Core Facilities

Publications

  1. 2016
  2. Correlation of somatic mutations with outcome after FLAMSA-busulfan sequential conditioning and allogeneic stem cell transplantation in patients with MDS

    Christopeit, M., Badbaran, A., Alawi, M., Zabelina, T., Zeck, G., Wolschke, C., Ayuketang, F. A. & Kröger, N., 01.09.2016, In: EUR J HAEMATOL. 97, 3, p. 288-96

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. A novel multiple joint dislocation syndrome associated with a homozygous nonsense variant in the EXOC6B gene

    Girisha, K. M., Kortüm, F., Shah, H., Alawi, M., Dalal, A., Bhavani, G. S. & Kutsche, K., 01.08.2016, In: EUR J HUM GENET. 24, 8, p. 1206-10

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Homozygous HOXB1 loss-of-function mutation in a large family with hereditary congenital facial paresis

    Vogel, M., Velleuer, E., Schmidt-Jiménez, L. F., Mayatepek, E., Borkhardt, A., Alawi, M., Kutsche, K. & Kortüm, F., 07.2016, In: AM J MED GENET A. 170, 7, p. 1813-9 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Pegivirus Infection in Domestic Pigs, Germany

    Baechlein, C., Grundhoff, A., Fischer, N., Alawi, M., Hoeltig, D., Waldmann, K-H. & Becher, P., 07.2016, In: EMERG INFECT DIS. 22, 7, p. 1312-4 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  6. Runx1 downregulates stem cell and megakaryocytic transcription programs that support niche interactions

    Behrens, K., Triviai, I., Schwieger, M., Tekin, N., Alawi, M., Spohn, M., Indenbirken, D., Ziegler, M., Müller, U., Alexander, W. S. & Stocking, C., 30.06.2016, In: BLOOD. 127, 26, p. 3369-81 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. A transplant “immunome” screening platform defines a targetable epitope fingerprint of multiple myeloma

    Schieferdecker, A., Oberle, A., Thiele, B., Hofmann, F., Göthel, M., Miethe, S., Hust, M., Braig, F., Voigt, M., Pein, U-M., Nolte, F., Haag, F., Alawi, M., Indenbirken, D., Grundhoff, A., Bokemeyer, C., Bacher, U., Kröger, N. & Binder, M., 23.06.2016, In: BLOOD. 127, 25, p. 3202-14

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells

    Berneking, L., Schnapp, M., Rumm, A., Trasak, C., Ruckdeschel, K., Alawi, M., Grundhoff, A., Kikhney, A. G., Nolte, F., Buck, F., Perbandt, M., Betzel, C., Svergun, D. I., Hentschke, M. & Aepfelbacher, M., 13.06.2016, In: PLOS PATHOG. 12, 6, p. e1005660

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. IL-23 prevents IL-13-dependent tissue repair associated with Ly6C(lo) monocytes in Entamoeba histolytica-induced liver damage

    Noll, J., Helk, E., Fehling, H., Bernin, H., Marggraff, C., Jacobs, T., Huber, S., Pelczar, P., Ernst, T., Ittrich, H., Otto, B., Mittrücker, H-W., Hölscher, C., Tacke, F., Bruchhaus, I., Tannich, E. & Lotter, H., 05.2016, In: J HEPATOL. 64, 5, p. 1147-57

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Functional dissection of an alternatively spliced herpesvirus gene by splice site mutagenesis

    Schommartz, T., Loroch, S., Alawi, M., Grundhoff, A., Sickmann, A. & Brune, W., 14.04.2016, In: J VIROL. 90, 9, p. 4626-36

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Rapid Capture Next-Generation Sequencing in Clinical Diagnostics of Kinase Pathway Aberrations in B-Cell Precursor ALL

    Stadt, U. Z., Escherich, G., Indenbirken, D., Alawi, M., Adao, M. & Horstmann, M. A., 23.03.2016, In: PEDIATR BLOOD CANCER. 63, 7, p. 1283-6

