Toxic proteins from European mistletoe (Viscum album L.): increase of intracellular IL-4 but decrease of IFN-gamma in apoptotic cells.

  • G M Stein
  • Uwe Pfüller
  • M Schietzel
  • A Büssing

Abstract

Mistletoe lectins (ML), the major biologically active components of mistletoe extracts, which are used for adjuvant cancer therapy, induce apoptosis in lymphocytes and tumor cells. In addition, ML at toxic concentrations induce the release of cytokines, but it remains unclear as to whether dying or activated cells are responsible.

Bibliografische Daten

OriginalspracheDeutsch
Aufsatznummer3
ISSN0250-7005
StatusVeröffentlicht - 2000
pubmed 10928090