The role of neck adipose tissue in lymph node metastasis of head and neck cancer
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The role of neck adipose tissue in lymph node metastasis of head and neck cancer. / Pan, Yiqi; Xu, Ying; Fan, Cui; Miao, Xiangwan; Shen, Yilin; Wang, Quan; Wu, Jichang; Hu, Haixia; Wang, Hao; Xiang, Mingliang; Ye, Bin.
in: FRONT ONCOL, Jahrgang 14, 2024, S. 1390824.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - The role of neck adipose tissue in lymph node metastasis of head and neck cancer
AU - Pan, Yiqi
AU - Xu, Ying
AU - Fan, Cui
AU - Miao, Xiangwan
AU - Shen, Yilin
AU - Wang, Quan
AU - Wu, Jichang
AU - Hu, Haixia
AU - Wang, Hao
AU - Xiang, Mingliang
AU - Ye, Bin
N1 - Copyright © 2024 Pan, Xu, Fan, Miao, Shen, Wang, Wu, Hu, Wang, Xiang and Ye.
PY - 2024
Y1 - 2024
N2 - Previous studies indicated that adipose tissue significantly influences cancer invasion and lymphatic metastasis. However, the impact of neck adipose tissue (NAT) on lymph node metastasis associated with head and neck cancer remains ambiguous. Here, we systematically assess the classification and measurement criteria of NAT and evaluate the association of adipose tissue and cancer-associated adipocytes with head and neck cancer. We delve into the potential mechanisms by which NAT facilitate cervical lymph node metastasis in head and neck cancer, particularly through the secretion of adipokines such as leptin, adiponectin, and Interleukin-6. Our aim is to elucidate the role of NAT in the progression and metastasis of head and neck cancer, offering new insights into prevention and treatment.
AB - Previous studies indicated that adipose tissue significantly influences cancer invasion and lymphatic metastasis. However, the impact of neck adipose tissue (NAT) on lymph node metastasis associated with head and neck cancer remains ambiguous. Here, we systematically assess the classification and measurement criteria of NAT and evaluate the association of adipose tissue and cancer-associated adipocytes with head and neck cancer. We delve into the potential mechanisms by which NAT facilitate cervical lymph node metastasis in head and neck cancer, particularly through the secretion of adipokines such as leptin, adiponectin, and Interleukin-6. Our aim is to elucidate the role of NAT in the progression and metastasis of head and neck cancer, offering new insights into prevention and treatment.
U2 - 10.3389/fonc.2024.1390824
DO - 10.3389/fonc.2024.1390824
M3 - SCORING: Review article
C2 - 38800384
VL - 14
SP - 1390824
JO - FRONT ONCOL
JF - FRONT ONCOL
SN - 2234-943X
ER -