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  12. Reelin and cofilin cooperate during the migration of cortical neurons: a quantitative morphological analysis

    Chai, X., Zhao, S., Fan, L., Zhang, W., Lu, X., Shao, H., Wang, S., Song, L., Failla, A. V., Zobiak, B., Mannherz, H. G. & Frotscher, M., 15.03.2016, In: DEVELOPMENT. 143, 6, p. 1029-40 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Essential control of early B-cell development by Mef2 transcription factors

    Herglotz, J., Unrau, L., Hauschildt, F., Fischer, M., Kriebitzsch, N., Alawi, M., Indenbirken, D., Spohn, M., Müller, U., Ziegler, M., Schuh, W., Jäck, H-M. & Stocking, C., 04.02.2016, In: BLOOD. 127, 5, p. 572-81 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Deep metagenome and metatranscriptome analyses of microbial communities affiliated with an industrial biogas fermenter, a cow rumen, and elephant feces reveal major differences in carbohydrate hydrolysis strategies

    Güllert, S., Fischer, M. A., Turaev, D., Noebauer, B., Ilmberger, N., Wemheuer, B., Alawi, M., Rattei, T., Daniel, R., Schmitz, R. A., Grundhoff, A. & Streit, W. R., 2016, In: BIOTECHNOL BIOFUELS. 9, p. 121

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Systems Medicine as an Emerging Tool for Cardiovascular Genetics

    Haase, T., Börnigen, D., Müller, C. & Zeller, T., 2016, In: FRONT CARDIOVASC MED. 3, p. 27

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  16. 2015
  17. Tight junctions form a barrier in porcine hair follicles

    Mathes, C., Brandner, J. M., Laue, M., Raesch, S. S., Hansen, S., Failla, A. V., Vidal, S., Moll, I., Schaefer, U. F. & Lehr, C-M., 29.12.2015, In: EUR J CELL BIOL. 95, 2, p. 89-99

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Analysis of Yersinia enterocolitica Effector Translocation into Host Cells Using Beta-lactamase Effector Fusions.

    Wolters, M., Zobiak, B., Nauth, T. & Aepfelbacher, M., 13.10.2015, In: JOVE-J VIS EXP. 104

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Emergence of daptomycin non-susceptibility in colonizing vancomycin-resistant Enterococcus faecium isolates during daptomycin therapy

    Lellek, H., Franke, G. C., Ruckert, C., Wolters, M., Wolschke, C., Christner, M., Büttner, H., Alawi, M., Kröger, N. & Rohde, H., 12.09.2015, In: INT J MED MICROBIOL. 305, 8, p. 902-909

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence

    Theiss, J. M., Günther, T., Alawi, M., Neumann, F., Tessmer, U., Fischer, N. & Grundhoff, A., 07.2015, In: PLOS PATHOG. 11, 7, p. e1004974

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples

    Fischer, N., Indenbirken, D., Meyer, T., Lütgehetmann, M., Lellek, H., Spohn, M., Aepfelbacher, M., Alawi, M. & Grundhoff, A., 07.2015, In: J CLIN MICROBIOL. 53, 7, p. 2238-50 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Identification of a Novel Hepacivirus in Domestic Cattle from Germany

    Fischer, N., Baechlein, C., Grundhoff, A., Alawi, M., Indenbirken, D., Postel, A., Baron, A. L., Offinger, J., Becker, K., Beineke, A., Rehage, J. & Becher, P., 07.2015, In: J VIROL. 89, 14, p. 7007-15 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome

    Kortüm, F., Caputo, V., Bauer, C. K., Stella, L., Ciolfi, A., Alawi, M., Bocchinfuso, G., Flex, E., Paolacci, S., Dentici, M. L., Grammatico, P., Korenke, G. C., Leuzzi, V., Mowat, D., Nair, L. D. V., Nguyen, T. T. M., Thierry, P., White, S. M., Dallapiccola, B., Pizzuti, A., Campeau, P. M., Tartaglia, M. & Kutsche, K., 01.06.2015, In: NAT GENET. 47, 6, p. 661-7 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Ex vivo aorta patch model for analysis of cellular adhesion

