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Thirty years of cornea cultivation: long-term experience in a single eye bank.

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Thirty years of cornea cultivation: long-term experience in a single eye bank. / Linke, Stephan J; Eddy, Mau-Thek; Bednarz, Jürgen; Fricke, Otto H; Wulff, Birgit; Schröder, Ann Sophie; Hassenstein, Andrea; Klemm, Maren; Püschel, Klaus; Richard, Gisbert; Hellwinkel, Olaf J C.

in: ACTA OPHTHALMOL, Jahrgang 91, Nr. 6, 6, 2013, S. 571-578.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Linke, SJ, Eddy, M-T, Bednarz, J, Fricke, OH, Wulff, B, Schröder, AS, Hassenstein, A, Klemm, M, Püschel, K, Richard, G & Hellwinkel, OJC 2013, 'Thirty years of cornea cultivation: long-term experience in a single eye bank.', ACTA OPHTHALMOL, Jg. 91, Nr. 6, 6, S. 571-578. https://doi.org/10.1111/j.1755-3768.2012.02471.x

APA

Linke, S. J., Eddy, M-T., Bednarz, J., Fricke, O. H., Wulff, B., Schröder, A. S., Hassenstein, A., Klemm, M., Püschel, K., Richard, G., & Hellwinkel, O. J. C. (2013). Thirty years of cornea cultivation: long-term experience in a single eye bank. ACTA OPHTHALMOL, 91(6), 571-578. [6]. https://doi.org/10.1111/j.1755-3768.2012.02471.x

Vancouver

Linke SJ, Eddy M-T, Bednarz J, Fricke OH, Wulff B, Schröder AS et al. Thirty years of cornea cultivation: long-term experience in a single eye bank. ACTA OPHTHALMOL. 2013;91(6):571-578. 6. https://doi.org/10.1111/j.1755-3768.2012.02471.x

Bibtex

@article{5cb0e2f629f4405686270f85e8a5450c,
title = "Thirty years of cornea cultivation: long-term experience in a single eye bank.",
abstract = "PURPOSE: To evaluate donor demographics, trends in donor tissue procurement and tissue storage over a long period.METHODS: A retrospective, longitudinal, descriptive analysis was undertaken of data from the Hamburg Eye Bank Data Base (HEB-DB) that had been collected between 1981 and 2010. Data on 54 parameters of cornea donors [including clinical history, age, death cause, gender and death-to-explantation interval (DEI)] and of cultivated corneas (endothelial quality and development in culture, cultivation period, microbiological contamination) were retrieved. These data were analysed statistically, focusing on the historical development of the eye bank.RESULTS: At the time of retrieval (June 2010), the HEB-DB contained data on 10 943 corneas (5503 donors). Most donors were men (65%) and had died from cardiopulmonary (n = 801)/cerebral (n = 261) failure or as the result of a polytraumatic accident/suicide (n = 602). Within these years, donor age, DEI and storage time increased. The percentage of stored corneas suitable for transplantation displayed a variable but increasing trend; in 2007, almost 75% of the stored corneas were transplanted. Between 1995 and June 2010, the median microbiological contamination rate was 5.3%. A change in the procurement procedure from enucleation to corneoscleral explantation in 2008 led to a briefly increased contamination rate.CONCLUSION:   Donor demographic data run parallel to the general demographic development. Our analysis indicates a dynamic development of the eye bank over the last 30 years and emphasizes the need for an active quality management in coping with the challenges of modern eye banking.",
keywords = "Adult, Age Distribution, Aged, Aged, 80 and over, Cause of Death, Cell Count, Cornea, Corneal Transplantation, Databases, Factual, Eye Banks, Female, Follow-Up Studies, Germany, Humans, Male, Middle Aged, Organ Culture Techniques, Organ Preservation, Retrospective Studies, Tissue Donors, Tissue and Organ Procurement, Young Adult",
author = "Linke, {Stephan J} and Mau-Thek Eddy and J{\"u}rgen Bednarz and Fricke, {Otto H} and Birgit Wulff and Schr{\"o}der, {Ann Sophie} and Andrea Hassenstein and Maren Klemm and Klaus P{\"u}schel and Gisbert Richard and Hellwinkel, {Olaf J C}",
note = "{\textcopyright} 2012 The Authors. Acta Ophthalmologica {\textcopyright} 2012 Acta Ophthalmologica Scandinavica Foundation.",
year = "2013",
doi = "10.1111/j.1755-3768.2012.02471.x",
language = "English",
volume = "91",
pages = "571--578",
journal = "ACTA OPHTHALMOL",
issn = "1755-375X",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - Thirty years of cornea cultivation: long-term experience in a single eye bank.

