Institute of Pathology
Publications
- 2003
FosB is highly expressed in normal mammary epithelia, but down-regulated in poorly differentiated breast carcinomas.
Milde-Langosch, K., Kappes, H., Riethdorf, S., Löning, T. & Bamberger, A-M., 2003, In: BREAST CANCER RES TR. 77, 3, p. 265-275 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HER-2 and TOP2A coamplification in urinary bladder cancer.
Simon, R., Atefy, R., Wagner, U., Forster, T., Fijan, A., Bruderer, J., Wilber, K., Mihatsch, M. J., Gasser, T. & Sauter, G., 2003, In: INT J CANCER. 107, 5, p. 764-772 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High-throughput tissue microarray analysis of 11q13 gene amplification (CCND1, FGF3, FGF4, EMS1) in urinary bladder cancer.
Zaharieva, B. M., Simon, R., Diener, P-A., Ackermann, D., Maurer, R., Alund, G., Knönagel, H., Rist, M., Wilber, K., Hering, F., Schönenberger, A., Flury, R., Jäger, P., Fehr, J. L., Mihatsch, M. J., Gasser, T., Sauter, G. & Toncheva, D. I., 2003, In: J PATHOL. 201, 4, p. 603-608 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Methylation-specific PCR for DNA-based detection of occult tumor cells in lymph nodes of prostate cancer patients.
Köllermann, J., Müller, M., Goessl, C., Krause, H., Helpap, B., Pantel, K. & Miller, K., 2003, In: EUR UROL. 44, 5, p. 533-538 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
New hepatitis B virus of cranes that has an unexpected broad host range.
Prassolov, A., Hohenberg, H., Kalinina, T., Schneider, C., Cova, L., Krone, O., Frölich, K., Will, H. & Sirma, H., 2003, In: J VIROL. 77, 3, p. 1964-1976 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Oral lichen planus in patients with chronic liver diseases.
Friedrich, R. E., Heiland, M., El-Moawen, A., Dogan, A., von Schrenck, T. & Löning, T., 2003, In: INFECTION. 31, 6, p. 383-386 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains.
Möller, A., Sirma, H., Hofmann, T. G., Rueffer, S., Klimczak, E., Dröge, W., Will, H. & Schmitz, M. L., 2003, In: CANCER RES. 63, 15, p. 4310-4314 15.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative assessment of HER-2/neu protein concentration in breast cancer by enzyme-linked immunosorbent assay.
Müller, V., Thomssen, C., Karakas, C., Eustermann, I., Ramirez Porras, J., Coith, C., Berger, J., Löning, T., Jänicke, F. & Pantel, K., 2003, In: INT J BIOL MARKER. 18, 1, p. 13-20 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sequence analysis and high-throughput immunohistochemical profiling of KIT (CD 117) expression in uveal melanoma using tissue microarrays.
Pache, M., Glatz, K., Bösch, D., Dirnhofer, S., Mirlacher, M., Simon, R., Schraml, P., Rufle, A., Flammer, J., Sauter, G. & Meyer, P., 2003, In: VIRCHOWS ARCH. 443, 6, p. 741-744 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression.
Möller, A., Sirma, H., Hofmann, T. G., Staege, H., Gresko, E., Schmid, L. K., Klimczak, E., Dröge, W., Will, H. & Schmitz, M. L., 2003, In: ONCOGENE. 22, 54, p. 8731-8737 54.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tissue microarrays in cancer diagnosis.
Simon, R., Mirlacher, M. & Sauter, G., 2003, In: EXPERT REV MOL DIAGN. 3, 4, p. 421-430 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tissue microarrays in drug discovery.
Sauter, G., Simon, R. & Hillan, K., 2003, In: NAT REV DRUG DISCOV. 2, 12, p. 962-972 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tissue microarray (TMA) applications: implications for molecular medicine.
Simon, R. & Sauter, G., 2003, In: EXPERT REV MOL MED. 5, 26, p. 1-12 26.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Translocations t(11;18)(q21;q21) and t(14;18)(q32;q21) are the main chromosomal abnormalities involving MLT/MALT1 in MALT lymphomas.
