Update Breast Cancer 2020 Part 4 - Advanced Breast Cancer
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Update Breast Cancer 2020 Part 4 - Advanced Breast Cancer. / Tesch, Hans; Müller, Volkmar; Wöckel, Achim; Ettl, Johannes; Belleville, Erik; Schütz, Florian; Hartkopf, Andreas; Thill, Marc; Huober, Jens; Fasching, Peter A; Kolberg, Hans-Christian; Schulmeyer, Carla E; Welslau, Manfred; Overkamp, Friedrich; Fehm, Tanja N; Lux, Michael P; Schneeweiss, Andreas; Lüftner, Diana; Janni, Wolfgang.
in: GEBURTSH FRAUENHEILK, Jahrgang 80, Nr. 11, 11.2020, S. 1115-1122.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Update Breast Cancer 2020 Part 4 - Advanced Breast Cancer
AU - Tesch, Hans
AU - Müller, Volkmar
AU - Wöckel, Achim
AU - Ettl, Johannes
AU - Belleville, Erik
AU - Schütz, Florian
AU - Hartkopf, Andreas
AU - Thill, Marc
AU - Huober, Jens
AU - Fasching, Peter A
AU - Kolberg, Hans-Christian
AU - Schulmeyer, Carla E
AU - Welslau, Manfred
AU - Overkamp, Friedrich
AU - Fehm, Tanja N
AU - Lux, Michael P
AU - Schneeweiss, Andreas
AU - Lüftner, Diana
AU - Janni, Wolfgang
N1 - The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
PY - 2020/11
Y1 - 2020/11
N2 - Substances with good effectiveness that intervene in specific signalling pathways have been used increasingly in recent years in the treatment of patients with advanced breast cancer, and new therapies and approaches have now been added, which actually relate to quite specific changes, such as the treatment of patients with HR+/HER2 tumours with a PIK3CA mutation. The treatment of patients with a BRCA1 or BRCA2 mutation has also been improved by the introduction of PARP inhibitors. Attempts are now being made increasingly to extend treatment indications based on molecular patterns, to identify other patients who could benefit from a treatment and to integrate the newly established treatment methods in existing therapy sequences. This review articles summarises the latest information in this connection.
AB - Substances with good effectiveness that intervene in specific signalling pathways have been used increasingly in recent years in the treatment of patients with advanced breast cancer, and new therapies and approaches have now been added, which actually relate to quite specific changes, such as the treatment of patients with HR+/HER2 tumours with a PIK3CA mutation. The treatment of patients with a BRCA1 or BRCA2 mutation has also been improved by the introduction of PARP inhibitors. Attempts are now being made increasingly to extend treatment indications based on molecular patterns, to identify other patients who could benefit from a treatment and to integrate the newly established treatment methods in existing therapy sequences. This review articles summarises the latest information in this connection.
U2 - 10.1055/a-1270-7481
DO - 10.1055/a-1270-7481
M3 - SCORING: Journal article
C2 - 33173239
VL - 80
SP - 1115
EP - 1122
JO - GEBURTSH FRAUENHEILK
JF - GEBURTSH FRAUENHEILK
SN - 0016-5751
IS - 11
ER -