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The Urethral Perfusion Index During Off-Pump Coronary Artery Bypass Surgery: An Observational Study

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The Urethral Perfusion Index During Off-Pump Coronary Artery Bypass Surgery: An Observational Study. / Flick, Moritz; Rosenau, Lorenz; Sadtler, Hannah; Kouz, Karim; Krause, Linda; Joosten, Alexandre; Schulte-Uentrop, Leonie; Saugel, Bernd Christopher.

in: J CARDIOTHOR VASC AN, Jahrgang 38, Nr. 2, 02.2024, S. 417-422.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Flick, M, Rosenau, L, Sadtler, H, Kouz, K, Krause, L, Joosten, A, Schulte-Uentrop, L & Saugel, BC 2024, 'The Urethral Perfusion Index During Off-Pump Coronary Artery Bypass Surgery: An Observational Study', J CARDIOTHOR VASC AN, Jg. 38, Nr. 2, S. 417-422. https://doi.org/10.1053/j.jvca.2023.09.015

APA

Flick, M., Rosenau, L., Sadtler, H., Kouz, K., Krause, L., Joosten, A., Schulte-Uentrop, L., & Saugel, B. C. (2024). The Urethral Perfusion Index During Off-Pump Coronary Artery Bypass Surgery: An Observational Study. J CARDIOTHOR VASC AN, 38(2), 417-422. https://doi.org/10.1053/j.jvca.2023.09.015

Vancouver

Flick M, Rosenau L, Sadtler H, Kouz K, Krause L, Joosten A et al. The Urethral Perfusion Index During Off-Pump Coronary Artery Bypass Surgery: An Observational Study. J CARDIOTHOR VASC AN. 2024 Feb;38(2):417-422. https://doi.org/10.1053/j.jvca.2023.09.015

Bibtex

@article{f96b0c152c5d42c6a7a8a6790763a5a7,
title = "The Urethral Perfusion Index During Off-Pump Coronary Artery Bypass Surgery: An Observational Study",
abstract = "OBJECTIVES: The IKORUS system (Vygon, {\'E}couen, France) allows continuous monitoring of the urethral perfusion index (uPI) using a photoplethysmographic sensor mounted near the base of the balloon of a dedicated urinary catheter. We aimed to test the hypothesis that the uPI decreases during off-pump coronary artery bypass (OPCAB) surgery and to investigate the relationship between the uPI and macrocirculatory variables.DESIGN: Prospective observational study.SETTING: University Medical Center Hamburg-Eppendorf, Hamburg, Germany.PARTICIPANTS: Twenty patients having OPCAB surgery.INTERVENTIONS: None.MEASUREMENTS AND MAIN RESULTS: The primary endpoint was changes in the uPI during OPCAB surgery. We additionally investigated associations between the uPI and cardiac output, mean arterial pressure, heart rate, and point-of-care variables. Twenty patients with 24,137 uPI measurements were included. Overall, there was a high interindividual variability in the uPI. Compared with the preparation phase (during which the median [interquartile range] uPI was 7.7 [5.6-12.0]), the uPI decreased by 14% (95% CI 13%-15%) during the bypass grafting phase, by 35% (95% CI 34%-36%) during the cardiac positioning phase, and by 7% (95% CI 6%-9%) during hemostasis. There was no clinically important association between uPI and either cardiac output, mean arterial pressure, or heart rate.CONCLUSIONS: The uPI decreases during OPCAB surgery, specifically during the cardiac positioning phase. There was no clinically important association between uPI and either cardiac output, mean arterial pressure, or heart rate. It, therefore, remains to be determined whether intraoperative uPI decreases are clinically important, reflect alterations in intra-abdominal tissue perfusion that are not reflected by systemic macrohemodynamics, and can help clinicians guide therapeutic interventions.",
author = "Moritz Flick and Lorenz Rosenau and Hannah Sadtler and Karim Kouz and Linda Krause and Alexandre Joosten and Leonie Schulte-Uentrop and Saugel, {Bernd Christopher}",
year = "2024",
month = feb,
doi = "10.1053/j.jvca.2023.09.015",
language = "English",
volume = "38",
pages = "417--422",
journal = "J CARDIOTHOR VASC AN",
issn = "1053-0770",
publisher = "W.B. Saunders Ltd",
number = "2",

