Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer.
Beteiligte Einrichtungen
Abstract
Activation of the non-receptor tyrosine kinase focal adhesion kinase (FAK) has been implicated in progression of multiple mesenchymal and epithelial malignant tumors. FAK plays an important role in regulation of proliferation, migration and apoptosis of neoplastic cells.
Bibliografische Daten
| Originalsprache | Deutsch |
|---|---|
| Aufsatznummer | 6 |
| ISSN | 1354-3784 |
| Status | Veröffentlicht - 2010 |
| pubmed | 20465362 |
|---|