Murga-Penas, E-M., Hinz, K., Röser, K., Copie-Bergman, C., Wlodarska, I., Marynen, P., Hagemeijer, A., Gaulard, P., Löning, T., Hossfeld, D. K. & Dierlamm, J., 2003, In: LEUKEMIA. 17, 11, p. 2225-2229 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2002
Amplification pattern of 12q13-q15 genes (MDM2, CDK4, GLI) in urinary bladder cancer.
Simon, R., Struckmann, K., Schraml, P., Wagner, U., Forster, T., Moch, H., Fijan, A., Bruderer, J., Wilber, K., Mihatsch, M. J., Gasser, T. & Sauter, G., 2002, In: ONCOGENE. 21, 16, p. 2476-2483 16.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Analysis of the progression of fibroepithelial tumours of the breast by PCR-based clonality assay.
Kuijper, A., Buerger, H., Simon, R., Schaefer, K-L., Croonen, A., Boecker, W., van der Wall, E., Diest, V. & Paul, J., 2002, In: J PATHOL. 197, 5, p. 575-581 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of the adhesion molecule CEACAM1 (CD66a, BGP, C-CAM) in breast cancer is associated with the expression of the tumor-suppressor genes Rb, Rb2, and p27.
Bamberger, A-M., Kappes, H., Methner, C., Rieck, G., Brümmer, J., Wagener, C., Löning, T. & Milde-Langosch, K., 2002, In: VIRCHOWS ARCH. 440, 2, p. 139-144 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[HER-2 and TOP2A gene amplification in urinary bladder cancer]
Simon, R., Atefy, R., Wagner, U., Forster, T., Fijan, A., Bruderer, J., Wilber, K., Mihatsch, M., Gasser T, G. & Sauter, G., 2002, In: Verh Dtsch Ges Pathol. 86, p. 176-183Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[HER-2 and TOP 2A gene amplifications in urinary bladder carcinoma]
Simon, R., Atefy, R., Wagner, U., Forster, T., Fijan, A., Bruderer, J., Wilber, K., Mihatsch, M. J., Gasser, T. & Sauter, G., 2002, In: Verh Dtsch Ges Pathol. 86, p. 176-183Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Heterogeneous proliferative potential of occult metastatic cells in bone marrow of patients with solid epithelial tumors.
Solakoglu, O., Maierhofer, C., Lahr, G., Breit, E., Scheunemann, P., Heumos, I., Pichlmeier, U., Schlimok, G., Oberneder, R., Kollermann, M. W., Köllermann, J., Speicher, M. R. & Pantel, K., 2002, In: P NATL ACAD SCI USA. 99, 4, p. 2246-2251 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human papillomaviruses, expression of p16, and early endocervical glandular neoplasia.
Riethdorf, L., Riethdorf, S., Lee, K. R., Cviko, A., Löning, T. & Crum, C. P., 2002, In: HUM PATHOL. 33, 9, p. 899-904 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Molecular genetics of urinary bladder cancer progression]
Sauter, G., Simon, R., Bubendorf, L. & Mihatsch, M., 2002, In: Verh Dtsch Ges Pathol. 86, p. 49-56Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Patterns of chromosomal aberrations in urinary bladder tumours and adjacent urothelium.
Steidl, C., Simon, R., Bürger, H., Brinkschmidt, C., Hertle, L., Böcker, W. & Terpe, H-J., 2002, In: J PATHOL. 198, 1, p. 115-120 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Predictive molecular pathology.
Sauter, G. & Simon, R., 2002, In: NEW ENGL J MED. 347, 25, p. 1995-1996 25.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prognostic relevance of MAGE-A4 tumor antigen expression in transitional cell carcinoma of the urinary bladder: a tissue microarray study.
Kocher, T., Zheng, M., Bolli, M., Simon, R., Forster, T., Schultz-Thater, E., Remmel, E., Noppen, C., Schmid, U., Ackermann, D., Mihatsch, M. J., Gasser, T., Heberer, M., Sauter, G. & Spagnoli, G. C., 2002, In: INT J CANCER. 100, 6, p. 702-705 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2.
