Vascular occlusion sites determine differences in lesion growth from early apparent diffusion coefficient lesion to final infarct.

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Vascular occlusion sites determine differences in lesion growth from early apparent diffusion coefficient lesion to final infarct. / Fiehler, Jens; Knudsen, Karina; Thomalla, Götz; Goebell, Einar; Rosenkranz, Michael; Weiller, Cornelius; Röther, Joachim; Zeumer, Hermann; Kucinski, Thomas.

in: AM J NEURORADIOL, Jahrgang 26, Nr. 5, 5, 2005, S. 1056-1061.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{56dca21066164dc7aea46f93b850f5b5,
title = "Vascular occlusion sites determine differences in lesion growth from early apparent diffusion coefficient lesion to final infarct.",
abstract = "BACKGROUND AND PURPOSE: Occlusion of major cerebral arteries is the primary source of tissue damage in ischemic stroke and the target of thrombolytic therapy. We hypothesized that large infarcts in more proximal vascular occlusions correspond with substantially increased ischemic lesions shown on initial apparent diffusion coefficient (ADC) maps. METHODS: Initial ADC lesions in 120 patients with acute ischemic stroke were analyzed within 6 hours of stroke onset. Patients were categorized on the basis of vascular occlusion, as shown on MR angiography. Lesion volumes were determined by using manual delineation (ADC(man)) and a threshold method for ADC values (",
author = "Jens Fiehler and Karina Knudsen and G{\"o}tz Thomalla and Einar Goebell and Michael Rosenkranz and Cornelius Weiller and Joachim R{\"o}ther and Hermann Zeumer and Thomas Kucinski",
year = "2005",
language = "Deutsch",
volume = "26",
pages = "1056--1061",
journal = "AM J NEURORADIOL",
issn = "0195-6108",
publisher = "American Society of Neuroradiology",
number = "5",

}

RIS

TY - JOUR

T1 - Vascular occlusion sites determine differences in lesion growth from early apparent diffusion coefficient lesion to final infarct.

AU - Fiehler, Jens

AU - Knudsen, Karina

AU - Thomalla, Götz

AU - Goebell, Einar

AU - Rosenkranz, Michael

AU - Weiller, Cornelius

AU - Röther, Joachim

AU - Zeumer, Hermann

AU - Kucinski, Thomas

PY - 2005

Y1 - 2005

N2 - BACKGROUND AND PURPOSE: Occlusion of major cerebral arteries is the primary source of tissue damage in ischemic stroke and the target of thrombolytic therapy. We hypothesized that large infarcts in more proximal vascular occlusions correspond with substantially increased ischemic lesions shown on initial apparent diffusion coefficient (ADC) maps. METHODS: Initial ADC lesions in 120 patients with acute ischemic stroke were analyzed within 6 hours of stroke onset. Patients were categorized on the basis of vascular occlusion, as shown on MR angiography. Lesion volumes were determined by using manual delineation (ADC(man)) and a threshold method for ADC values (

AB - BACKGROUND AND PURPOSE: Occlusion of major cerebral arteries is the primary source of tissue damage in ischemic stroke and the target of thrombolytic therapy. We hypothesized that large infarcts in more proximal vascular occlusions correspond with substantially increased ischemic lesions shown on initial apparent diffusion coefficient (ADC) maps. METHODS: Initial ADC lesions in 120 patients with acute ischemic stroke were analyzed within 6 hours of stroke onset. Patients were categorized on the basis of vascular occlusion, as shown on MR angiography. Lesion volumes were determined by using manual delineation (ADC(man)) and a threshold method for ADC values (

M3 - SCORING: Zeitschriftenaufsatz

VL - 26

SP - 1056

EP - 1061

JO - AM J NEURORADIOL

JF - AM J NEURORADIOL

SN - 0195-6108

IS - 5

M1 - 5

ER -