II. Department of Medicine

Publications

  1. 2004
  2. Prospective multicenter phase II study of irinotecan as third-line therapy in metastatic colorectal cancer and progression after bolus and infusional 5-fluorouracil

    Hartmann, J. T., Oechsle, K., Jäger, E., Reis, H. E., Haag, C., Niederle, N., Wilke, H-J., Pflüger, K-H., Batran, S. A., Büchele, T., Hofheinz, R. D., Kanz, L. & Bokemeyer, C., 06.2004, In: ANTI-CANCER DRUG. 15, 5, p. 473-7 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. The role of [(18)F] FDG-PET, CT/MRI and tumor marker kinetics in the evaluation of post chemotherapy residual masses in metastatic germ cell tumors--prospects for management

    Pfannenberg, A. C., Oechsle, K., Bokemeyer, C., Kollmannsberger, C., Dohmen, B. M., Bares, R., Hartmann, J. T., Vonthein, R. & Claussen, C. D., 06.2004, In: WORLD J UROL. 22, 2, p. 132-9 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. 2-18fluoro-deoxy-D-glucose positron emission tomography is a reliable predictor for viable tumor in postchemotherapy seminoma: an update of the prospective multicentric SEMPET trial

    De Santis, M., Becherer, A., Bokemeyer, C., Stoiber, F., Oechsle, K., Sellner, F., Lang, A., Kletter, K., Dohmen, B. M., Dittrich, C. & Pont, J., 15.03.2004, In: J CLIN ONCOL. 22, 6, p. 1034-9 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. [ ¹⁸F]FDG-PET, CT/MRT und Tumormarker als prädiktive Indikatoren für das Ansprechen unter Hochdosis-Chemotherapie bei Patienten mit metastasierten Keimzelltumoren

    Pfannenberg, A. C., Oechsle, K., Kollmannsberger, C., Dohmen, B. M., Bokemeyer, C., Bares, R., Vontheim, R. & Claussen, C. D., 01.2004, In: ROFO-FORTSCHR RONTG. 176, 1, p. 76-84 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. An in vitro study on the mechanisms of coagulation activation in acute myelogenous leukemia (AML): role of tissue factor regulation by cytotoxic drugs and GM-CSF.

    Langer, F., Amirkhosravi, A., Loges, S., Meyer, T., Eifrig, B., Hossfeld, D. K., Fiedler, W. & Francis, J. L., 2004, In: THROMB HAEMOSTASIS. 92, 5, p. 1136-1146 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Cell type-specific expression of LINE-1 open reading frames 1 and 2 in fetal and adult human tissues.

    Ergün, S., Buschmann, C., Heukeshoven, J., Dammann, K., Schnieders, F., Lauke, H., Chalajour, F., Kilic, N., Strätling, W. H. & Schumann, G. G., 2004, In: J BIOL CHEM. 279, 26, p. 27753-27763 26.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. [Clinical presentation, diagnosis and treatment of Mycoplasma pneumoniae pneumonia]

    Kluge, S., Azizi, M., Baumann, H. J., Meyer, A. & Kirsten, D., 2004, In: PNEUMOLOGIE. 58, 10, p. 733-738 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Dicentric (19;21)(p13;p13), a novel chromosomal abnormality occurring in a case of Philadelphia chromosome-positive acute lymphoblastic leukemia.

    Schilling, G., Dierlamm, J., Murga-Penas, E-M., Hinz, K., Seeger, D. & Hossfeld, D. K., 2004, In: CANCER GENET-NY. 152, 2, p. 129-131 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Dual role of carcinoembryonic antigen-related cell adhesion molecule 1 in angiogenesis and invasion of human urinary bladder cancer.

    Oliveira-Ferrer, L., Tilki, D., Ziegeler, G., Hauschild, J., Loges, S., Irmak, S., Kilic, E., Huland, H., Friedrich, M. & Ergün, S., 2004, In: CANCER RES. 64, 24, p. 8932-8938 24.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Expression of carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) in normal human Sertoli cells and its up-regulation in impaired spermatogenesis.

    Lauke, H., Kilic, N., Bozorgzad, R., Fernando, M., Neshat-Vahid, S., Pottek, T. & Ergun, S., 2004, In: MOL HUM REPROD. 10, 4, p. 247-252 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Identification of the adult human hemangioblast.

    Loges, S., Fehse, B., Brockmann, M. A., Lamszus, K., Butzal, M., Guckenbiehl, M., Schuch, G., Ergün, S., Fischer, U., Zander, A. R., Hossfeld, D. K., Fiedler, W. & Gehling, U., 2004, In: STEM CELLS DEV. 13, 3, p. 229-242 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. [Noninvasive mechanical ventilation in patients with stable severe COPD]

    Schucher, B., Zerbst, J. & Baumann, H. J., 2004, In: PNEUMOLOGIE. 58, 6, p. 428-434 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Percutaneous tracheostomy is safe in patients with severe thrombocytopenia.

