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Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study

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Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study. / Haider, Dominik G; Lindner, Gregor; Wolzt, Michael; Leichtle, Alexander Benedikt; Fiedler, Georg-Martin; Sauter, Thomas C; Fuhrmann, Valentin; Exadaktylos, Aristomenis K.

in: J Negat Results Biomed, Jahrgang 15, Nr. 1, 2016, S. 1-4.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Haider, DG, Lindner, G, Wolzt, M, Leichtle, AB, Fiedler, G-M, Sauter, TC, Fuhrmann, V & Exadaktylos, AK 2016, 'Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study', J Negat Results Biomed, Jg. 15, Nr. 1, S. 1-4. https://doi.org/10.1186/s12952-016-0044-1

APA

Haider, D. G., Lindner, G., Wolzt, M., Leichtle, A. B., Fiedler, G-M., Sauter, T. C., Fuhrmann, V., & Exadaktylos, A. K. (2016). Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study. J Negat Results Biomed, 15(1), 1-4. https://doi.org/10.1186/s12952-016-0044-1

Vancouver

Haider DG, Lindner G, Wolzt M, Leichtle AB, Fiedler G-M, Sauter TC et al. Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study. J Negat Results Biomed. 2016;15(1):1-4. https://doi.org/10.1186/s12952-016-0044-1

Bibtex

@article{67bfb8e6ab5243a2bacf2195c313d2b7,
title = "Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study",
abstract = "BACKGROUND: Patients with diuretic therapy are at risk for drug-induced adverse reactions. It is unknown if presence of diuretic therapy at hospital emergency room admission is associated with mortality.METHODS: In this cross sectional analysis, all emergency room patients 2010 and 2011 at the Inselspital Bern, Switzerland were included. A multivariable logistic regression model was performed to assess the association between pre-existing diuretic medication and 28 day mortality.RESULTS: Twenty-two thousand two hundred thirty-nine subjects were included in the analysis. A total of 8.5 %, 2.5 %, and 0.4 % of patients used one, two, or three or more diuretics. In univariate analysis spironolactone, torasemide and chlortalidone use were associated with 28 day mortality (all p < 0.05). In a multivariate cox regression model no association with mortality was detectable (p > 0.05). No difference existed between patients with or without diuretic therapy (P > 0.05). Age and creatinine were independent risk factors for mortaliy (both p < 0.05).CONCLUSION: Use of diuretics is not associated with mortality in an unselected cohort of patients presenting in an emergency room.",
author = "Haider, {Dominik G} and Gregor Lindner and Michael Wolzt and Leichtle, {Alexander Benedikt} and Georg-Martin Fiedler and Sauter, {Thomas C} and Valentin Fuhrmann and Exadaktylos, {Aristomenis K}",
year = "2016",
doi = "10.1186/s12952-016-0044-1",
language = "English",
volume = "15",
pages = "1--4",
journal = "J Negat Results Biomed",
issn = "1477-5751",
publisher = "Springer International Publishing",
number = "1",

}

RIS

TY - JOUR

T1 - Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study

AU - Haider, Dominik G

AU - Lindner, Gregor

AU - Wolzt, Michael

AU - Leichtle, Alexander Benedikt

AU - Fiedler, Georg-Martin

AU - Sauter, Thomas C

AU - Fuhrmann, Valentin

AU - Exadaktylos, Aristomenis K

PY - 2016

Y1 - 2016

N2 - BACKGROUND: Patients with diuretic therapy are at risk for drug-induced adverse reactions. It is unknown if presence of diuretic therapy at hospital emergency room admission is associated with mortality.METHODS: In this cross sectional analysis, all emergency room patients 2010 and 2011 at the Inselspital Bern, Switzerland were included. A multivariable logistic regression model was performed to assess the association between pre-existing diuretic medication and 28 day mortality.RESULTS: Twenty-two thousand two hundred thirty-nine subjects were included in the analysis. A total of 8.5 %, 2.5 %, and 0.4 % of patients used one, two, or three or more diuretics. In univariate analysis spironolactone, torasemide and chlortalidone use were associated with 28 day mortality (all p < 0.05). In a multivariate cox regression model no association with mortality was detectable (p > 0.05). No difference existed between patients with or without diuretic therapy (P > 0.05). Age and creatinine were independent risk factors for mortaliy (both p < 0.05).CONCLUSION: Use of diuretics is not associated with mortality in an unselected cohort of patients presenting in an emergency room.

AB - BACKGROUND: Patients with diuretic therapy are at risk for drug-induced adverse reactions. It is unknown if presence of diuretic therapy at hospital emergency room admission is associated with mortality.METHODS: In this cross sectional analysis, all emergency room patients 2010 and 2011 at the Inselspital Bern, Switzerland were included. A multivariable logistic regression model was performed to assess the association between pre-existing diuretic medication and 28 day mortality.RESULTS: Twenty-two thousand two hundred thirty-nine subjects were included in the analysis. A total of 8.5 %, 2.5 %, and 0.4 % of patients used one, two, or three or more diuretics. In univariate analysis spironolactone, torasemide and chlortalidone use were associated with 28 day mortality (all p < 0.05). In a multivariate cox regression model no association with mortality was detectable (p > 0.05). No difference existed between patients with or without diuretic therapy (P > 0.05). Age and creatinine were independent risk factors for mortaliy (both p < 0.05).CONCLUSION: Use of diuretics is not associated with mortality in an unselected cohort of patients presenting in an emergency room.

U2 - 10.1186/s12952-016-0044-1

DO - 10.1186/s12952-016-0044-1

M3 - SCORING: Journal article

C2 - 26832747

VL - 15

SP - 1

EP - 4

JO - J Negat Results Biomed

JF - J Negat Results Biomed

SN - 1477-5751

IS - 1

ER -