry for Metastasizing and Non-metastasizing Cancer Cells
Wolters-Eisfeld, G. & Schumacher, U., 2017, In: Methods Mol Biol. 1560, p. 121-132 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of the coxsackie adenovirus receptor in neuroendocrine lung cancers and its implications for oncolytic adenoviral infection.
Wunder, T., Schmid, K., Wicklein, D., Groitl, P., Dobner, T., Lange, T., Anders, M. & Schumacher, U., 2013, In: CANCER GENE THER. 20, 1, p. 25-32 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Coxsackie adenovirus receptor expression in carcinomas of the head and neck
Wunder, T., Schumacher, U. & Friedrich, R. E., 01.03.2012, In: ANTICANCER RES. 32, 3, p. 1057-62 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cre-mediated stress affects sirtuin expression levels, peroxisome biogenesis and metabolism, antioxidant and proinflammatory signaling pathways.
Xiao, Y., Karnati, S., Qian, G., Nenicu, A., Fan, W., Tchatalbachev, S., Höland, A., Hossain, H., Guillou, F., Lüers, G. & Baumgart-Vogt, E., 2012, In: PLOS ONE. 7, 7, p. 41097 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The microenvironment in the human lung partly determines the site of the first metastasis
Yanar, M., Abel, F., Haalck, T., Klutmann, S. & Schumacher, U., 01.07.2014, In: ANTICANCER RES. 34, 7, p. 3845-9 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selenium deficiency and fulvic acid supplementation induces fibrosis of cartilage and disturbs subchondral ossification in knee joints of mice: an animal model study of Kashin-Beck disease
Yang, C., Wolf, E., Röser, K., Delling, G. & Müller, P. K., 1993, In: Virchows Arch A Pathol Anat Histopathol. 423, 6, p. 483-91 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells
Zecher, B. F., Ellinghaus, D., Schloer, S., Niehrs, A., Padoan, B., Baumdick, M. E., Yuki, Y., Martin, M. P., Glow, D., Schröder-Schwarz, J., Niersch, J., Brias, S., Müller, L. M., Habermann, R., Kretschmer, P., Früh, T., Dänekas, J., Wehmeyer, M. H., Poch, T., Sebode, M., International PSC Study Group (IPSCSG), Ellinghaus, E., Degenhardt, F., Körner, C., Hoelzemer, A., Fehse, B., Oldhafer, K. J., Schumacher, U., Sauter, G., Carrington, M., Franke, A., Bunders, M. J., Schramm, C. & Altfeld, M., 05.01.2024, In: GUT. 73, 2, p. 325-337 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review