Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections

Sylvanus Okogbenin; Cyril Erameh; Joseph Okoeguale; Osahogie Edeawe; Esele Ekuaze; Kelly Iraoyah; John Agho; Mirjam Groger; Benno Kreuels; Lisa Oestereich; Femi O Babatunde; Peter Akhideno; Stephan Günther; Michael Ramharter; Till Omansen

doi:10.3201/eid2810.220625

Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections

Sylvanus Okogbenin
Cyril Erameh
Joseph Okoeguale
Osahogie Edeawe
Esele Ekuaze
Kelly Iraoyah
John Agho
Mirjam Groger
Benno Kreuels
Lisa Oestereich
Femi O Babatunde
Peter Akhideno
Stephan Günther
Michael Ramharter
Till Omansen

Beteiligte Einrichtungen

I. Medizinische Klinik und Poliklinik

Abstract

Lassa fever is a viral hemorrhagic fever treated with supportive care and the broad-spectrum antiviral drug ribavirin. The pathophysiology, especially the role of hyperinflammation, of this disease is unknown. We report successful remission of complicated Lassa fever in 2 patients in Nigeria who received the antiinflammatory agent dexamethasone and standard ribavirin.

Bibliografische Daten

Originalsprache	Englisch
ISSN	1080-6040
DOIs	https://doi.org/10.3201/eid2810.220625
Status	Veröffentlicht - 10.2022

PubMed	36148915