MOL CANCER THER - Molecular cancer therapeutics
Publications
- 2019
An EGFR-induced Drosophila lung tumor model identifies alternative combination treatments
Bossen, J., Uliczka, K., Steen, L., Pfefferkorn, R., Mai, M. M-Q., Burkhardt, L., Spohn, M., Bruchhaus, I., Fink, C., Heine, H. & Roeder, T., 09.2019, In: MOL CANCER THER. 18, 9, p. 1659-1668 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nanobody-targeting of epidermal growth factor receptor (EGFR) ectodomain variants overcomes resistance to therapeutic EGFR antibodies
Tintelnot, J., Baum, N., Schultheiss, C., Braig, F., Trentmann, M., Finter, J., Fumey, W., Bannas, P., Fehse, B., Riecken, K., Schütze, K., Bokemeyer, C., Rösner, T., Valerius, T., Peipp, M., Koch-Nolte, F. & Binder, M., 04.2019, In: MOL CANCER THER. 18, 4, p. 823-833 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
HER2 Status in Advanced or Metastatic Gastric, Esophageal, or Gastroesophageal Adenocarcinoma for Entry to the TRIO-013/LOGiC Trial of Lapatinib
Press, M. F., Ellis, C. E., Gagnon, R. C., Grob, T. J., Buyse, M., Villalobos, I., Liang, Z., Wu, S., Bang, Y-J., Qin, S-K., Chung, H. C., Xu, J., Park, J. O., Jeziorski, K., Afenjar, K., Ma, Y., Estrada, M. C., Robinson, D. M., Scherer, S. J., Sauter, G., Hecht, J. R. & Slamon, D. J., 01.2017, In: MOL CANCER THER. 16, 1, p. 228-238 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Targeting Homologous Recombination by Pharmacological Inhibitors Enhances the Killing Response of Glioblastoma Cells Treated with Alkylating Drugs
Berte, N., Piée-Staffa, A., Piecha, N., Wang, M., Borgmann, K., Kaina, B. & Nikolova, T., 11.2016, In: MOL CANCER THER. 15, 11, p. 2665-2678 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD20-Targeting Immunotherapy Promotes Cellular Senescence in B-Cell Lymphoma
Yu, Y., Schönlein, M., Kaufmann, A. M., Dörken, B. & Schmitt, C. A., 05.2016, In: MOL CANCER THER. 15, 5, p. 1074-81 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Effects of BRAF mutations and BRAF inhibition on immune responses to melanoma
Ilieva, K. M., Correa, I., Josephs, D. H., Karagiannis, P., Egbuniwe, I. U., Cafferkey, M. J., Spicer, J. F., Harries, M., Nestle, F. O., Lacy, K. E. & Karagiannis, S. N., 12.2014, In: MOL CANCER THER. 13, 12, p. 2769-83 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1)
Decker, S., Finter, J., Forde, A. J., Kissel, S., Schwaller, J., Mack, T. S., Kuhn, A., Gray, N., Follo, M., Jumaa, H., Burger, M., Zirlik, K., Pfeifer, D., Miduturu, C. V., Eibel, H., Veelken, H. & Dierks, C., 05.2014, In: MOL CANCER THER. 13, 5, p. 1231-45 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interferon-β induces loss of spherogenicity and overcomes therapy resistance of glioblastoma stem cells
Happold, C., Roth, P., Silginer, M., Florea, A-M., Lamszus, K., Frei, K., Deenen, R., Reifenberger, G. & Weller, M., 2014, In: MOL CANCER THER. 13, 4, p. 948-961 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Therapeutic potential of the poly(ADP-ribose) polymerase inhibitor rucaparib for the treatment of sporadic human ovarian cancer
Henningsen, M., zu Eulenburg, C., Kolarova, T., Qi, J. W., Manivong, K., Chalukya, M., Dering, J., Anderson, L., Ginther, C., Meuter, A., Winterhoff, B., Jones, S., Velculescu, V. E., Venkatesan, N., Rong, H-M., Dandekar, S., Udar, N., Jänicke, F., Los, G., Slamon, D. J. & Konecny, G. E., 01.06.2013, In: MOL CANCER THER. 12, 6, p. 1002-15 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Association of polymorphisms in AKT1 and EGFR with clinical outcome and toxicity in non-small cell lung cancer patients treated with gefitinib
Giovannetti, E., Zucali, P. A., Peters, G. J., Cortesi, F., D'Incecco, A., Smit, E. F., Falcone, A., Burgers, J. A., Santoro, A., Danesi, R., Giaccone, G. & Tibaldi, C., 03.2010, In: MOL CANCER THER. 9, 3, p. 581-93 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disabling c-Myc in childhood medulloblastoma and atypical teratoid/rhabdoid tumor cells by the potent G-quadruplex interactive agent S2T1-6OTD.
Shalaby, T., von Bueren, A., André, O., Hürlimann, M-L., Fiaschetti, G., Castelletti, D., Masayuki, T., Nagasawa, K., Arcaro, A., Jelesarov, I., Shin-ya, K. & Grotzer, M., 2010, In: MOL CANCER THER. 9, 1, p. 167-179 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effective therapeutic targeting of the overexpressed HER-2 receptor in a highly metastatic orthotopic model of esophageal carcinoma.
Gros, S., Kurschat, N., Dohrmann, T., Reichelt, U., Dancau, A. M., Peldschus, K., Adam, G., Hoffman, R. M., Izbicki, J. R. & Kaifi, J., 2010, In: MOL CANCER THER. 9, 7, p. 2037-2045 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines
Crea, F., Giovannetti, E., Cortesi, F., Mey, V., Nannizzi, S., Gallegos Ruiz, M. I., Ricciardi, S., Del Tacca, M., Peters, G. J. & Danesi, R., 07.2009, In: MOL CANCER THER. 8, 7, p. 1964-73 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer.
Trepel, M., Stoneham, C. A., Eleftherohorinou, H., Mazarakis, N. D., Pasqualini, R., Arap, W. & Hajitou, A., 2009, In: MOL CANCER THER. 8, 8, p. 2383-2391 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular determinants of response to matuzumab in combination with paclitaxel for patients with advanced non-small cell lung cancer.
Schittenhelm, M. M., Kollmannsberger, C., Oechsle, K., Harlow, A., Morich, J., Honecker, F., Kurek, R., Störkel, S., Kanz, L., Corless, C. L., Wong, K-K., Bokemeyer, C. & Heinrich, M. C., 2009, In: MOL CANCER THER. 8, 3, p. 481-489 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Tumor-associated CD75s- and iso-CD75s-gangliosides are potential targets for adjuvant therapy in pancreatic cancer
Distler, U., Souady, J., Hülsewig, M., Drmić-Hofman, I., Haier, J., Denz, A., Grützmann, R., Pilarsky, C., Senninger, N., Dreisewerd, K., Berkenkamp, S., Schmidt, M. A., Peter-Katalinic, J. & Müthing, J., 08.2008, In: MOL CANCER THER. 7, 8, p. 2464-75 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review