Vorzeitiger Abbruch randomisierter kontrollierter Studien: Vorteilsbedingter Therapieeffekt
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Vorzeitiger Abbruch randomisierter kontrollierter Studien: Vorteilsbedingter Therapieeffekt. / Kluth, L A; Rink, M; Ahyai, S A; Fisch, M; Shariat, S F; Dahm, P.
in: UROLOGE, Jahrgang 52, Nr. 8, 01.08.2013, S. 1080-3.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Vorzeitiger Abbruch randomisierter kontrollierter Studien: Vorteilsbedingter Therapieeffekt
AU - Kluth, L A
AU - Rink, M
AU - Ahyai, S A
AU - Fisch, M
AU - Shariat, S F
AU - Dahm, P
PY - 2013/8/1
Y1 - 2013/8/1
N2 - Randomized controlled trials (RCTs) stopped prematurely for beneficial therapy effects are becoming increasingly more prevalent in the urological literature and often receive great attention in the public and medical media. Urologists who practice evidence-based medicine should be aware of the potential bias and the different reasons why and how early termination of RCTs can and will affect the results. This review provides insights into the challenges clinical urologists face by interpreting the results of prematurely terminated RCTs.
AB - Randomized controlled trials (RCTs) stopped prematurely for beneficial therapy effects are becoming increasingly more prevalent in the urological literature and often receive great attention in the public and medical media. Urologists who practice evidence-based medicine should be aware of the potential bias and the different reasons why and how early termination of RCTs can and will affect the results. This review provides insights into the challenges clinical urologists face by interpreting the results of prematurely terminated RCTs.
KW - Bias (Epidemiology)
KW - Evidence-Based Medicine
KW - Humans
KW - Outcome Assessment (Health Care)
KW - Physicians
KW - Randomized Controlled Trials as Topic
U2 - 10.1007/s00120-013-3144-2
DO - 10.1007/s00120-013-3144-2
M3 - SCORING: Zeitschriftenaufsatz
C2 - 23712423
VL - 52
SP - 1080
EP - 1083
JO - UROLOGE
JF - UROLOGE
SN - 0340-2592
IS - 8
ER -