    Kluge, S., Meyer, A., Kühnelt, P., Baumann, H. J. & Kreymann, G., 2004, In: CHEST. 126, 2, p. 547-551 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Rapamycin inhibits proliferation and differentiation of human endothelial progenitor cells in vitro.

    Butzal, M., Loges, S., Schweizer, M., Fischer, U., Gehling, U., Hossfeld, D. K. & Fiedler, W., 2004, In: EXP CELL RES. 300, 1, p. 65-71 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. The future of clinical cancer research: who's teaching the next generation? The Flims-Vail model.

    Palmieri, C., Wanaski, S., Panse, J. & Medeiros, B., 2004, In: EUR J CANCER. 40, 2, p. 173-175 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. 2003
  18. Protracted infusional 5-fluorouracil plus high-dose folinic acid combined with bolus mitomycin C in patients with gastrointestinal cancer: a phase I/II dose escalation study

    Hartmann, J. T., Oechsle, K., Quietzsch, D., Wein, A., Hofheinz, R. D., Honecker, F., Nehls, O., Köhne, C-H., Käfer, G., Kanz, L. & Bokemeyer, C., 01.12.2003, In: BRIT J CANCER. 89, 11, p. 2051-6 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. An open label, non-comparative phase II study of topotecan as salvage treatment for patients with soft tissue sarcoma

    Reichardt, P., Oechsle, K., Pink, D., Bokemeyer, C., Schneller, F., Issels, R., Kanz, L. & Hartmann, J. T., 11.2003, In: INVEST NEW DRUG. 21, 4, p. 481-6 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Promyelocytic leukaemia zinc finger protein (PLZF) is a glucocorticoid- and progesterone-induced transcription factor in human endometrial stromal cells and myometrial smooth muscle cells

    Fahnenstich, J., Nandy, A., Milde-Langosch, K., Schneider-Merck, T., Walther, N. & Gellersen, B., 10.2003, In: MOL HUM REPROD. 9, 10, p. 611-23 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Structure of the murine tenascin-R gene and functional characterisation of the promoter

    Putthoff, P., Akyüz, N., Kutsche, M., Zardi, L., Borgmeyer, U. & Schachner, M., 05.09.2003, In: BIOCHEM BIOPH RES CO. 308, 4, p. 940-9 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair

    Boehden, G. S., Akyüz, N., Roemer, K. & Wiesmüller, L., 26.06.2003, In: ONCOGENE. 22, 26, p. 4111-7 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Phase II trial of trofosfamide in patients with advanced pretreated soft tissue sarcomas

    Hartmann, J. T., Oechsle, K., Mayer, F., Kanz, L. & Bokemeyer, C., 25.06.2003, In: ANTICANCER RES. 23, 2C, p. 1899-901 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Cloning and cortical expression of rat Emx2 and adenovirus-mediated overexpression to assess its regulation of area-specific targeting of thalamocortical axons

    Leingärtner, A., Richards, L. J., Dyck, R. H., Akazawa, C. & O'Leary, D. D. M., 01.06.2003, In: CEREB CORTEX. 13, 6, p. 648-60 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. A novel cryptic translocation t(12;17)(p13;p12-p13) in a secondary acute myeloid leukemia results in a fusion of the ETV6 gene and the antisense strand of the PER1 gene.

    Murga-Penas, E-M., Cools, J., Algenstaedt, P., Hinz, K., Seeger, D., Schafhausen, P., Schilling, G., Marynen, P., Hossfeld, D. K. & Dierlamm, J., 2003, In: GENE CHROMOSOME CANC. 37, 1, p. 79-83 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. A phase 2 clinical study of SU5416 in patients with refractory acute myeloid leukemia.

    Fiedler, W., Mesters, R., Tinnefeld, H., Loges, S., Staib, P., Duhrsen, U., Flasshove, M., Ottmann, O. G., Jung, W., Cavalli, F., Kuse, R., Thomalla, J., Serve, H., O'Farrell, A. M., Jacobs, M., Brega, N. M., Scigalla, P., Hossfeld, D. K. & Berdel, W. E., 2003, In: BLOOD. 102, 8, p. 2763-2767 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Deletion of chromosome 15 represents a rare but recurrent chromosomal abnormality in myelocytic malignancies.

    Dierlamm, J., Schilling, G., Michaux, L., Hinz, K., Murga-Penas, E-M., Seeger, D., Hagemeijer, A. & Hossfeld, D. K., 2003, In: CANCER GENET-NY. 144, 1, p. 1-5 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Dog leukocyte antigen nonidentical unrelated canine marrow grafts: enhancement of engraftment by CD4 and CD8 T cells.