Hofmann, T. G., Möller, A., Sirma, H., Zentgraf, H., Taya, Y., Dröge, W., Will, H. & Schmitz, M. L., 2002, In: NAT CELL BIOL. 4, 1, p. 1-10 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relative paucity of gross genetic alterations in myoepitheliomas and myoepithelial carcinomas of salivary glands.
Hungermann, D., Roeser, K., Buerger, H., Jäkel, T., Löning, T. & Herbst, H., 2002, In: J PATHOL. 198, 4, p. 487-494 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tissue microarrays for miniaturized high-throughput molecular profiling of tumors.
Simon, R. & Sauter, G., 2002, In: EXP HEMATOL. 30, 12, p. 1365-1372 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2001
Phänotyp-Genotyp-Korrelationen in Speicheldrüsentumoren - Stellenwert der molekularen Analytik -
Röser, K. & Löning, T., 11.2001, In: LARYNGO RHINO OTOL. 80, 11, p. 639-41 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pilotstudie zur prognostischen Wertigkeit der Her-2 Genamplifikation und Proliferationsaktivität beim Speichelgangkarzinom der grossen Kopfspeicheldrüsen1
Jaehne, M., Jäkel, K. T., Röser, K., Ussmüller, J. & Löning, T., 09.2001, In: LARYNGO RHINO OTOL. 80, 9, p. 525-529 5 p., 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of Rb2/p130 in breast and endometrial cancer: correlations with hormone receptor status.
Milde-Langosch, K., Goemann, C., Methner, C., Rieck, G., Bamberger, A. M. & Löning, T., 17.08.2001, In: BRIT J CANCER. 85, 4, p. 546-551 6 p., 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
p53-Mutationsnachweis in Abstrichen der Mundschleimhaut von Patienten mit oralem Plattenepithelkarzinom
Giese, M., Friedrich, R. E., Riethdorf, S. & Löning, T., 01.01.2001, In: Mund Kiefer Gesichtschir. 5, 1, p. 37-43 7 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Alterations of INK4a(p16-p14ARF)/INK4b(p15) expression and telomerase activation in meningioma progression.
Simon, M., Park, T. W., Köster, G., Mahlberg, R., Hackenbroch, M., Boström, J., Löning, T. & Schramm, J., 2001, In: J NEURO-ONCOL. 55, 3, p. 149-158 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A unique exonic splicing mutation in the human androgen receptor gene indicates a physiologic relevance of regular androgen receptor transcript variants.
Hellwinkel, O., Holterhus, P. M., Struve, D., Marschke, C., Homburg, N. & Hiort, O., 2001, In: J CLIN ENDOCR METAB. 86, 6, p. 2569-2575 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparative genomic hybridization in pineal parenchymal tumors.
Rickert, C. H., Simon, R., Bergmann, M., Dockhorn-Dworniczak, B. & Paulus, W., 2001, In: GENE CHROMOSOME CANC. 30, 1, p. 99-104 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cytogenetic analysis of multifocal bladder cancer supports a monoclonal origin and intraepithelial spread of tumor cells.
Simon, R., Eltze, E., Schäfer, K. L., Bürger, H., Semjonow, A., Hertle, L., Dockhorn-Dworniczak, B., Terpe, H. J. & Böcker, W., 2001, In: CANCER RES. 61, 1, p. 355-362 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distal chromosome 17 gains in neuroblastomas detected by comparative genomic hybridization (CGH) are associated with a poor clinical outcome.
Brinkschmidt, C., Christiansen, H., Terpe, H. J., Simon, R., Lampert, F., Boecker, W. & Dockhorn-Dworniczak, B., 2001, In: Med Pediatr Oncol. 36, 1, p. 11-13 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ductal invasive G2 and G3 carcinomas of the breast are the end stages of at least two different lines of genetic evolution.
Buerger, H., Mommers, E. C., Littmann, R., Simon, R., Diallo, R., Poremba, C., Dockhorn-Dworniczak, B., van Diest, P. J. & Boecker, W., 2001, In: J PATHOL. 194, 2, p. 165-170 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of cell-cycle regulatory proteins in endometrial carcinomas: correlations with hormone receptor status and clinicopathologic parameters.
