Use of Novel Electrogram "Lumipoint" Algorithm to Detect Critical Isthmus and Abnormal Potentials for Ablation in Ventricular Tachycardia

Claire A Martin; Masateru Takigawa; Ruairidh Martin; Philippe Maury; Christian Meyer; Tom Wong; Rui Shi; Parag Gajendragadkar; Antonio Frontera; Ghassen Cheniti; Nathaniel Thompson; Takeshi Kitamura; Konstantinos Vlachos; Michael Wolf; Felix Bourier; Anna Lam; Josselin Duchâteau; Grégoire Massoullié; Thomas Pambrun; Arnaud Denis; Nicolas Derval; Mélèze Hocini; Michel Haïssaguerre; Pierre Jaïs; Frédéric Sacher

doi:10.1016/j.jacep.2019.01.016

Use of Novel Electrogram "Lumipoint" Algorithm to Detect Critical Isthmus and Abnormal Potentials for Ablation in Ventricular Tachycardia

Standard

Use of Novel Electrogram "Lumipoint" Algorithm to Detect Critical Isthmus and Abnormal Potentials for Ablation in Ventricular Tachycardia. / Martin, Claire A; Takigawa, Masateru; Martin, Ruairidh; Maury, Philippe; Meyer, Christian; Wong, Tom; Shi, Rui; Gajendragadkar, Parag; Frontera, Antonio; Cheniti, Ghassen; Thompson, Nathaniel; Kitamura, Takeshi; Vlachos, Konstantinos; Wolf, Michael; Bourier, Felix; Lam, Anna; Duchâteau, Josselin; Massoullié, Grégoire; Pambrun, Thomas; Denis, Arnaud; Derval, Nicolas; Hocini, Mélèze; Haïssaguerre, Michel; Jaïs, Pierre; Sacher, Frédéric.

in: JACC-CLIN ELECTROPHY, Jahrgang 5, Nr. 4, 04.2019, S. 470-479.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Martin, CA, Takigawa, M, Martin, R, Maury, P, Meyer, C, Wong, T, Shi, R, Gajendragadkar, P, Frontera, A, Cheniti, G, Thompson, N, Kitamura, T, Vlachos, K, Wolf, M, Bourier, F, Lam, A, Duchâteau, J, Massoullié, G, Pambrun, T, Denis, A, Derval, N, Hocini, M, Haïssaguerre, M, Jaïs, P & Sacher, F 2019, 'Use of Novel Electrogram "Lumipoint" Algorithm to Detect Critical Isthmus and Abnormal Potentials for Ablation in Ventricular Tachycardia', JACC-CLIN ELECTROPHY, Jg. 5, Nr. 4, S. 470-479. https://doi.org/10.1016/j.jacep.2019.01.016

APA

Martin, C. A., Takigawa, M., Martin, R., Maury, P., Meyer, C., Wong, T., Shi, R., Gajendragadkar, P., Frontera, A., Cheniti, G., Thompson, N., Kitamura, T., Vlachos, K., Wolf, M., Bourier, F., Lam, A., Duchâteau, J., Massoullié, G., Pambrun, T., ... Sacher, F. (2019). Use of Novel Electrogram "Lumipoint" Algorithm to Detect Critical Isthmus and Abnormal Potentials for Ablation in Ventricular Tachycardia. JACC-CLIN ELECTROPHY, 5(4), 470-479. https://doi.org/10.1016/j.jacep.2019.01.016

Vancouver

Martin CA, Takigawa M, Martin R, Maury P, Meyer C, Wong T et al. Use of Novel Electrogram "Lumipoint" Algorithm to Detect Critical Isthmus and Abnormal Potentials for Ablation in Ventricular Tachycardia. JACC-CLIN ELECTROPHY. 2019 Apr;5(4):470-479. https://doi.org/10.1016/j.jacep.2019.01.016

Bibtex

@article{dbb36baaa9b9459bb003bb4e5cc04123,

title = "Use of Novel Electrogram {"}Lumipoint{"} Algorithm to Detect Critical Isthmus and Abnormal Potentials for Ablation in Ventricular Tachycardia",

abstract = "OBJECTIVES: This study reports the use of a novel {"}Lumipoint{"} algorithm in ventricular tachycardia (VT) ablation.BACKGROUND: Automatic mapping systems aid rapid acquisition of activation maps. However, they may annotate farfield rather than nearfield signal in low voltage areas, making maps difficult to interpret. The Lumipoint algorithm analyzes the complete electrogram tracing and therefore includes nearfield signals in its analysis.METHODS: Twenty-two patients with ischemic cardiomyopathy and 5 with dilated cardiomyopathy underwent mapping using the ultra-high density Rhythmia system. Lumipoint algorithms were applied retrospectively.RESULTS: In all left ventricular substrate maps, changing the window of interest to the post-QRS phase automatically identified late potentials. In 25 of 27 left ventricular VT activation maps, a minimum spatial window of interest correctly identified the VT isthmus as seen by the manually annotated map, entrainment, and response to ablation. In 6 maps, the algorithm identified the isthmus where the standard automatically annotated map did not.CONCLUSIONS: The Lumipoint algorithm automatically highlights areas with electrograms having specific characteristics or timings. This can identify late and fractionated potentials and regions that exhibit discontinuous activation, as well as the isthmus of a VT circuit. These features may enhance human interpretation of the electrogram signals during a case, particularly where the circuit lies in partial scar with low amplitude nearfield signals and potentially allow a more targeted ablation strategy.",

keywords = "Aged, Algorithms, Catheter Ablation, Electrophysiologic Techniques, Cardiac/methods, Female, Heart Ventricles/physiopathology, Humans, Male, Middle Aged, Retrospective Studies, Tachycardia, Ventricular/diagnosis",

