Ventral Striatum Connectivity During Reward Anticipation in Adolescent Smokers
Standard
Ventral Striatum Connectivity During Reward Anticipation in Adolescent Smokers. / Jollans, Lee; Zhipeng, Cao; Icke, Ilknur; Greene, Ciara; Kelly, Clare; Banaschewski, Tobias; Bokde, Arun L W; Bromberg, Uli; Büchel, Christian; Cattrell, Anna; Conrod, Patricia J; Desrivières, Sylvane; Flor, Herta; Frouin, Vincent; Gallinat, Jürgen; Garavan, Hugh; Gowland, Penny; Heinz, Andreas; Ittermann, Bernd; Martinot, Jean-Luc; Artiges, Eric; Nees, Frauke; Papadopoulos Orfanos, Dimitri; Paus, Tomáš; Smolka, Michael N; Walter, Henrik; Schumann, Gunter; Whelan, Robert.
in: DEV NEUROPSYCHOL, Jahrgang 41, Nr. 1-2, 14.04.2016, S. 6-21.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Ventral Striatum Connectivity During Reward Anticipation in Adolescent Smokers
AU - Jollans, Lee
AU - Zhipeng, Cao
AU - Icke, Ilknur
AU - Greene, Ciara
AU - Kelly, Clare
AU - Banaschewski, Tobias
AU - Bokde, Arun L W
AU - Bromberg, Uli
AU - Büchel, Christian
AU - Cattrell, Anna
AU - Conrod, Patricia J
AU - Desrivières, Sylvane
AU - Flor, Herta
AU - Frouin, Vincent
AU - Gallinat, Jürgen
AU - Garavan, Hugh
AU - Gowland, Penny
AU - Heinz, Andreas
AU - Ittermann, Bernd
AU - Martinot, Jean-Luc
AU - Artiges, Eric
AU - Nees, Frauke
AU - Papadopoulos Orfanos, Dimitri
AU - Paus, Tomáš
AU - Smolka, Michael N
AU - Walter, Henrik
AU - Schumann, Gunter
AU - Whelan, Robert
PY - 2016/4/14
Y1 - 2016/4/14
N2 - Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of adolescent smokers. Increased smoking frequency was associated with (1) increased connectivity with regions involved in saliency and valuation, including the orbitofrontal cortex and (2) reduced connectivity between the ventral striatum and regions associated with inhibition and risk aversion, including the right inferior frontal gyrus. These results demonstrate that functional connectivity during reward processing is relevant to adolescent addiction.
AB - Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of adolescent smokers. Increased smoking frequency was associated with (1) increased connectivity with regions involved in saliency and valuation, including the orbitofrontal cortex and (2) reduced connectivity between the ventral striatum and regions associated with inhibition and risk aversion, including the right inferior frontal gyrus. These results demonstrate that functional connectivity during reward processing is relevant to adolescent addiction.
U2 - 10.1080/87565641.2016.1164172
DO - 10.1080/87565641.2016.1164172
M3 - SCORING: Journal article
C2 - 27074029
VL - 41
SP - 6
EP - 21
JO - DEV NEUROPSYCHOL
JF - DEV NEUROPSYCHOL
SN - 8756-5641
IS - 1-2
ER -