}

RIS

TY - JOUR

T1 - The Urethral Perfusion Index During Off-Pump Coronary Artery Bypass Surgery: An Observational Study

AU - Flick, Moritz

AU - Rosenau, Lorenz

AU - Sadtler, Hannah

AU - Kouz, Karim

AU - Krause, Linda

AU - Joosten, Alexandre

AU - Schulte-Uentrop, Leonie

AU - Saugel, Bernd Christopher

PY - 2024/2

Y1 - 2024/2

N2 - OBJECTIVES: The IKORUS system (Vygon, Écouen, France) allows continuous monitoring of the urethral perfusion index (uPI) using a photoplethysmographic sensor mounted near the base of the balloon of a dedicated urinary catheter. We aimed to test the hypothesis that the uPI decreases during off-pump coronary artery bypass (OPCAB) surgery and to investigate the relationship between the uPI and macrocirculatory variables.DESIGN: Prospective observational study.SETTING: University Medical Center Hamburg-Eppendorf, Hamburg, Germany.PARTICIPANTS: Twenty patients having OPCAB surgery.INTERVENTIONS: None.MEASUREMENTS AND MAIN RESULTS: The primary endpoint was changes in the uPI during OPCAB surgery. We additionally investigated associations between the uPI and cardiac output, mean arterial pressure, heart rate, and point-of-care variables. Twenty patients with 24,137 uPI measurements were included. Overall, there was a high interindividual variability in the uPI. Compared with the preparation phase (during which the median [interquartile range] uPI was 7.7 [5.6-12.0]), the uPI decreased by 14% (95% CI 13%-15%) during the bypass grafting phase, by 35% (95% CI 34%-36%) during the cardiac positioning phase, and by 7% (95% CI 6%-9%) during hemostasis. There was no clinically important association between uPI and either cardiac output, mean arterial pressure, or heart rate.CONCLUSIONS: The uPI decreases during OPCAB surgery, specifically during the cardiac positioning phase. There was no clinically important association between uPI and either cardiac output, mean arterial pressure, or heart rate. It, therefore, remains to be determined whether intraoperative uPI decreases are clinically important, reflect alterations in intra-abdominal tissue perfusion that are not reflected by systemic macrohemodynamics, and can help clinicians guide therapeutic interventions.

AB - OBJECTIVES: The IKORUS system (Vygon, Écouen, France) allows continuous monitoring of the urethral perfusion index (uPI) using a photoplethysmographic sensor mounted near the base of the balloon of a dedicated urinary catheter. We aimed to test the hypothesis that the uPI decreases during off-pump coronary artery bypass (OPCAB) surgery and to investigate the relationship between the uPI and macrocirculatory variables.DESIGN: Prospective observational study.SETTING: University Medical Center Hamburg-Eppendorf, Hamburg, Germany.PARTICIPANTS: Twenty patients having OPCAB surgery.INTERVENTIONS: None.MEASUREMENTS AND MAIN RESULTS: The primary endpoint was changes in the uPI during OPCAB surgery. We additionally investigated associations between the uPI and cardiac output, mean arterial pressure, heart rate, and point-of-care variables. Twenty patients with 24,137 uPI measurements were included. Overall, there was a high interindividual variability in the uPI. Compared with the preparation phase (during which the median [interquartile range] uPI was 7.7 [5.6-12.0]), the uPI decreased by 14% (95% CI 13%-15%) during the bypass grafting phase, by 35% (95% CI 34%-36%) during the cardiac positioning phase, and by 7% (95% CI 6%-9%) during hemostasis. There was no clinically important association between uPI and either cardiac output, mean arterial pressure, or heart rate.CONCLUSIONS: The uPI decreases during OPCAB surgery, specifically during the cardiac positioning phase. There was no clinically important association between uPI and either cardiac output, mean arterial pressure, or heart rate. It, therefore, remains to be determined whether intraoperative uPI decreases are clinically important, reflect alterations in intra-abdominal tissue perfusion that are not reflected by systemic macrohemodynamics, and can help clinicians guide therapeutic interventions.

U2 - 10.1053/j.jvca.2023.09.015

DO - 10.1053/j.jvca.2023.09.015

M3 - SCORING: Journal article

C2 - 38114369

VL - 38

SP - 417

EP - 422

JO - J CARDIOTHOR VASC AN

JF - J CARDIOTHOR VASC AN

SN - 1053-0770

IS - 2

ER -