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Topical long-term therapy of psoriasis with vitamin D₃ analogues, corticosteroids and their two compound formulations: position paper on evidence and use in daily practice

Standard

Topical long-term therapy of psoriasis with vitamin D₃ analogues, corticosteroids and their two compound formulations: position paper on evidence and use in daily practice. / Augustin, Matthias; Mrowietz, Ulrich; Bonnekoh, Bernd; Rosenbach, Thomas; Thaçi, Diamant; Reusch, Michael; Ardabili, Michael; Reich, Kristian.

in: J DTSCH DERMATOL GES, Jahrgang 12, Nr. 8, 01.08.2014, S. 667-682.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Augustin, M, Mrowietz, U, Bonnekoh, B, Rosenbach, T, Thaçi, D, Reusch, M, Ardabili, M & Reich, K 2014, 'Topical long-term therapy of psoriasis with vitamin D₃ analogues, corticosteroids and their two compound formulations: position paper on evidence and use in daily practice', J DTSCH DERMATOL GES, Jg. 12, Nr. 8, S. 667-682. https://doi.org/10.1111/ddg.12396

APA

Augustin, M., Mrowietz, U., Bonnekoh, B., Rosenbach, T., Thaçi, D., Reusch, M., Ardabili, M., & Reich, K. (2014). Topical long-term therapy of psoriasis with vitamin D₃ analogues, corticosteroids and their two compound formulations: position paper on evidence and use in daily practice. J DTSCH DERMATOL GES, 12(8), 667-682. https://doi.org/10.1111/ddg.12396

Vancouver

Augustin M, Mrowietz U, Bonnekoh B, Rosenbach T, Thaçi D, Reusch M et al. Topical long-term therapy of psoriasis with vitamin D₃ analogues, corticosteroids and their two compound formulations: position paper on evidence and use in daily practice. J DTSCH DERMATOL GES. 2014 Aug 1;12(8):667-682. https://doi.org/10.1111/ddg.12396

Bibtex

@article{570bf02d494d46cbad9bb656c5534506,
title = "Topical long-term therapy of psoriasis with vitamin D₃ analogues, corticosteroids and their two compound formulations: position paper on evidence and use in daily practice",
abstract = "BACKGROUND: Current data from daily practice show that vitamin D₃ analogues, corticosteroids and their fixed combination products are used heterogeneously for topical long-term treatment of psoriasis.AIM: To evaluate scientific evidence about topical long-term therapy with vitamin D3 analogues, corticosteroids and their two-compound-products in psoriasis vulgaris and scalp psoriasis and to develop daily practice recommendations.METHODS: Systematic literature review via PubMed and Embase and informal expert consensus.RESULTS: The search strategy identified 21 relevant clinical trials. Best evidence regarding topical long term treatment was available for the two-compound-formulation containing calcipotriene and betamethasone. In a comparative trial in psoriasis vulgaris the two-compound-formulation showed superior tolerability and cost effectiveness compared to monotherapy. In scalp psoriasis the two-compound-gel was superior compared to calcipotriene monotherapy. Standardized and simplified treatment application modes resulted in a better clinical outcome comparing to on-demand therapies.DAILY PRACTICE RECOMMENDATIONS: Patients should be proactively involved in the choice of treatment, formulation and mode of application. Besides long-term treatment with the two-compound-formulation other treatment regimens including calcipotriene monotherapy can also be considered. Due to a favorable risk-benefit ratio in maintenance trials and due to better cost-effectiveness the application of two-compound-products once or twice a week after initial therapy is recommended.",
author = "Matthias Augustin and Ulrich Mrowietz and Bernd Bonnekoh and Thomas Rosenbach and Diamant Tha{\c c}i and Michael Reusch and Michael Ardabili and Kristian Reich",
note = "{\textcopyright} 2014 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.",
year = "2014",
month = aug,
day = "1",
doi = "10.1111/ddg.12396",
language = "English",
volume = "12",
pages = "667--682",
journal = "J DTSCH DERMATOL GES",
issn = "1610-0379",
publisher = "Wiley-Blackwell",
number = "8",

}

RIS

TY - JOUR

T1 - Topical long-term therapy of psoriasis with vitamin D₃ analogues, corticosteroids and their two compound formulations: position paper on evidence and use in daily practice

AU - Augustin, Matthias

AU - Mrowietz, Ulrich

AU - Bonnekoh, Bernd

AU - Rosenbach, Thomas

AU - Thaçi, Diamant

AU - Reusch, Michael

AU - Ardabili, Michael

AU - Reich, Kristian

N1 - © 2014 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

PY - 2014/8/1

Y1 - 2014/8/1

N2 - BACKGROUND: Current data from daily practice show that vitamin D₃ analogues, corticosteroids and their fixed combination products are used heterogeneously for topical long-term treatment of psoriasis.AIM: To evaluate scientific evidence about topical long-term therapy with vitamin D3 analogues, corticosteroids and their two-compound-products in psoriasis vulgaris and scalp psoriasis and to develop daily practice recommendations.METHODS: Systematic literature review via PubMed and Embase and informal expert consensus.RESULTS: The search strategy identified 21 relevant clinical trials. Best evidence regarding topical long term treatment was available for the two-compound-formulation containing calcipotriene and betamethasone. In a comparative trial in psoriasis vulgaris the two-compound-formulation showed superior tolerability and cost effectiveness compared to monotherapy. In scalp psoriasis the two-compound-gel was superior compared to calcipotriene monotherapy. Standardized and simplified treatment application modes resulted in a better clinical outcome comparing to on-demand therapies.DAILY PRACTICE RECOMMENDATIONS: Patients should be proactively involved in the choice of treatment, formulation and mode of application. Besides long-term treatment with the two-compound-formulation other treatment regimens including calcipotriene monotherapy can also be considered. Due to a favorable risk-benefit ratio in maintenance trials and due to better cost-effectiveness the application of two-compound-products once or twice a week after initial therapy is recommended.

AB - BACKGROUND: Current data from daily practice show that vitamin D₃ analogues, corticosteroids and their fixed combination products are used heterogeneously for topical long-term treatment of psoriasis.AIM: To evaluate scientific evidence about topical long-term therapy with vitamin D3 analogues, corticosteroids and their two-compound-products in psoriasis vulgaris and scalp psoriasis and to develop daily practice recommendations.METHODS: Systematic literature review via PubMed and Embase and informal expert consensus.RESULTS: The search strategy identified 21 relevant clinical trials. Best evidence regarding topical long term treatment was available for the two-compound-formulation containing calcipotriene and betamethasone. In a comparative trial in psoriasis vulgaris the two-compound-formulation showed superior tolerability and cost effectiveness compared to monotherapy. In scalp psoriasis the two-compound-gel was superior compared to calcipotriene monotherapy. Standardized and simplified treatment application modes resulted in a better clinical outcome comparing to on-demand therapies.DAILY PRACTICE RECOMMENDATIONS: Patients should be proactively involved in the choice of treatment, formulation and mode of application. Besides long-term treatment with the two-compound-formulation other treatment regimens including calcipotriene monotherapy can also be considered. Due to a favorable risk-benefit ratio in maintenance trials and due to better cost-effectiveness the application of two-compound-products once or twice a week after initial therapy is recommended.

U2 - 10.1111/ddg.12396

DO - 10.1111/ddg.12396

M3 - SCORING: Journal article

C2 - 25039309

VL - 12

SP - 667

EP - 682

JO - J DTSCH DERMATOL GES

JF - J DTSCH DERMATOL GES

SN - 1610-0379

IS - 8

ER -