Milde-Langosch, K., Bamberger, A. M., Goemann, C., Rössing, E., Rieck, G., Kelp, B. & Löning, T., 2001, In: J CANCER RES CLIN. 127, 9, p. 537-544 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of cyclin-dependent kinase inhibitors p16MTS1, p21WAF1, and p27KIP1 in HPV-positive and HPV-negative cervical adenocarcinomas.
Milde-Langosch, K., Riethdorf, S., Kraus-Pöppinghaus, A., Riethdorf, L. & Löning, T., 2001, In: VIRCHOWS ARCH. 439, 1, p. 55-61 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of vascular endothelial growth factor (VEGF) and VEGF receptor Flk-1 in benign, premalignant, and malignant prostate tissue.
Köllermann, J. & Helpap, B., 2001, In: AM J CLIN PATHOL. 116, 1, p. 115-121 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression pattern of the adhesion molecule CEACAM1 (C-CAM, CD66a, BGP) in gestational trophoblastic lesions.
Bamberger, A. M., Sudahl, S., Wagener, C. & Löning, T., 2001, In: INT J GYNECOL PATHOL. 20, 2, p. 160-165 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression pattern of the AP-1 family in endometrial cancer: correlations with cell cycle regulators.
Bamberger, A. M., Milde-Langosch, K., Rössing, E., Goemann, C. & Löning, T., 2001, In: J CANCER RES CLIN. 127, 9, p. 545-550 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Frequent p16/MTS1 inactivation in early stages of urothelial carcinoma of the bladder is not associated with tumor recurrence.
Friedrich, M., Blind, C., Milde-Langosch, K., Erbersdobler, A., Conrad, S., Löning, T., Hammerer, P. & Huland, H., 2001, In: EUR UROL. 40, 5, p. 518-524 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene-expression profiles in hereditary breast cancer.
Hedenfalk, I., Duggan, D., Chen, Y., Radmacher, M., Bittner, M., Simon, R., Meltzer, P., Gusterson, B., Esteller, M., Kallioniemi, O. P., Wilfond, B., Borg, A., Trent, J., Raffeld, M., Yakhini, Z., Ben-Dor, A., Dougherty, E., Kononen, J., Bubendorf, L., Fehrle, W., Pittaluga, S., Gruvberger, S., Loman, N., Johannsson, O., Olsson, H. & Sauter, G., 2001, In: NEW ENGL J MED. 344, 8, p. 539-548 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High-throughput tissue microarray analysis of 3p25 (RAF1) and 8p12 (FGFR1) copy number alterations in urinary bladder cancer.
Simon, R., Richter, J., Wagner, U., Fijan, A., Bruderer, J., Schmid, U., Ackermann, D., Maurer, R., Alund, G., Knönagel, H., Rist, M., Wilber, K., Anabitarte, M., Hering, F., Hardmeier, T., Schönenberger, A., Flury, R., Jäger, P., Fehr, J. L., Schraml, P., Moch, H., Mihatsch, M. J., Gasser, T. & Sauter, G., 2001, In: CANCER RES. 61, 11, p. 4514-4519 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification and analysis of a new hepadnavirus in white storks.
Pult, I., Netter, H. J., Bruns, M., Prassolov, A., Sirma, H., Hohenberg, H., Chang, S. F., Frölich, K., Krone, O., Kaleta, E. F. & Will, H., 2001, In: VIROLOGY. 289, 1, p. 114-128 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunohistochemical analysis of the proliferative activity of neuroendocrine tumors from various organs. Are there indications for a neuroendocrine tumor-carcinoma sequence?
Helpap, B. & Köllermann, J., 2001, In: VIRCHOWS ARCH. 438, 1, p. 86-91 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Limiting the diagnosis of atypical small glandular proliferations in needle biopsies of the prostate by the use of immunohistochemistry.
Helpap, B., Köllermann, J. & Oehler, U., 2001, In: J PATHOL. 193, 3, p. 350-353 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MAGE-A gene expression pattern in primary breast cancer.
Otte, M., Zafrakas, M., Riethdorf, L., Pichlmeier, U., Löning, T., Jänicke, F. & Pantel, K., 2001, In: CANCER RES. 61, 18, p. 6682-6687 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review