Vaccine-induced immune thrombotic thrombocytopenia (VITT) after SARS-CoV-2 vaccination: Two cases from Germany with unusual presentation

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Vaccine-induced immune thrombotic thrombocytopenia (VITT) after SARS-CoV-2 vaccination: Two cases from Germany with unusual presentation. / Edmonds, Rhea; Schönborn, Linda; Habben, Sunke; Paparoupa, Maria; Greinacher, Andreas; Schuppert, Frank.

in: CLIN CASE REP, Jahrgang 11, Nr. 1, 01.2023, S. e6883.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungCase ReportForschungBegutachtung

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@article{201419707a49488b8dfb774705e1704d,
title = "Vaccine-induced immune thrombotic thrombocytopenia (VITT) after SARS-CoV-2 vaccination: Two cases from Germany with unusual presentation",
abstract = "Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare clinical condition that has emerged during the mass immunization against SARS-CoV-2. Reports indicate that VITT may also be induced by other vaccines, such as the human papillomavirus vaccine, or occur independently of vaccination. Its recognition requires a high index of suspicion, especially in patients presenting with thrombocytopenia and thrombosis several days after vaccination with an adenoviral vector-based vaccine against SARS-CoV-2. Bleeding manifestations do not exclude VITT, as initially assumed. It is of great importance to perform the appropriate diagnostic tests early in the course of the disease, as false-negative results may occur and many aspects of VITT are not fully understood. These two cases from Germany demonstrate unusual presentations of VITT.",
author = "Rhea Edmonds and Linda Sch{\"o}nborn and Sunke Habben and Maria Paparoupa and Andreas Greinacher and Frank Schuppert",
note = "{\textcopyright} 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.",
year = "2023",
month = jan,
doi = "10.1002/ccr3.6883",
language = "English",
volume = "11",
pages = "e6883",
journal = "CLIN CASE REP",
issn = "2050-0904",
publisher = "John Wiley and Sons Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - Vaccine-induced immune thrombotic thrombocytopenia (VITT) after SARS-CoV-2 vaccination: Two cases from Germany with unusual presentation

AU - Edmonds, Rhea

AU - Schönborn, Linda

AU - Habben, Sunke

AU - Paparoupa, Maria

AU - Greinacher, Andreas

AU - Schuppert, Frank

N1 - © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

PY - 2023/1

Y1 - 2023/1

N2 - Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare clinical condition that has emerged during the mass immunization against SARS-CoV-2. Reports indicate that VITT may also be induced by other vaccines, such as the human papillomavirus vaccine, or occur independently of vaccination. Its recognition requires a high index of suspicion, especially in patients presenting with thrombocytopenia and thrombosis several days after vaccination with an adenoviral vector-based vaccine against SARS-CoV-2. Bleeding manifestations do not exclude VITT, as initially assumed. It is of great importance to perform the appropriate diagnostic tests early in the course of the disease, as false-negative results may occur and many aspects of VITT are not fully understood. These two cases from Germany demonstrate unusual presentations of VITT.

AB - Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare clinical condition that has emerged during the mass immunization against SARS-CoV-2. Reports indicate that VITT may also be induced by other vaccines, such as the human papillomavirus vaccine, or occur independently of vaccination. Its recognition requires a high index of suspicion, especially in patients presenting with thrombocytopenia and thrombosis several days after vaccination with an adenoviral vector-based vaccine against SARS-CoV-2. Bleeding manifestations do not exclude VITT, as initially assumed. It is of great importance to perform the appropriate diagnostic tests early in the course of the disease, as false-negative results may occur and many aspects of VITT are not fully understood. These two cases from Germany demonstrate unusual presentations of VITT.

U2 - 10.1002/ccr3.6883

DO - 10.1002/ccr3.6883

M3 - Case report

C2 - 36698527

VL - 11

SP - e6883

JO - CLIN CASE REP

JF - CLIN CASE REP

SN - 2050-0904

IS - 1

ER -