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The soluble transferrin receptor (TfR)-F-Index is not applicable as a test for iron status in patients with chronic lymphocytic leukemia.

Standard

The soluble transferrin receptor (TfR)-F-Index is not applicable as a test for iron status in patients with chronic lymphocytic leukemia. / Metzgeroth, Georgia; Kripp, Melanie; Müller, Nadine; Schultheis, Beate; Bonatz, Karin; Walz, Christoph; Dorn-Beineke, Alexandra; Hastka, Jan.

in: CLIN CHEM LAB MED, Jahrgang 47, Nr. 10, 10, 2009, S. 1291-1295.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Metzgeroth, G, Kripp, M, Müller, N, Schultheis, B, Bonatz, K, Walz, C, Dorn-Beineke, A & Hastka, J 2009, 'The soluble transferrin receptor (TfR)-F-Index is not applicable as a test for iron status in patients with chronic lymphocytic leukemia.', CLIN CHEM LAB MED, Jg. 47, Nr. 10, 10, S. 1291-1295. <http://www.ncbi.nlm.nih.gov/pubmed/19743956?dopt=Citation>

APA

Metzgeroth, G., Kripp, M., Müller, N., Schultheis, B., Bonatz, K., Walz, C., Dorn-Beineke, A., & Hastka, J. (2009). The soluble transferrin receptor (TfR)-F-Index is not applicable as a test for iron status in patients with chronic lymphocytic leukemia. CLIN CHEM LAB MED, 47(10), 1291-1295. [10]. http://www.ncbi.nlm.nih.gov/pubmed/19743956?dopt=Citation

Vancouver

Metzgeroth G, Kripp M, Müller N, Schultheis B, Bonatz K, Walz C et al. The soluble transferrin receptor (TfR)-F-Index is not applicable as a test for iron status in patients with chronic lymphocytic leukemia. CLIN CHEM LAB MED. 2009;47(10):1291-1295. 10.

Bibtex

@article{e47becfbe85a475b8ab290aa258bfb0d,
title = "The soluble transferrin receptor (TfR)-F-Index is not applicable as a test for iron status in patients with chronic lymphocytic leukemia.",
abstract = "BACKGROUND: The soluble transferrin receptor (sTfR) is established as a test for iron deficiency (ID). In chronic lymphocytic leukemia (CLL), sTfR is not reliable for screening for ID as the latter is strongly dependent on tumor burden. METHODS: We investigated whether the influence of the tumor load can be excluded or minimized using the sTfR/log ferritin ratio (TfR-F-Index) and the C-reactive protein (CRP)-adjusted TfR-F-Index in 87 patients with CLL. sTfR was measured nephelometrically (normal: 0.81-1.75 mg/L). A cut-off value of 1.5 for the TfR-F-Index and 0.8 for the CRP-adjusted TfR-F-Index, in patients with a CRP >5 mg/L, was used. RESULTS: All Binet A patients had normal sTfR values (1.34+/-0.2 mg/L), TfR-F-Index (0.67+/-0.2) and a CRP-adjusted TfR-F-Index. In Binet B and C, sTfR and the TfR-F-Index were significantly increased compared to Binet A patients (p",
author = "Georgia Metzgeroth and Melanie Kripp and Nadine M{\"u}ller and Beate Schultheis and Karin Bonatz and Christoph Walz and Alexandra Dorn-Beineke and Jan Hastka",
year = "2009",
language = "Deutsch",
volume = "47",
pages = "1291--1295",
journal = "CLIN CHEM LAB MED",
issn = "1434-6621",
publisher = "Walter de Gruyter GmbH & Co. KG",
number = "10",

}

RIS

TY - JOUR

T1 - The soluble transferrin receptor (TfR)-F-Index is not applicable as a test for iron status in patients with chronic lymphocytic leukemia.

AU - Metzgeroth, Georgia

AU - Kripp, Melanie

AU - Müller, Nadine

AU - Schultheis, Beate

AU - Bonatz, Karin

AU - Walz, Christoph

AU - Dorn-Beineke, Alexandra

AU - Hastka, Jan

PY - 2009

Y1 - 2009

N2 - BACKGROUND: The soluble transferrin receptor (sTfR) is established as a test for iron deficiency (ID). In chronic lymphocytic leukemia (CLL), sTfR is not reliable for screening for ID as the latter is strongly dependent on tumor burden. METHODS: We investigated whether the influence of the tumor load can be excluded or minimized using the sTfR/log ferritin ratio (TfR-F-Index) and the C-reactive protein (CRP)-adjusted TfR-F-Index in 87 patients with CLL. sTfR was measured nephelometrically (normal: 0.81-1.75 mg/L). A cut-off value of 1.5 for the TfR-F-Index and 0.8 for the CRP-adjusted TfR-F-Index, in patients with a CRP >5 mg/L, was used. RESULTS: All Binet A patients had normal sTfR values (1.34+/-0.2 mg/L), TfR-F-Index (0.67+/-0.2) and a CRP-adjusted TfR-F-Index. In Binet B and C, sTfR and the TfR-F-Index were significantly increased compared to Binet A patients (p

AB - BACKGROUND: The soluble transferrin receptor (sTfR) is established as a test for iron deficiency (ID). In chronic lymphocytic leukemia (CLL), sTfR is not reliable for screening for ID as the latter is strongly dependent on tumor burden. METHODS: We investigated whether the influence of the tumor load can be excluded or minimized using the sTfR/log ferritin ratio (TfR-F-Index) and the C-reactive protein (CRP)-adjusted TfR-F-Index in 87 patients with CLL. sTfR was measured nephelometrically (normal: 0.81-1.75 mg/L). A cut-off value of 1.5 for the TfR-F-Index and 0.8 for the CRP-adjusted TfR-F-Index, in patients with a CRP >5 mg/L, was used. RESULTS: All Binet A patients had normal sTfR values (1.34+/-0.2 mg/L), TfR-F-Index (0.67+/-0.2) and a CRP-adjusted TfR-F-Index. In Binet B and C, sTfR and the TfR-F-Index were significantly increased compared to Binet A patients (p

M3 - SCORING: Zeitschriftenaufsatz

VL - 47

SP - 1291

EP - 1295

JO - CLIN CHEM LAB MED

JF - CLIN CHEM LAB MED

SN - 1434-6621

IS - 10

M1 - 10

ER -