Therapie der pulmonal arteriellen Hypertonie
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Therapie der pulmonal arteriellen Hypertonie. / Klose, H; Harbaum, L; Oqueka, T; Simon, M; Grünig, E.
in: PNEUMOLOGIE, Jahrgang 69, Nr. 8, 08.2015, S. 483-93; quiz 494-5.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung
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TY - JOUR
T1 - Therapie der pulmonal arteriellen Hypertonie
AU - Klose, H
AU - Harbaum, L
AU - Oqueka, T
AU - Simon, M
AU - Grünig, E
N1 - © Georg Thieme Verlag KG Stuttgart · New York.
PY - 2015/8
Y1 - 2015/8
N2 - Pulmonary hypertension (PH) is classified into five distinct groups according to the fifth world conference in Nice 2013. Pulmonary arterial hypertension (PAH) comprises idiopathic PAH, hereditary PAH, drug-induced and associated PAH. Right heart catheterization is essential for the diagnosis of PH and should precede initiation of a targeted PAH therapy. Besides general measures and supportive therapy, four different classes of targeted drugs have been approved for the treatment of PAH. Combination therapy, either sequential or initial (up-front), is increasingly gaining recognition. Risk stratification and treatment goals have been defined to guide therapeutic decisions. However, cure is still far from reach and lung transplantation is an important treatment option for patients with end-stage disease under optimal supportive and targeted drug therapy.
AB - Pulmonary hypertension (PH) is classified into five distinct groups according to the fifth world conference in Nice 2013. Pulmonary arterial hypertension (PAH) comprises idiopathic PAH, hereditary PAH, drug-induced and associated PAH. Right heart catheterization is essential for the diagnosis of PH and should precede initiation of a targeted PAH therapy. Besides general measures and supportive therapy, four different classes of targeted drugs have been approved for the treatment of PAH. Combination therapy, either sequential or initial (up-front), is increasingly gaining recognition. Risk stratification and treatment goals have been defined to guide therapeutic decisions. However, cure is still far from reach and lung transplantation is an important treatment option for patients with end-stage disease under optimal supportive and targeted drug therapy.
U2 - 10.1055/s-0034-1392103
DO - 10.1055/s-0034-1392103
M3 - SCORING: Zeitschriftenaufsatz
C2 - 26220551
VL - 69
SP - 483-93; quiz 494-5
JO - PNEUMOLOGIE
JF - PNEUMOLOGIE
SN - 0934-8387
IS - 8
ER -