    Panse, J., Bastianelli, C., Santos, E. B., Schwarzinger, I., Raff, R. F., Storb, R. & Sandmaier, B. M., 2003, In: TRANSPLANTATION. 76, 3, p. 474-480 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Evaluation of health-related quality of life using the MOS 36-Item Short-Form Health Status Survey in patients receiving noninvasive positive pressure ventilation.

    Windisch, W., Freidel, K., Schucher, B., Baumann, H. J., Wiebel, M., Matthys, H. & Petermann, F., 2003, In: INTENS CARE MED. 29, 4, p. 615-621 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Proof of principle: detection of genotoxicity by a fluorescence-based recombination test in mammalian cells

    Akyüz, N. & Wiesmüller, L., 2003, In: ALTEX-ALTERN ANIM EX. 20, 2, p. 77-84 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. The Severe Respiratory Insufficiency (SRI) Questionnaire: a specific measure of health-related quality of life in patients receiving home mechanical ventilation.

    Windisch, W., Freidel, K., Schucher, B., Baumann, H. J., Wiebel, M., Matthys, H. & Petermann, F., 2003, In: J CLIN EPIDEMIOL. 56, 8, p. 752-759 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Translocations t(11;18)(q21;q21) and t(14;18)(q32;q21) are the main chromosomal abnormalities involving MLT/MALT1 in MALT lymphomas.

    Murga-Penas, E-M., Hinz, K., Röser, K., Copie-Bergman, C., Wlodarska, I., Marynen, P., Hagemeijer, A., Gaulard, P., Löning, T., Hossfeld, D. K. & Dierlamm, J., 2003, In: LEUKEMIA. 17, 11, p. 2225-2229 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. 2002
  34. Treatment-induced anaemia and its potential clinical impact in patients receiving sequential high dose chemotherapy for metastatic testicular cancer

    Bokemeyer, C., Oechsle, K., Hartmann, J. T., Schöffski, P., Schleucher, N., Metzner, B., Schleicher, J. & Kanz, L., 04.11.2002, In: BRIT J CANCER. 87, 10, p. 1066-71 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Expression of CEACAM1 in adenocarcinoma of the lung: a factor of independent prognostic significance

    Laack, E., Nikbakht, H., Peters, A., Kugler, C., Jasiewicz, Y., Edler, L., Brümmer, J., Schumacher, U. & Hossfeld, D. K., 01.11.2002, In: J CLIN ONCOL. 20, 21, p. 4279-84 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Autophagocytosis of the apical membrane in microvillus inclusion disease

    Reinshagen, K., Naim, H. Y. & Zimmer, K-P., 10.2002, In: GUT. 51, 4, p. 514-21 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. DNA substrate dependence of p53-mediated regulation of double-strand break repair

    Akyüz, N., Boehden, G. S., Süsse, S., Rimek, A., Preuss, U., Scheidtmann, K-H. & Wiesmüller, L., 09.2002, In: MOL CELL BIOL. 22, 17, p. 6306-17 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Prospective comparison of [18F]fluorodeoxyglucose positron emission tomography with conventional assessment by computed tomography scans and serum tumor markers for the evaluation of residual masses in patients with nonseminomatous germ cell carcinoma

    Kollmannsberger, C., Oechsle, K., Dohmen, B. M., Pfannenberg, A., Bares, R., Claussen, C. D., Kanz, L. & Bokemeyer, C., 01.05.2002, In: CANCER-AM CANCER SOC. 94, 9, p. 2353-62 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Lectin histochemistry of resected adenocarcinoma of the lung: helix pomatia agglutinin binding is an independent prognostic factor

    Laack, E., Nikbakht, H., Peters, A., Kugler, C., Jasiewicz, Y., Edler, L., Hossfeld, D. K. & Schumacher, U., 03.2002, In: AM J PATHOL. 160, 3, p. 1001-8 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

    Arakawa, H., Hauschild, J. & Buerstedde, J-M., 15.02.2002, In: SCIENCE. 295, 5558, p. 1301-6 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Early prediction of treatment response to high-dose salvage chemotherapy in patients with relapsed germ cell cancer using [(18)F]FDG PET

    Bokemeyer, C., Kollmannsberger, C., Oechsle, K., Dohmen, B. M., Pfannenberg, A., Claussen, C. D., Bares, R. & Kanz, L., 12.02.2002, In: BRIT J CANCER. 86, 4, p. 506-11 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Dose-reduced conditioning regimen followed by allogeneic stem cell transplantation in patients with myelofibrosis with myeloid metaplasia.

    Hessling, J., Kröger, N-M., Werner, M., Zabelina, T., Hansen, A., Kordes, U., Ayuketang Ayuk, F., Renges, H-H., Panse, J., Erttmann, R. & Zander, A., 2002, In: BRIT J HAEMATOL. 119, 3, p. 769-772 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Highly efficient retroviral gene transfer based on centrifugation-mediated vector preloading of tissue culture vessels.

