Transcatheter Tricuspid Valve Intervention in Patients with Previous Left Valve Surgery
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Transcatheter Tricuspid Valve Intervention in Patients with Previous Left Valve Surgery. / Muntané-Carol, Guillem; Taramasso, Maurizio; Miura, Mizuki; Gavazzoni, Mara; Pozzoli, Alberto; Alessandrini, Hannes; Latib, Azeem; Attinger-Toller, Adrian; Biasco, Luigi; Braun, Daniel; Brochet, Eric; Connelly, Kim A; Sievert, Horst; Denti, Paolo; Lubos, Edith; Ludwig, Sebastian; Kalbacher, Daniel; Estevez-Loureiro, Rodrigo; Fam, Neil; Frerker, Christian; Ho, Edwin; Juliard, Jean-Michel; Kaple, Ryan; Kodali, Susheel; Kreidel, Felix; Harr, Claudia; Lauten, Alexander; Lurz, Julia; Kresoja, Karl-Patrik; Monivas, Vanessa; Mehr, Michael; Nazif, Tamim; Nickening, Georg; Pedrazzini, Giovanni; Philippon, François; Praz, Fabien; Puri, Rishi; Schäfer, Ulrich; Schofer, Joachim; Tang, Gilbert H L; Khattab, Ahmed A; Andreas, Martin; Russo, Marco; Thiele, Holger; Unterhuber, Matthias; Himbert, Dominique; Urena, Marina; Stephan von Bardeleben, Ralph; Webb, John G; Weber, Marcel; Winkel, Mirjam; Zuber, Michel; Hausleiter, Jörg; Lurz, Philipp; Maisano, Francesco; Leon, Martin B; Hahn, Rebecca T; Rodés-Cabau, Josep.
in: CAN J CARDIOL, Jahrgang 37, Nr. 7, 07.2021, S. 1094-1102.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Transcatheter Tricuspid Valve Intervention in Patients with Previous Left Valve Surgery
AU - Muntané-Carol, Guillem
AU - Taramasso, Maurizio
AU - Miura, Mizuki
AU - Gavazzoni, Mara
AU - Pozzoli, Alberto
AU - Alessandrini, Hannes
AU - Latib, Azeem
AU - Attinger-Toller, Adrian
AU - Biasco, Luigi
AU - Braun, Daniel
AU - Brochet, Eric
AU - Connelly, Kim A
AU - Sievert, Horst
AU - Denti, Paolo
AU - Lubos, Edith
AU - Ludwig, Sebastian
AU - Kalbacher, Daniel
AU - Estevez-Loureiro, Rodrigo
AU - Fam, Neil
AU - Frerker, Christian
AU - Ho, Edwin
AU - Juliard, Jean-Michel
AU - Kaple, Ryan
AU - Kodali, Susheel
AU - Kreidel, Felix
AU - Harr, Claudia
AU - Lauten, Alexander
AU - Lurz, Julia
AU - Kresoja, Karl-Patrik
AU - Monivas, Vanessa
AU - Mehr, Michael
AU - Nazif, Tamim
AU - Nickening, Georg
AU - Pedrazzini, Giovanni
AU - Philippon, François
AU - Praz, Fabien
AU - Puri, Rishi
AU - Schäfer, Ulrich
AU - Schofer, Joachim
AU - Tang, Gilbert H L
AU - Khattab, Ahmed A
AU - Andreas, Martin
AU - Russo, Marco
AU - Thiele, Holger
AU - Unterhuber, Matthias
AU - Himbert, Dominique
AU - Urena, Marina
AU - Stephan von Bardeleben, Ralph
AU - Webb, John G
AU - Weber, Marcel
AU - Winkel, Mirjam
AU - Zuber, Michel
AU - Hausleiter, Jörg
AU - Lurz, Philipp
AU - Maisano, Francesco
AU - Leon, Martin B
AU - Hahn, Rebecca T
AU - Rodés-Cabau, Josep
N1 - Copyright © 2021. Published by Elsevier Inc.
