Will SNPs be useful predictors of normal tissue radiosensitivity in the future?
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Will SNPs be useful predictors of normal tissue radiosensitivity in the future? / Andreassen, Christian Nicolaj; Dikomey, Ekkehard; Parliament, Matthew; West, Catharine Mary Louise.
in: RADIOTHER ONCOL, Jahrgang 105, Nr. 3, 3, 2012, S. 283-288.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Will SNPs be useful predictors of normal tissue radiosensitivity in the future?
AU - Andreassen, Christian Nicolaj
AU - Dikomey, Ekkehard
AU - Parliament, Matthew
AU - West, Catharine Mary Louise
PY - 2012
Y1 - 2012
N2 - The ability to predict individual risk of radiation-induced normal tissue complications is a long sought goal in radiobiology. The last decade saw increasing interest in identifying associations between single nucleotide polymorphisms (SNPs) and normal tissue complication risk. Nevertheless, it remains controversial whether SNPs will be useful predictors of normal tissue radiosensitivity. This paper provides a summary of a scientific debate held at the 31st ESTRO conference in which four scientists argued in favor or against the motion that SNPs will be useful predictors of normal tissue radiosensitivity in the future.
AB - The ability to predict individual risk of radiation-induced normal tissue complications is a long sought goal in radiobiology. The last decade saw increasing interest in identifying associations between single nucleotide polymorphisms (SNPs) and normal tissue complication risk. Nevertheless, it remains controversial whether SNPs will be useful predictors of normal tissue radiosensitivity. This paper provides a summary of a scientific debate held at the 31st ESTRO conference in which four scientists argued in favor or against the motion that SNPs will be useful predictors of normal tissue radiosensitivity in the future.
KW - Humans
KW - Sensitivity and Specificity
KW - Predictive Value of Tests
KW - Meta-Analysis as Topic
KW - Risk
KW - Congresses as Topic
KW - DNA-Binding Proteins/genetics
KW - Cell Survival/genetics
KW - Polymorphism, Single Nucleotide
KW - Genetic Markers/genetics
KW - Radiation Tolerance/genetics
KW - Pharmacogenetics/trends
KW - Radiation Injuries/diagnosis/etiology/genetics
KW - Radiobiology/trends
KW - Humans
KW - Sensitivity and Specificity
KW - Predictive Value of Tests
KW - Meta-Analysis as Topic
KW - Risk
KW - Congresses as Topic
KW - DNA-Binding Proteins/genetics
KW - Cell Survival/genetics
KW - Polymorphism, Single Nucleotide
KW - Genetic Markers/genetics
KW - Radiation Tolerance/genetics
KW - Pharmacogenetics/trends
KW - Radiation Injuries/diagnosis/etiology/genetics
KW - Radiobiology/trends
M3 - SCORING: Journal article
VL - 105
SP - 283
EP - 288
JO - RADIOTHER ONCOL
JF - RADIOTHER ONCOL
SN - 0167-8140
IS - 3
M1 - 3
ER -