The role of spousal loss in the development of depressive symptoms in the elderly - implications for diagnostic systems
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The role of spousal loss in the development of depressive symptoms in the elderly - implications for diagnostic systems. / Sikorski, Claudia; Luppa, Melanie; Heser, Kathrin; Ernst, Anette; Lange, Carolin; Werle, Jochen; Bickel, Horst; Mösch, Edelgard; Wiese, Birgitt; Prokein, Jana; Fuchs, Angela; Pentzek, Michael; König, Hans-Helmut; Brettschneider, Christian; Scherer, Martin; Maier, Wolfgang; Weyerer, Siegfried; Riedel-Heller, Steffi G; AgeCoDe Study Group.
in: J AFFECT DISORDERS, Jahrgang 161, 01.06.2014, S. 97-103.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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T1 - The role of spousal loss in the development of depressive symptoms in the elderly - implications for diagnostic systems
AU - Sikorski, Claudia
AU - Luppa, Melanie
AU - Heser, Kathrin
AU - Ernst, Anette
AU - Lange, Carolin
AU - Werle, Jochen
AU - Bickel, Horst
AU - Mösch, Edelgard
AU - Wiese, Birgitt
AU - Prokein, Jana
AU - Fuchs, Angela
AU - Pentzek, Michael
AU - König, Hans-Helmut
AU - Brettschneider, Christian
AU - Scherer, Martin
AU - Maier, Wolfgang
AU - Weyerer, Siegfried
AU - Riedel-Heller, Steffi G
AU - AgeCoDe Study Group
AU - Bussche van den, Hendrik
N1 - Copyright © 2014 Elsevier B.V. All rights reserved.
PY - 2014/6/1
Y1 - 2014/6/1
N2 - BACKGROUND: In the revised version of the Diagnostic and Statistical Manual of Mental Disorders (DSM) the Mood Disorder Workgroup for DSM-V the bereavement exclusion criterion for the diagnosis of major depression has been eliminated.AIM: To investigate the impact of bereavement on the incidence of depression and depressive symptoms in the elderly.METHOD: Participants over 75 years from the longitudinal German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe) that were still married at baseline were investigated (n=1,193). Data from four follow-ups (time frame: 6 years) were investigated. The response rate at baseline was 50.3%. Three clinical endpoints were analyzed: depressive symptoms according to Geriatric Depression Scale (1) GDS≥6, (2) GDS≥10, and (3) Major Depression (MD). The effect of loss was investigated using random-effects regression models.RESULTS: Experiencing a loss of spouse was predictive of a higher incidence in GDS≥6 (OR 4.52, 95% CI 2.6-7.9) and 10 (OR 5.59, 95% CI 1.8-17.0) even after adjusting for age, gender, impairment at baseline, and GDS score at baseline. Associations with MD were not significant (OR 1.77, 96% CI 0.9-3.5).CONCLUSIONS: Older adults experiencing the loss of their spouse are more likely to display elevated levels of depressive symptoms, that may reach a concerning level of severity.
AB - BACKGROUND: In the revised version of the Diagnostic and Statistical Manual of Mental Disorders (DSM) the Mood Disorder Workgroup for DSM-V the bereavement exclusion criterion for the diagnosis of major depression has been eliminated.AIM: To investigate the impact of bereavement on the incidence of depression and depressive symptoms in the elderly.METHOD: Participants over 75 years from the longitudinal German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe) that were still married at baseline were investigated (n=1,193). Data from four follow-ups (time frame: 6 years) were investigated. The response rate at baseline was 50.3%. Three clinical endpoints were analyzed: depressive symptoms according to Geriatric Depression Scale (1) GDS≥6, (2) GDS≥10, and (3) Major Depression (MD). The effect of loss was investigated using random-effects regression models.RESULTS: Experiencing a loss of spouse was predictive of a higher incidence in GDS≥6 (OR 4.52, 95% CI 2.6-7.9) and 10 (OR 5.59, 95% CI 1.8-17.0) even after adjusting for age, gender, impairment at baseline, and GDS score at baseline. Associations with MD were not significant (OR 1.77, 96% CI 0.9-3.5).CONCLUSIONS: Older adults experiencing the loss of their spouse are more likely to display elevated levels of depressive symptoms, that may reach a concerning level of severity.
U2 - 10.1016/j.jad.2014.02.033
DO - 10.1016/j.jad.2014.02.033
M3 - SCORING: Journal article
C2 - 24751315
VL - 161
SP - 97
EP - 103
JO - J AFFECT DISORDERS
JF - J AFFECT DISORDERS
SN - 0165-0327
ER -