Time period from onset of pain to hospital admission and patients' awareness in acute pancreatitis
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Time period from onset of pain to hospital admission and patients' awareness in acute pancreatitis. / Phillip, Veit; Schuster, Tibor; Hagemes, Frank; Lorenz, Sandra; Matheis, Ulrike; Preinfalk, Sigrid; Lippl, Florian; Saugel, Bernd; Schmid, Roland M; Huber, Wolfgang.
in: PANCREAS, Jahrgang 42, Nr. 4, 01.05.2013, S. 647-54.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Time period from onset of pain to hospital admission and patients' awareness in acute pancreatitis
AU - Phillip, Veit
AU - Schuster, Tibor
AU - Hagemes, Frank
AU - Lorenz, Sandra
AU - Matheis, Ulrike
AU - Preinfalk, Sigrid
AU - Lippl, Florian
AU - Saugel, Bernd
AU - Schmid, Roland M
AU - Huber, Wolfgang
PY - 2013/5/1
Y1 - 2013/5/1
N2 - OBJECTIVES: This study aimed to explore the period between onset of pain and hospital-admission (pain-to-admission time) in patients with acute pancreatitis (AP), to investigate the prognostic value and associated factors of this time, and to ascertain the knowledge about the pancreas in these patients.METHODS: An analysis of a prospective multicenter study was done, which included 188 patients with AP.RESULTS: Median pain-to-admission time was 27 hours (interquartile range, 6.0-72.0). Median pain-to-admission time was significantly shorter in intensive care unit (ICU) patients (10 hours) compared to non-ICU patients (36 hours) (P = 0.045). Short pain-to-admission time was associated with high pain level. Median pain level (0, no pain; 10, maximal pain) was 8.0 (interquartile range, 7.0-10.0). Older age correlated with lower pain level (r = -0.26; P = 0.002). Multiple logistic regression analysis including the admission values for serum lipase and C-reactive protein and the corresponding interactions to the pain-to-admission time showed substantial discriminative ability regarding ICU admission (concordance index, 0.706; P = 0.006). 86% (112/130) knew that they have a pancreas, 72% (81/112) of these patients knew that AP exists, and 56% (45/81) recognized that AP is potentially fatal.CONCLUSIONS: Knowledge about AP in hospitalized AP patients is poor. Serum lipase and C-reactive protein in dependency of the pain-to-admission time might be a suitable predictor for severity of AP.
AB - OBJECTIVES: This study aimed to explore the period between onset of pain and hospital-admission (pain-to-admission time) in patients with acute pancreatitis (AP), to investigate the prognostic value and associated factors of this time, and to ascertain the knowledge about the pancreas in these patients.METHODS: An analysis of a prospective multicenter study was done, which included 188 patients with AP.RESULTS: Median pain-to-admission time was 27 hours (interquartile range, 6.0-72.0). Median pain-to-admission time was significantly shorter in intensive care unit (ICU) patients (10 hours) compared to non-ICU patients (36 hours) (P = 0.045). Short pain-to-admission time was associated with high pain level. Median pain level (0, no pain; 10, maximal pain) was 8.0 (interquartile range, 7.0-10.0). Older age correlated with lower pain level (r = -0.26; P = 0.002). Multiple logistic regression analysis including the admission values for serum lipase and C-reactive protein and the corresponding interactions to the pain-to-admission time showed substantial discriminative ability regarding ICU admission (concordance index, 0.706; P = 0.006). 86% (112/130) knew that they have a pancreas, 72% (81/112) of these patients knew that AP exists, and 56% (45/81) recognized that AP is potentially fatal.CONCLUSIONS: Knowledge about AP in hospitalized AP patients is poor. Serum lipase and C-reactive protein in dependency of the pain-to-admission time might be a suitable predictor for severity of AP.
KW - Adult
KW - Aged
KW - C-Reactive Protein
KW - Female
KW - Health Knowledge, Attitudes, Practice
KW - Humans
KW - Intensive Care Units
KW - Lipase
KW - Logistic Models
KW - Male
KW - Middle Aged
KW - Pain
KW - Pancreatitis
KW - Patient Admission
KW - Prognosis
KW - Prospective Studies
KW - Time Factors
U2 - 10.1097/MPA.0b013e3182714565
DO - 10.1097/MPA.0b013e3182714565
M3 - SCORING: Journal article
C2 - 23303202
VL - 42
SP - 647
EP - 654
JO - PANCREAS
JF - PANCREAS
SN - 0885-3177
IS - 4
ER -