    Lin, Y-N., Thata, R. N., Failla, A. V., Geissen, M., Daum, G. & Windhorst, S., 06.2015, In: TISSUE CELL. 47, 3, p. 266-272 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer

    Braig, F., März, M., Schieferdecker, A., Schulte, A., Voigt, M., Stein, A., Grob, T., Alawi, M., Indenbirken, D., Kriegs, M., Engel, E., Vanhoefer, U., Grundhoff, A., Loges, S., Riecken, K., Fehse, B., Bokemeyer, C. & Binder, M., 20.05.2015, In: ONCOTARGET. 6, 14, p. 12035-47 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Single gold nanorods as optical probes for spectral imaging

    Wackenhut, F., Failla, A. V. & Meixner, A. J., 05.2015, In: ANAL BIOANAL CHEM. 407, 14, p. 4029-4034 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Mutations in NDUFB11, Encoding a Complex I Component of the Mitochondrial Respiratory Chain, Cause Microphthalmia with Linear Skin Defects Syndrome

    van Rahden, V. A., Fernandez-Vizarra, E., Alawi, M., Brand, K., Fellmann, F., Horn, D., Zeviani, M. & Kutsche, K., 02.04.2015, In: AM J HUM GENET. 96, 4, p. 640-50 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Deciphering the microRNA signature of pathological cardiac hypertrophy by engineered heart tissue- and sequencing-technology

    Hirt, M. N., Werner, T., Indenbirken, D., Alawi, M., Demin, P., Kunze, A-C., Stenzig, J., Starbatty, J., Hansen, A., Fiedler, J., Thum, T. & Eschenhagen, T., 01.04.2015, In: J MOL CELL CARDIOL. 81, p. 1-9 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Close relationship of ruminant pestiviruses and classical Swine Fever virus

    Postel, A., Schmeiser, S., Oguzoglu, T. C., Indenbirken, D., Alawi, M., Fischer, N., Grundhoff, A. & Becher, P., 04.2015, In: EMERG INFECT DIS. 21, 4, p. 668-72 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. An 18 kDa Scaffold Protein Is Critical for Staphylococcus epidermidis Biofilm Formation

    Decker, R., Burdelski, C., Zobiak, M., Büttner, H., Franke, G., Christner, M., Saß, K., Zobiak, B., Henke, H. A., Horswill, A. R., Bischoff, M., Bur, S., Hartmann, T., Schaeffer, C. R., Fey, P. D. & Rohde, H., 01.03.2015, In: PLOS PATHOG. 11, 3, p. e1004735

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. The catalytic domain of inositol-1,4,5-trisphosphate 3-kinase-a contributes to ITPKA-induced modulation of F-actin

    Ashour, D. J., Pelka, B., Jaaks, P., Wundenberg, T., Blechner, C., Zobiak, B., Failla, A. V. & Windhorst, S., 02.2015, In: CYTOSKELETON. 72, 2, p. 93-100 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts

    Deuse, T., Wang, D., Stubbendorff, M., Itagaki, R., Grabosch, A., Greaves, L. C., Alawi, M., Grünewald, A., Hu, X., Hua, X., Velden, J., Reichenspurner, H., Robbins, R. C., Jaenisch, R., Weissman, I. L. & Schrepfer, S., 08.01.2015, In: CELL STEM CELL. 16, 1, p. 33-38 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. An AP4B1 frameshift mutation in siblings with intellectual disability and spastic tetraplegia further delineates the AP-4 deficiency syndrome

    Abdollahpour, H., Alawi, M., Kortüm, F., Beckstette, M., Seemanova, E., Komárek, V., Rosenberger, G. & Kutsche, K., 2015, In: EUR J HUM GENET. 23, 2, p. 256-259

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. 2014
  35. Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription

