PortalPublikationenTransvenous lead extraction in patients with systemic cardia...

Transvenous lead extraction in patients with systemic cardiac device-related infection-Procedural outcome and risk prediction: A GALLERY subgroup analysis

Standard

Transvenous lead extraction in patients with systemic cardiac device-related infection-Procedural outcome and risk prediction: A GALLERY subgroup analysis. / Chung, Da-Un; Burger, Heiko; Kaiser, Lukas; Osswald, Brigitte; Bärsch, Volker; Nägele, Herbert; Knaut, Michael; Reichenspurner, Hermann; Gessler, Nele; Willems, Stephan; Butter, Christian; Pecha, Simon; Hakmi, Samer; GALLERY investigators.

in: HEART RHYTHM, Jahrgang 20, Nr. 2, 02.2023, S. 181-189.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Chung, D-U, Burger, H, Kaiser, L, Osswald, B, Bärsch, V, Nägele, H, Knaut, M, Reichenspurner, H, Gessler, N, Willems, S, Butter, C, Pecha, S, Hakmi, S & GALLERY investigators 2023, 'Transvenous lead extraction in patients with systemic cardiac device-related infection-Procedural outcome and risk prediction: A GALLERY subgroup analysis', HEART RHYTHM, Jg. 20, Nr. 2, S. 181-189. https://doi.org/10.1016/j.hrthm.2022.10.004

APA

Chung, D-U., Burger, H., Kaiser, L., Osswald, B., Bärsch, V., Nägele, H., Knaut, M., Reichenspurner, H., Gessler, N., Willems, S., Butter, C., Pecha, S., Hakmi, S., & GALLERY investigators (2023). Transvenous lead extraction in patients with systemic cardiac device-related infection-Procedural outcome and risk prediction: A GALLERY subgroup analysis. HEART RHYTHM, 20(2), 181-189. https://doi.org/10.1016/j.hrthm.2022.10.004

Vancouver

Chung D-U, Burger H, Kaiser L, Osswald B, Bärsch V, Nägele H et al. Transvenous lead extraction in patients with systemic cardiac device-related infection-Procedural outcome and risk prediction: A GALLERY subgroup analysis. HEART RHYTHM. 2023 Feb;20(2):181-189. https://doi.org/10.1016/j.hrthm.2022.10.004

Bibtex

@article{94d7f920923a4fe5a7dd006c457d88cc,
title = "Transvenous lead extraction in patients with systemic cardiac device-related infection-Procedural outcome and risk prediction: A GALLERY subgroup analysis",
abstract = "BACKGROUND: Transvenous lead extraction (TLE) has evolved as one of the most crucial treatment options for patients with cardiac device-related systemic infection (CDRSI).OBJECTIVE: The aim of this study was to characterize the procedural outcome and risk factors of patients with CDRSI undergoing TLE.METHODS: A subgroup analysis of patients with CDRSI of the GALLERY (GermAn Laser Lead Extraction RegistrY) database was performed. Predictors for complications, procedural failure, and all-cause mortality were evaluated.RESULTS: A total of 722 patients (28.6%) in the GALLERY had {"}systemic infection{"} as extraction indication. Patients with CDRSI were older (70.1 ± 12.2 years vs 67.3 ± 14.3 years; P < .001) and had more comorbidities than patients with local infections or noninfectious extraction indications. There were no differences in complete procedural success (90.6% vs 91.7%; P = .328) or major complications (2.5% vs 1.9%; P = .416) but increased procedure-related (1.4% vs 0.3%; P = .003) and all-cause in-hospital mortality (11.1% vs 0.6%; P < .001) for patients with CDRSI. Multivariate analyses revealed lead age ≥10 years as a predictor for procedural complications (odds ratio [OR] 3.23; 95% confidence interval [CI] 1.58-6.60; P = .001). Lead age ≥10 years (OR 2.57; 95% CI 1.03-6.46; P = .04) was also a predictor for procedural failure. We identified left ventricular ejection fraction <30% (OR 1.70; 95% CI 1.00-2.99; P = .049), age ≥75 years (OR 2.1; 95% CI 1.27-3.48; P = .004), chronic kidney disease (OR 1.92; 95% CI 1.17-3.14; P = .01), and overall procedural complications (OR 5.15; 95% CI 2.44-10.84; P < .001) as predictors for all-cause mortality.CONCLUSION: Patients with CDRSI undergoing TLE demonstrate an increased rate of all-cause in-hospital, as well as procedure-related mortality, despite having comparable procedural success rates. Given these data, it seems paramount to develop preventive strategies to detect and treat CDRSI in its earliest stages.",
author = "Da-Un Chung and Heiko Burger and Lukas Kaiser and Brigitte Osswald and Volker B{\"a}rsch and Herbert N{\"a}gele and Michael Knaut and Hermann Reichenspurner and Nele Gessler and Stephan Willems and Christian Butter and Simon Pecha and Samer Hakmi and {GALLERY investigators}",
note = "Copyright {\textcopyright} 2022 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.",
year = "2023",
month = feb,
doi = "10.1016/j.hrthm.2022.10.004",
language = "English",
volume = "20",
pages = "181--189",
journal = "HEART RHYTHM",
issn = "1547-5271",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - Transvenous lead extraction in patients with systemic cardiac device-related infection-Procedural outcome and risk prediction: A GALLERY subgroup analysis

