The Use of TissuGlu® Surgical Adhesive for Mastectomy With or Without Lymphonodectomy
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The Use of TissuGlu® Surgical Adhesive for Mastectomy With or Without Lymphonodectomy. / Ohlinger, Ralf; Gieron, Leonie; Rutkowski, Rico; Kohlmann, Thomas; Zygmunt, Marek; Unger, Julia.
in: IN VIVO, Jahrgang 32, Nr. 3, 27.04.2018, S. 625-631.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - The Use of TissuGlu® Surgical Adhesive for Mastectomy With or Without Lymphonodectomy
AU - Ohlinger, Ralf
AU - Gieron, Leonie
AU - Rutkowski, Rico
AU - Kohlmann, Thomas
AU - Zygmunt, Marek
AU - Unger, Julia
N1 - Copyright© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
PY - 2018/4/27
Y1 - 2018/4/27
N2 - BACKGROUND/AIM: Using drains after breast surgery is a preventive, but invasive measure to reduce seroma formation. A polyurethane-based tissue adhesive (TissuGlu®) might facilitate drainage-free wound healing after mastectomy in a non-invasive manner.PATIENTS AND METHODS: Retrospectively, data from 84 patients (42 receiving TissuGlu®, 42 receiving a drainage) who underwent mastectomy, were collected (90 days postoperative follow-up). Study endpoints were defined as the number of fluid-related postoperative clinical interventions, cumulative volume of postoperative wound fluid, duration of hospitalization and postoperative complications.RESULTS: In the entirety of postoperative interventions, no significant difference could be demonstrated (p=0.298). The drainage arm showed significantly less seroma aspirations (p=0.024) and complications (p=0.012). A significantly reduced length of hospitalization (p<0.001) and less cumulative wound secretion volume (p<0.001) appeared in the TissuGlu® group.CONCLUSION: The polyurethane-based tissue adhesive is a less invasive alternative to drain use in mastectomy.
AB - BACKGROUND/AIM: Using drains after breast surgery is a preventive, but invasive measure to reduce seroma formation. A polyurethane-based tissue adhesive (TissuGlu®) might facilitate drainage-free wound healing after mastectomy in a non-invasive manner.PATIENTS AND METHODS: Retrospectively, data from 84 patients (42 receiving TissuGlu®, 42 receiving a drainage) who underwent mastectomy, were collected (90 days postoperative follow-up). Study endpoints were defined as the number of fluid-related postoperative clinical interventions, cumulative volume of postoperative wound fluid, duration of hospitalization and postoperative complications.RESULTS: In the entirety of postoperative interventions, no significant difference could be demonstrated (p=0.298). The drainage arm showed significantly less seroma aspirations (p=0.024) and complications (p=0.012). A significantly reduced length of hospitalization (p<0.001) and less cumulative wound secretion volume (p<0.001) appeared in the TissuGlu® group.CONCLUSION: The polyurethane-based tissue adhesive is a less invasive alternative to drain use in mastectomy.
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Breast Neoplasms/pathology
KW - Drainage
KW - Female
KW - Follow-Up Studies
KW - Hospitalization
KW - Humans
KW - Lymph Node Excision
KW - Lymph Nodes/pathology
KW - Mastectomy/adverse effects
KW - Middle Aged
KW - Retrospective Studies
KW - Tissue Adhesives/therapeutic use
KW - Treatment Outcome
U2 - 10.21873/invivo.11284
DO - 10.21873/invivo.11284
M3 - SCORING: Journal article
C2 - 29695569
VL - 32
SP - 625
EP - 631
JO - IN VIVO
JF - IN VIVO
SN - 0258-851X
IS - 3
ER -