PY - 2021/7
Y1 - 2021/7
N2 - BACKGROUND: Scarce data exist on patients with previous left valve surgery (PLVS) undergoing transcatheter tricuspid valve intervention (TTVI). This study sought to investigate the procedural and early outcomes in patients with PLVS undergoing TTVI.METHODS: This was a subanalysis of the multicenter TriValve registry including 462 patients, 82 (18%) with PLVS. Data were analyzed according to the presence of PLVS in the overall cohort and in a propensity score-matched population including 51 and 115 patients with and without PLVS, respectively.RESULTS: Patients with PLVS were younger (72 ± 10 vs 78 ± 9 years; p < 0.01) and more frequently female (67.1% vs 53.2%; P = 0.02). Similar rates of procedural success (PLVS 80.5%; no-PLVS 82.1%; P = 0.73), and 30-day mortality (PLVS 2.4%, no-PLVS 3.4%; P = 0.99) were observed. After matching, there were no significant differences in both all-cause rehospitalisation (PLVS 21.1%, no-PLVS 26.5%; P = 0.60) and all-cause mortality (PLVS 9.8%, no-PLVS 6.7%; P = 0.58). At last follow-up (median 6 [interquartile range 1-12] months after the procedure), most patients (81.8%) in the PLVS group were in NYHA functional class I-II (P = 0.12 vs no-PLVS group), and TR grade was ≤ 2 in 82.6% of patients (P = 0.096 vs no-PVLS group). A poorer right ventricular function and previous heart failure hospitalization determined increased risks of procedural failure and poorer outcomes at follow-up, respectively.CONCLUSIONS: In patients with PLVS, TTVI was associated with high rates of procedural success and low early mortality. However, about one-third of patients required rehospitalisation or died at midterm follow-up. These results would support TTVI as a reasonable alternative to redo surgery in patients with PLVS and suggest the importance of earlier treatment to improve clinical outcomes.
AB - BACKGROUND: Scarce data exist on patients with previous left valve surgery (PLVS) undergoing transcatheter tricuspid valve intervention (TTVI). This study sought to investigate the procedural and early outcomes in patients with PLVS undergoing TTVI.METHODS: This was a subanalysis of the multicenter TriValve registry including 462 patients, 82 (18%) with PLVS. Data were analyzed according to the presence of PLVS in the overall cohort and in a propensity score-matched population including 51 and 115 patients with and without PLVS, respectively.RESULTS: Patients with PLVS were younger (72 ± 10 vs 78 ± 9 years; p < 0.01) and more frequently female (67.1% vs 53.2%; P = 0.02). Similar rates of procedural success (PLVS 80.5%; no-PLVS 82.1%; P = 0.73), and 30-day mortality (PLVS 2.4%, no-PLVS 3.4%; P = 0.99) were observed. After matching, there were no significant differences in both all-cause rehospitalisation (PLVS 21.1%, no-PLVS 26.5%; P = 0.60) and all-cause mortality (PLVS 9.8%, no-PLVS 6.7%; P = 0.58). At last follow-up (median 6 [interquartile range 1-12] months after the procedure), most patients (81.8%) in the PLVS group were in NYHA functional class I-II (P = 0.12 vs no-PLVS group), and TR grade was ≤ 2 in 82.6% of patients (P = 0.096 vs no-PVLS group). A poorer right ventricular function and previous heart failure hospitalization determined increased risks of procedural failure and poorer outcomes at follow-up, respectively.CONCLUSIONS: In patients with PLVS, TTVI was associated with high rates of procedural success and low early mortality. However, about one-third of patients required rehospitalisation or died at midterm follow-up. These results would support TTVI as a reasonable alternative to redo surgery in patients with PLVS and suggest the importance of earlier treatment to improve clinical outcomes.
U2 - 10.1016/j.cjca.2021.02.010
DO - 10.1016/j.cjca.2021.02.010
M3 - SCORING: Journal article
C2 - 33617978
VL - 37
SP - 1094
EP - 1102
JO - CAN J CARDIOL
JF - CAN J CARDIOL
SN - 0828-282X
IS - 7
ER -