AU - Chung, Da-Un

AU - Burger, Heiko

AU - Kaiser, Lukas

AU - Osswald, Brigitte

AU - Bärsch, Volker

AU - Nägele, Herbert

AU - Knaut, Michael

AU - Reichenspurner, Hermann

AU - Gessler, Nele

AU - Willems, Stephan

AU - Butter, Christian

AU - Pecha, Simon

AU - Hakmi, Samer

AU - GALLERY investigators

N1 - Copyright © 2022 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

PY - 2023/2

Y1 - 2023/2

N2 - BACKGROUND: Transvenous lead extraction (TLE) has evolved as one of the most crucial treatment options for patients with cardiac device-related systemic infection (CDRSI).OBJECTIVE: The aim of this study was to characterize the procedural outcome and risk factors of patients with CDRSI undergoing TLE.METHODS: A subgroup analysis of patients with CDRSI of the GALLERY (GermAn Laser Lead Extraction RegistrY) database was performed. Predictors for complications, procedural failure, and all-cause mortality were evaluated.RESULTS: A total of 722 patients (28.6%) in the GALLERY had "systemic infection" as extraction indication. Patients with CDRSI were older (70.1 ± 12.2 years vs 67.3 ± 14.3 years; P < .001) and had more comorbidities than patients with local infections or noninfectious extraction indications. There were no differences in complete procedural success (90.6% vs 91.7%; P = .328) or major complications (2.5% vs 1.9%; P = .416) but increased procedure-related (1.4% vs 0.3%; P = .003) and all-cause in-hospital mortality (11.1% vs 0.6%; P < .001) for patients with CDRSI. Multivariate analyses revealed lead age ≥10 years as a predictor for procedural complications (odds ratio [OR] 3.23; 95% confidence interval [CI] 1.58-6.60; P = .001). Lead age ≥10 years (OR 2.57; 95% CI 1.03-6.46; P = .04) was also a predictor for procedural failure. We identified left ventricular ejection fraction <30% (OR 1.70; 95% CI 1.00-2.99; P = .049), age ≥75 years (OR 2.1; 95% CI 1.27-3.48; P = .004), chronic kidney disease (OR 1.92; 95% CI 1.17-3.14; P = .01), and overall procedural complications (OR 5.15; 95% CI 2.44-10.84; P < .001) as predictors for all-cause mortality.CONCLUSION: Patients with CDRSI undergoing TLE demonstrate an increased rate of all-cause in-hospital, as well as procedure-related mortality, despite having comparable procedural success rates. Given these data, it seems paramount to develop preventive strategies to detect and treat CDRSI in its earliest stages.

AB - BACKGROUND: Transvenous lead extraction (TLE) has evolved as one of the most crucial treatment options for patients with cardiac device-related systemic infection (CDRSI).OBJECTIVE: The aim of this study was to characterize the procedural outcome and risk factors of patients with CDRSI undergoing TLE.METHODS: A subgroup analysis of patients with CDRSI of the GALLERY (GermAn Laser Lead Extraction RegistrY) database was performed. Predictors for complications, procedural failure, and all-cause mortality were evaluated.RESULTS: A total of 722 patients (28.6%) in the GALLERY had "systemic infection" as extraction indication. Patients with CDRSI were older (70.1 ± 12.2 years vs 67.3 ± 14.3 years; P < .001) and had more comorbidities than patients with local infections or noninfectious extraction indications. There were no differences in complete procedural success (90.6% vs 91.7%; P = .328) or major complications (2.5% vs 1.9%; P = .416) but increased procedure-related (1.4% vs 0.3%; P = .003) and all-cause in-hospital mortality (11.1% vs 0.6%; P < .001) for patients with CDRSI. Multivariate analyses revealed lead age ≥10 years as a predictor for procedural complications (odds ratio [OR] 3.23; 95% confidence interval [CI] 1.58-6.60; P = .001). Lead age ≥10 years (OR 2.57; 95% CI 1.03-6.46; P = .04) was also a predictor for procedural failure. We identified left ventricular ejection fraction <30% (OR 1.70; 95% CI 1.00-2.99; P = .049), age ≥75 years (OR 2.1; 95% CI 1.27-3.48; P = .004), chronic kidney disease (OR 1.92; 95% CI 1.17-3.14; P = .01), and overall procedural complications (OR 5.15; 95% CI 2.44-10.84; P < .001) as predictors for all-cause mortality.CONCLUSION: Patients with CDRSI undergoing TLE demonstrate an increased rate of all-cause in-hospital, as well as procedure-related mortality, despite having comparable procedural success rates. Given these data, it seems paramount to develop preventive strategies to detect and treat CDRSI in its earliest stages.

U2 - 10.1016/j.hrthm.2022.10.004

DO - 10.1016/j.hrthm.2022.10.004

M3 - SCORING: Journal article

C2 - 36240993

VL - 20

SP - 181

EP - 189

JO - HEART RHYTHM

JF - HEART RHYTHM

SN - 1547-5271

IS - 2

ER -