    Nagarajan, S., Hossan, T., Alawi, M., Najafova, Z., Indenbirken, D., Bedi, U., Taipaleenmäki, H., Ben-Batalla, I., Scheller, M., Loges, S., Knapp, S., Hesse, E., Chiang, C-M., Grundhoff, A. & Johnsen, S. A., 24.07.2014, In: CELL REP. 8, 2, p. 459-468 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Next-generation sequencing of peripheral B-lineage cells pinpoints the circulating clonotypic cell pool in multiple myeloma

    Thiele, B., Kloster, M., Alawi, M., Indenbirken, D., Trepel, M., Grundhoff, A. & Binder, M., 05.06.2014, In: BLOOD. 123, 23, p. 3618-21 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Rapid Metagenomic Diagnostics for Suspected Outbreak of Severe Pneumonia

    Fischer, N., Rohde, H., Indenbirken, D., Günther, T., Reumann, K., Lütgehetmann, M., Meyer, T., Kluge, S., Aepfelbacher, M., Alawi, M. & Grundhoff, A., 01.06.2014, In: EMERG INFECT DIS. 20, 6, p. 1072-5 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  38. A comparative metagenome survey of the fecal microbiota of a breast- and a plant-fed Asian elephant reveals an unexpectedly high diversity of glycoside hydrolase family enzymes

    Ilmberger, N., Güllert, S., Dannenberg, J., Rabausch, U., Torres, J., Wemheuer, B., Alawi, M., Poehlein, A., Chow, J., Turaev, D., Rattei, T., Schmeisser, C., Salomon, J., Olsen, P. B., Daniel, R., Grundhoff, A., Borchert, M. S. & Streit, W. R., 2014, In: PLOS ONE. 9, 9, p. e106707

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. 2013
  40. Metagenome survey of a multispecies and alga-associated biofilm revealed key elements of bacterial-algal interactions in photobioreactors

    Krohn-Molt, I., Wemheuer, B., Alawi, M., Poehlein, A., Güllert, S., Schmeisser, C., Pommerening-Röser, A., Grundhoff, A., Daniel, R., Hanelt, D. & Streit, W. R., 10.2013, In: APPL ENVIRON MICROB. 79, 20, p. 6196-6206 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer

    Werner, S., Frey, S., Riethdorf, S., Schulze, C., Alawi, M., Kling, L., Vafaizadeh, V., Sauter, G., Terracciano, L., Schumacher, U., Pantel, K. & Assmann, V., 09.08.2013, In: J BIOL CHEM. 288, 32, p. 22993-3008 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Runx1 is essential at two stages of early murine B-cell development

    Niebuhr, B., Kriebitzsch, N., Fischer, M., Behrens, K., Günther, T., Alawi, M., Bergholz, U., Müller, U., Roscher, S., Ziegler, M., Buchholz, F., Grundhoff, A. & Stocking, C., 18.07.2013, In: BLOOD. 122, 3, p. 413-23 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Sensing dielectric media on the nanoscale with freely oriented gold nanorods

    Wackenhut, F., Failla, A. V. & Meixner, A. J., 21.04.2013, In: PHYS CHEM CHEM PHYS. 15, 15, p. 5407-5414 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. 2011
  45. CASSys: an integrated software-system for the interactive analysis of ChIP-seq data

    Alawi, M., Kurtz, S. & Beckstette, M., 2011, In: J INTEGR BIOINFORMAT. 8, 2, p. 155

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. 2010
  47. Stereotypical chronic lymphocytic leukemia B-cell receptors recognize survival promoting antigens on stromal cells

    Binder, M., Léchenne, B., Ummanni, R., Scharf, C., Balabanov, S., Trusch, M., Schlüter, H., Braren, I., Spillner, E. & Trepel, M., 30.12.2010, In: PLOS ONE. 5, 12, p. e15992

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. 2001
  49. The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein

    Gauczynski, S., Peyrin, J. M., Haïk, S., Leucht, C., Hundt, C., Rieger, R., Krasemann, S., Deslys, J. P., Dormont, D., Lasmézas, C. I. & Weiss, S., 01.11.2001, In: EMBO J. 20, 21, p. 5863-75 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Previous 1 2 3 4 Next