AU - Linke, Stephan J

AU - Eddy, Mau-Thek

AU - Bednarz, Jürgen

AU - Fricke, Otto H

AU - Wulff, Birgit

AU - Schröder, Ann Sophie

AU - Hassenstein, Andrea

AU - Klemm, Maren

AU - Püschel, Klaus

AU - Richard, Gisbert

AU - Hellwinkel, Olaf J C

N1 - © 2012 The Authors. Acta Ophthalmologica © 2012 Acta Ophthalmologica Scandinavica Foundation.

PY - 2013

Y1 - 2013

N2 - PURPOSE: To evaluate donor demographics, trends in donor tissue procurement and tissue storage over a long period.METHODS: A retrospective, longitudinal, descriptive analysis was undertaken of data from the Hamburg Eye Bank Data Base (HEB-DB) that had been collected between 1981 and 2010. Data on 54 parameters of cornea donors [including clinical history, age, death cause, gender and death-to-explantation interval (DEI)] and of cultivated corneas (endothelial quality and development in culture, cultivation period, microbiological contamination) were retrieved. These data were analysed statistically, focusing on the historical development of the eye bank.RESULTS: At the time of retrieval (June 2010), the HEB-DB contained data on 10 943 corneas (5503 donors). Most donors were men (65%) and had died from cardiopulmonary (n = 801)/cerebral (n = 261) failure or as the result of a polytraumatic accident/suicide (n = 602). Within these years, donor age, DEI and storage time increased. The percentage of stored corneas suitable for transplantation displayed a variable but increasing trend; in 2007, almost 75% of the stored corneas were transplanted. Between 1995 and June 2010, the median microbiological contamination rate was 5.3%. A change in the procurement procedure from enucleation to corneoscleral explantation in 2008 led to a briefly increased contamination rate.CONCLUSION:   Donor demographic data run parallel to the general demographic development. Our analysis indicates a dynamic development of the eye bank over the last 30 years and emphasizes the need for an active quality management in coping with the challenges of modern eye banking.

AB - PURPOSE: To evaluate donor demographics, trends in donor tissue procurement and tissue storage over a long period.METHODS: A retrospective, longitudinal, descriptive analysis was undertaken of data from the Hamburg Eye Bank Data Base (HEB-DB) that had been collected between 1981 and 2010. Data on 54 parameters of cornea donors [including clinical history, age, death cause, gender and death-to-explantation interval (DEI)] and of cultivated corneas (endothelial quality and development in culture, cultivation period, microbiological contamination) were retrieved. These data were analysed statistically, focusing on the historical development of the eye bank.RESULTS: At the time of retrieval (June 2010), the HEB-DB contained data on 10 943 corneas (5503 donors). Most donors were men (65%) and had died from cardiopulmonary (n = 801)/cerebral (n = 261) failure or as the result of a polytraumatic accident/suicide (n = 602). Within these years, donor age, DEI and storage time increased. The percentage of stored corneas suitable for transplantation displayed a variable but increasing trend; in 2007, almost 75% of the stored corneas were transplanted. Between 1995 and June 2010, the median microbiological contamination rate was 5.3%. A change in the procurement procedure from enucleation to corneoscleral explantation in 2008 led to a briefly increased contamination rate.CONCLUSION:   Donor demographic data run parallel to the general demographic development. Our analysis indicates a dynamic development of the eye bank over the last 30 years and emphasizes the need for an active quality management in coping with the challenges of modern eye banking.

KW - Adult

KW - Age Distribution

KW - Aged

KW - Aged, 80 and over

KW - Cause of Death

KW - Cell Count

KW - Cornea

KW - Corneal Transplantation

KW - Databases, Factual

KW - Eye Banks

KW - Female

KW - Follow-Up Studies

KW - Germany

KW - Humans

KW - Male

KW - Middle Aged

KW - Organ Culture Techniques

KW - Organ Preservation

KW - Retrospective Studies

KW - Tissue Donors

KW - Tissue and Organ Procurement

KW - Young Adult

U2 - 10.1111/j.1755-3768.2012.02471.x

DO - 10.1111/j.1755-3768.2012.02471.x

M3 - SCORING: Journal article

C2 - 22863151

VL - 91

SP - 571

EP - 578

JO - ACTA OPHTHALMOL

JF - ACTA OPHTHALMOL

SN - 1755-375X

IS - 6

M1 - 6

ER -