author = "Martin, {Claire A} and Masateru Takigawa and Ruairidh Martin and Philippe Maury and Christian Meyer and Tom Wong and Rui Shi and Parag Gajendragadkar and Antonio Frontera and Ghassen Cheniti and Nathaniel Thompson and Takeshi Kitamura and Konstantinos Vlachos and Michael Wolf and Felix Bourier and Anna Lam and Josselin Duch{\^a}teau and Gr{\'e}goire Massoulli{\'e} and Thomas Pambrun and Arnaud Denis and Nicolas Derval and M{\'e}l{\`e}ze Hocini and Michel Ha{\"i}ssaguerre and Pierre Ja{\"i}s and Fr{\'e}d{\'e}ric Sacher",

year = "2019",

month = apr,

doi = "10.1016/j.jacep.2019.01.016",

language = "English",

volume = "5",

pages = "470--479",

journal = "JACC-CLIN ELECTROPHY",

issn = "2405-500X",

publisher = "Elsevier USA",

number = "4",

}

RIS

TY - JOUR

T1 - Use of Novel Electrogram "Lumipoint" Algorithm to Detect Critical Isthmus and Abnormal Potentials for Ablation in Ventricular Tachycardia

AU - Martin, Claire A

AU - Takigawa, Masateru

AU - Martin, Ruairidh

AU - Maury, Philippe

AU - Meyer, Christian

AU - Wong, Tom

AU - Shi, Rui

AU - Gajendragadkar, Parag

AU - Frontera, Antonio

AU - Cheniti, Ghassen

AU - Thompson, Nathaniel

AU - Kitamura, Takeshi

AU - Vlachos, Konstantinos

AU - Wolf, Michael

AU - Bourier, Felix

AU - Lam, Anna

AU - Duchâteau, Josselin

AU - Massoullié, Grégoire

AU - Pambrun, Thomas

AU - Denis, Arnaud

AU - Derval, Nicolas

AU - Hocini, Mélèze

AU - Haïssaguerre, Michel

AU - Jaïs, Pierre

AU - Sacher, Frédéric

PY - 2019/4

Y1 - 2019/4

N2 - OBJECTIVES: This study reports the use of a novel "Lumipoint" algorithm in ventricular tachycardia (VT) ablation.BACKGROUND: Automatic mapping systems aid rapid acquisition of activation maps. However, they may annotate farfield rather than nearfield signal in low voltage areas, making maps difficult to interpret. The Lumipoint algorithm analyzes the complete electrogram tracing and therefore includes nearfield signals in its analysis.METHODS: Twenty-two patients with ischemic cardiomyopathy and 5 with dilated cardiomyopathy underwent mapping using the ultra-high density Rhythmia system. Lumipoint algorithms were applied retrospectively.RESULTS: In all left ventricular substrate maps, changing the window of interest to the post-QRS phase automatically identified late potentials. In 25 of 27 left ventricular VT activation maps, a minimum spatial window of interest correctly identified the VT isthmus as seen by the manually annotated map, entrainment, and response to ablation. In 6 maps, the algorithm identified the isthmus where the standard automatically annotated map did not.CONCLUSIONS: The Lumipoint algorithm automatically highlights areas with electrograms having specific characteristics or timings. This can identify late and fractionated potentials and regions that exhibit discontinuous activation, as well as the isthmus of a VT circuit. These features may enhance human interpretation of the electrogram signals during a case, particularly where the circuit lies in partial scar with low amplitude nearfield signals and potentially allow a more targeted ablation strategy.

AB - OBJECTIVES: This study reports the use of a novel "Lumipoint" algorithm in ventricular tachycardia (VT) ablation.BACKGROUND: Automatic mapping systems aid rapid acquisition of activation maps. However, they may annotate farfield rather than nearfield signal in low voltage areas, making maps difficult to interpret. The Lumipoint algorithm analyzes the complete electrogram tracing and therefore includes nearfield signals in its analysis.METHODS: Twenty-two patients with ischemic cardiomyopathy and 5 with dilated cardiomyopathy underwent mapping using the ultra-high density Rhythmia system. Lumipoint algorithms were applied retrospectively.RESULTS: In all left ventricular substrate maps, changing the window of interest to the post-QRS phase automatically identified late potentials. In 25 of 27 left ventricular VT activation maps, a minimum spatial window of interest correctly identified the VT isthmus as seen by the manually annotated map, entrainment, and response to ablation. In 6 maps, the algorithm identified the isthmus where the standard automatically annotated map did not.CONCLUSIONS: The Lumipoint algorithm automatically highlights areas with electrograms having specific characteristics or timings. This can identify late and fractionated potentials and regions that exhibit discontinuous activation, as well as the isthmus of a VT circuit. These features may enhance human interpretation of the electrogram signals during a case, particularly where the circuit lies in partial scar with low amplitude nearfield signals and potentially allow a more targeted ablation strategy.

KW - Aged

KW - Algorithms

KW - Catheter Ablation

KW - Electrophysiologic Techniques, Cardiac/methods

KW - Female

KW - Heart Ventricles/physiopathology

KW - Humans

KW - Male

KW - Middle Aged

KW - Retrospective Studies

KW - Tachycardia, Ventricular/diagnosis

U2 - 10.1016/j.jacep.2019.01.016

DO - 10.1016/j.jacep.2019.01.016

M3 - SCORING: Journal article

C2 - 31000101

VL - 5

SP - 470

EP - 479

JO - JACC-CLIN ELECTROPHY

JF - JACC-CLIN ELECTROPHY

SN - 2405-500X

IS - 4

ER -