    Kühlcke, K., Fehse, B., Schilz, A., Loges, S., Lindemann, C., Ayuketang Ayuk, F., Lehmann, F., Stute, N., Fauser, A. A., Zander, A. R. & Eckert, H-G., 2002, In: MOL THER. 5, 4, p. 473-478 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Spontaneous bacterial peritonitis due to Listeria monocytogenes in a patient with primary pulmonary hypertension.

    Rohde, H., Horstkotte, M. A., Sobottka, I., Klose, H. & Mack, D., 2002, In: EUR J CLIN MICROBIOL. 21, 4, p. 323-325 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. The novel t(11;12;18)(q21;q13;q21) represents a variant translocation of the t(11;18)(q21;q21) associated with MALT-type lymphoma.

    Dierlamm, J., Murga-Penas, E-M., Daibata, M., Tagushi, H., Hinz, K., Baens, M., Cools, J., Schilling, G., Michaux, L., Marynen, P., Miyoshi, I. & Hossfeld, D. K., 2002, In: LEUKEMIA. 16, 9, p. 1863-1864 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Tumor oxygenation under combined whole-body-hyperthermia and polychemotherapy in a case of recurrent carcinoma of the oral cavity.

    Sagowski, C., Jaehne, M., Kehrl, W., Hegewisch-Becker, S., Wenzel, S., Panse, J. & Nierhaus, A., 2002, In: EUR ARCH OTO-RHINO-L. 259, 1, p. 27-31 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. 2001
  48. Semiquantitative reverse transcription polymerase chain reaction analysis for detection of bcr/abl rearrangement using RNA extracts from bone marrow aspirates compared with glass slide smears after 0, 2 and 4 d of storage

    Schoch, R., Pitako, J., Schafhausen, P., Jenisch, S., Haferlach, T., Kneba, M. & Suttorp, M., 12.2001, In: BRIT J HAEMATOL. 115, 3, p. 583-7 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Predictive impact of 2-18fluoro-2-deoxy-D-glucose positron emission tomography for residual postchemotherapy masses in patients with bulky seminoma

    De Santis, M., Bokemeyer, C., Becherer, A., Stoiber, F., Oechsle, K., Kletter, K., Dohmen, B. M., Dittrich, C. & Pont, J., 01.09.2001, In: J CLIN ONCOL. 19, 17, p. 3740-4 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Chromosomal gains and losses are uncommon in hairy cell leukemia: a study based on comparative genomic hybridization and interphase fluorescence in situ hybridization.

    Dierlamm, J., Stefanova, M., Wlodarska, I., Michaux, L., Hinz, K., Murga-Penas, E-M., Maes, B., Hagemeijer, A., De Wolf-Peeters, C. & Hossfeld, D. K., 2001, In: CANCER GENET-NY. 128, 2, p. 164-167 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Endostatin inhibits angiogenesis by stabilization of newly formed endothelial tubes.

    Ergün, S., Kilic, N., Wurmbach, J. H., Ebrahimnejad, A., Fernando, M., Sevinc, S., Kilic, E., Chalajour, F., Fiedler, W., Lauke, H., Lamszus, K., Hammerer, P., Weil, J., Herbst, H. & Folkman, J., 2001, In: ANGIOGENESIS. 4, 3, p. 193-206 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. 2000
  53. Derivation of a new hematopoietic cell line with endothelial features from a patient with transformed myeloproliferative syndrome: a case report.

    Fiedler, W., Henke, R. P., Ergün, S., Schumacher, U., Gehling, U. M., Vohwinkel, G., Kilic, N. & Hossfeld, D. K., 2000, In: CANCER-AM CANCER SOC. 88, 2, p. 344-351 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  54. Dose-dependent effect of etoposide in combination with busulfan plus cyclophosphamide as conditioning for stem cell transplantation in patients with acute myeloid leukemia.

    Kröger, N., Zabelina, T., Sonnenberg, S., Krüger, W., Renges, H., Stute, N., Finkenstein, F., Mayer, U., Holstein, K., Fiedler, W., Colberg, H., Sonnen, R., Kuse, R., Braumann, D., Metzner, B., Del Valle, F., Erttmann, R., Kabisch, H. & Zander, A. R., 2000, In: BONE MARROW TRANSPL. 26, 7, p. 711-716 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  55. In vitro differentiation of endothelial cells from AC133-positive progenitor cells.

    Gehling, U. M., Ergün, S., Schumacher, U., Wagener, C., Pantel, K., Otte, M., Schuch, G., Schafhausen, P., Mende, T., Kilic, N., Kluge, K., Schäfer, B., Hossfeld, D. K. & Fiedler, W., 2000, In: BLOOD. 95, 10, p. 3106-3112 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review