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What an epigenome remembers

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What an epigenome remembers. / Lange, Ulrike C; Schneider, Robert.

in: BIOESSAYS, Jahrgang 32, Nr. 8, 01.08.2010, S. 659-68.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Lange, UC & Schneider, R 2010, 'What an epigenome remembers', BIOESSAYS, Jg. 32, Nr. 8, S. 659-68. https://doi.org/10.1002/bies.201000030

APA

Lange, U. C., & Schneider, R. (2010). What an epigenome remembers. BIOESSAYS, 32(8), 659-68. https://doi.org/10.1002/bies.201000030

Vancouver

Lange UC, Schneider R. What an epigenome remembers. BIOESSAYS. 2010 Aug 1;32(8):659-68. https://doi.org/10.1002/bies.201000030

Bibtex

@article{9004d80b773c4590929217b415e0ad16,
title = "What an epigenome remembers",
abstract = "During mammalian development, maintenance of cell fate through mitotic divisions require faithful replication not only of the DNA but also of a particular epigenetic state. Germline cells have the capacity of erasing this epigenetic memory at crucial times during development, thereby resetting their epigenome. Certain marks, however, appear to escape this reprogramming, which allows their transmission to the offspring and potentially guarantees transgenerational epigenetic inheritance. Here we discuss the molecular requirements for faithful transmission of epigenetic information and our current knowledge about the transmission of epigenetic information through generations.",
keywords = "inheritance, DNA Methylation, Epigenetics, Histones",
author = "Lange, {Ulrike C} and Robert Schneider",
year = "2010",
month = aug,
day = "1",
doi = "10.1002/bies.201000030",
language = "English",
volume = "32",
pages = "659--68",
journal = "BIOESSAYS",
issn = "0265-9247",
publisher = "John Wiley and Sons Inc.",
number = "8",

}

RIS

TY - JOUR

T1 - What an epigenome remembers

AU - Lange, Ulrike C

AU - Schneider, Robert

PY - 2010/8/1

Y1 - 2010/8/1

N2 - During mammalian development, maintenance of cell fate through mitotic divisions require faithful replication not only of the DNA but also of a particular epigenetic state. Germline cells have the capacity of erasing this epigenetic memory at crucial times during development, thereby resetting their epigenome. Certain marks, however, appear to escape this reprogramming, which allows their transmission to the offspring and potentially guarantees transgenerational epigenetic inheritance. Here we discuss the molecular requirements for faithful transmission of epigenetic information and our current knowledge about the transmission of epigenetic information through generations.

AB - During mammalian development, maintenance of cell fate through mitotic divisions require faithful replication not only of the DNA but also of a particular epigenetic state. Germline cells have the capacity of erasing this epigenetic memory at crucial times during development, thereby resetting their epigenome. Certain marks, however, appear to escape this reprogramming, which allows their transmission to the offspring and potentially guarantees transgenerational epigenetic inheritance. Here we discuss the molecular requirements for faithful transmission of epigenetic information and our current knowledge about the transmission of epigenetic information through generations.

KW - inheritance

KW - DNA Methylation

KW - Epigenetics

KW - Histones

U2 - 10.1002/bies.201000030

DO - 10.1002/bies.201000030

M3 - SCORING: Journal article

C2 - 20658704

VL - 32

SP - 659

EP - 668

JO - BIOESSAYS

JF - BIOESSAYS

SN - 0265-9247

IS - 8

ER -