Therapie der Rezidiv- und Fernmetastasen bei Plattenepithelkarzinomen des Kopf- und Halsbereichs: Highlights des ASCO-Meetings 2013
Beteiligte Einrichtungen
Abstract
In many cases squamous cell carcinoma of the head and neck is already in an advanced stage when initially diagnosed. Despite definitive treatment, loco-regional recurrences and metastases are common and patients ultimately require systemic treatment. Epidermal growth factor receptor (EGFR) inhibitors have proven to significantly prolong survival and have therefore become the first line treatment in recurrent and metastatic squamous cell carcinoma of the head and neck in addition to platinum and 5-FU treatment. Good results have also been reported for EGFR inhibitors in cases where platinum-based treatment has failed. Further strategies, such as salvage surgery, platinum-based chemotherapy, targeted therapy, chemoradiation and reirradiation are currently under investigation to reduce toxicity and improve survival and health-related quality of life.
Bibliografische Daten
Titel in Übersetzung | Therapy of recurrent and metastatic squamous cell carcinoma of the head and neck: highlights of the ASCO Meeting 2013 |
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Originalsprache | Deutsch |
ISSN | 0017-6192 |
DOIs | |
Status | Veröffentlicht - 01.11.2013 |
Anmerkungen des Dekanats
Leitthema, Zusammenfassung des ASCO 2013, Kongress-Nachschau
PubMed | 24221219 |
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